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Attribution: University of Michigan Medical School, Department of Microbiology
and Immunology

License: Unless otherwise noted, this material is made available under the terms
of the Creative Commons Attribution–Noncommercial–Share Alike 3.0
License: http://creativecommons.org/licenses/by-nc-sa/3.0/ 
    We have reviewed this material in accordance with U.S. Copyright Law and have tried to maximize your
    ability to use, share, and adapt it. The citation key on the following slide provides information about how you
    may share and adapt this material.

    Copyright holders of content included in this material should contact open.michigan@umich.edu with any
    questions, corrections, or clarification regarding the use of content.

    For more information about how to cite these materials visit http://open.umich.edu/education/about/terms-of-use.

    Any medical information in this material is intended to inform and educate and is not a tool for self-diagnosis
    or a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional. Please
    speak to your physician if you have questions about your medical condition.

    Viewer discretion is advised: Some medical content is graphic and may not be suitable for all viewers.
Citation Key
                           for more information see: http://open.umich.edu/wiki/CitationPolicy



Use + Share + Adapt
   { Content the copyright holder, author, or law permits you to use, share and adapt. }
                Public Domain – Government: Works that are produced by the U.S. Government. (USC 17 § 105)
                Public Domain – Expired: Works that are no longer protected due to an expired copyright term.
                Public Domain – Self Dedicated: Works that a copyright holder has dedicated to the public domain.

                Creative Commons – Zero Waiver

                Creative Commons – Attribution License
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Make Your Own Assessment

 { Content Open.Michigan believes can be used, shared, and adapted because it is ineligible for copyright. }
                Public Domain – Ineligible: Works that are ineligible for copyright protection in the U.S. (USC 17 § 102(b)) *laws in
                your jurisdiction may differ
    { Content Open.Michigan has used under a Fair Use determination. }
                Fair Use: Use of works that is determined to be Fair consistent with the U.S. Copyright Act. (USC 17 § 107) *laws in your
                jurisdiction may differ
                Our determination DOES NOT mean that all uses of this 3rd-party content are Fair Uses and we DO NOT guarantee that
                your use of the content is Fair.
                To use this content you should do your own independent analysis to determine whether or not your use will be Fair.
Multiple Myeloma

              M1 – Immunology Sequence



Winter 2009
Source Undetermined
Source Undetermined
Immunoelectrophoresis

Serum proteins are fractionated in an
electrical field. Separation is by net
charge.
Sample is from a
                      patient with multiple
                      myeloma. Hence,
                      gamma globulin
                      peak is unusually
                      narrow.




Source Undetermined
Janeway. Immunobiology : The Immune System in Health and Disease. Current Biology Ltd./Garland Publishing, Inc. 1997
Bone Marrow Biopsy




Source Undetermined
Additional Source Information
                  for more information see: http://open.umich.edu/wiki/CitationPolicy


Slide 4: Source Undetermined
Slide 5: Source Undetermined
Slide 7: Source Undetermined
Slide 8: Janeway. Immunobiology: The Immune System in Health and Disease. Current Biology Ltd./Garland Publishing, Inc. 1997
Slide 9: Source Undetermined

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02.12.09: Multiple Myeloma

  • 1. Attribution: University of Michigan Medical School, Department of Microbiology and Immunology License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution–Noncommercial–Share Alike 3.0 License: http://creativecommons.org/licenses/by-nc-sa/3.0/ We have reviewed this material in accordance with U.S. Copyright Law and have tried to maximize your ability to use, share, and adapt it. The citation key on the following slide provides information about how you may share and adapt this material. Copyright holders of content included in this material should contact open.michigan@umich.edu with any questions, corrections, or clarification regarding the use of content. For more information about how to cite these materials visit http://open.umich.edu/education/about/terms-of-use. Any medical information in this material is intended to inform and educate and is not a tool for self-diagnosis or a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional. Please speak to your physician if you have questions about your medical condition. Viewer discretion is advised: Some medical content is graphic and may not be suitable for all viewers.
  • 2. Citation Key for more information see: http://open.umich.edu/wiki/CitationPolicy Use + Share + Adapt { Content the copyright holder, author, or law permits you to use, share and adapt. } Public Domain – Government: Works that are produced by the U.S. Government. (USC 17 § 105) Public Domain – Expired: Works that are no longer protected due to an expired copyright term. Public Domain – Self Dedicated: Works that a copyright holder has dedicated to the public domain. Creative Commons – Zero Waiver Creative Commons – Attribution License Creative Commons – Attribution Share Alike License Creative Commons – Attribution Noncommercial License Creative Commons – Attribution Noncommercial Share Alike License GNU – Free Documentation License Make Your Own Assessment { Content Open.Michigan believes can be used, shared, and adapted because it is ineligible for copyright. } Public Domain – Ineligible: Works that are ineligible for copyright protection in the U.S. (USC 17 § 102(b)) *laws in your jurisdiction may differ { Content Open.Michigan has used under a Fair Use determination. } Fair Use: Use of works that is determined to be Fair consistent with the U.S. Copyright Act. (USC 17 § 107) *laws in your jurisdiction may differ Our determination DOES NOT mean that all uses of this 3rd-party content are Fair Uses and we DO NOT guarantee that your use of the content is Fair. To use this content you should do your own independent analysis to determine whether or not your use will be Fair.
  • 3. Multiple Myeloma M1 – Immunology Sequence Winter 2009
  • 6. Immunoelectrophoresis Serum proteins are fractionated in an electrical field. Separation is by net charge.
  • 7. Sample is from a patient with multiple myeloma. Hence, gamma globulin peak is unusually narrow. Source Undetermined
  • 8. Janeway. Immunobiology : The Immune System in Health and Disease. Current Biology Ltd./Garland Publishing, Inc. 1997
  • 10. Additional Source Information for more information see: http://open.umich.edu/wiki/CitationPolicy Slide 4: Source Undetermined Slide 5: Source Undetermined Slide 7: Source Undetermined Slide 8: Janeway. Immunobiology: The Immune System in Health and Disease. Current Biology Ltd./Garland Publishing, Inc. 1997 Slide 9: Source Undetermined