This BCC Research report, Sample Preparation in Genomics, Proteomics, and Epigenomics: Global Markets, provides an overview of the current overall state of the sample preparation industry for life science research focusing on the genomics, epigenomics, and proteomics segments. It describes existing products on the market, and a detailed analysis of the competitive environments, including new potential markets for novel products and assay development. This study includes information about significant players, trends, and obstacles and other information affecting this market and its different segments.
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1. Sample Preparation in Genomics, Proteomics, and Epigenomics: Global Markets
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Genomics, Proteomics, and Epigenomics: Global Markets’’ to its store.
STUDY GOALS AND OBJECTIVES
This BCC Research report, Sample Preparation in Genomics, Proteomics, and Epigenomics:
Global Markets, provides an overview of the current overall state of the sample preparation
industry for life science research focusing on the genomics, epigenomics, and proteomics
segments. It describes existing products on the market, and a detailed analysis of the
competitive environments, including new potential markets for novel products and assay
development. This study includes information about significant players, trends, and
obstacles and other information affecting this market and its different segments.
REASONS FOR DOING THIs STUDY
Experimental procedure and technical protocols are the basis for a successful scientific
project. Sample preparation steps are often the main “bottleneck” or foundation for further
downstream analysis and workflow.
Reagents companies started to recognize commercial potential in providing the required
reagents, kits, and assays that help to facilitate scientific work by reducing time, labor, and
even costs. Slowly, sample preparation products are evolving into a specific market space
with its own trends, influences, and challenges.
Although it is part of the life science reagents and tools industry in general, the sample
preparation segment exhibits specific characteristics and differences in its market
participants and competitive landscape.
This report highlights the main segments in the sample preparation industry: genomics,
proteomics, and epigenomics. It discusses its major players, current and future trends and
influences. Drivers and challenges in each segment of this industry are described in detail,
including forecasts for the next 5 years.
SCOPE AND FORMAT
This report is essentially a business tool that can help market players evaluate new
commercial opportunities in the sample preparation marketfor genomics, proteomics, and
epigenomics research. The geographic scope of this study is global. This market is complex
and consists of many different segments, each of which is affected differently by scientific
and technological developments. This report identifies the main positive and negative
factors affecting each segment, and forecasts market growth, future trends, and product
and assay development in every major segment of this market.
METHODOLOGY AND INFORMATION SOURCES
Both primary and secondary research methodologies were used in preparing this study.
Initially, a comprehensive and exhaustive search of the literature on drug discovery and
already marketed products was conducted. These secondary sources included drug
discovery and science-related journals, textbooks, press releases, marketing literature,
other product/promotional literature, annual reports, security analyst reports, and other
publications. A patent search and analysis were also conducted.
2. In a second phase, a series of semi-structured interviews was conducted with company
representatives, bench scientists, marketing representatives, and other personnel at
biotechnology and pharmaceutical companies. Other sources included academics,
technology, and consulting companies. Subsequent analysis of the documents and
interviews notes was iterative.
INTENDED AUDIENCE
This report is intended for business development professionals, entrepreneurs, and other
investors who need to fully understand and properly evaluate each segment of the market
for sample preparation in genomics, proteomics, and epigenomics research. It provides
insights into the market positions of major companies, and shows new opportunities
otherwise overlooked or less known to the business community.
ANALYST CREDENTIALS
Dr. Marianna Tcherpakov has more than 7 years experience as a bench scientist specializing
in biochemistry, cell biology, and industrial assay development. She has contributed to a
number of scientific publications and holds several patents. She has expertise as an assay
development scientist and is familiar with different research field trends and likely future
developments.
Table Of Contents
Chapter- 1: INTRODUCTION – Complimentary
STUDY GOALS AND OBJECTIVES
REASONS FOR DOING THIS STUDY
SCOPE AND FORMAT
METHODOLOGY AND INFORMATION SOURCES
INTENDED AUDIENCE
ANALYST CREDENTIALS
RELATED REPORTS
BCC ONLINE SERVICES
DISCLAIMER
Chapter- 2: SUMMARY
Table 0 : GLOBAL MARKET FOR SAMPLE PREPARATION REAGENTS AND PRODUCTS
USED IN LIFE SCIENCE RESEARCH BY SEGMENT, THROUGH 2016
Figure 0 : GLOBAL MARKET FOR SAMPLE PREPARATION REAGENTS AND PRODUCTS
USED IN LIFE SCIENCE RESEARCH BY SEGMENT, 2009–2016
Chapter- 3: INTRODUCTION TO THE SAMPLE PREP MARKET
OVERVIEW
MAJOR TRENDS AND DRIVERS IN THE SAMPLE PREP SEGMENT OF LIFE SCIENCE TOOLS
INDUSTRY
MAIN MARKET PARTICIPANTS IN THE SAMPLE PREP INDUSTRY
GEOGRAPHIC DISTRIBUTION OF THE SAMPLE PREP MARKET
TECHNOLOGY PATENTS IN THE SAMPLE PREP INDUSTRY
3. Chapter- 4: SAMPLE PREPARATION PRODUCTS FOR GENOMICS RESEARCH
OVERVIEW
GENOMICS STUDIES AS A MARKET FOR THE LIFE SCIENCE TOOLS AND SAMPLE
PREPARATION INDUSTRIES
SAMPLE PREPARATION FOR DNA AMPLIFICATION AND POLYMERASE CHAIN REACTION
SAMPLE PREPARATION MARKET FOR SEQUENCING APPLICATIONS
SAMPLE PREPARATION PRODUCTS FOR CLONING AND DNA ASSEMBLY
ADDITIONAL TARGET SUB-MARKETS FOR SAMPLE PREPARATION PRODUCTS FOR
GENOMICS
Chapter- 5: SAMPLE PREP PRODUCTS FOR EPIGENOMICS
OVERVIEW
Table 28 : GLOBAL MARKET FOR DRUG DISCOVERY IN EPIGENOMIC RESEARCH,
2011–2016
Chapter- 6: PROTEOMICS RESEARCH AS A MARKET FOR THE SAMPLE
PREPARATION INDUSTRY
OVERVIEW
Table 34 : GLOBAL MARKET FOR PROTEOMICS TOOLS, THROUGH 2016
Chapter- 7: LABELING AND PROBES IN THE SAMPLE PREP MARKET
OVERVIEW
LABELING
LABELING AND PROBES FOR GENOMICS STUDIES
LABELING AND PROBES FOR PROTEOMICS STUDIES
Chapter- 8: SAMPLE PREPARATION FOR THE CELL BIOLOGY REAGENTS MARKET
OVERVIEW
Table 49 : GLOBAL MARKET FOR CELL BIOLOGY REAGENTS, THROUGH 2016
Table 50 : GLOBAL MARKET SHARES OF CELL BIOLOGY REAGENTS BY PRODUCT
CATEGORY
Chapter- 9: GLOBAL TARGET MARKETS FOR SAMPLE PREPARATION BY
APPLICATION
OVERVIEW
FOOD SAFETY TESTING
ANIMAL HEALTH DIAGNOSTICS
FORENSICS AS A TARGET MARKET FOR THE SAMPLE PREPARATION INDUSTRY
BIODEFENSE AS A DRIVER MARKET FOR THE SAMPLE PREPARATION INDUSTRY
Table 57 : HEALTH AND HUMAN SERVICES DEPARTMENTAL BUDGETS, 2010
Chapter- 10: MARKET SUMMARY
OVERVIEW
MARKET PARTICIPANTS
Table 62 : MAIN MARKET PARTICIPANTS IN THE SAMPLE PREPARATION
INDUSTRY FOR LIFE SCIENCE RESEARCH
Chapter- 11: SELECTED PROFILES OF COMPANIES
PROFILES
LIST OF COMPANIES
4. List of Tables
Summary Table : GLOBAL MARKET FOR SAMPLE PREPARATION REAGENTS AND PRODUCTS
USED IN LIFE SCIENCE RESEARCH BY SEGMENT, THROUGH 2016
Table 1 : GLOBAL MARKET FOR COMMON REAGENTS AND PRODUCTS IN THE LIFE SCIENCE
TOOLS INDUSTRY BY SEGMENT, THROUGH 2016
Table 2 : GLOBAL MARKET SHARES OF THE SAMPLE PREP INDUSTRY BY LIFE SCIENCE
RESEARCH SEGMENT, 2011
Table 3 : GLOBAL MARKET SHARES OF THE SAMPLE PREP INDUSTRY BY GEOGRAPHIC
REGION, 2011
Table 4 : GLOBAL MARKET FOR GENOMICS PRODUCTS, THROUGH 2016
Table 5 : GLOBAL MARKET VALUE OF NUCLEIC ACID EXTRACTION PRODUCTS, THROUGH
2016
Table 6 : NUCLEIC ACID MARKET SHARES BY COMPANY, 2011,
Table 7 : DISTRIBUTION OF THE NUCLEIC ACID PREPARATION MARKET BY TYPE OF END
USER, 2011
Table 8 : GEOGRAPHIC DISTRIBUTION OF THE NUCLEIC ACID PREPARATION MARKET, 2011
Table 9 : GLOBAL MARKET SHARES OF RNA ISOLATION PRODUCTS BY COMPANY, 2011
Table 10 : SELECT COMPANIES PROVIDING PRODUCTS FOR FFPE NUCLEIC ACID
EXTRACTION
Table 11 : DISTRIBUTION OF AUTOMATION DEVICES FOR NUCLEIC ACID PURIFICATION BY
TYPE OF END USER, 2011
Table 12 : COMPANIES THAT PROVIDE NUCLEIC ACID SAMPLE PREPARATION PLATFORMS
Table 13 : AVERAGE PRICES OF NUCLEIC ACID PURIFICATION UNITS OFFERED BY
REPRESENTATIVE COMPANIES, 2011
Table 14 : GLOBAL DNA AMPLIFICATION/PCR MARKET, THROUGH 2016
Table 15 : GLOBAL RT-PCR MARKET SHARES BY COMPANY, 2011
Table 16 : GLOBAL PCR MAKET SHARES BY GEOGRAPHIC REGION, 2011
Table 17 : SAMPLE PREPARATION MARKET ESTIMATE FOR PCR APPLICATIONS, THROUGH
2016
Table 18 : GLOBAL MARKET FOR DNA SEQUENCING, THROUGH 2016
Table 19 : GLOBAL MARKET FOR NGS AND GENERAL SEQUENCING, THROUGH 2016
Table 20 : NGS MARKET SHARES BY COMPANY, 2011
Table 21 : CRITERIA FOR CHOOSING A SPECIFIC VENDOR FOR SAMPLE PREP IN NGS
ACCORDING TO PRIORITY
Table 22 : VALUE OF NGS FOR THE SAMPLE PREP MARKET THROUGH 2016
Table 23 : RECENT ACQUISITIONS AND COLLABORATIONS IN THE NGS SAMPLE PREP
INDUSTRY, 2011
Table 24 : MARKET ESTIMATION FOR SAMPLE PREPARATION IN MOLECULAR CLONING,
THROUGH 2011
Table 25 : GLOBAL MARKET FOR DNA MICROARRAYS, THROUGH 2016
Table 26 : SELECT RNA SYNTHESIS, DEGRADATION, AND MODIFICATION PRODUCTS
Table 27 : GLOBAL RNA INTERFERENCE MARKET THROUGH 2016
Table 28 : GLOBAL MARKET FOR DRUG DISCOVERY IN EPIGENOMIC RESEARCH, 2011–
2016
Table 29 : SELECT EPIGENOMIC PRODUCTS BY SUPPLIER
Table 30 : SELECT EPIGENOMIC SAMPLE PREPARATION PRODUCTS BY SUPPLIER
Table 31 : PERCENTAGE OF COMMERCIAL KITS GENERALLY PURCHASED FOR EPIGENOMIC
RESEARCH BY PRODUCT TYPE
5. Table 32 : GLOBAL MARKET RESEARCH TOOLS IN THE EPIGENOMIC SEGMENT, THROUGH
2016
Table 33 : DISTRIBUTION OF EPIGENOMIC PRODUCTS IN THE U.S. SAMPLE PREPARATION
INDUSTRY BY TYPE OF END USER, 2011
Table 34 : GLOBAL MARKET FOR PROTEOMICS TOOLS, THROUGH 2016
Table 35 : PERCENTAGE USE OF SPECIFIC PROTEIN EXPRESSION TECHNIQUES, 2011
Table 36 : PROTEIN EXPRESSION MARKET SHARES BY COMPANY, 2011
Table 37 : GLOBAL MARKET FOR PROTEIN CHROMATOGRAPHY, THROUGH 2016
Table 38 : AVERAGE SPENDING PER SCIENTIST ON PURIFICATION/SEPARATION PRODUCTS
Table 39 : GLOBAL MARKET FOR MASS SPECTROMETRY, THROUGH 2016
Table 40 : PERCENTAGE OF TOTAL NMR APPLICATIONS IN VARIOUS SECTORS, 2011
Table 41 : GLOBAL MARKET FOR 2D GEL ANALYSIS, THROUGH 2016
Table 42 : EXAMPLES OF 2D GEL SAMPLE PREPARATION PRODUCTS BY COMPANY, 2011
Table 43 : GLOBAL PROTEIN CHIP MARKET, THROUGH 2016
Table 44 : MARKET ESTIMATE FOR SAMPLE PREPARATION PRODUCTS IN PROTEOMICS,
THROUGH 2011
Table 45 : CATEGORIES IN THE SAMPLE PREPARATION MARKET FOR PROTEOMICS
RESEARCH AND EXAMPLES OF MARKET PARTICIPANTS
Table 46 : EXAMPLES OF SAMPLE PREPARATION SERVICES FOR PROTEOMICS RESEARCH
AND THEIR AVERAGE COST
Table 47 : DISTRIBUTION OF THE PROTEOMICS SAMPLE PREPARATION MARKET BY TYPE
OF END USER, 2011
Table 48 : GLOBAL MARKET FOR VARIOUS LABELING AND PROBES, 2011
Table 49 : GLOBAL MARKET FOR CELL BIOLOGY REAGENTS, THROUGH 2016
Table 50 : GLOBAL MARKET SHARES OF CELL BIOLOGY REAGENTS BY PRODUCT CATEGORY
Table 51 : GLOBAL MARKET FOR FLOW CYTOMETRY, THROUGH 2016
Table 52 : U.S. MARKET FOR STEM CELL RESEARCH TOOLS, THROUGH 2016
Table 53 : REPRESENTATIVE PRICING FOR SAMPLE PREPARATION SERVICES IN CELL
BIOLOGY
Table 54 : MARKET VALUE OF FOOD SAFETY TESTING FOR PATHOGENS IN THE U.S.
THROUGH 2016
Table 55 : GLOBAL MARKET VALUE OF ANIMAL HEALTH TESTING, THROUGH 2016
Table 56 : U.S. MARKET FOR DNA TESTING SERVICES AND PRODUCTS IN THE FORENSICS
INDUSTRY, 2010
Table 57 : HEALTH AND HUMAN SERVICES DEPARTMENTAL BUDGETS, 2010
Table 58 : MARKET ESTIMATE FOR SAMPLE PREPARATION PRODUCTS IN GENOMICS,
THROUGH 2016
Table 59 : MARKET ESTIMATE FOR SAMPLE PREPARATION PRODUCTS IN EPIGENOMICS,
THROUGH 2016
Table 60 : MARKET ESTIMATE FOR SAMPLE PREPARATION PRODUCTS IN PROTEOMICS,
THROUGH 2016
Table 61 : MARKET SHARE OF GENOMICS VS. PROTEOMICS SAMPLE PREP PRODUCTS BY
TYPE OF END USER, 2011
Table 62 : MAIN MARKET PARTICIPANTS IN THE SAMPLE PREPARATION INDUSTRY FOR
LIFE SCIENCE RESEARCH
List of Figures
Summary Figure : GLOBAL MARKET FOR SAMPLE PREPARATION REAGENTS AND PRODUCTS
USED IN LIFE SCIENCE RESEARCH BY SEGMENT, 2009–2016
6. Figure 1 : GENOME AND GENE ANALYSIS WORKFLOW
Figure 2 : PROTEIN ANALYSIS WORKFLOW
Figure 3 : MARKET ESTIMATE FOR SAMPLE PREPARATION PRODUCTS IN GENOMICS, 2009–
2016
Figure 4 : MARKET ESTIMATE FOR SAMPLE PREPARATION PRODUCTS IN EPIGENOMICS,
2009–2016
Figure 5 : MARKET ESTIMATE FOR SAMPLE PREPARATION PRODUCTS IN PROTEOMICS,
2009–2016
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