Brown: Is the Peer Review Journal Dead?

•Transferir como PPTX, PDF•

4 gostaram•2,297 visualizações

SMACC Conference

Tony Brown's emotive expose on the bias of medical research and publication. The flaws in our current paradigms.

Saúde e medicina Tecnologia

Is the Peer Review Journal Dead?
Professor Tony Brown
Senior Staff Specialist
Department of Emergency Medicine
Royal Brisbane and Women’s Hospital

Competing Interests Declaration
Professor Tony Brown
Educational / research funding:
Astra Zeneca, Boehringer Ingelheim, Roche,
Sanofi-Aventis, Shire.
Avant.

550,000
> 1 / minute
>150 this morning
> 5,600
(MedlineTM)

Is the Peer Review Journal Dead?
Aims
• What are journals for ?
• What do they do ?
• Who benefits ?
• What are the problems ?
• What are the alternatives ?

What are journals for ?
• Registration
• Certification
• Awareness
• Archiving

What do they do ?
• Online submission
• Peer review
• Editorial decision
• Production
• Publication

Who benefits ?
• Author
• Publisher
• Editor / peer reviewers

What are the problems?
• Peer review
• Most papers are rubbish
• Research hijacked
• Restricted full-text access

What are the problems?
Peer review
“Slow, expensive, ineffective, a lottery, biased,
incapable of detecting fraud and prone to
abuse”
Smith R. BMJ 2004;329:242-4

What are the problems?
Most papers are rubbish
• “Words on paper rarely lead directly to change
– and thank goodness they don’t, considering
the rubbish that journals often publish”.
Smith R. BMJ 2004;329:242-4
• Few trials are valid and relevant ( <1% – 7% )
Haynes RB. ACP J Club 1993;119:A22-A23
Scott I, Glaziou P. Med J Aust 2012;197:374-8

What are the problems?
Research hijacked
Radcliffe Publishing
2013
Harper Collins 2013

What are the problems?
Restricted full-text access
$24 billion
biomedical publishing industry

What are the alternatives?
• Release ALL data / publish negative trials
• Focus on the reader
• Post publication review
• ‘publish then filter’
• rating systems / Web 2.0 tools / crowdsourcing
• Educational / translational focus …

What are the alternatives?
Educational / translational focus
Websites Blog posts
Case studies Teaching videos
Podcasts Elearning modules
Apps
ALL informed by the best literature

Is the Peer Review Journal Dead?
Conclusions
• Not yet – but smelling badly !
• Return the focus back onto the reader
• Expect and embrace all forms of
post publication review
• Focus on education / translation

Is the Peer Review Journal Dead?
Conclusions
• Not yet – but smelling badly …
• Return the focus back onto the reader
• Expect / embrace post publication review
• Focus on education / translation
• EXCEPTION !
Emerg Med Australas 2014; 26 (1). Feb issue

Mais conteúdo relacionado

Semelhante a Brown: Is the Peer Review Journal Dead?

Understanding scientific peer review

Samir Haffar

Getting your Rural Health Research Published

Melissa Storey

BioMed Central, an editorial perspective

BioMedCentral

What Should PCORI Study?

Patient-Centered Outcomes Research Institute

2012 10-16 gettingpublishedslideshare

kathwoolf

Andre Tomlin - Using social media to communicate the findings of Cochrane rev...

André Tomlin

Publishing Connect NUI Galway - 31st Jan 2017

Michaela Kurschildgen

Publish or Perish - A guide to submitting papers for peer-reviewed publication

Ian Brown

Write for the AORN Journal

Association of periOperative Registered Nurses (AORN)

Personal strategies for improving your ref publications

azlina kamaruddin

Peer review is the most widely accepted model for setting a threshold of published scholarly material. With the move to digital publishing, it has come under attack with suggestions that it is 'broken', overloading reviewers and possibly no longer fit for purpose. This presentation discusses the challenges for peer review and some emerging new models. Ultimately, we may need to take a step back to ask what peer review is for and how these aims can best be achieved. Video available at https://www.youtube.com/watch?v=7YMla0Uc5ZE&x-yt-ts=1422327029&x-yt-cl=84838260

Approaches to Peer Review

Martyn Rittman

Predatory Publishing

Kristin Kroger

WCACS2017 SOME.pptx

WSACS

Evaluating medical evidence for journalists

Ivan Oransky

What is health chp 1

spiller1

CNUDST Workshops -Why quality articles

Bessem Aamira

Evidence based practice

Aslam Alkadhimi

Publishing Tips from the Field Nathan Grills

Christian Connections for International Health

Objectives: 1. To give the rationale why staying current on the medical literature is important for patient care, and to explain why this is difficult in practice; 2. To give an overview over study types and forms of bias and other common methodological pitfalls; and 3. To introduce practical ways on how one can 1) get a quick overview over a given clinical areas and 2) stay up-to-date on the hospital medicine literature.

Interpreting the Medical Literature

Harvard Medical School, LMU Munich

Pharmacology 502 fall 2022.pptx

Kara Gavin

Semelhante a Brown: Is the Peer Review Journal Dead? (20)

Understanding scientific peer review

Getting your Rural Health Research Published

BioMed Central, an editorial perspective

What Should PCORI Study?

2012 10-16 gettingpublishedslideshare

Andre Tomlin - Using social media to communicate the findings of Cochrane rev...

Publishing Connect NUI Galway - 31st Jan 2017

Publish or Perish - A guide to submitting papers for peer-reviewed publication

Write for the AORN Journal

Personal strategies for improving your ref publications

Approaches to Peer Review

Predatory Publishing

WCACS2017 SOME.pptx

Evaluating medical evidence for journalists

What is health chp 1

CNUDST Workshops -Why quality articles

Evidence based practice

Publishing Tips from the Field Nathan Grills

Interpreting the Medical Literature

Pharmacology 502 fall 2022.pptx

Mais de SMACC Conference

Precision Medicine in Acute Brain Injury

SMACC Conference

CORTICAL SPREADING DEPOLARISATION IN NEUROLOGICAL DISEASE – AN INTRODUCTION By Toby Jeffcote Cortical spreading depolarization (CSD) is a spreading loss of ion homeostasis, altered vascular response, change in synaptic architecture, and subsequent depression in electrical activity following an inciting neurological injury. It was first described by Leão in 1944, a disturbance in neuronal electrophysiology has since been demonstrated in a number of animal studies, and recently a few human studies that examine the occurrence of this depolarizing phenomenon in the setting of a variety of pathological states, including migraines, cerebrovascular accidents, epilepsy, intracranial hemorrhages, and traumatic brain injuries. The onset of CSD has been demonstrated experimentally following a disruption in the neuronal environment leading to glutamate-induced toxicity. This initial event leads to pathological changes in the activity of ion channels that maintain membrane potential. Recovery mechanisms such as sodium-potassium pumps that aim to restore homeostasis fail, leading to osmolar shifts of fluid, swelling of the neuron, and ultimately a measurable depression in cortical activity that spreads in the order of millimeters per minute. Equally important is the resulting change in vascular response. In healthy tissue, increased electrical activity is coupled with release of vasodilatory factors such as nitric oxide and arachidonic acid metabolites that increase local blood flow to meet increased energy expenditure. In damaged tissue, not only is the restorative vascular response lacking but a vasoconstrictive response is promoted and the ischemia that follows adds to the severity of the initial injury. Tissue threatened by this ischemic response is then at elevated risk for CSD propagation and falls into a vicious cycle of electrical and hemodynamic disturbance. Efforts have been made to halt this spreading cortical depression using N-methyl-D-aspartate receptor antagonists and other ion channel blockers to minimize the damaging effects of CSD that can persist long after the triggering insult.

CSD by Jeffcote Coda 22.pdf

SMACC Conference

Subdural Haemorrhage and MMA embolisation

SMACC Conference

Andy Neill - More neuroanatomy pearls for neurocritical care

SMACC Conference

Andrew Udy talks about Brain Tissue Oxygen Monitoring: It’s Not What You’ve Got It’s What You Do With It The BONANZA Trial Andrew Udy talks about the ongoing BONANZA Trial which is assessing whether an algorithm that incorporates both ICP and brain tissue oxygen (PbTO2) can improve outcomes after traumatic brain injury (TBI). Like with all monitoring, how the PbTO2 is interpreted and managed is critical and the devil is in the detail! More on BONANZA here More on BOOST3 here

The BONANZA Trial and PbTO2 Monitoring

SMACC Conference

Dilating the Dogma of Vasospasm

SMACC Conference

EVD Tips and Tricks

SMACC Conference

Part 2 of a debate over the classification of TBI. Andrew Udy then argues that this classification is fundamentally flawed. He discusses the issues with the Glasgow Coma Scale, and therefore the follow-on issues in TBI classification, including all the confounders to the GCS, the issues with timing of the score as well as GCS not taking baseline function or specifics subtypes of TBI into account. He makes teh argument that biomarkers may better categorise the diffuse entity we call TBI.

There is no such thing as mild, moderate and severe TBI - by Andrew Udy

SMACC Conference

Andrew Chow, Intensivist with a neurosurgical background, argues that the current categorisation system for traumatic brain injury (TBI) works, and makes sense! He tackles us through the history of this system, and why it’s important to differentiate different types of TBI. The arguments in favour of this categorisation include the consistency and benefits of a universal language, the implications for triage and management, and the fact that this system has been endorsed by all major organisations

TBI Debate - Mild, moderate and severe categories work

SMACC Conference

Dr Nick Little is an experienced Neurosurgeon who's looked after patients with traumatic brain injury for his whole career. Here he discusses the difficulties of prognostication following traumatic brain injury (TBI). He talks about the statistics of outcomes following mild, moderate and severe TBI and then goes on to tackle the harder topic of how we try to work out what an individual would want if they knew the spectrum of outcomes that they may face. The issues with the clinical examination findings we use to prognosticate are covered, as well as which imaging findings he finds most helpful. He also mentions the difficulties with current prognostic calculators.

TBI: when to stop and when to give time

SMACC Conference

Historically, when it came to brain injury, ketamine had a bad rap. Much of that dogma was dispelled in the last decade, and ketamine is now frequently used as an induction agent in acute brain injury, especially traumatic brain injury, due to it’s favorable effects on haemodynamics. However a new application of ketamine is now being explored - whether ketamine may be able to reduce secondary brain injury.

Ketamine in Brain Injury by Toby Jeffcote

SMACC Conference

20 million people around the world are living with a spinal cord injury (SCI). The medical issues they develop over the years differ to any other patient cohort. These complications include autonomic dysreflexia, management of pressure areas, specific infections, nuanced peri-operative care and highly specific issues such as baclofen pump management and syringomyelia Do look at the NeuroResus section on this and listen to Spinal Rehab Specialist Bonne Lee talk about this side of SCI care. Keywords SCI, spinal, spinal cord injury, autonomic dysreflexia, pressure areas, infection, peri-operative care, baclofen pump, syringomyelia, chronic SCI, spinal trauma, spinal rehab, incomplete SCI

Managing Complications of Chronic SCI by Bonne Lee

SMACC Conference

Tania is a neurologist and epileptologist with expertise in continuous EEG (cEEG) and status epilepticus (SE). This talk covers what a seizure is, what status is, including focal and generalised status epilepticus. So why do we do cEEGs for patients with suspected SE? To confirm the diagnosis To see if patient just post ictal or still seizing To establish that the clinical and electric seizures have stopped To see if burst suppression is achieved To exclude other differential diagnoses She makes a good argument for why cEEG is such an important tool in managing SE. In the questions after the talk, the issue of availability of cEEG in the Australian setting was discussed. Limited montage EEGs are discussed including their pros and cons.

EEG and Status Eplilepticus by Tania Farrar

SMACC Conference

Stuart Browne is a Neuro Rehab specialist from Sydney. These slides accompany a talk he gave at the Brian Symposium in 2023. He discusses what "severe disability" really means. Severe disability is more common than many realise - about 6% of the Australian population. Stuart discusses how health is more than simply physical recovery and how it is a multidimensional construct. He covers how permanent disability doesn't necessarily equate to a poor quality of life. He also discusses the long timespan of recovery, which is often much longer than appreciated. He specifically discusses "Locked-in Syndrome" and how the survivors have surprisingly positive self-reported health-related quality of life and well-being. Stuart also covers how severely disabled people face various forms of discrimination.

Browne Neuro symposium.pptx

SMACC Conference

Paediatric Stroke by Shree Basu

SMACC Conference

After spinal cord injury (SCI), there aren’t many interventions we have available that actually make a difference. Augmenting blood pressure to increase spinal cord perfusion pressure is an attractive concept that may improve neurological outcomes following SCI. We know that hypotension can make SCI worse. Clinical studies looking at blood pressure augmentation are mostly old, retrospective and flawed in various ways. Aiming for a MAP of > 85 for 5-7 days is recommended by guidelines but why this pressure and duration are good questions. Hypertensive therapy is relatively safe and easy to implement but not without risk. Tessa discusses the pros and cons, how this is managed practically and what the future may hold in this area.

Hypertensing Spinal Cord Injury - gold standard or wacky?

SMACC Conference

Mark Weedon takes us through the increasingly utilised concept of an optimal cerebral perfusion pressure (CPPopt) for each unique patient. He discusses the background to CPPopt, including intrcranial pressure (ICP), the Monroe Kelly hypothesis, neurovascular coupling, and cerebral autoregulation in health and following brain injury. He shows how intracranial pressure is affected by intracranial compliance and how this affects ICP waveforms. Cerebral perfusion pressure in relation to the Brain Trauma Foundation guidelines is covered including management of elevated ICP (EICP). The currently recommended tiered approach to managing cerebral perfusion pressure and EICP is mentioned citing recent guidelines. He uses a clinical case of a TBI to illustrate how the CPPopt can be ascertained and used to guide therapy, including the easy to perform “MAP Challenge”. Mark also describes the Pressure Reactivity Index (PRx) and how it can be used as a target for therapy. Finally, he covers the exciting results of the preliminary COGiTATE pilot study.

Optimal Cerebral Perfusion Pressure

SMACC Conference

The Power of Words - Death and Language.ppt

SMACC Conference

Appropriate use of antimicrobials is primarily a patient safety issue, and is the key aim of an effective antimicrobial stewardship program. We discuss the challenges in the management of a patient with sepsis, and how decision-making is usually done in the absence of effective diagnostics. Time dependent protocols and the knowledge that undertreatment of a patient with sepsis will lead to poor outcomes will lead to prescribing that may be driven by fear. Antimicrobial resistance is associated with over-use of antimicrobials but is usually not the immediate concern. Antimicrobial stewardship programs should work closely with sepsis teams to ensure that sepsis pathways are implemented across the whole hospital, and that key principles of judicious use are embedded within the clinical pathway.

Sepsis and Antimicrobial Stewardship - Two Sides of the Same Coin

SMACC Conference

Being able to prognosticate in the aftermath of a traumatic brain injury (TBI) is important as it assists with counselling patients and families. Moreover, it helps rationally allocate healthcare resources. However, due to the heterogenous nature of TBI and variable pre brain injury patient factors and post brain injury course, this has proven to be a difficult task. Large cohort studies have enabled improved accuracy in the prediction of 6 month mortality and unfavourable outcome. Furthermore, many of the factors that contribute to long-term outcome have also emerged. However, it is not yet possible to use them in prediction algorithms or mathematical models. There is emerging evidence that pre injury psychosocial and demographic factors may be of more relevance than injury severity. Moreover, that 'outcome' becomes increasingly subjective and complex as the post injury duration increases. We end with three brief vignettes which highlight the fraught nature of long term outcome prediction.

Brain injury outcomes and predictors

SMACC Conference

Mais de SMACC Conference (20)

Precision Medicine in Acute Brain Injury

CSD by Jeffcote Coda 22.pdf

Subdural Haemorrhage and MMA embolisation

Andy Neill - More neuroanatomy pearls for neurocritical care

The BONANZA Trial and PbTO2 Monitoring

Dilating the Dogma of Vasospasm

EVD Tips and Tricks

There is no such thing as mild, moderate and severe TBI - by Andrew Udy

TBI Debate - Mild, moderate and severe categories work

TBI: when to stop and when to give time

Ketamine in Brain Injury by Toby Jeffcote

Managing Complications of Chronic SCI by Bonne Lee

EEG and Status Eplilepticus by Tania Farrar

Browne Neuro symposium.pptx

Paediatric Stroke by Shree Basu

Hypertensing Spinal Cord Injury - gold standard or wacky?

Optimal Cerebral Perfusion Pressure

The Power of Words - Death and Language.ppt

Sepsis and Antimicrobial Stewardship - Two Sides of the Same Coin

Brain injury outcomes and predictors

Último

Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Massage and Pleasant Why you Choose Us- +91-6378878445 Bangalore Escort Service includes providing maximum physical satisfaction to their clients as well as engaging conversation that keeps your time enjoyable and entertaining. Plus they look fabulously elegant; making an impressionable I Have Extremely Beautiful Broad Minded Cute Sexy & Hot Call Girls and Escorts, We Are Located in 3* 4* 5* Hotels. Safe & Secure High Class Services Affordable Rate 100% Satisfaction, Unlimited Enjoyment. Any Time for Model/Teens Escort in Delhi High class luxury and premium escorts agency. CALL US High Class Luxury and Premium Escort Service We Provide Well Educated,Royal Class Female,High-Class Escort Service Offering a Top High Class Escort Service In The & Several Nearby All Places of $L16

Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...

tanya dube

Independent Call Girls Service Mohali Sector 116 | 6367187148 | Call Girl Service Number Mohali Call Girls Mohali Just Call 6367187148 Top Class Call Girl Service Available ★ CALL US High Class Luxury and Premium Escort Service We Provide Well Educated,Royal Class Female,High-Class Escort Service Offering a Top High Class Escort Service In The & Several Nearby All Places of . ★ To Enjoy With Hot and Sexy Girls . ★ We Are Providing :- • 3* #S07 5* 7*Hotels Service in • Hygienic Full AC Neat and Clean Rooms Avail. • Daily New Escorts Staff Available • Minimum to Maximum Range Available. Our escort service •BJ (Blowjob) •FK (French kissing) •Kissing with tongue •O-Level (Oral sex) •Long Silky Brown Hair •69 (69 sex) •A-Level (5 start Escort) •Dating

Independent Call Girls Service Mohali Sector 116 | 6367187148 | Call Girl Ser...

karishmasinghjnh

Jogeshwari ! Call Girls Service Mumbai - 450+ Call Girl Cash Payment 9004268417 Neha Thakur Booking Contact Details WhatsApp Chat: +91-9004268417 Mumbai Escort Service includes providing maximum physical satisfaction to their clients as well as engaging conversation that keeps your time enjoyable and entertaining. Plus they look fabulously elegant;$S2 making an impressionable. Independent Escorts Mumbai understands the value of confidentiality and discretion - they will go the extra mile to meet your needs. Simply contact them via text messaging or through their online profiles; they'd be more than delighted to accommodate any request or arrange a romantic date or fun-filled night together. We provide - Flexibility Choices and options Lists of many beauty fantasies Turn your dream into reality Perfect companionship Cheap and convenient In-call and Out-call services And many more.

Jogeshwari ! Call Girls Service Mumbai - 450+ Call Girl Cash Payment 90042684...

Anamika Rawat

Call Girls Kolkata Kalikapur 💯Call Us 🔝 8005736733 🔝 💃 Top Class Call Girl Service Available Call Mrs Leela Ji +91-8005736733 We offer all types of girls of your choice with space. Our escorts are fully cooperative and understand your needs. All types of call girls like Housewives, College girls,#J11 Russian girls, Muslim girls, Afghani girls, Bengali girls, Working girls, south Indian girls, Punjabi girls, etc. In-Call: — You Can Reach At Our Place in Kolkata Our place Which Is Very Clean Hygienic 100% safe Accommodation. Out-Call: — Service for Out Call You have To Come Pick The Girl From My Place We Also Provide Door-Step Services Hygienic: — Full Ac Neat And Clean Rooms Available In Hotel 24 * 7 Hrs In Kolkata C010524HD Our Services and Rates: – One Shot — 2500/in call (time ½ hour), 5000/out call Two shot with one girl — 5000/in call (time 1 hour), 6000/out call Body to body massage with sex- 3000/in call (time 1 hour) full night for one person– 8000/in call, 10000/out call (shot limit 4 shot) We are available 24*7 all days of the year Call us — 8005736733 !! Thank you for Visiting.

Call Girls Kolkata Kalikapur 💯Call Us 🔝 8005736733 🔝 💃 Top Class Call Girl Se...

Namrata Singh

Coimbatore Call Girls in Coimbatore 7427069034 genuine Escort Service Girl 100% verified Why you Choose Us- +91-7427069034 Escort Service includes providing maximum physical satisfaction to their clients as well as engaging conversation that keeps your time enjoyable and entertaining. Plus they look fabulously elegant; making an impressionable I Have Extremely Beautiful Broad Minded Cute Sexy & Hot Call Girls and Escorts, We Are Located in 3* 4* 5* Hotels. Safe & Secure High Class Services Affordable Rate 100% Satisfaction, Unlimited Enjoyment. Any Time for Model/Teens Escort in Delhi High class luxury and premium escorts agency. ★ CALL US High Class Luxury and Premium Escort Service We Provide Well Educated,Royal Class Female,High-Class Escort Service Offering a Top High Class Escort Service In The & Several Nearby All Places of . ★ To Enjoy With Hot and Sexy Girls . ★ We Are Providing :- • 3* 5* 7*Hotels Service • Hygienic Full AC Neat and Clean Rooms Avail. • Daily New Escorts Staff Available • Minimum to Maximum Range Available. Our escort service •BJ (Blowjob) •FK (French kissing) •Kissing with tongue •O-Level (Oral sex) •Long Silky Brown Hair •69 (69 sex) •A-Level (5 start Escort) •Dating 03-May(Ast)

Coimbatore Call Girls in Coimbatore 7427069034 genuine Escort Service Girl 10...

chennailover

Top Quality Call Girl Service Kalyanpur 6378878445 Available Call Girls Any Time Call Mr Chirag Ji +91-6378878445 We offer all types of girls of your choice with space. Our escorts are fully cooperative and understand your needs. All types of call girls like Housewives, College girls, Russian girls, Muslim girls, Afghani girls, Bengali girls, Working girls, south Indian girls, Punjabi girls, etc. In-Call: — You Can Reach At Our Place in Our place Which Is Very Clean Hygienic 100% safe Accommodation. Out-Call: — Service for Out Call You have To Come Pick The Girl From My Place We Also Provide Door-Step Services Hygienic: — Full Ac Neat And Clean Rooms Available In Hotel 24 * 7 Hrs In 03-May-2024 (chd) Our Services and Rates: – One Shot — 2500/in call (time ½ hour), 5000/out call Two shot with one girl — 5000/in call (time 1 hour), 6000/out call Body to body massage with sex- 3000/in call (time 1 hour) full night for one person– 8000/in call, 10000/out call (shot limit 4 shot) We are available 24*7 all days of the year Call us — 6378878445 !! Thank you for Visiting.

Top Quality Call Girl Service Kalyanpur 6378878445 Available Call Girls Any Time

Call Girls Delhi

Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 Star Hotel Service Available Booking Contact Details WhatsApp Chat: +91-8617370543 Patna Escort Service includes providing maximum physical satisfaction to their clients as well as engaging conversation that keeps your time enjoyable and entertaining. Plus they look fabulously elegant; making an impressionable Independent Escorts Patna understands the value of confidentiality and discretion - they will go the extra mile to meet your needs. Simply contact them via text messaging or through their online profiles; they'd be more than delighted to accommodate any request or arrange a romantic date or fun-filled night together. We provide - Flexibility Choices and options Lists of many beauty fantasies Turn your dream into reality Perfect companionship Cheap and convenient In-call and Out-call services And many more.

Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...

Dipal Arora

Call Girls Rishikesh Just Call 9667172968 Top Class Call Girl Service Available Easy & Fast Booking Procedure Of Rishikesh Escorts Call girls are available to provide the quality essentialness that will ease away life's tensions. Rishikesh Escorts are regular companions of elite gentlemen. It is possible to take them to places they would never have dreamed of visiting otherwise. Their portfolios can be found online through escort agencies; they maintain themselves to look attractive by visiting salons and spas regularly. EXCITING OPTIONS AVAILABLE AT OUR INDEPENDENT ESCORTS Candlelight dinner Evening date Night clubs or parties Hotels or your flats Business trip Business party Stripping party Rishikesh Escort Service are skilled at performing wild anal sex, deep throat sex and cum eating - ideal for satisfying all your sexual needs and playing any game possible. Professional assistants are readily available and ready to assist in any situation - romantic date or solo outing. They can accompany you to restaurants or bars where their presence will surely leave an impression with their beautiful appearances and striking personalities.

Call Girls Rishikesh Just Call 9667172968 Top Class Call Girl Service Available

perfect solution

Andheri East ) Call Girls in Mumbai Phone No 9004268417 Elite Escort Service Available 24/7 Hire Booking Contact Details WhatsApp Chat: +91-9004268417 Mumbai Escort Service includes providing maximum physical satisfaction to their clients as well as engaging conversation that keeps your time enjoyable and entertaining. Plus they look fabulously elegant;$S2 making an impressionable. Independent Escorts Mumbai understands the value of confidentiality and discretion - they will go the extra mile to meet your needs. Simply contact them via text messaging or through their online profiles; they'd be more than delighted to accommodate any request or arrange a romantic date or fun-filled night together. We provide - Flexibility Choices and options Lists of many beauty fantasies Turn your dream into reality Perfect companionship Cheap and convenient In-call and Out-call services And many more.

Andheri East ) Call Girls in Mumbai Phone No 9004268417 Elite Escort Service ...

Anamika Rawat

Premium Call Girls In Jaipur {8445551418} ❤️VVIP SEEMA Call Girl in Jaipur Rajasthan Booking Details Are here 05-May-2024( Mj) Click On WhatsApp Chat +91-8445551418 Jaipur Escorts Make You Feel Like Royalty Jaipur Escorts catering to high profile clients are available 24-7 to meet their clients' needs and are also available for dinner dates, business conferences, foreign travel trips and clubbing activities. Their customers are contacted directly through in order to prevent risky situations from developing.is home to some of India's most beautiful women. These girls come highly educated with great backgrounds; furthermore they are extremely beautiful and will make you feel like royalty if hired for hours or days! Siya Khan | FOR BOOKING CALL Our All Services :- 1 )★ (Oral to consummation) bjnonCovered 2 )★ Special Massage 3 )★ O-Level (Oral sex) 4 )★ Blow Job; 5 )★ COB (Come On Body) 6 )★. Extraball (Have sex ordinarily) 7 )★ A-Level (5 star escort) 8 )★ Strip-bother 9 )★ BBBJ (Bareback Blowjob) 10 )★ Spending time in my rooms 11 )★ BJ (Blowjob Without a Condom) 12 )★ COF (Come On Face) 13 )★ Completion

Premium Call Girls In Jaipur {8445551418} ❤️VVIP SEEMA Call Girl in Jaipur Ra...

parulsinha

Saket * Call Girls in Delhi - Phone 9711199012 Escorts Service at 6k to 50k along with Free Room Call TO mr Kapoor book Fun:9711199012 Delhi Call ME WHATSAPP RAHUL 9711199012 Provide VIP escort service CALL ME 9711199012 100% satisfaction call 24hrs..% SHORT 2OOO/OUTCALL=2=SHORT=5000 AND Night 7OOO/- FORM INDIAN , NEPALI ,KASMARI MANIPURI HOT GIRLS AND MATURED HOUSE WIFE BOOKING ONLY DECENT GUYS AND GENTLEMAN NO FAKE PERSON FREE HOME SERVICE IN CALL FULL A.C ROOM SERVICE IN SOUTH DELHI satisfied guaranteed (AGE 21) College girls , party girls and also housewife. LOCANTION ~ DELHI,NOIDA,GURGAO NCR Call OR WHATSAPP Kapoor 9711199012 Our Service Available IN All Independent DELHI Escorts SERVICE, 3/5/7 STAR HOTEL SERVICE, in call /Out call Service.24 hrs. * Models * Receptionist, * Air Hostess, * Call Centre Working Girls/Women ans * Hi-tech Co. Girls/Women * House Wife. * College going girls Call ME WHATSAPP RAHUL 9711199012 LOCANTION ~ DELHI,NOIDA,GURGAO Call ME WHATSAPP RAHUL 9711199012 Our Service Available IN All Independent DELHI Escorts SERVICE, 3/5/7 STAR HOTEL SERVICE, in call /Out call Service.24 hrs. * Models * Receptionist, * Air Hostess, * Call Center Working Girls/Women ans * Hi-tech Co. Girls/Women * House Wife. * College going girls Call OR WHATSAPP Kapoor 9711199012 07-05-2024(chd)

Saket * Call Girls in Delhi - Phone 9711199012 Escorts Service at 6k to 50k a...

BhumiSaxena1

Call Girls Service Jaipur {9521753030} ❤️VVIP RIDDHI Call Girl in Jaipur Rajasthan Booking Details Are here 06-May-2024( Mj) Click On WhatsApp Chat +91-9521753030 Jaipur Escorts Make You Feel Like Royalty Jaipur Escorts catering to high profile clients are available 24-7 to meet their clients' needs and are also available for dinner dates, business conferences, foreign travel trips and clubbing activities. Their customers are contacted directly through in order to prevent risky situations from developing.is home to some of India's most beautiful women. These girls come highly educated with great backgrounds; furthermore they are extremely beautiful and will make you feel like royalty if hired for hours or days! Siya Khan | FOR BOOKING CALL Our All Services :- 1 )★ (Oral to consummation) bjnonCovered 2 )★ Special Massage 3 )★ O-Level (Oral sex) 4 )★ Blow Job; 5 )★ COB (Come On Body) 6 )★. Extraball (Have sex ordinarily) 7 )★ A-Level (5 star escort) 8 )★ Strip-bother 9 )★ BBBJ (Bareback Blowjob) 10 )★ Spending time in my rooms 11 )★ BJ (Blowjob Without a Condom) 12 )★ COF (Come On Face) 13 )★ Completion

Call Girls Service Jaipur {9521753030} ❤️VVIP RIDDHI Call Girl in Jaipur Raja...

Sheetaleventcompany

Top Rated Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine Sex Service At Affordable Rate Booking Contact Details WhatsApp Chat: +91-9332606886 Hyderabad Escort Service includes providing maximum physical satisfaction to their clients as well as engaging conversation that keeps your time enjoyable and entertaining. Plus they look fabulously elegant; making an impressionable Independent Escorts Hyderabad understands the value of confidentiality and discretion - they will go the extra mile to meet your needs. Simply contact them via text messaging or through their online profiles; they'd be more than delighted to accommodate any request or arrange a romantic date or fun-filled night together. We provide - Flexibility Choices and options Lists of many beauty fantasies Turn your dream into reality Perfect companionship Cheap and convenient In-call and Out-call services And many more. 02-May(Ast)

Top Rated Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...

chandars293

Call Girls Service Jaipur {8445551418} ❤️VVIP BHAWNA Call Girl in Jaipur Rajasthan Booking Details Are here 05-May-2024( Mj) Click On WhatsApp Chat +91-8445551418 Jaipur Escorts Make You Feel Like Royalty Jaipur Escorts catering to high profile clients are available 24-7 to meet their clients' needs and are also available for dinner dates, business conferences, foreign travel trips and clubbing activities. Their customers are contacted directly through in order to prevent risky situations from developing.is home to some of India's most beautiful women. These girls come highly educated with great backgrounds; furthermore they are extremely beautiful and will make you feel like royalty if hired for hours or days! Siya Khan | FOR BOOKING CALL Our All Services :- 1 )★ (Oral to consummation) bjnonCovered 2 )★ Special Massage 3 )★ O-Level (Oral sex) 4 )★ Blow Job; 5 )★ COB (Come On Body) 6 )★. Extraball (Have sex ordinarily) 7 )★ A-Level (5 star escort) 8 )★ Strip-bother 9 )★ BBBJ (Bareback Blowjob) 10 )★ Spending time in my rooms 11 )★ BJ (Blowjob Without a Condom) 12 )★ COF (Come On Face) 13 )★ Completion

Call Girls Service Jaipur {8445551418} ❤️VVIP BHAWNA Call Girl in Jaipur Raja...

parulsinha

Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl In 5 Star Hotel Service Available Booking Contact Details WhatsApp Chat: +91-8617370543 Guwahati Escort Service includes providing maximum physical satisfaction to their clients as well as engaging conversation that keeps your time enjoyable and entertaining. Plus they look fabulously elegant; making an impressionable Independent Escorts Guwahati understands the value of confidentiality and discretion - they will go the extra mile to meet your needs. Simply contact them via text messaging or through their online profiles; they'd be more than delighted to accommodate any request or arrange a romantic date or fun-filled night together. We provide - Flexibility Choices and options Lists of many beauty fantasies Turn your dream into reality Perfect companionship Cheap and convenient In-call and Out-call services And many more.

Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...

Dipal Arora

Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy Bhabi Ready For Sex At Your Doorstep Booking Contact Details Whatsapp Chat :+91-6297143586 These professional and Call girls in Bangalore can satisfy your every desire - be it sensual massage or an erotic shower, they are always more than willing to meet them. Furthermore, they pay close attention to body language cues to ensure you enjoy every minute spent in their company - both in-call and outcall services are offered. Is an excellent choice for anyone seeking an exciting and thrilling night of fun and excitement The Oberoi, Bengaluru Taj West End The Leela Palace Bengaluru JW Marriott Hotel Bengaluru The Ritz-Carlton, Bangalore Sheraton Grand Bangalore Hotel at Brigade Gateway Conrad Bengaluru ITC Gardenia, Bengaluru Renaissance Bengaluru Race Course Hotel The Lalit Ashok Bangalore 1-may-24

Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...

vidya singh

Call Girls Service Jaipur {9521753030 } ❤️VVIP BHAWNA Call Girl in Jaipur Rajasthan Booking Details Are here 05-May-2024( Mj) Click On WhatsApp Chat +91-9521753030 Jaipur Escorts Make You Feel Like Royalty Jaipur Escorts catering to high profile clients are available 24-7 to meet their clients' needs and are also available for dinner dates, business conferences, foreign travel trips and clubbing activities. Their customers are contacted directly through in order to prevent risky situations from developing.is home to some of India's most beautiful women. These girls come highly educated with great backgrounds; furthermore they are extremely beautiful and will make you feel like royalty if hired for hours or days! Siya Khan | FOR BOOKING CALL Our All Services :- 1 )★ (Oral to consummation) bjnonCovered 2 )★ Special Massage 3 )★ O-Level (Oral sex) 4 )★ Blow Job; 5 )★ COB (Come On Body) 6 )★. Extraball (Have sex ordinarily) 7 )★ A-Level (5 star escort) 8 )★ Strip-bother 9 )★ BBBJ (Bareback Blowjob) 10 )★ Spending time in my rooms 11 )★ BJ (Blowjob Without a Condom) 12 )★ COF (Come On Face) 13 )★ Completion

Call Girls Service Jaipur {9521753030 } ❤️VVIP BHAWNA Call Girl in Jaipur Raj...

khalifaescort01

Independent Call Girls In Jaipur { 8445551418 } ✔ ANIKA MEHTA ✔ Get High Profile Most Luxurious Call Girl With Real Photos Booking Details Are here 05-May-2024( Mj) Click On WhatsApp Chat +91-8445551418 Jaipur Escorts Make You Feel Like Royalty Jaipur Escorts catering to high profile clients are available 24-7 to meet their clients' needs and are also available for dinner dates, business conferences, foreign travel trips and clubbing activities. Their customers are contacted directly through in order to prevent risky situations from developing.is home to some of India's most beautiful women. These girls come highly educated with great backgrounds; furthermore they are extremely beautiful and will make you feel like royalty if hired for hours or days! Siya Khan | FOR BOOKING CALL Our All Services :- 1 )★ (Oral to consummation) bjnonCovered 2 )★ Special Massage 3 )★ O-Level (Oral sex) 4 )★ Blow Job; 5 )★ COB (Come On Body) 6 )★. Extraball (Have sex ordinarily) 7 )★ A-Level (5 star escort) 8 )★ Strip-bother 9 )★ BBBJ (Bareback Blowjob) 10 )★ Spending time in my rooms 11 )★ BJ (Blowjob Without a Condom) 12 )★ COF (Come On Face) 13 )★ Completion

Independent Call Girls In Jaipur { 8445551418 } ✔ ANIKA MEHTA ✔ Get High Prof...

parulsinha

☑️░ 9630942363 ░ CALL GIRLS ░ VIP ░ ESCORT ░ SERVICES ░ AGENCY ░ 9630942363 THE GENUINE ESCORT AGENCY VIP LUXURY CALL GIRLS HIGH CLASS MODELS CALL GIRLS GENUINE ESCORT BOOK BOOK APPOINTMENT - 9630942363 THE GENUINE ESCORT AGENCY BEST VIP CALL GIRLS & ESCORTS SERVICE 9630942363 VIP CALL GIRLS ALL TYPE WOMEN AVAILABLE INCALL & OUTCALL BOTH AVAILABLE BOOK NOW 9630942363 VIP GENUINE INDEPENDENT ESCORT AGENCY VIP PRIVATE AUNTIES BEAUTIFUL LOOKING HOT AND SEXT GIRLS AND PARTY TYPE GIRLS YOU WANT SERVICE THEN CALL THIS NUMBER 9630942363 ROOM ALSO PROVIDE HOME & HOTELS SERVICE FULL SAFE AND SECURE WORK WITHOUT CONDOMS, ORAL, SUCKING, LIP TO LIP, ANAL, BACK SHOTS, SEX 69, WITHOUT BLOWJOB AND MUCH MORE FOR BOOKING 9630942363

Call Girls Vasai Virar Just Call 9630942363 Top Class Call Girl Service Avail...

GENUINE ESCORT AGENCY

9630942363 Genuine Call Girls In Ahmedabad Gujarat Call Girls Service

GENUINE ESCORT AGENCY

Brown: Is the Peer Review Journal Dead?

1. Is the Peer Review Journal Dead? Professor Tony Brown Senior Staff Specialist Department of Emergency Medicine Royal Brisbane and Women’s Hospital

2. Competing Interests Declaration Professor Tony Brown Educational / research funding: Astra Zeneca, Boehringer Ingelheim, Roche, Sanofi-Aventis, Shire. Avant.

3. 550,000

4. 550,000 > 1 / minute

5. 550,000 > 1 / minute >150 this morning

6. 550,000 > 1 / minute >150 this morning > 5,600 (MedlineTM)

7. Is the Peer Review Journal Dead? Aims • What are journals for ? • What do they do ? • Who benefits ? • What are the problems ? • What are the alternatives ?

8. What are journals for ?

9. What are journals for ? • Registration • Certification • Awareness • Archiving

10. What do they do ?

11. What do they do ? • Online submission • Peer review • Editorial decision • Production • Publication

12. Who benefits ?

13. Who benefits ? • Author • Publisher • Editor / peer reviewers

14. What are the problems?

15. What are the problems? • Peer review • Most papers are rubbish • Research hijacked • Restricted full-text access

16. What are the problems? Peer review “Slow, expensive, ineffective, a lottery, biased, incapable of detecting fraud and prone to abuse” Smith R. BMJ 2004;329:242-4

17. What are the problems? Most papers are rubbish • “Words on paper rarely lead directly to change – and thank goodness they don’t, considering the rubbish that journals often publish”. Smith R. BMJ 2004;329:242-4 • Few trials are valid and relevant ( <1% – 7% ) Haynes RB. ACP J Club 1993;119:A22-A23 Scott I, Glaziou P. Med J Aust 2012;197:374-8

18. What are the problems? Research hijacked Radcliffe Publishing 2013 Harper Collins 2013

19. What are the problems? Restricted full-text access $24 billion biomedical publishing industry

20. What are the alternatives?

21. What are the alternatives? • Release ALL data / publish negative trials • Focus on the reader • Post publication review • ‘publish then filter’ • rating systems / Web 2.0 tools / crowdsourcing • Educational / translational focus …

22. What are the alternatives? Educational / translational focus Websites Blog posts Case studies Teaching videos Podcasts Elearning modules Apps ALL informed by the best literature

23. Is the Peer Review Journal Dead? Conclusions • Not yet – but smelling badly ! • Return the focus back onto the reader • Expect and embrace all forms of post publication review • Focus on education / translation

24. Is the Peer Review Journal Dead? Conclusions • Not yet – but smelling badly … • Return the focus back onto the reader • Expect / embrace post publication review • Focus on education / translation • EXCEPTION ! Emerg Med Australas 2014; 26 (1). Feb issue

Brown: Is the Peer Review Journal Dead?

Recomendados

Recomendados

Mais conteúdo relacionado

Semelhante a Brown: Is the Peer Review Journal Dead?

Semelhante a Brown: Is the Peer Review Journal Dead? (20)

Mais de SMACC Conference

Mais de SMACC Conference (20)

Último

Último (20)

Brown: Is the Peer Review Journal Dead?