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Cell-Structure &
    functions
What is cell ?
• The cell is the functional basic unit
  of life. It was discovered by
  Robert Hooke and is the functional
  unit of all known living organisms. It
  is the smallest unit of life that is
  classified as a living thing, and is
  often called the building block of life.
  Some organisms, such as most
  bacteria, are unicellular (consist of a
  single cell). Other organisms, such as
  humans, are multicellular. Humans
  have about 100 trillion cells;
• The descriptive term for the
  smallest living biological structure
  was coined by Robert Hooke in a
  book he published in 1665 when
  he compared the cork cells he saw
  through his microscope to the
  small rooms monks lived in.


Cork cell as observed
 by Robert Hooke
• Both, bricks in a building and cells in
  the living organisms, are base
  structural units. The buildings,
  though built of similar bricks have
  different designs, shapes and sizes.
  Similarly, in the living world,
  organisms differ from one another but
  all are made up of cells. Cells in the
  living organisms are complex living
  structures unlike non-living bricks.
  The egg of a hen represents a single
  cell and is big enough to be seen by
  unaided eye.
Brick wall   Onion peel
Anatomy

• There are two types of cells: eukaryotic
  and prokaryotic. Prokaryotic cells are
  those cells which have nuclear material
  without nuclear membrane. For ex-
  bacteria and blue green algae. The cell
  having well- organised nucleus with a
  nuclear membrane are called eukaryotic
  cells. For ex- onion cells and cheek cells.
• Generally, cells are round, spherical or
  elongated some cells are long and
  pointed at both ends. They exhibit a
  spindle shape. Cells sometimes are
  quite long. Some are branched like
  nerve cells or a neuron. Some are
  sphere like RBC.
Spherical red blood
                                              cells


                       Long
                         branched
                         nerve cells



Spindle shaped muscle cells
Animal cell
• An animal cell is a form of
  eukaryotic cell that makes up many
  tissues in animals. The animal cell is
  distinct from other eukaryotes, most
  notably plant cells, as they lack
  cell walls and chloroplasts, and they
  have smaller vacuoles. Due to the lack
  of a rigid cell wall, animal cells can
  adopt a variety of shapes, and a
  phagocytic cell can even engulf other
  structures.
Animal cell
•There are many different
 cell types. For instance,
 there are approximately
 210 distinct cell types in
 the adult human body.
Plant cell
• Plant cells are quite different
  from the cells of the other
  eukaryotic organisms. Their
  distinctive features are:
• A large central vacuole
  (enclosed by a membrane, the
  tonoplast), which maintains
  the cell's turgor and controls
  movement of molecules
  between the cytosol and sap
• A primary cell wall containing cellulose
  , hemicellulose and pectin, deposited by
  the protoplast on the outside of the cell
  membrane
• Chloroplasts that contain chlorophyll,
  the pigment that gives plants their
  green color and allows them to perform
  photosynthesis
• Higher plants, including conifers and
  flowering plants lack the flagella and
  centrioles that are present in
  animal cells.
Plant cell
Comparison of structures between
    animal and plant cells
Typical animal cell          Typical plant
                             cell
Nucleus                      Nucleus
Nucleolus (within nucleus)   Nucleolus (within
                             nucleus)
Rough ER                     Rough ER

Smooth ER                    Smooth ER

Ribosomes                    Ribosomes
Organelles Cytoskeleton Cytoskeleton
            Golgi        Golgi
            apparatus    apparatus
            Cytoplasm    Cytoplasm

            Mitochondria Mitochondria

            Vesicles     Plastids

            Lysosomes    Vacuole(s)

            Centrioles   Cell wall
Prokaryotic cells

• The prokaryote cell is simpler, and
  therefore smaller, than a eukaryote
  cell, lacking a nucleus and most of the
  other organelles of eukaryotes. There
  are two kinds of prokaryotes: bacteria
  and archaea (extremophiles) ; these
  share a similar structure.
Prokaryotic cell
• Nuclear material of prokaryotic cell
  consists of a single chromosome that is
  in direct contact with cytoplasm.
  Here, the undefined nuclear region in
  the cytoplasm is called nucleoid.
• A prokaryotic cell has three
  architectural regions:
• On the outside, flagella and pili
  project from the cell's surface. These
  are structures (not present in all
  prokaryotes) made of proteins that
  facilitate movement and
  communication between cells.
• Enclosing the cell is the cell envelope –
  generally consisting of a cell wall
  covering a plasma membrane though
  some bacteria also have a further
  covering layer called a capsule. The
  envelope gives rigidity to the cell and
  separates the interior of the cell from its
  environment, serving as a protective
  filter. Though most prokaryotes have a
  cell wall, there are exceptions such as
  Mycoplasma (bacteria) and
  Thermoplasma (archaea).
• The cell wall consists of peptidoglycan
     in bacteria, and acts as an additional
     barrier against exterior forces. It also
     prevents the cell from expanding and
     finally bursting (cytolysis) from
     osmotic pressure against a hypotonic
     environment. Some eukaryote cells
     (plant cells and fungi cells) also have a
     cell wall.

    Peptidoglycan is a polymer consisting of sugars and
    amino acids that forms a mesh-like layer outside the
plasma membrane of bacteria (but not Archaea), forming the

                        cell wall.
• Inside the cell is the
  cytoplasmic region that contains the
  DNA and ribosomes and various sorts
  of inclusions. A
  prokaryotic chromosome is usually a
  circular molecule (an exception is that
  of the bacterium Borrelia, which
  causes Lyme disease). Though not
  forming a nucleus, the DNA is
  condensed in a nucleoid.
• Prokaryotes can carry
  extrachromosomal DNA elements
  called plasmids, which are usually
  circular. Plasmids enable
  additional functions, such as
  antibiotic resistance.
Eukaryotic cells
• Plants, animals, fungi, slime moulds,
  protozoa, & algae are all Eukaryotic.
  These cells are about 15 times wider
  than a typical prokaryote and can be
  as much as 1000 times greater in
  volume. The major difference between
  prokaryotes and eukaryotes is that
  eukaryotic cells contain membrane-
  bound compartments in which specific
  metabolic activities take place.
• Most important among these
  is a cell nucleus, a membrane-
  delineated compartment that
  houses the eukaryotic cell's
  DNA.
Eukaryotic cell
                                    Endoplasmi
                                    c reticulum
       Free
       ribosome
   Mitochond                             Ribosome
   ria
Cell                                     Nucleus
membran
e




                                     Cell wall
• Other differences include: The plasma
  membrane resembles that of prokaryotes in
  function, with minor differences in the
  setup. Cell walls may or may not be present.
• The eukaryotic DNA is organized in one or
  more linear molecules, called chromosomes,
  which are associated with histone proteins.
  All chromosomal DNA is stored in the
  cell nucleus, separated from the cytoplasm by
  a membrane. Some eukaryotic organelles
  such as mitochondria also contain some
  DNA.
• Eukaryotes can move using
  motile cilia or flagella. The
  flagella are more complex than
  those of prokaryotes.


                         Flagella or cilia
Comparison of features of prokaryotic
       and eukaryotic cells
             Prokaryotes      Eukaryotes

Typical      bacteria, blue   fungi, plants,
organisms    green algae      animals

Type of      nucleoid region; real nucleus
nucleus      no real nucleus with double
                              membrane

DNA          circular         linear molecules
             (usually)        (chromosomes)
                              with histone
                              proteins
Cytoplasmati very few highly structured by
c structure  structures endomembranes and a
                        cytoskeleton

Mitochondri none        one to several
a                       thousand (though
                        some lack
                        mitochondria)

Chloroplasts none       in algae and plants

Organization usually    single cells, colonies,
             single     higher multicellular
             cells      organisms with
                        specialized cells
Cell structure
• Cell nucleus- The cell nucleus is the
  most conspicuous organelle found in a
  eukaryotic cell. It houses the cell's
  chromosomes, and is the place where
  almost all DNA replication and RNA
  synthesis (transcription) occur. The
  nucleus is spherical and separated
  from the cytoplasm by a double
  membrane called the nuclear envelope.
• The nuclear envelope isolates and
  protects a cell's DNA from various
  molecules that could accidentally
  damage its structure or interfere with
  its processing. During processing,
  DNA (deoxyribonucliec acid) is copied
  into a special RNA (ribonucliec acid),
  called messenger RNA (mRNA). This
  mRNA is then transported out of the
  nucleus, where it is translated into a
  specific protein molecule. The
  nucleolus is a specialized region
  within the nucleus where ribosome
  subunits are assembled. In
  prokaryotes, DNA processing takes
  place in the cytoplasm.
Cell nucleus




               Nucleolus
Mitochondria and
      Chloroplasts
• Mitochondria and Chloroplasts are
  present in eukaryotes only.
  Mitochondria are self-replicating
  organelles that occur in various
  numbers, shapes, and sizes in the
  cytoplasm of all eukaryotic cells.
  Mitochondria play a critical role in
  generating energy in the eukaryotic
  cell.
Chloroplasts
• Mitochondria multiply by splitting in
  two. Respiration occurs in the cell
  mitochondria.
• Organelles that are modified
  chloroplasts are broadly called plastids
  , and are involved in energy storage
  through photosynthesis, which uses
  solar energy to generate carbohydrates
  and oxygen from carbon dioxide and
  water.
• Mitochondria and chloroplasts each
  contain their own genome, which is
  separate and distinct from the nuclear
  genome of a cell. Both organelles
  contain this DNA in circular
  plasmids. Since these organelles
  contain their own genomes and have
  other similarities to prokaryotes, they
  are thought to have developed through
  a symbiotic relationship after being
  engulfed by a primitive cell.
Endoplasmic reticulum
          (ER)
• Endoplasmic reticulum is present
  in eukaryotes only.  The
  endoplasmic reticulum (ER) is the
  transport network for molecules
  targeted for certain modifications
  and specific destinations, as
  compared to molecules that float
  freely in the cytoplasm.
• The ER has two forms: the
  rough ER, which has
  ribosomes on its surface and
  secretes proteins into the
  cytoplasm, and the smooth
  ER, which lacks them. Smooth
  ER plays a role in calcium
  sequestration and release.
Ribosomes
• The ribosome is a large complex of
  RNA and protein molecules. They
  each consist of two subunits, and act
  as an assembly line where RNA from
  the nucleus is used to synthesize
  proteins from amino acids. Ribosomes
  can be found
• either floating freely or bound to a
  membrane (the rough endoplasmatic
  reticulum in eukaryotes, or the cell
  membrane in prokaryotes).
Lysosomes and
        Peroxisomes
• Lysosomes and Peroxisomes are
  present in eukaryotes only.
  Lysosomes contain
  digestive enzymes (acid hydrolases
  ). They digest excess or worn-out
  organelles, food particles, and
  engulfed viruses or bacteria.
  Peroxisomes have enzymes that
  rid the cell of toxic peroxides.
• The cell could not house these
  destructive enzymes if they were
  not contained in a membrane-
  bound system. These organelles
  are often called a "suicide bag"
  because of their ability to
  detonate and destroy the cell.
Vacuoles 
• Vacuoles store food and waste. Some
  vacuoles store extra water. They are
  often described as liquid filled space
  and are surrounded by a membrane.
  Some cells, most notably Amoeba,
  have contractile vacuoles, which can
  pump water out of the cell if there is
  too much water. The vacuoles of
  eukaryotic cells are usually larger in
  those of plants than animals.
Flagella

• Flagella are the organelles of cellular
  mobility. They arise from cytoplasm
  and extrude through the cell wall.
  They are long and thick thread-like
  appendages, protein in nature. Are
  most commonly found in bacteria cells
  but are found in animal cells as well.
Fimbriae (pili)
• They are short and thin hair like
  filaments, formed of protein called
  pilin. Fimbriae are responsible for
  attachment of bacteria to specific
  receptors of human cell. There are
  special types of pili involved in
  conjunction.
Fimbriae (pili)
Golgi apparatus
• The golgi apparatus is an organelle
  found in most eukaryotic cells. It was
  identified in 1897 by the italian
  physician Camillo Golgi, after whom
  golgi apparatus is named. process and
  package the macromolecules such as
  proteins and lipids (fats) that are
  synthesized by the cell.
• It is particularly important in the
  processing of proteins for
  secretion. The Golgi apparatus
  forms a part of the endomembrane
  system of eukaryotic cells.
Cytoskeleton

• The cytoskeleton acts to organize and
  maintain the cell's shape; anchors
  organelles in place; helps during
  endocytosis, the uptake of external
  materials by a cell, and cytokinesis,
  the separation of daughter cells after
  cell division; and moves parts of the
  cell in processes of growth and
  mobility.
• There is a great number of proteins
  associated with them, each controlling
  a cell's structure by directing,
  bundling, and aligning filaments. The
  prokaryotic cytoskeleton is less well-
  studied but is involved in the
  maintenance of cell shape and
  cytokinesis.
Functions

1.   Growth and metabolism
2.   Creation
3.   Protein synthesis
4.   Movement or motility
Growth and metabolism

• Between successive cell divisions,
  cells grow through the
  functioning of cellular
  metabolism. Cell metabolism is the
  process by which individual cells
  process nutrient molecules.
• Metabolism has two distinct
  divisions: catabolism, in which the
  cell breaks down complex molecules to
  produce energy and reducing power,
  and anabolism, in which the cell uses
  energy and reducing power to
  construct complex molecules and
  perform other biological functions.
  Complex sugars consumed by the
  organism can be broken down into a
  less chemically complex sugar molecule
  called glucose. Once inside the cell,
  glucose is broken down to make
  adenosine triphosphate (ATP), a form
  of energy, through two different
  pathways.
• The first pathway, glycolysis, requires
  no oxygen and is referred to as
  anaerobic metabolism. Each reaction
  is designed to produce some hydrogen
  ions that can then be used to make
  energy packets (ATP). In prokaryotes,
  glycolysis is the only method used for
  converting energy.
• The second pathway, called the Krebs
  cycle, or citric acid cycle, occurs inside
  the mitochondria and can generate
  enough ATP to run all the cell
  functions.
Creation
• Cell division involves a single cell
  (called a mother cell) dividing into
  two daughter cells. This leads to
  growth in multicellular organisms (the
  growth of tissue) and to procreation (
  vegetative reproduction) in
  unicellular organisms.
• Prokaryotic cells divide by
  binary fission. Eukaryotic cells
  usually undergo a process of nuclear
  division, called mitosis, followed by
  division of the cell, called cytokinesis.
  A diploid cell may also undergo
  meiosis to produce haploid cells,
  usually four. Haploid cells serve as
  gametes in multicellular organisms,
  fusing to form new diploid cells.
• DNA replication, or the process
  of duplicating a cell's genome, is
  required every time a cell divides.
  Replication, like all cellular
  activities, requires specialized
  proteins for carrying out the job.
Protein synthesis
• Cells are capable of synthesizing new
  proteins, which are essential for the
  modulation and maintenance of
  cellular activities. This process
  involves the formation of new protein
  molecules from amino acid building
  blocks based on information encoded
  in DNA/RNA. Protein synthesis
  generally consists of two major steps:
  transcription and translation.
• Transcription is the process where
  genetic information in DNA is
  used to produce a complementary
  RNA strand. This RNA strand is
  then processed to give messenger
  RNA (mRNA), which is free to
  migrate through the cell. mRNA
  molecules bind to protein-RNA
  complexes called ribosomes located
  in the cytosol.
Movement or motility

• Cells can move during many processes:
  such as wound healing, the immune
  response and cancer metastasis. For
  wound healing to occur, white blood
  cells and cells that ingest bacteria
  move to the wound site to kill the
  microorganisms that cause infection.
  At the same time fibroblasts
  (connective tissue cells) move there to
  remodel damaged structures.
•In the case of tumor
 development, cells from a
 primary tumor move
 away and spread to other
 parts of the body. Cell
 motility involves many
 receptors, cross linking,
 bundling, binding,
 adhesion, motor and
 other proteins.
• The process is divided into three
  steps – protrusion of the leading
  edge of the cell, adhesion of the
  leading edge and de-adhesion at the
  cell body and rear, and cytoskeletal
  contraction to pull the cell forward.
  Each step is driven by physical
  forces generated by unique segments
  of the cytoskeleton.
Presented by -
Anushka Ninama
 Class- VIII th
Cell structure and functions

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Cell structure and functions

  • 1. Cell-Structure & functions
  • 2. What is cell ? • The cell is the functional basic unit of life. It was discovered by Robert Hooke and is the functional unit of all known living organisms. It is the smallest unit of life that is classified as a living thing, and is often called the building block of life. Some organisms, such as most bacteria, are unicellular (consist of a single cell). Other organisms, such as humans, are multicellular. Humans have about 100 trillion cells;
  • 3. • The descriptive term for the smallest living biological structure was coined by Robert Hooke in a book he published in 1665 when he compared the cork cells he saw through his microscope to the small rooms monks lived in. Cork cell as observed by Robert Hooke
  • 4. • Both, bricks in a building and cells in the living organisms, are base structural units. The buildings, though built of similar bricks have different designs, shapes and sizes. Similarly, in the living world, organisms differ from one another but all are made up of cells. Cells in the living organisms are complex living structures unlike non-living bricks. The egg of a hen represents a single cell and is big enough to be seen by unaided eye.
  • 5. Brick wall Onion peel
  • 6. Anatomy • There are two types of cells: eukaryotic and prokaryotic. Prokaryotic cells are those cells which have nuclear material without nuclear membrane. For ex- bacteria and blue green algae. The cell having well- organised nucleus with a nuclear membrane are called eukaryotic cells. For ex- onion cells and cheek cells.
  • 7. • Generally, cells are round, spherical or elongated some cells are long and pointed at both ends. They exhibit a spindle shape. Cells sometimes are quite long. Some are branched like nerve cells or a neuron. Some are sphere like RBC.
  • 8. Spherical red blood cells Long branched nerve cells Spindle shaped muscle cells
  • 9. Animal cell • An animal cell is a form of eukaryotic cell that makes up many tissues in animals. The animal cell is distinct from other eukaryotes, most notably plant cells, as they lack cell walls and chloroplasts, and they have smaller vacuoles. Due to the lack of a rigid cell wall, animal cells can adopt a variety of shapes, and a phagocytic cell can even engulf other structures.
  • 11. •There are many different cell types. For instance, there are approximately 210 distinct cell types in the adult human body.
  • 12. Plant cell • Plant cells are quite different from the cells of the other eukaryotic organisms. Their distinctive features are: • A large central vacuole (enclosed by a membrane, the tonoplast), which maintains the cell's turgor and controls movement of molecules between the cytosol and sap
  • 13. • A primary cell wall containing cellulose , hemicellulose and pectin, deposited by the protoplast on the outside of the cell membrane • Chloroplasts that contain chlorophyll, the pigment that gives plants their green color and allows them to perform photosynthesis • Higher plants, including conifers and flowering plants lack the flagella and centrioles that are present in animal cells.
  • 15. Comparison of structures between animal and plant cells Typical animal cell Typical plant cell Nucleus Nucleus Nucleolus (within nucleus) Nucleolus (within nucleus) Rough ER Rough ER Smooth ER Smooth ER Ribosomes Ribosomes
  • 16. Organelles Cytoskeleton Cytoskeleton Golgi Golgi apparatus apparatus Cytoplasm Cytoplasm Mitochondria Mitochondria Vesicles Plastids Lysosomes Vacuole(s) Centrioles Cell wall
  • 17. Prokaryotic cells • The prokaryote cell is simpler, and therefore smaller, than a eukaryote cell, lacking a nucleus and most of the other organelles of eukaryotes. There are two kinds of prokaryotes: bacteria and archaea (extremophiles) ; these share a similar structure.
  • 19. • Nuclear material of prokaryotic cell consists of a single chromosome that is in direct contact with cytoplasm. Here, the undefined nuclear region in the cytoplasm is called nucleoid. • A prokaryotic cell has three architectural regions: • On the outside, flagella and pili project from the cell's surface. These are structures (not present in all prokaryotes) made of proteins that facilitate movement and communication between cells.
  • 20. • Enclosing the cell is the cell envelope – generally consisting of a cell wall covering a plasma membrane though some bacteria also have a further covering layer called a capsule. The envelope gives rigidity to the cell and separates the interior of the cell from its environment, serving as a protective filter. Though most prokaryotes have a cell wall, there are exceptions such as Mycoplasma (bacteria) and Thermoplasma (archaea).
  • 21. • The cell wall consists of peptidoglycan in bacteria, and acts as an additional barrier against exterior forces. It also prevents the cell from expanding and finally bursting (cytolysis) from osmotic pressure against a hypotonic environment. Some eukaryote cells (plant cells and fungi cells) also have a cell wall. Peptidoglycan is a polymer consisting of sugars and amino acids that forms a mesh-like layer outside the plasma membrane of bacteria (but not Archaea), forming the cell wall.
  • 22. • Inside the cell is the cytoplasmic region that contains the DNA and ribosomes and various sorts of inclusions. A prokaryotic chromosome is usually a circular molecule (an exception is that of the bacterium Borrelia, which causes Lyme disease). Though not forming a nucleus, the DNA is condensed in a nucleoid.
  • 23. • Prokaryotes can carry extrachromosomal DNA elements called plasmids, which are usually circular. Plasmids enable additional functions, such as antibiotic resistance.
  • 24. Eukaryotic cells • Plants, animals, fungi, slime moulds, protozoa, & algae are all Eukaryotic. These cells are about 15 times wider than a typical prokaryote and can be as much as 1000 times greater in volume. The major difference between prokaryotes and eukaryotes is that eukaryotic cells contain membrane- bound compartments in which specific metabolic activities take place.
  • 25. • Most important among these is a cell nucleus, a membrane- delineated compartment that houses the eukaryotic cell's DNA.
  • 26. Eukaryotic cell Endoplasmi c reticulum Free ribosome Mitochond Ribosome ria Cell Nucleus membran e Cell wall
  • 27. • Other differences include: The plasma membrane resembles that of prokaryotes in function, with minor differences in the setup. Cell walls may or may not be present. • The eukaryotic DNA is organized in one or more linear molecules, called chromosomes, which are associated with histone proteins. All chromosomal DNA is stored in the cell nucleus, separated from the cytoplasm by a membrane. Some eukaryotic organelles such as mitochondria also contain some DNA.
  • 28. • Eukaryotes can move using motile cilia or flagella. The flagella are more complex than those of prokaryotes. Flagella or cilia
  • 29. Comparison of features of prokaryotic and eukaryotic cells Prokaryotes Eukaryotes Typical bacteria, blue fungi, plants, organisms green algae animals Type of nucleoid region; real nucleus nucleus no real nucleus with double membrane DNA circular linear molecules (usually) (chromosomes) with histone proteins
  • 30. Cytoplasmati very few highly structured by c structure structures endomembranes and a cytoskeleton Mitochondri none one to several a thousand (though some lack mitochondria) Chloroplasts none in algae and plants Organization usually single cells, colonies, single higher multicellular cells organisms with specialized cells
  • 31. Cell structure • Cell nucleus- The cell nucleus is the most conspicuous organelle found in a eukaryotic cell. It houses the cell's chromosomes, and is the place where almost all DNA replication and RNA synthesis (transcription) occur. The nucleus is spherical and separated from the cytoplasm by a double membrane called the nuclear envelope.
  • 32. • The nuclear envelope isolates and protects a cell's DNA from various molecules that could accidentally damage its structure or interfere with its processing. During processing, DNA (deoxyribonucliec acid) is copied into a special RNA (ribonucliec acid), called messenger RNA (mRNA). This mRNA is then transported out of the nucleus, where it is translated into a specific protein molecule. The nucleolus is a specialized region within the nucleus where ribosome subunits are assembled. In prokaryotes, DNA processing takes place in the cytoplasm.
  • 33. Cell nucleus Nucleolus
  • 34. Mitochondria and Chloroplasts • Mitochondria and Chloroplasts are present in eukaryotes only. Mitochondria are self-replicating organelles that occur in various numbers, shapes, and sizes in the cytoplasm of all eukaryotic cells. Mitochondria play a critical role in generating energy in the eukaryotic cell.
  • 36. • Mitochondria multiply by splitting in two. Respiration occurs in the cell mitochondria. • Organelles that are modified chloroplasts are broadly called plastids , and are involved in energy storage through photosynthesis, which uses solar energy to generate carbohydrates and oxygen from carbon dioxide and water.
  • 37.
  • 38. • Mitochondria and chloroplasts each contain their own genome, which is separate and distinct from the nuclear genome of a cell. Both organelles contain this DNA in circular plasmids. Since these organelles contain their own genomes and have other similarities to prokaryotes, they are thought to have developed through a symbiotic relationship after being engulfed by a primitive cell.
  • 39. Endoplasmic reticulum (ER) • Endoplasmic reticulum is present in eukaryotes only.  The endoplasmic reticulum (ER) is the transport network for molecules targeted for certain modifications and specific destinations, as compared to molecules that float freely in the cytoplasm.
  • 40.
  • 41. • The ER has two forms: the rough ER, which has ribosomes on its surface and secretes proteins into the cytoplasm, and the smooth ER, which lacks them. Smooth ER plays a role in calcium sequestration and release.
  • 42. Ribosomes • The ribosome is a large complex of RNA and protein molecules. They each consist of two subunits, and act as an assembly line where RNA from the nucleus is used to synthesize proteins from amino acids. Ribosomes can be found
  • 43.
  • 44. • either floating freely or bound to a membrane (the rough endoplasmatic reticulum in eukaryotes, or the cell membrane in prokaryotes).
  • 45. Lysosomes and Peroxisomes • Lysosomes and Peroxisomes are present in eukaryotes only. Lysosomes contain digestive enzymes (acid hydrolases ). They digest excess or worn-out organelles, food particles, and engulfed viruses or bacteria. Peroxisomes have enzymes that rid the cell of toxic peroxides.
  • 46.
  • 47. • The cell could not house these destructive enzymes if they were not contained in a membrane- bound system. These organelles are often called a "suicide bag" because of their ability to detonate and destroy the cell.
  • 48. Vacuoles  • Vacuoles store food and waste. Some vacuoles store extra water. They are often described as liquid filled space and are surrounded by a membrane. Some cells, most notably Amoeba, have contractile vacuoles, which can pump water out of the cell if there is too much water. The vacuoles of eukaryotic cells are usually larger in those of plants than animals.
  • 49.
  • 50. Flagella • Flagella are the organelles of cellular mobility. They arise from cytoplasm and extrude through the cell wall. They are long and thick thread-like appendages, protein in nature. Are most commonly found in bacteria cells but are found in animal cells as well.
  • 51. Fimbriae (pili) • They are short and thin hair like filaments, formed of protein called pilin. Fimbriae are responsible for attachment of bacteria to specific receptors of human cell. There are special types of pili involved in conjunction.
  • 53. Golgi apparatus • The golgi apparatus is an organelle found in most eukaryotic cells. It was identified in 1897 by the italian physician Camillo Golgi, after whom golgi apparatus is named. process and package the macromolecules such as proteins and lipids (fats) that are synthesized by the cell.
  • 54. • It is particularly important in the processing of proteins for secretion. The Golgi apparatus forms a part of the endomembrane system of eukaryotic cells.
  • 55. Cytoskeleton • The cytoskeleton acts to organize and maintain the cell's shape; anchors organelles in place; helps during endocytosis, the uptake of external materials by a cell, and cytokinesis, the separation of daughter cells after cell division; and moves parts of the cell in processes of growth and mobility.
  • 56. • There is a great number of proteins associated with them, each controlling a cell's structure by directing, bundling, and aligning filaments. The prokaryotic cytoskeleton is less well- studied but is involved in the maintenance of cell shape and cytokinesis.
  • 57. Functions 1. Growth and metabolism 2. Creation 3. Protein synthesis 4. Movement or motility
  • 58. Growth and metabolism • Between successive cell divisions, cells grow through the functioning of cellular metabolism. Cell metabolism is the process by which individual cells process nutrient molecules.
  • 59. • Metabolism has two distinct divisions: catabolism, in which the cell breaks down complex molecules to produce energy and reducing power, and anabolism, in which the cell uses energy and reducing power to construct complex molecules and perform other biological functions. Complex sugars consumed by the organism can be broken down into a less chemically complex sugar molecule called glucose. Once inside the cell, glucose is broken down to make adenosine triphosphate (ATP), a form of energy, through two different pathways.
  • 60. • The first pathway, glycolysis, requires no oxygen and is referred to as anaerobic metabolism. Each reaction is designed to produce some hydrogen ions that can then be used to make energy packets (ATP). In prokaryotes, glycolysis is the only method used for converting energy. • The second pathway, called the Krebs cycle, or citric acid cycle, occurs inside the mitochondria and can generate enough ATP to run all the cell functions.
  • 61. Creation • Cell division involves a single cell (called a mother cell) dividing into two daughter cells. This leads to growth in multicellular organisms (the growth of tissue) and to procreation ( vegetative reproduction) in unicellular organisms.
  • 62. • Prokaryotic cells divide by binary fission. Eukaryotic cells usually undergo a process of nuclear division, called mitosis, followed by division of the cell, called cytokinesis. A diploid cell may also undergo meiosis to produce haploid cells, usually four. Haploid cells serve as gametes in multicellular organisms, fusing to form new diploid cells.
  • 63. • DNA replication, or the process of duplicating a cell's genome, is required every time a cell divides. Replication, like all cellular activities, requires specialized proteins for carrying out the job.
  • 64. Protein synthesis • Cells are capable of synthesizing new proteins, which are essential for the modulation and maintenance of cellular activities. This process involves the formation of new protein molecules from amino acid building blocks based on information encoded in DNA/RNA. Protein synthesis generally consists of two major steps: transcription and translation.
  • 65. • Transcription is the process where genetic information in DNA is used to produce a complementary RNA strand. This RNA strand is then processed to give messenger RNA (mRNA), which is free to migrate through the cell. mRNA molecules bind to protein-RNA complexes called ribosomes located in the cytosol.
  • 66. Movement or motility • Cells can move during many processes: such as wound healing, the immune response and cancer metastasis. For wound healing to occur, white blood cells and cells that ingest bacteria move to the wound site to kill the microorganisms that cause infection. At the same time fibroblasts (connective tissue cells) move there to remodel damaged structures.
  • 67. •In the case of tumor development, cells from a primary tumor move away and spread to other parts of the body. Cell motility involves many receptors, cross linking, bundling, binding, adhesion, motor and other proteins.
  • 68. • The process is divided into three steps – protrusion of the leading edge of the cell, adhesion of the leading edge and de-adhesion at the cell body and rear, and cytoskeletal contraction to pull the cell forward. Each step is driven by physical forces generated by unique segments of the cytoskeleton.
  • 69. Presented by - Anushka Ninama Class- VIII th