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Anaemia during Pregnancy and
in the Postpartum period
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
BEMoC - Presentation 7 (a)
Session 7a
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
2
Session Objectives
 To be able to:
• Diagnose Anaemia & Malaria
• Treat Anaemia & Malaria
• Prevent Anaemia & Malaria
 Refer cases of Severe Anaemia to FRU
3
Anaemia
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
4
Anaemia in Pregnancy
Definition
 Anaemia is defined as Hb level < 11gm% in
pregnancy or immediate post partum period.
 Anaemia is grouped as (ICMR Classification)
• Mild (10-11gm %)
• Moderate (7-9.9 gm %)
• Severe (4 – 6.9gm %)
• Very severe (<4 gm %)
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
5
Diagnosis of anaemia and its severity
Symptoms & signs Probable Diagnosis (ICMR
Classification)
Haemoglobin >11 g/dl
No pallor
No clinical Anaemia
Hemoglobin 10-10.9 g/dl Mild Anaemia
Haemoglobin 7-9.9g/dl
OR
Palmar or conjunctival pallor
Moderate Anaemia
Haemoglobin 4-6.9 g/dl
AND/ OR
Severe palmar and conjunctival pallor or any
pallor with any of the following:
* >30 breaths/minute
* Easy fatiguability
* Breathlessness at rest
Severe Anaemia
Haemoglobin <4 g/dl
AND/ OR as severe anemia
Very Severe Anaemia
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
6
Management
 Depends on :
• Severity of anaemia
• Gestational age
 Iron administered either orally or parentally
requires a minimum period of 4 - 6 wks to raise
the Hb to normal levels
 Nutritional counselling for iron rich food(like
jaggery, spinach etc)
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
7
Management
 For prophylaxis: 1 IFA tablet (with 100 mg elemental iron and 0.5 mg
folic acid) once daily for 100 days starting after the 1st trimester.
 Mild to Moderate anemia :
• IFA tabs (100 mg elemental iron + 0.5 mg folic acid) twice daily
and to be continued during postpartum period.
• Administer parenteral iron preparation if there is non compliance /
intolerance to oral iron.
 Moderate and Severe anaemia: May receive antihelminthic drugs
(Tab. Mebendazole 100 mg bd for 3 days or Tab. Albendazole 400 mg
single dose) especially in hookworm endemic areas during 2nd/3rd
trimesters of pregnancy.
 Severe anemia :
• Refer to FRU for further investigations & treatment.
• This woman might need a blood transfusion.
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
8
Management- Mild & Moderate Anaemia
 Give IFA tablet (with 100 mg elemental iron and 0.5 mg folic
acid) twice daily for 100 days & to be continued in post partum
period for 3 months.
 Counsel the woman on the need for compliance with treatment.
 Nutritional Counselling for Iron Rich Food
• Administer parenteral iron preparation if there is non
compliance / intolerance to oral iron.
 Give LLINs if you are in a malaria-endemic zone.
 Give the woman an antihelminthic for deworming (Tab.
Mebendazole 500 mg stat , or Albendazole 400 mg stat),
especially if you are in a hookworm-endemic area.
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
9
Management – Mild & Moderate anaemia
 Reassess after one month.
 If Hb level increases continue treatment
 If no improvement refer to FRU for further management
 If the woman of mild & moderate anemia reports in
labour
• Conduct the delivery with emphasis on AMTSL
• Monitor her for 48 hours
• Check Hb level after 3 days
• Prescribe I tab (100 mg) of IFA twice daily for 6
months post partum
• Reassess her in the next postnatal visit at 6 weeks &
refer to FRU if no improvement
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
10
Management – Severe anaemia
 Should ideally be managed in a CEmOC facility where
blood transfusion facility is available
 Refer her to FRU at the earliest
 If she reports in first stage of labor and there is
sufficient time or post partum refer her to FRU
 If she reports in active labor with delivery imminent,
• Conduct the delivery with minimal possible blood
loss (AMTSL)
• Monitor the vital signs intensively during the delivery
• Refer urgently to FRU after stabilizing her condition
 Follow up the woman in two weeks to check the clinical
progress, test results and compliance with treatment of
double dose of iron (1 tablet twice a day) for 6 months
postpartum.
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
11
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
12
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
14
Counselling – Diet & Rest
 Reassure the mother that she can eat normal food ; these will not
harm the breast fed baby
 Diet to be rich in iron & fibre
 Discuss about food taboos especially against food that are
nutritionally healthy
 Talk to family members like mother in law , husband to encourage
them to ensure that the woman easts enough & avoids heavy
physical work
 Take care of the mother so that she can take care of the baby
 Counselling on diet especially for adolescent mother
 IFA Supplementation
 Women with normal Hb are advised to take 1 IFA tablet daily for 3
months
 If Hb below 11 gm%, advise her to take 2 IFA tabs daily and repeat
Hb after 1 month
 Family support specially for girl child
 Rest to the Mother
15
Malaria
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
16
Screening and prophylaxis of malaria during
pregnancy
 No prophylaxis is recommended but
insecticide treated bed nets/LLIN be given on
priority basis to the all pregnant women in
vulnerable population
 High malaria endemic areas: Routine testing
& screening for malaria on the 1st ANC & in
each month by RDK tests even if she does not
manifest any malaria symptoms
 Non endemic areas: All clinical suspected
cases (as per NVBDCP guidelines) should
preferably be investigated for malaria by RDK
17
Treatment in 1st
Trimester
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
18
Treatment: Uncomplicated Malaria
P. vivax
Chloroquine base to be
given as under:
Day 1 4 tabs @10mg/kg
Day 2 4 tabs @10mg/kg
Day 3 2 tabs@5 mg/kg
P. falciparum
Quinine (as tablets) 10
mg. quinine salt/kg. body
weight 3 times daily for 7
days.
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
19
Treatment: Severe and complicated malaria
 Parenteral Quinine is the drug of choice in first trimester
 Loading dose :
• 20 mg/kg. body weight on admission (I.V. infusion in 5% Dextrose/
dextrose saline over a period of 4 hours)
• May not be given if the patient has already received quinine or if clinician
feels inappropriate.
 Maintenance dose:
• 10 mg./kg. bw 8 hourly
• infusion rate should not exceed 5 mg salt/kg bw per hour
 NEVER give bolus injection of Quinine
 Parenteral Quinine given for minimum of 48 hours & once the patient
tolerates oral therapy, follow-up treatment is as under:
• Quinine 10 mg./kg. bw three times a day to complete a course of 7 days
PLUS
• Clindamycin 10mg./kg. bw 12 hrly should be given for 7 days
 If Parenteral Quinine to be given after 48 hours, reduce dose to 7 mg/kg
body weight 8 hourly.
 Parenteral Treatment should be given for a minimum of 24 hours once
started
 If Quinine unavailable, artemisin derivatives may be used
20
Treatment of Malaria in
2nd
& 3rd
Trimesters
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
21
TREATMENT:
P. vivax
Chloroquine base to be
given as under:
Day 1 4 tabs @10mg/kg
Day 2 4 tabs @10mg/kg
Day 3 2 tabs@5 mg/kg
P. falciparum
ACT to be given as
under:
1st
day
2nd
day
3rd
day
AS 4 tabs 4 tabs 4 tabs
SP 3 tabs Nil Nil
AS- artesunate 50 mg
SP-Sulfadoxine 500 mg +
Pyrimethamine 25 mg
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
22
Treatment: Severe and complicated malaria
 Parenteral artemisin derivatives preferred in 2nd
& 3rd
trimesters.
 To be given as under:
• Artesunate
 2.4 mg/kg bw iv or im given on admission then at 12
hours & 24 hours, then once a day
 Care should be taken to dilute artesunate powder in 5%
Sodium bicarbonate provided in the pack
• Artemether
 3.2 mg/kg body weight im given on admission then 1.6
mg/kg bw per day
• Α-βArteether
 150 mg daily im for 3 days
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
23
Side effects of Quinine
 Metallic taste
 Nausea
 Tinnitus
 Hypoglycaemia
Note:
 Pregnant women should not take quinine on an
empty stomach and should eat regularly, while on
quinine treatment
 No special diet is needed
 Primaquine is contraindicated during pregnancy.
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
24
Key Messages
 Prophylaxis of anaemia
 Management of Anaemia
 Management of Complicated and
Uncomplicated Anaemia in First, Second &
Third Trimesters
 Referral of Severe Anaemia Cases
ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
25
Case Studies
 Case Study Number 23 on page number 88 &
89 of Trainees Hands Book
26
Thank you

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7a anemia and other common problems 13-sept 2011

  • 1. 1 Anaemia during Pregnancy and in the Postpartum period Maternal Health Division Ministry of Health & Family Welfare Government of India BEMoC - Presentation 7 (a) Session 7a
  • 2. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 2 Session Objectives  To be able to: • Diagnose Anaemia & Malaria • Treat Anaemia & Malaria • Prevent Anaemia & Malaria  Refer cases of Severe Anaemia to FRU
  • 4. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 4 Anaemia in Pregnancy Definition  Anaemia is defined as Hb level < 11gm% in pregnancy or immediate post partum period.  Anaemia is grouped as (ICMR Classification) • Mild (10-11gm %) • Moderate (7-9.9 gm %) • Severe (4 – 6.9gm %) • Very severe (<4 gm %)
  • 5. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 5 Diagnosis of anaemia and its severity Symptoms & signs Probable Diagnosis (ICMR Classification) Haemoglobin >11 g/dl No pallor No clinical Anaemia Hemoglobin 10-10.9 g/dl Mild Anaemia Haemoglobin 7-9.9g/dl OR Palmar or conjunctival pallor Moderate Anaemia Haemoglobin 4-6.9 g/dl AND/ OR Severe palmar and conjunctival pallor or any pallor with any of the following: * >30 breaths/minute * Easy fatiguability * Breathlessness at rest Severe Anaemia Haemoglobin <4 g/dl AND/ OR as severe anemia Very Severe Anaemia
  • 6. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 6 Management  Depends on : • Severity of anaemia • Gestational age  Iron administered either orally or parentally requires a minimum period of 4 - 6 wks to raise the Hb to normal levels  Nutritional counselling for iron rich food(like jaggery, spinach etc)
  • 7. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 7 Management  For prophylaxis: 1 IFA tablet (with 100 mg elemental iron and 0.5 mg folic acid) once daily for 100 days starting after the 1st trimester.  Mild to Moderate anemia : • IFA tabs (100 mg elemental iron + 0.5 mg folic acid) twice daily and to be continued during postpartum period. • Administer parenteral iron preparation if there is non compliance / intolerance to oral iron.  Moderate and Severe anaemia: May receive antihelminthic drugs (Tab. Mebendazole 100 mg bd for 3 days or Tab. Albendazole 400 mg single dose) especially in hookworm endemic areas during 2nd/3rd trimesters of pregnancy.  Severe anemia : • Refer to FRU for further investigations & treatment. • This woman might need a blood transfusion.
  • 8. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 8 Management- Mild & Moderate Anaemia  Give IFA tablet (with 100 mg elemental iron and 0.5 mg folic acid) twice daily for 100 days & to be continued in post partum period for 3 months.  Counsel the woman on the need for compliance with treatment.  Nutritional Counselling for Iron Rich Food • Administer parenteral iron preparation if there is non compliance / intolerance to oral iron.  Give LLINs if you are in a malaria-endemic zone.  Give the woman an antihelminthic for deworming (Tab. Mebendazole 500 mg stat , or Albendazole 400 mg stat), especially if you are in a hookworm-endemic area.
  • 9. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 9 Management – Mild & Moderate anaemia  Reassess after one month.  If Hb level increases continue treatment  If no improvement refer to FRU for further management  If the woman of mild & moderate anemia reports in labour • Conduct the delivery with emphasis on AMTSL • Monitor her for 48 hours • Check Hb level after 3 days • Prescribe I tab (100 mg) of IFA twice daily for 6 months post partum • Reassess her in the next postnatal visit at 6 weeks & refer to FRU if no improvement
  • 10. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 10 Management – Severe anaemia  Should ideally be managed in a CEmOC facility where blood transfusion facility is available  Refer her to FRU at the earliest  If she reports in first stage of labor and there is sufficient time or post partum refer her to FRU  If she reports in active labor with delivery imminent, • Conduct the delivery with minimal possible blood loss (AMTSL) • Monitor the vital signs intensively during the delivery • Refer urgently to FRU after stabilizing her condition  Follow up the woman in two weeks to check the clinical progress, test results and compliance with treatment of double dose of iron (1 tablet twice a day) for 6 months postpartum.
  • 11. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 11
  • 12. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 12
  • 13. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 14 Counselling – Diet & Rest  Reassure the mother that she can eat normal food ; these will not harm the breast fed baby  Diet to be rich in iron & fibre  Discuss about food taboos especially against food that are nutritionally healthy  Talk to family members like mother in law , husband to encourage them to ensure that the woman easts enough & avoids heavy physical work  Take care of the mother so that she can take care of the baby  Counselling on diet especially for adolescent mother  IFA Supplementation  Women with normal Hb are advised to take 1 IFA tablet daily for 3 months  If Hb below 11 gm%, advise her to take 2 IFA tabs daily and repeat Hb after 1 month  Family support specially for girl child  Rest to the Mother
  • 15. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 16 Screening and prophylaxis of malaria during pregnancy  No prophylaxis is recommended but insecticide treated bed nets/LLIN be given on priority basis to the all pregnant women in vulnerable population  High malaria endemic areas: Routine testing & screening for malaria on the 1st ANC & in each month by RDK tests even if she does not manifest any malaria symptoms  Non endemic areas: All clinical suspected cases (as per NVBDCP guidelines) should preferably be investigated for malaria by RDK
  • 17. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 18 Treatment: Uncomplicated Malaria P. vivax Chloroquine base to be given as under: Day 1 4 tabs @10mg/kg Day 2 4 tabs @10mg/kg Day 3 2 tabs@5 mg/kg P. falciparum Quinine (as tablets) 10 mg. quinine salt/kg. body weight 3 times daily for 7 days.
  • 18. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 19 Treatment: Severe and complicated malaria  Parenteral Quinine is the drug of choice in first trimester  Loading dose : • 20 mg/kg. body weight on admission (I.V. infusion in 5% Dextrose/ dextrose saline over a period of 4 hours) • May not be given if the patient has already received quinine or if clinician feels inappropriate.  Maintenance dose: • 10 mg./kg. bw 8 hourly • infusion rate should not exceed 5 mg salt/kg bw per hour  NEVER give bolus injection of Quinine  Parenteral Quinine given for minimum of 48 hours & once the patient tolerates oral therapy, follow-up treatment is as under: • Quinine 10 mg./kg. bw three times a day to complete a course of 7 days PLUS • Clindamycin 10mg./kg. bw 12 hrly should be given for 7 days  If Parenteral Quinine to be given after 48 hours, reduce dose to 7 mg/kg body weight 8 hourly.  Parenteral Treatment should be given for a minimum of 24 hours once started  If Quinine unavailable, artemisin derivatives may be used
  • 19. 20 Treatment of Malaria in 2nd & 3rd Trimesters
  • 20. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 21 TREATMENT: P. vivax Chloroquine base to be given as under: Day 1 4 tabs @10mg/kg Day 2 4 tabs @10mg/kg Day 3 2 tabs@5 mg/kg P. falciparum ACT to be given as under: 1st day 2nd day 3rd day AS 4 tabs 4 tabs 4 tabs SP 3 tabs Nil Nil AS- artesunate 50 mg SP-Sulfadoxine 500 mg + Pyrimethamine 25 mg
  • 21. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 22 Treatment: Severe and complicated malaria  Parenteral artemisin derivatives preferred in 2nd & 3rd trimesters.  To be given as under: • Artesunate  2.4 mg/kg bw iv or im given on admission then at 12 hours & 24 hours, then once a day  Care should be taken to dilute artesunate powder in 5% Sodium bicarbonate provided in the pack • Artemether  3.2 mg/kg body weight im given on admission then 1.6 mg/kg bw per day • Α-βArteether  150 mg daily im for 3 days
  • 22. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 23 Side effects of Quinine  Metallic taste  Nausea  Tinnitus  Hypoglycaemia Note:  Pregnant women should not take quinine on an empty stomach and should eat regularly, while on quinine treatment  No special diet is needed  Primaquine is contraindicated during pregnancy.
  • 23. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 24 Key Messages  Prophylaxis of anaemia  Management of Anaemia  Management of Complicated and Uncomplicated Anaemia in First, Second & Third Trimesters  Referral of Severe Anaemia Cases
  • 24. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD Maternal Health Division Ministry of Health & Family Welfare Government of India 25 Case Studies  Case Study Number 23 on page number 88 & 89 of Trainees Hands Book