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Anaemia during Pregnancy and
in the Postpartum period
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
BEMoC - Presentation 7 (a)
Session 7a
2. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
2
Session Objectives
To be able to:
• Diagnose Anaemia & Malaria
• Treat Anaemia & Malaria
• Prevent Anaemia & Malaria
Refer cases of Severe Anaemia to FRU
4. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
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Anaemia in Pregnancy
Definition
Anaemia is defined as Hb level < 11gm% in
pregnancy or immediate post partum period.
Anaemia is grouped as (ICMR Classification)
• Mild (10-11gm %)
• Moderate (7-9.9 gm %)
• Severe (4 – 6.9gm %)
• Very severe (<4 gm %)
5. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
5
Diagnosis of anaemia and its severity
Symptoms & signs Probable Diagnosis (ICMR
Classification)
Haemoglobin >11 g/dl
No pallor
No clinical Anaemia
Hemoglobin 10-10.9 g/dl Mild Anaemia
Haemoglobin 7-9.9g/dl
OR
Palmar or conjunctival pallor
Moderate Anaemia
Haemoglobin 4-6.9 g/dl
AND/ OR
Severe palmar and conjunctival pallor or any
pallor with any of the following:
* >30 breaths/minute
* Easy fatiguability
* Breathlessness at rest
Severe Anaemia
Haemoglobin <4 g/dl
AND/ OR as severe anemia
Very Severe Anaemia
6. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
6
Management
Depends on :
• Severity of anaemia
• Gestational age
Iron administered either orally or parentally
requires a minimum period of 4 - 6 wks to raise
the Hb to normal levels
Nutritional counselling for iron rich food(like
jaggery, spinach etc)
7. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
7
Management
For prophylaxis: 1 IFA tablet (with 100 mg elemental iron and 0.5 mg
folic acid) once daily for 100 days starting after the 1st trimester.
Mild to Moderate anemia :
• IFA tabs (100 mg elemental iron + 0.5 mg folic acid) twice daily
and to be continued during postpartum period.
• Administer parenteral iron preparation if there is non compliance /
intolerance to oral iron.
Moderate and Severe anaemia: May receive antihelminthic drugs
(Tab. Mebendazole 100 mg bd for 3 days or Tab. Albendazole 400 mg
single dose) especially in hookworm endemic areas during 2nd/3rd
trimesters of pregnancy.
Severe anemia :
• Refer to FRU for further investigations & treatment.
• This woman might need a blood transfusion.
8. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
8
Management- Mild & Moderate Anaemia
Give IFA tablet (with 100 mg elemental iron and 0.5 mg folic
acid) twice daily for 100 days & to be continued in post partum
period for 3 months.
Counsel the woman on the need for compliance with treatment.
Nutritional Counselling for Iron Rich Food
• Administer parenteral iron preparation if there is non
compliance / intolerance to oral iron.
Give LLINs if you are in a malaria-endemic zone.
Give the woman an antihelminthic for deworming (Tab.
Mebendazole 500 mg stat , or Albendazole 400 mg stat),
especially if you are in a hookworm-endemic area.
9. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
9
Management – Mild & Moderate anaemia
Reassess after one month.
If Hb level increases continue treatment
If no improvement refer to FRU for further management
If the woman of mild & moderate anemia reports in
labour
• Conduct the delivery with emphasis on AMTSL
• Monitor her for 48 hours
• Check Hb level after 3 days
• Prescribe I tab (100 mg) of IFA twice daily for 6
months post partum
• Reassess her in the next postnatal visit at 6 weeks &
refer to FRU if no improvement
10. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
10
Management – Severe anaemia
Should ideally be managed in a CEmOC facility where
blood transfusion facility is available
Refer her to FRU at the earliest
If she reports in first stage of labor and there is
sufficient time or post partum refer her to FRU
If she reports in active labor with delivery imminent,
• Conduct the delivery with minimal possible blood
loss (AMTSL)
• Monitor the vital signs intensively during the delivery
• Refer urgently to FRU after stabilizing her condition
Follow up the woman in two weeks to check the clinical
progress, test results and compliance with treatment of
double dose of iron (1 tablet twice a day) for 6 months
postpartum.
11. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
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12. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
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13. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
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Counselling – Diet & Rest
Reassure the mother that she can eat normal food ; these will not
harm the breast fed baby
Diet to be rich in iron & fibre
Discuss about food taboos especially against food that are
nutritionally healthy
Talk to family members like mother in law , husband to encourage
them to ensure that the woman easts enough & avoids heavy
physical work
Take care of the mother so that she can take care of the baby
Counselling on diet especially for adolescent mother
IFA Supplementation
Women with normal Hb are advised to take 1 IFA tablet daily for 3
months
If Hb below 11 gm%, advise her to take 2 IFA tabs daily and repeat
Hb after 1 month
Family support specially for girl child
Rest to the Mother
15. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
16
Screening and prophylaxis of malaria during
pregnancy
No prophylaxis is recommended but
insecticide treated bed nets/LLIN be given on
priority basis to the all pregnant women in
vulnerable population
High malaria endemic areas: Routine testing
& screening for malaria on the 1st ANC & in
each month by RDK tests even if she does not
manifest any malaria symptoms
Non endemic areas: All clinical suspected
cases (as per NVBDCP guidelines) should
preferably be investigated for malaria by RDK
17. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
18
Treatment: Uncomplicated Malaria
P. vivax
Chloroquine base to be
given as under:
Day 1 4 tabs @10mg/kg
Day 2 4 tabs @10mg/kg
Day 3 2 tabs@5 mg/kg
P. falciparum
Quinine (as tablets) 10
mg. quinine salt/kg. body
weight 3 times daily for 7
days.
18. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
19
Treatment: Severe and complicated malaria
Parenteral Quinine is the drug of choice in first trimester
Loading dose :
• 20 mg/kg. body weight on admission (I.V. infusion in 5% Dextrose/
dextrose saline over a period of 4 hours)
• May not be given if the patient has already received quinine or if clinician
feels inappropriate.
Maintenance dose:
• 10 mg./kg. bw 8 hourly
• infusion rate should not exceed 5 mg salt/kg bw per hour
NEVER give bolus injection of Quinine
Parenteral Quinine given for minimum of 48 hours & once the patient
tolerates oral therapy, follow-up treatment is as under:
• Quinine 10 mg./kg. bw three times a day to complete a course of 7 days
PLUS
• Clindamycin 10mg./kg. bw 12 hrly should be given for 7 days
If Parenteral Quinine to be given after 48 hours, reduce dose to 7 mg/kg
body weight 8 hourly.
Parenteral Treatment should be given for a minimum of 24 hours once
started
If Quinine unavailable, artemisin derivatives may be used
20. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
21
TREATMENT:
P. vivax
Chloroquine base to be
given as under:
Day 1 4 tabs @10mg/kg
Day 2 4 tabs @10mg/kg
Day 3 2 tabs@5 mg/kg
P. falciparum
ACT to be given as
under:
1st
day
2nd
day
3rd
day
AS 4 tabs 4 tabs 4 tabs
SP 3 tabs Nil Nil
AS- artesunate 50 mg
SP-Sulfadoxine 500 mg +
Pyrimethamine 25 mg
21. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
22
Treatment: Severe and complicated malaria
Parenteral artemisin derivatives preferred in 2nd
& 3rd
trimesters.
To be given as under:
• Artesunate
2.4 mg/kg bw iv or im given on admission then at 12
hours & 24 hours, then once a day
Care should be taken to dilute artesunate powder in 5%
Sodium bicarbonate provided in the pack
• Artemether
3.2 mg/kg body weight im given on admission then 1.6
mg/kg bw per day
• Α-βArteether
150 mg daily im for 3 days
22. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
23
Side effects of Quinine
Metallic taste
Nausea
Tinnitus
Hypoglycaemia
Note:
Pregnant women should not take quinine on an
empty stomach and should eat regularly, while on
quinine treatment
No special diet is needed
Primaquine is contraindicated during pregnancy.
23. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
24
Key Messages
Prophylaxis of anaemia
Management of Anaemia
Management of Complicated and
Uncomplicated Anaemia in First, Second &
Third Trimesters
Referral of Severe Anaemia Cases
24. ANAEMIA DURING PREGNANCY AND IN THE POSTPARTUM PERIOD
Maternal Health Division
Ministry of Health & Family Welfare
Government of India
25
Case Studies
Case Study Number 23 on page number 88 &
89 of Trainees Hands Book