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Vascular System

Dr. Samar Asker
Arteries
Large Arteries: aorta
caries blood from the
heart.
Medium-sized arteries:
cary blood to organs
Small Arteries
(arterioles):regulate blood
flow to capillaries.
General Structure of Blood Vessels
T.Intima
T.Media
T.Adventitia
Large
arteries
Aorta
Tunica intima 10%
simple squamous
epithelium
Subendothelial C.T.
rich in elastic fiber.
Undifferentiated
Internal elastic lamina.
Tunica Media70%:
Fenestrated elastic
membrane (40-70
layer)
Smooth muscle in()
Collagen fibers.
Tunica adventitia 20%:
 Loose CT rich in elastic
fibers.

 Contain vasa vasora which
is a small blood vessels
that supply the outer part
of T. media & T.
adventitia
10%

70%

20%
Medium sized artery
Wall

Thick wall.

Lumen

Narrow lumen.
Not contain blood after
death.
No valve in the lumen.

Flow of
Blood

It has a rapid flow of
arterial blood.

Medium sized vein
Thin wall.
Wide lumen usually contains
blood after death.
Valve present.
It has a slow flow of venous
blood.
T.
Intima

Medium sized artery
Thick.
Folded due to
internal elastic
lamina.

Medium sized vein
Thin.
Not Folded.
Medium sized artery
T. Media

Thick.
Some elastic membrane.
External elastic lamina may
be present

Adventitia

Thin and contain elastic
fibers.

Medium sized vein

Thin.
Formed of few smooth
muscle fibers.
No external elastic lamina.
Thicker
No elastic fibers
Peripheral circulation
Arterioles give plexus of
capillaries to supply tissues
The Blood capillaries
Narrow vessels
formed by rolling
of an endothelial
cell
Length: 0.251mm
Diameter: 8 μm.
1 layer of endothelial cells
Resting on basement membrane
Which split to enclose pericytes
Types of
capillaries
Continuous capillaries:
Continuous endothelium
(no pores)
Continuous basement
membrane
Sites:
C. T., bone, brain , skin
and exocrine glands.
Fenestrated or visceral:
Endothelium has pores closed
by membrane or diaphragms
except renal capillaries
Site:
Intestine
Endocrine glands.
Glomerular capillary of kidney,
Sinusoidal capillaries:
Dilated irregular capillaries,
(5-40) µm.
Fenestrated endothelium have
pores without diaphragms.
The basement membrane
either non continuous or absent.
Macrophages extend pseudopodia inside () the endothelial
cells to engulf any foreign body.
Sites :
In bone marrow:Carry blood cells, to the
circulation.
In spleen:
Carry stored blood cells
to circulation & filter the
blood.
liver: carry
plasma proteins to
blood
In endocrine
glands: carry
hormones to blood.
Blood Vessels

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Blood Vessels