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Proceeding with Caution:
“Rethinking the ADHD Diagnosis”
           Presented By:
        Luke Ibach and Josh Kakar
               April 1, 2009
             Psychology 493
Video Clip
http://www.youtube.com/watch?v=SzdGrUcc bQ
Proponents of the ADHD Diagnosis
• Joseph Biederman - a Harvard child
  psychiatrist who believes that ADHD is real.
  Says 8-12% of all American children have the
  disease.
Proponents of the ADHD Diagnosis
• Russell Barkley - a research professor at SUNY
  Upstate Medical University in Syracuse. He
  reports that in a classroom with 30 students 1
  in 3 will have ADHD.
Refuting their ideas
• On the contrary, NIH reports that only about 3-5
  % of all American school children have been
  diagnosed with ADHD, which is considerably
  lower then Biederman’s 8-12% statistic.
• Biederman is also being investigated for failing to
  report almost 1.6 million dollars for consulting
  fees from drug makers.
• In one case Biederman falsely reported only
  receiving 3,500 dollars from Johnson & Johnson
  when he actually received over 58,000 dollars in
  grant money.
Critics of ADHD
• Thomas Armstrong - Argues that there is no
  definitive criteria to determine who has ADHD
  and who doesn’t. He also believes behaviors
  that test for ADHD are highly context
  dependent.
Critics of ADHD
• Peter Breggin – is a Harvard graduate who
  believes that stimulants are not the answer
  for ADHD. He claims that there is are no
  scientific studies that validate ADHD.
Growth of ADHD Epidemic
•   1970- 150,000 school children diagnosed
•   1985- 500,00
•   1990- 1,000,000
•   2000- 6,000,000

• Possible reasons for such a dramatic increase
ADHD Medicating Our Kids
• 8.3 million stimulant tablets prescribed in
  1984.
• 38.4 million stimulant tablets prescribed in
  2001.
• 56% of children that were diagnosed with
  ADHD were prescribed medication on the first
  Dr’s visit.
ADHD Statistics
• Boys are diagnosed with ADHD 3 times more
  often then girls.
• 1/3rd of children diagnosed with ADHD are
  also diagnosed with ODD.
• 1/4th of children with ADHD are diagnosed
  with CD.
• Overall about 1/3rd of children that have
  ADHD are also diagnosed with another
  disorder.
Introduction: What is ADHD?
DSM-IV Criteria: (A) Inattention or (B) Hyperactivity-
  Impulsivity
• (A) Inattention: Six or more of the symptoms of
  inattention have been present for at least 6 months to a
  point that is disruptive and inappropriate for
  developmental level:
   – Often does not give close attention to details or
     makes careless mistakes in schoolwork, work, or other
     activities.
   – Often has trouble keeping attention on tasks or play
     activities.
   – Often does not seem to listen when spoken to directly.
   – Often does not follow instructions and fails to finish
     schoolwork, chores, or duties in the workplace.
Introduction: What is ADHD?
(Continued)
   – Often has trouble organizing activities.
   – Often avoids, dislikes, or doesn't want to do things that
      take a lot of mental effort for a long period of time.
   – Often loses things needed for tasks and activities (e.g.
      toys, school assignments, pencils, books, or tools).
   – Is often easily distracted.
   – Is often forgetful in daily activities.
Introduction: What is ADHD?
• (B)Hyperactivity-Impulsivity: Six or more of the following
  symptoms of hyperactivity-impulsivity have been present
  for at least 6 months to an extent that is disruptive and
  inappropriate for developmental level:
   – Often fidgets with hands or feet or squirms in seat.
   – Often gets up from seat when remaining in seat is
     expected.
   – Often runs about or climbs when and where it is not
     appropriate.
   – Often has trouble playing or enjoying leisure activities
     quietly.
   – Is often quot;on the goquot; or often acts as if quot;driven by a motorquot;.
   – Often talks excessively.
Introduction: What is ADHD?
• (B)Impulsivity (Continued)
   – Often blurts out answers before questions have been
      finished.
   – Often has trouble waiting one's turn.
   – Often interrupts or intrudes on others.
   – Some symptoms that cause impairment were present
      before age 7.
   – Some impairment from the symptoms is present in two or
      more settings (e.g. at school/work and at home).
   – Must be clear evidence of significant impairment in
      social, school, or work functioning.
   – The symptoms are not better accounted for by another
      mental disorder.
What is ADHD?
• ADHD, Combined Type: if both criteria 1A and
  1B are met for the past 6 months
• ADHD, Predominantly Inattentive Type: if
  criterion 1A is met but criterion 1B is not met
  for the past six months
• ADHD, Predominantly Hyperactive-Impulsive
  Type: if Criterion 1B is met but Criterion 1A is
  not met for the past six months.
Criticisms of the ADHD Diagnosis:
      Reliability of Diagnosis
– Research shows low interater reliability of ADHD
  symptoms across countries, cultures, and even
  within cultures (Timimi et. al. , 2004)
– Specifically, rates vary by a factor of 10 from
  county to county within individual states in the
  U.S.
– A U.S. study showed that teachers rated 49% of
  boys as restless, 43% having short attention span
  and 43% as inattentive during conversations.
Criticisms of the ADHD Diagnosis:
      Reliability of Diagnosis
– An England Epidemiological study diagnosed only
  two children out of 2,199 with hyperactivity(.09%)
  (Armstrong, 1996).
– In contrast, a study in Israel found that teachers
  rated 28% of students as hyperactive
– 80% of patients diagnosed do not show symptoms
  in the physician’s office(Armstrong, 1996).
– Prevalence Estimates range between 1 – 20%
Criticisms of the ADHD Diagnosis:
 Subjective Ratings of Behavior
– The most common assessment includes a
  checklist of behavior and scales for the
  frequency of the behavior exhibited.
Ex: Scale rating of 1 – 5
(1 = almost never) and (5 = almost always)
Items: “Restless(squirms in seat)”, “Fidgety(hands
  always busy)”, “Follow a sequence of
  instructions”
Iowa Connor’s Teacher Rating Scale
Criticisms of the ADHD Diagnosis:
    Subjective Ratings of Behavior
• Children are rated by teachers and parents who have
  subjective biases, standards and expectations about
  their behavior.
• These authority figures may have a proclivity towards
  the ADHD diagnoses in order to keep children
  compliant in either the home or school setting, as a
  result of medication or special education placement.
Criticisms of the ADHD Diagnosis:
     Subjective Ratings of Behavior
• These subjective measures of behavior are limited in
  scope considering they do not take into account the
  context or environment in which the child is
  currently in during time of assessment
• A child may be a 5(almost always) on fidgetiness in
  one situation ( i.e. during school work) but a 1 at
  during more stimulating activities (i.e. recess, play
  time)
• Therefore, assigning one number for all contexts and
  environments is not fully representative of a child’s
  true behavior.
Criticisms of the ADHD Diagnosis:
     Subjective Ratings of Behavior
• One study compared ratings of parents, teachers, and
  physicians for 5,000 elementary children.
• 5% were considered hyperactive by one of the groups
  but only 1% were rated hyperactive by all 3 groups of
  raters.
• Another study revealed that agreement between
  mothers and fathers on their child’s diagnosis of
  hyperactivity was only 32%
• The study also showed that rating agreement between
  parents and teachers was even lower, at 13%.
Criticisms of the ADHD Diagnosis:
    Subjective Ratings of Behavior
• What is considered normal behavior in children?
• Many normal children have problems with
  fidgetiness and attention. So where do we draw
  the line?
• What about children at the other end of the
  spectrum, who are too compliant, and too
  focused? This issue is rarely addressed.
• These evaluations are purely subjective, prone to
  error and bias, and not objective in their design.
Criticisms:
     Objective Ratings of Behavior
• (CPTs) – Continuous Performance Tasks –
  Measure patient’s selective attention to the
  presence or absence of stimuli during sets of
  distracters.
• Ex: (GDS) – Gordon Diagnostic System –
  Patients press a button after specific sets of
  ordered digits have been flashed up on a
  computer screen. The number of correct
  responses and incorrect responses are
  recorded as “hits” and “ misses” respectively.
Criticisms of the ADHD Diagnosis:
    Objective Ratings of Behavior
• These tests of vigilance were developed to select
  promising candidates for radar operations during
  World War II.
• Although CPTs intend to present an objective
  measure of children’s selective attention, they
  only tell how the child will perform on
  repetitive, mundane, and non-stimulating tasks
  irrelevant to what children encounter in their real
  lives.
• Therefore, the validity of their current use with
  children today should be questioned.
Criticisms of the ADHD Diagnosis:
            Temperament
– Symptoms do not significantly differ from children who
  have normal variations in temperament (Carey, 1998).
– This is especially true when children are given the chance
  to choose their own learning activities and perform at
  their own pace. (Armstrong, 1996).
– Children with ADHD behave normally when exposed to
  interesting, novel, or stimulating tasks.
– 70% of children diagnosed find ADHD symptoms
  disappear upon reaching adulthood.
– Temperament research shows only about 50% of most
  populations sampled are attentive with the other 50%
  displaying below average attentiveness.
Criticisms of the ADHD Diagnosis:
              Temperament
• Currently, there is no supporting evidence for
  arbitrary cut off scores for abnormal levels of high
  activity and attentiveness (Levy, Hay, Mcstephen, et.
  Al., 1997).
• Although children with difficult temperament (low
  adaptability , negative mood) and low task
  orientation (high energy, low persistence-attention
  span, high distractibility) experience more social
  problems and poor academic achievement
  respectively, these traits do not lead to dysfunction
  on their own, but only when other environmental
  problems occur as well.
Criticisms:
                    Co-morbidity
• Co-existing conditions with ADHD include:
   –   Problems with parent-child interaction
   –   Family violence
   –   Parental Psychopathology
   –   Anxiety Disorder – (25-34%)
   –   Bipolar disorder - (18-60%)
   –   Depression – (18-60%)
   –   Learning disabilities – (12-60%)
   –   Conduct Disorder - (35-60%)
   –   Oppositional Defiant Disorder – (35-60%)
Co-morbidity
• According to Pliszka (2000) most children who
  meet the criteria for conduct disorder or
  oppositional defiant disorder will also meet the
  criteria for ADHD.
• Although medication is claimed to successfully
  treat all 3 conditions, Children with Conduct
  Disorder require additional intervention when
  there is also family psychopathology present.
• This raises an obvious question if ADHD is an
  adequate diagnostic category to explain the
  child’s functioning in other domains in life.
Co-morbidity
• Learning disabilities can cause inattention and
  frustration and mask the presence of
  ADHD(Furman, 2006).
• Although stimulants have been shown to
  improve reading scores, it is believed that
  these improvements are related to
  performances requiring repetition and
  concentration and not genuine learning.
Co-morbidity
• Although stimulants are used primarily to
  treat ADHD, they can be extremely harmful in
  treating co-morbid conditions such as mood
  disorders
• Stimulants used to treat depression and
  bipolar disorder can cause dysphoria and
  harmful mood dysregulation. (Furman, 2006).
• Clinicians who use stimulants to treat these
  co-morbid conditions must exercise extreme
  caution.
Co-morbidity
• According to evidence-based
  perspectives, Cognitive-Behavioral Therapy is the
  best known treatment modality for children with
  anxiety and ADHD.
• In addition, children with ADHD and anxiety
  disorder do not respond as well to stimulant
  medication.
• Unfortunately, symptoms of anxiety disorder are
  overlooked by providers and not considered
  during the assessment process as ADHD
  symptoms are probably more salient
  (Furman, 2006).
Co-morbidity
• The large amount of overlap between ADHD
  and other co-ocurring psychopathology
  provides additional support for the argument
  that ADHD is not a separate psychological or
  neurological condition.
Criticisms:
      The Disease Model Of ADHD
• ADHD is believed to be a neurodevelopmental
  brain disorder with biological predispositions and
  distinct etiology.
• Potential causes include chemical abnormalities(
  serotonin, dopamine, norepinephrine), neurologica
  l damage, lead poisoning, thyroid
  dysfunction, prenatal exposure to harmful
  substances, and delayed transmission of nerve
  impulses.
• Mechanistic view of human capacity, where the
  mind functions much like a machine.
Criticisms:
       The Disease Model Of ADHD
• Despite an emphasis on biological brain causes, no
  clear biological markers have ever been discovered in
  patients diagnosed with ADHD.
• According to Carey(1998), children with brain
  damage show no clear pattern of hyperactivity or
  inattention and children diagnosed with ADHD show
  no consistent structural, functional or neurochemical
  abnormality.
• Carey(1998) even points out that brain differences
  are present in healthy children who display variations
  in normal temperament.
The Disease Model Of ADHD
• Timimi(2002) also points out that there is no
  medical test to detect the presence of ADHD.
• Neuroimaging studies have shown no clinical
  abnormalities between the brains of children
  diagnosed with ADHD and age matched-control
  groups (Hynd & Hooper, 1995) (Baumeister and
  Hawkins, 2001).
• A Federal Government report on ADHD concluded
  that: “…there was no compelling evidence to
  support the claim that ADHD was a biochemical
  brain disorder” (National Institutes of
  Health, 1998).
The Disease Model Of ADHD
• However, many studies that claim to show biological
  evidence of ADHD have omitted important additional
  research that contradicts original findings. This
  notion is also reinforced by inaccurate media
  coverage.
• For example, a study by Zametkin et. Al, 1990 at
  NIMH found a link between reduced metabolism of
  glucose and adult hyperactivity.
• They concluded that deficits in the premotor and
  superior prefrontal cortex accounted for this
  inhibited metabolism of glucose.
The Disease Model Of ADHD
• Despite positive attention by departments of
  psychiatry and the media, an additional study
  by Zametkin et. Al, in 1993 found no
  significant differences between the brains of
  normal and hyperactive adolescents.
• This contradictory finding to the study was not
  reported by the media or the ADHD
  community.
Criticisms:
          Medication for ADHD
• Methylphenidate, dextroamphetamine, and
  methamphetamine are the most popular
  psychostimulant treatments for ADHD.
• An estimated “10-12 percent of all boys
  between the ages of 6 and 14 in the United
  States have been diagnosed as having ADHD
  and are being treated with methylphenidate.”
• Breggin(1998) estimates that 4-5 million
  children receive psychostimulants in the U.S.
  each year.
Criticisms:
           Medication for ADHD
• However, these medications produce toxicity and
  general excitation of the Central Nervous System.
• Have effects on neurotransmitters such as
  dopamine, norepinephrine, and serotonin.
• Symptoms such as increased
  energy, hyperalertness, and hyperfocus are
  reported.
• Other symptoms include
  insomnia, OCD, agitation, hypomania, mania, seiz
  ures, fatigue, lethargy, social withdrawal, and
  depression, irritability, anxiety, and emotional
  sensitivity.
Medication for ADHD
• Firestone et. al (1998), found preschool children
  ADHD who were treated with methylphenidate
  experienced greater social dampening effects when
  compared to a placebo group.
• Such sideffects included:
  – “Talks less with others” - increased from 21% to 50%
  – “Uninterested in others” – increased from 31% to 75%
  – “Sad/Unhappy” – increased 47% to 84%

  – These findings are also consistent with those of Schleifer
    et. al. (1975) who also found “less social behavior and
    interaction, and increased solitary play” in ADHD
    children treated with methylphenidate.
Medication for ADHD
• A study by Mayes and colleagues (1994) found that
  children treated with methylphenidate were
  reported as
  “withdrawn, listless, depressed, dopey, dazed, subd
  ued, and inactive”.
• This study also found that children suffered from
  somatic complaints including
  insomnia(13%), nausea or vomiting(11%), loss of
  appetite(20%), and headache(4%).
• Schachar et. al. (1997) concluded that affective
  symptoms develop in later stages of drug
  treatment are often missed in most short term
  drug studies.
Medication for ADHD
• Firestone et al. (1998) also found increases in
  nervous movements (“tics”) in children
  treated with stimulant medication, with an
  increase from 3% (placebo) to 12% in children
  on methylphenidate.
• Barkely et. al (1990) reported a 10% increase
  in abnormal movements in children treated
  with higher doses of methylphenidate.
• Borcherding et. al. found 58% of their
  medicated children demonstrated abnormal
  nervous movements, with one permanent
  case of “tics”.
Medication for ADHD
• Breggin, 1998b; Kessler, 1993; Leber, 1992 highlight
  2,821 reports of adverse reactions to
  methylphenidate in the Spontaneous Reporting
  System:
   – 1. More than 150 reports of liver abnormalities
   – 2. Sixty Nine reports of convulsions, 18 specifically grand
     mal.
   – 3. Eighty-seven reports of drug dependency, addiction
   – 4. Thirty reports of drug withdrawal
   – 5. Two hundred fifty reports of hair loss
   – 6.Fifty reports of leukopenia (low white blood cell count)
Medication for ADHD
• According to Karch (1996) several studies now show
  direct evidence that methylphenidate has cardiotoxic
  effects.
• Specifically, Henderson & Fischer (1994) studied the
  effects on mice and discovered toxic effects within 3
  weeks after using only minimum doses
• Ishiguro & Morgan (1997) found that methylphenidate
  adminstered to ferrets at levels equal to clinical usage
  produced contraction problems in the heart muscles.
• FDAs Spontaneous Reporting System found 121 reports
  of cardiovascular problems, with 9 cardiac arrests and
  4 hearts failures (Elinwood & Tong, 1996).
Medication for ADHD
• According to the American Psychiatric Association
  (1994), methylphenidate: “In clinical studies…produces
  behavioral, psychological, subjective, and reinforcing
  effects similar to d-amphetamine and cocaine.”
• “7% of Indiana high school students have used Ritalin
  non-medically at least once, and that about 2.5% of
  high school students use it on a monthly or more
  frequent basis” (Indiana Prevention Resource
  Center, 1998).
• Breggin (1998a) believes that over medicating children
  teaches them to exert less control over their actions
  and behavior.
Medication Research
• Much medication research has been
  questionable in it’s design.
• For example, the (MTA) NIMH Multimodal
  Treatment Study for ADHD had an abundance
  of errors in methodology yet claimed that
  stimulant treatment was superior to
  behavioral and community treatment.
• Peter Breggin offers a critical analysis of this
  study and points out many of it’s limitations
Medication Research
• 1. The MTA was not a placebo controlled, double
  blind clinical trial.
   – Investigators relied on ratings made by teachers and
     parents who were not blind to the treatment - “Open label
     studies” which are often discredited.
• 2. The study used no control group of untreated
  children.
   – The study only compared 3 drug conditions to behavioral
     treatments
• 3. Thirty-two percent of the Medication
  Management group was already taking medication
  before hand.
   – Created unequal participants for the study due to history
Medication Research
• 4. Blind classroom raters observed no
  difference between treatment groups
  – Although medication did not demonstrate any
    superior benefits behavioral treatments, this
    finding was withheld from the studies’
    conclusions
• 5. Drug treatments exceeded behavioral
  treatments in length of duration.
  – This bias could appear to make medication a more
    effective treatment then behavioral treatments
Medication Research
• 6. Children in the drug treatment group did not
  rate themselves as feeling improved.
   – This important finding was also omitted from the
     study’s conclusions as well
• 7. All of the principal investigators were well
  known drug advocates
   – Received funding from Richwood, Bristol-
     Myers, Solvay, Wyeth-Ayerst, Glaxo, and Eli Lilly
• 8. Parents and teachers were exposed to drug
  propaganda.
   – Parents were told their children would be treated with
     “safe effective doses of medication”
Overlooked Factors:
                Nutrition
• A nutrition approach takes longer to show
  results. “With dietary supplements you can
  see improvement in behavior in a week or
  two,” says Zimmerman. “A food approach is
  more of a long-term thing—a 30-day plan, for
  example.”
George Washington University
• A study by George Washington University
  found that hyperactive children who ate a
  meal high in protein did equally well or
  sometimes even better in school then non
  hyperactive kids
Fatty acids
• What are they?

What are some examples?

Where do you get them from?
Oxford University
• Oxford University found that the ADHD
  symptoms in children receiving essential fatty
  acids improved over children in a control
  group receiving a placebo
Overlooked Factors:
                Nutrition
• Researchers further documented the essential
  fatty acid deficiency tie to Attention Deficit
  Disorder in a 1987 study. Then, a 1995 study
  comparing essential fatty acid levels in ADHD
  boys against a control group of boys without
  ADHD found significantly lower levels of
  Omega-3 fatty acids.
Overlooked Factors:
                Nutrition
• In 1996 Purdue University researchers have
  found that boys with low blood levels of
  Omega-3 fatty acids have a greater frequency
  of Attention Deficit Disorder ADHD.
Food Coloring
• Study done by South Hampton University in
  UK

• EFSA’s advice given to ADHD parents

• Types of food coloring used
Overlooked Factors:
             American Culture
• Change in the cultural expectations of children
  – Children now are expected to behave in ways that
    are not always developmentally appropriate
  – Many view these high expectations as an end to
    childhood innocence, coupled with the fact that
    children are constantly exposed to adult
    information via media and television (Postman
    1983).
  – Children are now seen as a danger to society and
    need to be controlled, reshaped and changed.
Overlooked Factors:
             American Culture
• With more anxiety in place regarding
  childrearing, but also fear of state intervention
  in domestic affairs, ADHD offers a shift away
  from social dilemmas and onto the child.
  (Timimi, 2002).
• Parents feel economic pressures to work long
  hours leaving medication the most convenient
  “quick fix” treatment for ADHD and less time
  for family therapy approaches involving
  parent-child interaction (Furman, 2006).
Overlooked Factors:
             American Schools
• Public school system curriculums are tailored
  mainly towards academics such as
  reading, writing, arithmetic, and standardized
  testing, and leave less emphasis on creative
  and engaging activities.
• Thus, students who do no excel in these areas
  but in others such as the arts, physical
  activities, or hands-on kinesthetic learning are
  not in an environment that is conducive to
  their style of learning
Overlooked Factors:
             American Schools
• Therefore these students fall through the
  cracks and receive less assistance for their
  special needs of learning and are viewed as
  having a biological brain disorder.
Overlooked Factors:
         Alternative Treatment
• According to Breggin (2000), ADHD can be
  treated through means other than medication
  such as individualized family counseling and
  educational approaches to empower
  children, parents teachers and others.
Overlooked Factors:
          Alternative Treatment
• Applied behavior analysis is an overlooked yet
  effective method for improving behavior in
  school.
• According to Packard (1970), classroom
  attention can be achieved and maintained in
  students when teacher instruction is coupled
  with group contingencies.
• For example, in Packard’s (1970) study, the
  instructor turned on a red light-timer device
  whenever a student was not paying attention.
Overlooked Factors:
          Alternative Treatment
• When all students showed proper attention, the
  teacher turned off the device.
• Classrooms were rewarded with play activities
  upon maintenance of attention and teachers gave
  verbal feedback as to what percentage of the
  class paid attention. All students achieved 90-
  100% levels of classroom attention.
• Therefore, Packard (1970) concluded that it is
  possible to motivate students to pay attention
  when an appropriate and appealing reward
  system is implemented.
Improving the ADHD Epidemic
            (Carey) 2005
• 1. Improved diagnostic system - Distinctions must
  be made between hyperkinetic children, who are
  truly pervasively overactive or inattentive, and
  those primarily having other problems
• 2. Better research - Much is still unknown about the
  origin of ADHD and additional research is needed
  to adequately conceptualize and treat what
  appears not to be a biologically based psychological
  disorder.
Improving the ADHD Epidemic
             (Carey) 2005
• 3. More education of professionals and public –
  People need more information about important
  matters such as normal variations in
  temperament and the non-specificity and
  harmful side effects of stimulant medications.
• 4. Better evaluations – Children should undergo
  educational testing to rule out learning
  disabilities as the main cause of their behavior
  and also examine the child’s temperament and
  adjustment.
Improving the ADHD Epidemic
             (Carey) 2005
• 5. Improved treatment – Greater reliance on
  psychosocial and educational interventions.
  Treatments should also be geared to build on
  the child’s strengths and remediate their
  weaknesses.
• 6. Close monitoring of drug company
  advertising and promotion
• 7. Regulation of both medical diagnosis and
  teacher insistence on medication.
Conclusion
• ADHD should be questioned until more sound
  scientific evidence becomes available to
  consider it a distinct neurological condition.
• Parents and practitioners should remain
  skeptical of the disorder and be cautioned
  against a quick assignment to the ADHD
  diagnosis.
• The risks of medication and stigmatization are
  too harmful to unique children who hold so
  much potential.
The End
Thank you for watching.

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Adhd Presentation

  • 1. Proceeding with Caution: “Rethinking the ADHD Diagnosis” Presented By: Luke Ibach and Josh Kakar April 1, 2009 Psychology 493
  • 3. Proponents of the ADHD Diagnosis • Joseph Biederman - a Harvard child psychiatrist who believes that ADHD is real. Says 8-12% of all American children have the disease.
  • 4. Proponents of the ADHD Diagnosis • Russell Barkley - a research professor at SUNY Upstate Medical University in Syracuse. He reports that in a classroom with 30 students 1 in 3 will have ADHD.
  • 5. Refuting their ideas • On the contrary, NIH reports that only about 3-5 % of all American school children have been diagnosed with ADHD, which is considerably lower then Biederman’s 8-12% statistic. • Biederman is also being investigated for failing to report almost 1.6 million dollars for consulting fees from drug makers. • In one case Biederman falsely reported only receiving 3,500 dollars from Johnson & Johnson when he actually received over 58,000 dollars in grant money.
  • 6. Critics of ADHD • Thomas Armstrong - Argues that there is no definitive criteria to determine who has ADHD and who doesn’t. He also believes behaviors that test for ADHD are highly context dependent.
  • 7. Critics of ADHD • Peter Breggin – is a Harvard graduate who believes that stimulants are not the answer for ADHD. He claims that there is are no scientific studies that validate ADHD.
  • 8. Growth of ADHD Epidemic • 1970- 150,000 school children diagnosed • 1985- 500,00 • 1990- 1,000,000 • 2000- 6,000,000 • Possible reasons for such a dramatic increase
  • 9. ADHD Medicating Our Kids • 8.3 million stimulant tablets prescribed in 1984. • 38.4 million stimulant tablets prescribed in 2001. • 56% of children that were diagnosed with ADHD were prescribed medication on the first Dr’s visit.
  • 10. ADHD Statistics • Boys are diagnosed with ADHD 3 times more often then girls. • 1/3rd of children diagnosed with ADHD are also diagnosed with ODD. • 1/4th of children with ADHD are diagnosed with CD. • Overall about 1/3rd of children that have ADHD are also diagnosed with another disorder.
  • 11. Introduction: What is ADHD? DSM-IV Criteria: (A) Inattention or (B) Hyperactivity- Impulsivity • (A) Inattention: Six or more of the symptoms of inattention have been present for at least 6 months to a point that is disruptive and inappropriate for developmental level: – Often does not give close attention to details or makes careless mistakes in schoolwork, work, or other activities. – Often has trouble keeping attention on tasks or play activities. – Often does not seem to listen when spoken to directly. – Often does not follow instructions and fails to finish schoolwork, chores, or duties in the workplace.
  • 12. Introduction: What is ADHD? (Continued) – Often has trouble organizing activities. – Often avoids, dislikes, or doesn't want to do things that take a lot of mental effort for a long period of time. – Often loses things needed for tasks and activities (e.g. toys, school assignments, pencils, books, or tools). – Is often easily distracted. – Is often forgetful in daily activities.
  • 13. Introduction: What is ADHD? • (B)Hyperactivity-Impulsivity: Six or more of the following symptoms of hyperactivity-impulsivity have been present for at least 6 months to an extent that is disruptive and inappropriate for developmental level: – Often fidgets with hands or feet or squirms in seat. – Often gets up from seat when remaining in seat is expected. – Often runs about or climbs when and where it is not appropriate. – Often has trouble playing or enjoying leisure activities quietly. – Is often quot;on the goquot; or often acts as if quot;driven by a motorquot;. – Often talks excessively.
  • 14. Introduction: What is ADHD? • (B)Impulsivity (Continued) – Often blurts out answers before questions have been finished. – Often has trouble waiting one's turn. – Often interrupts or intrudes on others. – Some symptoms that cause impairment were present before age 7. – Some impairment from the symptoms is present in two or more settings (e.g. at school/work and at home). – Must be clear evidence of significant impairment in social, school, or work functioning. – The symptoms are not better accounted for by another mental disorder.
  • 15. What is ADHD? • ADHD, Combined Type: if both criteria 1A and 1B are met for the past 6 months • ADHD, Predominantly Inattentive Type: if criterion 1A is met but criterion 1B is not met for the past six months • ADHD, Predominantly Hyperactive-Impulsive Type: if Criterion 1B is met but Criterion 1A is not met for the past six months.
  • 16. Criticisms of the ADHD Diagnosis: Reliability of Diagnosis – Research shows low interater reliability of ADHD symptoms across countries, cultures, and even within cultures (Timimi et. al. , 2004) – Specifically, rates vary by a factor of 10 from county to county within individual states in the U.S. – A U.S. study showed that teachers rated 49% of boys as restless, 43% having short attention span and 43% as inattentive during conversations.
  • 17. Criticisms of the ADHD Diagnosis: Reliability of Diagnosis – An England Epidemiological study diagnosed only two children out of 2,199 with hyperactivity(.09%) (Armstrong, 1996). – In contrast, a study in Israel found that teachers rated 28% of students as hyperactive – 80% of patients diagnosed do not show symptoms in the physician’s office(Armstrong, 1996). – Prevalence Estimates range between 1 – 20%
  • 18. Criticisms of the ADHD Diagnosis: Subjective Ratings of Behavior – The most common assessment includes a checklist of behavior and scales for the frequency of the behavior exhibited. Ex: Scale rating of 1 – 5 (1 = almost never) and (5 = almost always) Items: “Restless(squirms in seat)”, “Fidgety(hands always busy)”, “Follow a sequence of instructions”
  • 19. Iowa Connor’s Teacher Rating Scale
  • 20. Criticisms of the ADHD Diagnosis: Subjective Ratings of Behavior • Children are rated by teachers and parents who have subjective biases, standards and expectations about their behavior. • These authority figures may have a proclivity towards the ADHD diagnoses in order to keep children compliant in either the home or school setting, as a result of medication or special education placement.
  • 21. Criticisms of the ADHD Diagnosis: Subjective Ratings of Behavior • These subjective measures of behavior are limited in scope considering they do not take into account the context or environment in which the child is currently in during time of assessment • A child may be a 5(almost always) on fidgetiness in one situation ( i.e. during school work) but a 1 at during more stimulating activities (i.e. recess, play time) • Therefore, assigning one number for all contexts and environments is not fully representative of a child’s true behavior.
  • 22. Criticisms of the ADHD Diagnosis: Subjective Ratings of Behavior • One study compared ratings of parents, teachers, and physicians for 5,000 elementary children. • 5% were considered hyperactive by one of the groups but only 1% were rated hyperactive by all 3 groups of raters. • Another study revealed that agreement between mothers and fathers on their child’s diagnosis of hyperactivity was only 32% • The study also showed that rating agreement between parents and teachers was even lower, at 13%.
  • 23. Criticisms of the ADHD Diagnosis: Subjective Ratings of Behavior • What is considered normal behavior in children? • Many normal children have problems with fidgetiness and attention. So where do we draw the line? • What about children at the other end of the spectrum, who are too compliant, and too focused? This issue is rarely addressed. • These evaluations are purely subjective, prone to error and bias, and not objective in their design.
  • 24. Criticisms: Objective Ratings of Behavior • (CPTs) – Continuous Performance Tasks – Measure patient’s selective attention to the presence or absence of stimuli during sets of distracters. • Ex: (GDS) – Gordon Diagnostic System – Patients press a button after specific sets of ordered digits have been flashed up on a computer screen. The number of correct responses and incorrect responses are recorded as “hits” and “ misses” respectively.
  • 25. Criticisms of the ADHD Diagnosis: Objective Ratings of Behavior • These tests of vigilance were developed to select promising candidates for radar operations during World War II. • Although CPTs intend to present an objective measure of children’s selective attention, they only tell how the child will perform on repetitive, mundane, and non-stimulating tasks irrelevant to what children encounter in their real lives. • Therefore, the validity of their current use with children today should be questioned.
  • 26. Criticisms of the ADHD Diagnosis: Temperament – Symptoms do not significantly differ from children who have normal variations in temperament (Carey, 1998). – This is especially true when children are given the chance to choose their own learning activities and perform at their own pace. (Armstrong, 1996). – Children with ADHD behave normally when exposed to interesting, novel, or stimulating tasks. – 70% of children diagnosed find ADHD symptoms disappear upon reaching adulthood. – Temperament research shows only about 50% of most populations sampled are attentive with the other 50% displaying below average attentiveness.
  • 27. Criticisms of the ADHD Diagnosis: Temperament • Currently, there is no supporting evidence for arbitrary cut off scores for abnormal levels of high activity and attentiveness (Levy, Hay, Mcstephen, et. Al., 1997). • Although children with difficult temperament (low adaptability , negative mood) and low task orientation (high energy, low persistence-attention span, high distractibility) experience more social problems and poor academic achievement respectively, these traits do not lead to dysfunction on their own, but only when other environmental problems occur as well.
  • 28. Criticisms: Co-morbidity • Co-existing conditions with ADHD include: – Problems with parent-child interaction – Family violence – Parental Psychopathology – Anxiety Disorder – (25-34%) – Bipolar disorder - (18-60%) – Depression – (18-60%) – Learning disabilities – (12-60%) – Conduct Disorder - (35-60%) – Oppositional Defiant Disorder – (35-60%)
  • 29. Co-morbidity • According to Pliszka (2000) most children who meet the criteria for conduct disorder or oppositional defiant disorder will also meet the criteria for ADHD. • Although medication is claimed to successfully treat all 3 conditions, Children with Conduct Disorder require additional intervention when there is also family psychopathology present. • This raises an obvious question if ADHD is an adequate diagnostic category to explain the child’s functioning in other domains in life.
  • 30. Co-morbidity • Learning disabilities can cause inattention and frustration and mask the presence of ADHD(Furman, 2006). • Although stimulants have been shown to improve reading scores, it is believed that these improvements are related to performances requiring repetition and concentration and not genuine learning.
  • 31. Co-morbidity • Although stimulants are used primarily to treat ADHD, they can be extremely harmful in treating co-morbid conditions such as mood disorders • Stimulants used to treat depression and bipolar disorder can cause dysphoria and harmful mood dysregulation. (Furman, 2006). • Clinicians who use stimulants to treat these co-morbid conditions must exercise extreme caution.
  • 32. Co-morbidity • According to evidence-based perspectives, Cognitive-Behavioral Therapy is the best known treatment modality for children with anxiety and ADHD. • In addition, children with ADHD and anxiety disorder do not respond as well to stimulant medication. • Unfortunately, symptoms of anxiety disorder are overlooked by providers and not considered during the assessment process as ADHD symptoms are probably more salient (Furman, 2006).
  • 33. Co-morbidity • The large amount of overlap between ADHD and other co-ocurring psychopathology provides additional support for the argument that ADHD is not a separate psychological or neurological condition.
  • 34. Criticisms: The Disease Model Of ADHD • ADHD is believed to be a neurodevelopmental brain disorder with biological predispositions and distinct etiology. • Potential causes include chemical abnormalities( serotonin, dopamine, norepinephrine), neurologica l damage, lead poisoning, thyroid dysfunction, prenatal exposure to harmful substances, and delayed transmission of nerve impulses. • Mechanistic view of human capacity, where the mind functions much like a machine.
  • 35. Criticisms: The Disease Model Of ADHD • Despite an emphasis on biological brain causes, no clear biological markers have ever been discovered in patients diagnosed with ADHD. • According to Carey(1998), children with brain damage show no clear pattern of hyperactivity or inattention and children diagnosed with ADHD show no consistent structural, functional or neurochemical abnormality. • Carey(1998) even points out that brain differences are present in healthy children who display variations in normal temperament.
  • 36. The Disease Model Of ADHD • Timimi(2002) also points out that there is no medical test to detect the presence of ADHD. • Neuroimaging studies have shown no clinical abnormalities between the brains of children diagnosed with ADHD and age matched-control groups (Hynd & Hooper, 1995) (Baumeister and Hawkins, 2001). • A Federal Government report on ADHD concluded that: “…there was no compelling evidence to support the claim that ADHD was a biochemical brain disorder” (National Institutes of Health, 1998).
  • 37. The Disease Model Of ADHD • However, many studies that claim to show biological evidence of ADHD have omitted important additional research that contradicts original findings. This notion is also reinforced by inaccurate media coverage. • For example, a study by Zametkin et. Al, 1990 at NIMH found a link between reduced metabolism of glucose and adult hyperactivity. • They concluded that deficits in the premotor and superior prefrontal cortex accounted for this inhibited metabolism of glucose.
  • 38. The Disease Model Of ADHD • Despite positive attention by departments of psychiatry and the media, an additional study by Zametkin et. Al, in 1993 found no significant differences between the brains of normal and hyperactive adolescents. • This contradictory finding to the study was not reported by the media or the ADHD community.
  • 39. Criticisms: Medication for ADHD • Methylphenidate, dextroamphetamine, and methamphetamine are the most popular psychostimulant treatments for ADHD. • An estimated “10-12 percent of all boys between the ages of 6 and 14 in the United States have been diagnosed as having ADHD and are being treated with methylphenidate.” • Breggin(1998) estimates that 4-5 million children receive psychostimulants in the U.S. each year.
  • 40. Criticisms: Medication for ADHD • However, these medications produce toxicity and general excitation of the Central Nervous System. • Have effects on neurotransmitters such as dopamine, norepinephrine, and serotonin. • Symptoms such as increased energy, hyperalertness, and hyperfocus are reported. • Other symptoms include insomnia, OCD, agitation, hypomania, mania, seiz ures, fatigue, lethargy, social withdrawal, and depression, irritability, anxiety, and emotional sensitivity.
  • 41. Medication for ADHD • Firestone et. al (1998), found preschool children ADHD who were treated with methylphenidate experienced greater social dampening effects when compared to a placebo group. • Such sideffects included: – “Talks less with others” - increased from 21% to 50% – “Uninterested in others” – increased from 31% to 75% – “Sad/Unhappy” – increased 47% to 84% – These findings are also consistent with those of Schleifer et. al. (1975) who also found “less social behavior and interaction, and increased solitary play” in ADHD children treated with methylphenidate.
  • 42. Medication for ADHD • A study by Mayes and colleagues (1994) found that children treated with methylphenidate were reported as “withdrawn, listless, depressed, dopey, dazed, subd ued, and inactive”. • This study also found that children suffered from somatic complaints including insomnia(13%), nausea or vomiting(11%), loss of appetite(20%), and headache(4%). • Schachar et. al. (1997) concluded that affective symptoms develop in later stages of drug treatment are often missed in most short term drug studies.
  • 43. Medication for ADHD • Firestone et al. (1998) also found increases in nervous movements (“tics”) in children treated with stimulant medication, with an increase from 3% (placebo) to 12% in children on methylphenidate. • Barkely et. al (1990) reported a 10% increase in abnormal movements in children treated with higher doses of methylphenidate. • Borcherding et. al. found 58% of their medicated children demonstrated abnormal nervous movements, with one permanent case of “tics”.
  • 44. Medication for ADHD • Breggin, 1998b; Kessler, 1993; Leber, 1992 highlight 2,821 reports of adverse reactions to methylphenidate in the Spontaneous Reporting System: – 1. More than 150 reports of liver abnormalities – 2. Sixty Nine reports of convulsions, 18 specifically grand mal. – 3. Eighty-seven reports of drug dependency, addiction – 4. Thirty reports of drug withdrawal – 5. Two hundred fifty reports of hair loss – 6.Fifty reports of leukopenia (low white blood cell count)
  • 45. Medication for ADHD • According to Karch (1996) several studies now show direct evidence that methylphenidate has cardiotoxic effects. • Specifically, Henderson & Fischer (1994) studied the effects on mice and discovered toxic effects within 3 weeks after using only minimum doses • Ishiguro & Morgan (1997) found that methylphenidate adminstered to ferrets at levels equal to clinical usage produced contraction problems in the heart muscles. • FDAs Spontaneous Reporting System found 121 reports of cardiovascular problems, with 9 cardiac arrests and 4 hearts failures (Elinwood & Tong, 1996).
  • 46. Medication for ADHD • According to the American Psychiatric Association (1994), methylphenidate: “In clinical studies…produces behavioral, psychological, subjective, and reinforcing effects similar to d-amphetamine and cocaine.” • “7% of Indiana high school students have used Ritalin non-medically at least once, and that about 2.5% of high school students use it on a monthly or more frequent basis” (Indiana Prevention Resource Center, 1998). • Breggin (1998a) believes that over medicating children teaches them to exert less control over their actions and behavior.
  • 47. Medication Research • Much medication research has been questionable in it’s design. • For example, the (MTA) NIMH Multimodal Treatment Study for ADHD had an abundance of errors in methodology yet claimed that stimulant treatment was superior to behavioral and community treatment. • Peter Breggin offers a critical analysis of this study and points out many of it’s limitations
  • 48. Medication Research • 1. The MTA was not a placebo controlled, double blind clinical trial. – Investigators relied on ratings made by teachers and parents who were not blind to the treatment - “Open label studies” which are often discredited. • 2. The study used no control group of untreated children. – The study only compared 3 drug conditions to behavioral treatments • 3. Thirty-two percent of the Medication Management group was already taking medication before hand. – Created unequal participants for the study due to history
  • 49. Medication Research • 4. Blind classroom raters observed no difference between treatment groups – Although medication did not demonstrate any superior benefits behavioral treatments, this finding was withheld from the studies’ conclusions • 5. Drug treatments exceeded behavioral treatments in length of duration. – This bias could appear to make medication a more effective treatment then behavioral treatments
  • 50. Medication Research • 6. Children in the drug treatment group did not rate themselves as feeling improved. – This important finding was also omitted from the study’s conclusions as well • 7. All of the principal investigators were well known drug advocates – Received funding from Richwood, Bristol- Myers, Solvay, Wyeth-Ayerst, Glaxo, and Eli Lilly • 8. Parents and teachers were exposed to drug propaganda. – Parents were told their children would be treated with “safe effective doses of medication”
  • 51. Overlooked Factors: Nutrition • A nutrition approach takes longer to show results. “With dietary supplements you can see improvement in behavior in a week or two,” says Zimmerman. “A food approach is more of a long-term thing—a 30-day plan, for example.”
  • 52. George Washington University • A study by George Washington University found that hyperactive children who ate a meal high in protein did equally well or sometimes even better in school then non hyperactive kids
  • 53. Fatty acids • What are they? What are some examples? Where do you get them from?
  • 54. Oxford University • Oxford University found that the ADHD symptoms in children receiving essential fatty acids improved over children in a control group receiving a placebo
  • 55. Overlooked Factors: Nutrition • Researchers further documented the essential fatty acid deficiency tie to Attention Deficit Disorder in a 1987 study. Then, a 1995 study comparing essential fatty acid levels in ADHD boys against a control group of boys without ADHD found significantly lower levels of Omega-3 fatty acids.
  • 56. Overlooked Factors: Nutrition • In 1996 Purdue University researchers have found that boys with low blood levels of Omega-3 fatty acids have a greater frequency of Attention Deficit Disorder ADHD.
  • 57. Food Coloring • Study done by South Hampton University in UK • EFSA’s advice given to ADHD parents • Types of food coloring used
  • 58. Overlooked Factors: American Culture • Change in the cultural expectations of children – Children now are expected to behave in ways that are not always developmentally appropriate – Many view these high expectations as an end to childhood innocence, coupled with the fact that children are constantly exposed to adult information via media and television (Postman 1983). – Children are now seen as a danger to society and need to be controlled, reshaped and changed.
  • 59. Overlooked Factors: American Culture • With more anxiety in place regarding childrearing, but also fear of state intervention in domestic affairs, ADHD offers a shift away from social dilemmas and onto the child. (Timimi, 2002). • Parents feel economic pressures to work long hours leaving medication the most convenient “quick fix” treatment for ADHD and less time for family therapy approaches involving parent-child interaction (Furman, 2006).
  • 60. Overlooked Factors: American Schools • Public school system curriculums are tailored mainly towards academics such as reading, writing, arithmetic, and standardized testing, and leave less emphasis on creative and engaging activities. • Thus, students who do no excel in these areas but in others such as the arts, physical activities, or hands-on kinesthetic learning are not in an environment that is conducive to their style of learning
  • 61. Overlooked Factors: American Schools • Therefore these students fall through the cracks and receive less assistance for their special needs of learning and are viewed as having a biological brain disorder.
  • 62. Overlooked Factors: Alternative Treatment • According to Breggin (2000), ADHD can be treated through means other than medication such as individualized family counseling and educational approaches to empower children, parents teachers and others.
  • 63. Overlooked Factors: Alternative Treatment • Applied behavior analysis is an overlooked yet effective method for improving behavior in school. • According to Packard (1970), classroom attention can be achieved and maintained in students when teacher instruction is coupled with group contingencies. • For example, in Packard’s (1970) study, the instructor turned on a red light-timer device whenever a student was not paying attention.
  • 64. Overlooked Factors: Alternative Treatment • When all students showed proper attention, the teacher turned off the device. • Classrooms were rewarded with play activities upon maintenance of attention and teachers gave verbal feedback as to what percentage of the class paid attention. All students achieved 90- 100% levels of classroom attention. • Therefore, Packard (1970) concluded that it is possible to motivate students to pay attention when an appropriate and appealing reward system is implemented.
  • 65. Improving the ADHD Epidemic (Carey) 2005 • 1. Improved diagnostic system - Distinctions must be made between hyperkinetic children, who are truly pervasively overactive or inattentive, and those primarily having other problems • 2. Better research - Much is still unknown about the origin of ADHD and additional research is needed to adequately conceptualize and treat what appears not to be a biologically based psychological disorder.
  • 66. Improving the ADHD Epidemic (Carey) 2005 • 3. More education of professionals and public – People need more information about important matters such as normal variations in temperament and the non-specificity and harmful side effects of stimulant medications. • 4. Better evaluations – Children should undergo educational testing to rule out learning disabilities as the main cause of their behavior and also examine the child’s temperament and adjustment.
  • 67. Improving the ADHD Epidemic (Carey) 2005 • 5. Improved treatment – Greater reliance on psychosocial and educational interventions. Treatments should also be geared to build on the child’s strengths and remediate their weaknesses. • 6. Close monitoring of drug company advertising and promotion • 7. Regulation of both medical diagnosis and teacher insistence on medication.
  • 68. Conclusion • ADHD should be questioned until more sound scientific evidence becomes available to consider it a distinct neurological condition. • Parents and practitioners should remain skeptical of the disorder and be cautioned against a quick assignment to the ADHD diagnosis. • The risks of medication and stigmatization are too harmful to unique children who hold so much potential.
  • 69. The End Thank you for watching.

Notas do Editor

  1. Therefore the expectation that ALL young children must maintain attention in structured environments is unreasonable.
  2. Thus, the fact that humans are complex beings with varying demands is largely overlooked.
  3. 1. They are used to make brain and nervous tissue, there are two types omega 3 and omega 6. Omega 6 is the type of fatty acids that most americans have because they are found in oil, and shortening. Omega 3 is what most americans lack in because they are found in foods such as salmon and sardines.
  4. Study showed that aritfical food colors could be linked to negative effects on childrens behaviorsRecoomendation to parents that if there children have ADHD then they should try taking out food coloring from there diet3. Sunset yellow (E110)Quinoline yellow (E104)Carmoisine (E122)Allura red (E129)Sodium benzoate (E211)Tartrazine (E102)Carmoisine (E122)Ponceau 4R (E124)Sodium benzoate (E211)