Presented March 18, 2010 by Dr. Barry K. Logan, PhD, DABFT, NMS Labs National Director of Forensic Services This presentation reviews the rising popularity and spread of Salvia divinorum, from its origins in religious ceremonies to its current status as a potent recreational hallucinogenic drug. The intense dissociative effects of the drug are described, the consequences of long term use, and its forensic significance considered. The presentation also assesses the efforts by various jurisdictions to schedule and outlaw the drug, and presents approaches to chemical and toxicological analysis of its active ingredients and metabolites, Salvinorins A and B.