1. Fluid Therapy Overview and Abbott Animal Health Fluid Therapy Products FLU-229 January 2010 ©2010 Abbott Laboratories

2. The Goal of Fluid Therapy Fluid Therapy is used to restore the volume and composition of body fluids to normal with respect to water / electrolyte balance in order to ensure proper perfusion of tissues and organs FLU-229 January 2010 ©2010 Abbott Laboratories

4. Blood Flow (Cardiac Output)

5. Cellular Delivery

6. Hydration

7. Correct Fluid VolumesFLU-229 January 2010 ©2010 Abbott Laboratories

8. Fluid Therapy is the most under-used therapy in veterinary medicine… WHY? FLU-229 January 2010 ©2010 Abbott Laboratories

10. Solutions types

11. Routes of administration

12. RatesFLU-229 January 2010 ©2010 Abbott Laboratories

14. Replace losses of fluids and blood

16. It’s All About Tissue Perfusion What is perfusion? The process by which blood carries nutrients to and waste products from body tissues Perfusion depends on many body compensatory responses, but also on the administration of appropriate fluid volumes to maintain vascular volume FLU-229 January 2010 ©2010 Abbott Laboratories

17. Body Functions Involved with Tissue Perfusion Renal function– The nephrons filter all of the liquid passing through, removing some particles, reabsorbing some of the fluid and excreting the rest. The kidneys regulate the correct fluid balance and electrolyte levels in the body Cardiac function– Proper fluid balance maintains the stroke volume in the heart, or the amount of blood the ventricle pumps out with each beat. If the fluid volume is low then cardiac output is low, decreasing blood pressure Brain function– With proper blood pressure the brain receives the oxygen it needs to maintain optimal functioning Repeated or extensive loss of tissue perfusion causes irreparable damage in those organs FLU-229 January 2010 ©2010 Abbott Laboratories

18. More on the Importance of Fluid Therapy I.V. Fluid Therapy supports recovery and healing in order to restore normal body functions which have been disrupted by illness, dehydration, trauma, blood loss or surgery When tissue perfusion is inadequate, the balance is upset; then cells, organs, and systems will not perform well; health and recovery could be impaired FLU-229 January 2010 ©2010 Abbott Laboratories

19. More on the Importance of Fluid Therapy Long term, the lack of fluids and recurring deprivation of perfusion, can cause organ dysfunction, damage and systemic failure which could lead to premature death The depletion of adequate fluids during trauma associated with an injury, extreme illness or surgery, could lead to organ failure and sudden death FLU-229 January 2010 ©2010 Abbott Laboratories

20. Components of an I.V. System SECONDARY BAG HANGER CONVERTIBLE PIERCING PIN PRIMARY SET DRIP CHAMBER PRIMARY BAG CLAMP LOCKING BLUNT CANNULA PIGGYBACK SET SECONDARY SET INJECTION PORT OPTIONAL LUER LOCK T-CONNECTOR CATHETER FLU-229 January 2010 ©2010 Abbott Laboratories

21. Fluid Therapy Products from Abbott Animal Health FLU-229 January 2010 ©2010 Abbott Laboratories

23. I.V. Solutions * All products are human labeled except the 3L LRS and Normosol which are identified as vet labeled. Normosol® is a registered trademark of Hospira, Inc. FLU-229 January 2010 ©2010 Abbott Laboratories

24. I.V. Sets Abbott Animal Health’s Fluid Therapy product line includes a selection of I.V. Sets: Primary Sets Secondary Sets Specialty Sets Extension Sets Accessories FLU-229 January 2010 ©2010 Abbott Laboratories

25. I.V. Catheters Abbott provides several catheter types including: Abbocath-T® peripheral catheter for short-term use Subclavian Abbocath-T® jugular and central catheter for long-term use Winged infusion sets for short-term infusion and blood draws Abbocath-T® is a registered trademark of Hospira, Inc. FLU-229 January 2010 ©2010 Abbott Laboratories

26. Needle Free (MicroCLAVE®)Products and Accessories Increase Practice Efficiency: Decrease needle use Easy connection / disconnection (e.g. for easy dog walking or mobility) Reduce the use of tape and other locking devices Reduces Risk of Contamination: Silicon seal creates a closed fluid pathway reducing the risk of external contamination Safe for use with blood, chemotherapy agents and lipid products Decreased risk of infection from the venous access site Raise the Standard of Care: Facilitates precision delivery of small fluid volumes Sterile delivery of I.V. solutions, anesthetic drugs, blood and chemotherapy agents DEHP free MicroCLAVE® is a registered trademark of ICU Medical, Inc. FLU-229 January 2010 ©2010 Abbott Laboratories

27. Needle Free (MicroCLAVE®)Products and Accessories 7” Smallbore, Largebore T-connector, Injection site, Slip luer, Non-DEHP tubing 7” Smallbore, Largebore T-connector, Injection site, luer lock, Non-DEHP tubing Male Adapter Plug 100” primary set, 15 drops/mL, 2 MicroCLAVE® Injection ports, back-check valve, luer lock, Non-DEHP tubing Multi-dose Vial Adapter CLAVE® Bag Access Device MicroCLAVE® is a registered trademark of ICU Medical, Inc. FLU-229 January 2010 ©2010 Abbott Laboratories

28. Products and Support Look to Abbott Animal Health for a full-line of Fluid Therapy products, and … Education and support for your practice The new Abbott Animal Health CE system provides extensive and interactive training for your team (www.AbbottAnimalHealthCE.com) Ask an Abbott representative how to get your free log-in to this valuable resource FLU-229 January 2010 ©2010 Abbott Laboratories

29. To learn more about Abbott Animal Health, our dedication to animal health excellence and our quality products, contact your local Abbott sales representative or Customer Service at 888-299-7416 or visit www.AbbottAnimalHealth.com FLU-229 January 2010 ©2010 Abbott Laboratories