Dr. Barry Sears discusses inflammation and its direct relationship to concussions. His labs have developed a test for the detection of inflammation and related symptoms of concussion

1. Rebuilding Damaged Brains: Implications for A Better Life

9. Typical AA/EPA Ratios 1.5 Japanese 15 Americans 20 Depression 25 ADHD 40 Brain Trauma

15. My Early Days with Dr. Dan Amen

18. ADHD Improvement Is Correlated with AA/EPA p =.007 Sorgi et al Nutrition J 6:16 (2007)

19. SPECT Scan 12-09

26. Medical Miracle or High-Dose Fish Oil?

27. Results to Date 26 M WV Coal miner CO Coma Recovered 40 M TX Firefighter CO Coma Recovered 12 M NY Baseball player Commotio cordis Coma Cardiac arrest Recovered 40 M KY Firefighter CO Coma Recovered 29 M WV Logger CHI Coma Recovered 43 F NY Childbirth Anoxia Coma Recovered 55 F FL Stroke Ischemia Coma Recovered

30. Other Neurological Conditions Treated By High-Dose Fish Oil

32. Multiple Sclerosis Disability Can Be Reversed AA/EPA Disability Status 6 2.2 1.5 1.6* Start 2 Year * p < 0.005 Nordvik et al Acta Neurol Scand 102:143 (2000)

33. My Most Well Known Parkinson’s Patient

34. Animal Studies

36. Omega-3 Blood Levels % Change in omega 3 levels from baseline Miles et al. J Neurosurgery 114: 77 (2011)

37. AA/EPA Ratio % Change in AA/EPA ratio from baseline Miles et al. J Neurosurgery 114: 77 (2011)

38. Amyloid Precursor Protein Accumulation in retraction bulbs of morphologically injured axons

39. Immunohistochemistry Animals subjected to impact acceleration injury demonstrate APP positive axons with retraction bulb morphology at 30 days

40. Immunohistochemistry Animals subjected to impact acceleration injury and supplemented with 40 mg/kg/day EPA:DHA demonstrate fewer APP positive axons with retraction bulb morphology at 30 days

41. APP positive axons Axons per high power field

42. Chronic Disease – What’s Below the Surface Autoimmune Cancer Heart disease Aging Neurological Cellular Inflammation