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PARATHYROID
    GLAND
    By: Steph and Lindsey

1
SIZE AND LOCATION




                    2
FUNCTION OF PARATHYROID
GLAND
  Produce  PTH
  To control calcium within the blood to help
   maintain strong bones




                                                 3
HORMONES SECRETED FROM PARATHYROID
GLAND
 Secreteparathyroid
 hormone (PTH)
  Humoral stimuli
  Most important regulator
   of Ca2+ homeostasis of
   the blood
  Hypercalcemic hormone




                                4
HYPERPARATHYROIDISM
   Etiology                    Pathogenesis
     Overproduction of           Bone Pain
       the cells secreting        Depression
       PTH                        Frequent urination
     Parathyroid
                                  Kidney stones
       develops a tumor
                                  Nausea
                                  Loss of appetite


                                Treatment
                                   Remove the tumor
                                    surgically
                                                        5
HYPOPARATHYROIDISM
   Etiology                      Pathogenesis
     Family History                Heavier periods in
     Autoimmune Disorder            females
     Excessive radiation
                                    Cataracts
      treatment
     Low levels of Mg in           Tingling sensations
      blood                         Muscles spasms
   Treatment                       Dry hair and skin;
      restore the Ca and            brittle nails
       mineral balance in           Weakened tooth
       the body                      enamel in kids
         Take vitamins with

          Calcium and                                      6
          Vitamin D
OSTEOPOROSIS
 Etiology
    Loss of Calcium
    Too much PTH
 Pathogenesis
    "Thin Bones"
    Bones break and
     fracture easier
    Loss of energy
    Feel old
    Bones hurt
 Treatment
    Remove the bad      7
     parathyroid gland
PARATHYROID CANCER
   Etiology                   Pathogenesis
     Out of control PTH
                                 Weakness
       production
     Family history             Lump in neck
     Hyperparathyroidism        Trouble swallowing
                                 Loss of appetite
                                 Unquenchable thirst


                               Treatment
                                  Surgery
                                  Radiation therapy

                                                       8
WEBSITES
 http://www.nlm.nih.gov/medlineplus/parathyroiddiso
  rders.html
 http://www.parathyroid.com/parathyroid-
  function.htm
 http://www.endocrineweb.com/conditions/parathyroi
  d/parathyroid-cancer
 https://www.clinicalkey.com/topics/endocrinology/hy
  perparathyroidism.html



                                                        9

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Parathyroid Gland and Disorders

  • 1. PARATHYROID GLAND By: Steph and Lindsey 1
  • 3. FUNCTION OF PARATHYROID GLAND  Produce PTH  To control calcium within the blood to help maintain strong bones 3
  • 4. HORMONES SECRETED FROM PARATHYROID GLAND  Secreteparathyroid hormone (PTH)  Humoral stimuli  Most important regulator of Ca2+ homeostasis of the blood  Hypercalcemic hormone 4
  • 5. HYPERPARATHYROIDISM  Etiology  Pathogenesis  Overproduction of  Bone Pain the cells secreting  Depression PTH  Frequent urination  Parathyroid  Kidney stones develops a tumor  Nausea  Loss of appetite  Treatment  Remove the tumor surgically 5
  • 6. HYPOPARATHYROIDISM  Etiology  Pathogenesis  Family History  Heavier periods in  Autoimmune Disorder females  Excessive radiation  Cataracts treatment  Low levels of Mg in  Tingling sensations blood  Muscles spasms  Treatment  Dry hair and skin;  restore the Ca and brittle nails mineral balance in  Weakened tooth the body enamel in kids  Take vitamins with Calcium and 6 Vitamin D
  • 7. OSTEOPOROSIS  Etiology  Loss of Calcium  Too much PTH  Pathogenesis  "Thin Bones"  Bones break and fracture easier  Loss of energy  Feel old  Bones hurt  Treatment  Remove the bad 7 parathyroid gland
  • 8. PARATHYROID CANCER  Etiology  Pathogenesis  Out of control PTH  Weakness production  Family history  Lump in neck  Hyperparathyroidism  Trouble swallowing  Loss of appetite  Unquenchable thirst  Treatment  Surgery  Radiation therapy 8
  • 9. WEBSITES  http://www.nlm.nih.gov/medlineplus/parathyroiddiso rders.html  http://www.parathyroid.com/parathyroid- function.htm  http://www.endocrineweb.com/conditions/parathyroi d/parathyroid-cancer  https://www.clinicalkey.com/topics/endocrinology/hy perparathyroidism.html 9

Notas do Editor

  1. -located on the thyroid gland. -Most people have four pea-sized parathyroid glands ~relatively small gland compared to the other glands and organs around it.
  2. -PTH is a hypercalcemic hormone because it acts to increase blood levels of Calcium-Decreasing blood Ca levels prompt the release of PTH, which causes blood Ca levels to rise, ending the stimulus for PTH release
  3. -surgery can be done in 13 minutes or less
  4. -Not enough Ca; too much Phosphorous-cataracts: cloudy lens-muscle spasms = tetany-Hypoparaythroidism can be acquired from accidental removal or damage to parathyroid gland during surgery (i.e. to remove throat cancer) (less common now)-usually a chronic disorder
  5. -extremely rare with about one case in every 1,000 patients with parathyroid disease-symptoms are similar to those of hyperparathyroidism because both involve too much PTH-All patients with hyperparathyroidism have elevated parathyroid hormone in their blood, those with benign disease tend to have levels in the "hundreds" where as those with parathyroid cancer tend to have values in the "thousands." -The parathyroid gland and the half of the thyroid on the same side as the cancer is typically removed.