A research project and presentation I worked on in my Medical Nutrition Therapy class, which discusses the link between moderate consumption of red wine and its effect on breast cancer
4. 1 in 8 women will get breast cancer during
their lifetime
Based on this statistic, 10 people in HNF 320
will develop breast cancer in their lifetime
1/3 of cancers are linked to diet
3-4 million cancer cases can be prevented
each year by change in diet
Grapes are most widely consumed fruit
worldwide
Contain polyphenols
5. Antioxidants found in the seeds, skins, and
stems of grapes
Beneficial health effects including inhibiting
cancer growth
Resveratrol is a powerful polyphenol in red
wine and prevents tumor growth
6. Estrogen:
hormone that contributes to
normal breast and sexual development
Estrogenstimulates cell division, meaning
excessive amounts can lead to tumor
development
Polyphenols decrease estrogen levels
Phytoestrogens are estrogens found in plants
7. Commonly found in tofu, soy beans, whole
grains, fruits, and vegetables
Diethigh in phytoestrogens can decrease
one’s risk for breast cancer
If phytoestrogens bind to the estrogen receptor
instead of the stronger human made estrogen
less cell division will occur
8. Objective: To determine the anti-proliferative affect
of red wine concentrate on the hormone sensitive
breast cancer cells
Results: Low concentrations of polyphenols, and
consecutively, consumptions of wine or other
polyphenol rich foods and beverages could have a
beneficial anti-proliferative affect on breast cancer
cell growth
9. Objective: To determine whether Resveratrol
may be considered a phytoestrogen
Researchers found resveratrol binds to the
human estrogen competeing with human made
estrogen
Results: Resveratrol is a phytoestrogen, meaning
Resveratrol plays a role in reducing breast
cancer risk
10. Objective: To determine whether Resveratrol can
be a cancer chemopreventive agent
Used a mouse mammory gland culture model of
carcinogenesis to test activity resveratrol
Results: found to inhibit tumor initiation,
promotion, and progression
11. Positive correlation between red wine
consumption and decrease breast cancer risk
Hypothesis is accepted
Polyphenols have been shown to be beneficial in
decreasing breast cancer risk
More research is needed, especially clinical trials
involving humans
12. Moderate consumption of red wine can be
beneficial
Grapes contain the polyphenols, not alcohol
Eating grapes or drinking 100% natural grape
juice can offer similar protection against breast
cancer
13. Bothmen and women should have a diet rich
in polyphenols (antioxidants)
14. Rewards:
Became knowledgeable on importance of diet
with breast health
Became more familiar with researching
Challenges:
Difficult to compile all of our information
Interpreting the research articles
15. Polyphenols are
A. Grapes
B. Antioxidants
C. A type of wine
D. Cancer causing substance
B. Antioxidant
16. True or false
Resveratrol is a human made estrogen