1. DRUG ACTING ON THE
RESPIRATORY SYSTEM

2. BRONCHODILATORS
• Relax the smooth muscle of the tracheobronchial tree.
• This allows an increase in the opening of the
bronchioles and alveolar ducts, which decreases the
resistance to airflow into the alveolar sacs
• Asthma and bronchitis cause reversible obstruction of
the airways.
• The airway constriction associated with emphysema is
somewhat reversible depending on the severity and
duration of the disease.
• The primary bronchodilators used in the treatment of
airway-obstructive diseases include beta-adrenergic
agents

3. Albuterol sulfate (salbutamol sulfate)
Action
• Relaxes smooth muscle by stimulation beta2
receptor, thereby causing bronchodilation and
vasodilation.

4. indication
• To prevent and relieve broncho spasm in
patient with reversible obstructive airway
disease

5. Side effects to expect
• Gastrointestinal upset
• Nausea and vomiting

6. expectorant
Example
• Robitussin
• Potassium iodide

7. action
• Acts by enhancing the output of respiratory
tract fluid. The increase flow of
secretion, decreases mucus viscosity and
promotes cilliary action. Non productive
cough, as well as to remove mucus plugs from
respiratory.

8. Side effects
• Gastrointestinal upset
• Nausea and vomiting
• Development on side effect are rare

9. antitussive
Action/uses
• Action suppressant, act by suppressing the
cough center in the brain.
• Are use when the patient has bothersome
dry, hacking, non productive cough.
• Not stop the cough frequently but decrease
the frequency of cough and suppress the
severe spasm that prevent adequate rest at
night.

10. examples
• Codiene
• Dextromethopan
• diphenhydramide

11. Side effects
• Drowsiness
• constipation