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What Is Cholesterol?
            •   We may associate cholesterol
                with fatty foods, but most of the
                waxy substance is made by our
                own bodies. The liver produces
                75% of the cholesterol that
                circulates in our blood. The other
                25% comes from food. At normal
                levels, cholesterol actually plays
                an important role in helping cells
                do their jobs. But cholesterol
                levels are precariously high in
                more than 100 million Indians.
Symptoms of High Cholesterol

                •   High cholesterol does not cause
                    any symptoms. But it does cause
                    damage deep within the body.
                    Over time, too much cholesterol
                    may lead to a buildup of plaque
                    inside the arteries. Known as
                    atherosclerosis, this condition
                    narrows the space available for
                    blood flow and can trigger heart
                    disease. The good news is high
                    cholesterol is simple to detect,
                    and there are many ways to bring
                    it down.
Cholesterol Testing

            • People older than 20 should have
              their cholesterol levels checked
              at least once every five years.
              This is done with a simple blood
              test known as a fasting
              lipoprotein profile. It measures
              the different forms of cholesterol
              that are circulating in your blood
              after you avoid eating for 9 to 12
              hours. The results show your
              levels of "bad" cholesterol,
              "good" cholesterol, and
              triglycerides.
"Bad" Cholesterol
           •   Most of the cholesterol in the
               blood is carried by proteins called
               low density lipoproteins or LDL.
               This is known as the bad
               cholesterol because it combines
               with other substances to clog the
               arteries. A diet high in saturated
               fats and trans fats tends to raise
               the level of LDL cholesterol. For
               most people, an LDL score below
               100 is healthy, but people with
               heart disease may need to aim
               even lower.
"Good" Cholesterol
            •   Up to a third of blood cholesterol
                is carried by high-density
                lipoproteins or HDL. This is called
                good cholesterol because it helps
                remove bad cholesterol,
                preventing it from building up
                inside the arteries. The higher the
                level of HDL cholesterol, the
                better. People with too little are
                more likely to develop heart
                disease. Eating healthy fats, such
                as olive oil, may help boost HDL
                cholesterol.
Triglycerides
          •   The body converts excess
              calories, sugar, and alcohol into
              triglycerides, a type of fat that is
              carried in the blood and stored in
              fat cells throughout the body.
              People who are overweight,
              inactive, smokers, or heavy
              drinkers tend to have high
              triglycerides, as do those who eat
              a very high-carb diet. A
              triglycerides score of 150 or
              higher puts you at risk for
              metabolic syndrome, which is
              linked to heart disease and
              diabetes.
Total Cholesterol
           •   Total cholesterol measures the
               combination of LDL, HDL, and
               VLDL (very low density
               lipoprotein) in your bloodstream.
               VLDL is a precursor of LDL, the
               bad cholesterol. A total
               cholesterol score of under 200 is
               considered healthy in most cases.
               People who score in the "high"
               range have an increased risk of
               developing heart disease
               compared to those who score
               below 200.
Cholesterol Ratio
          •   To calculate your cholesterol
              ratio, divide your total
              cholesterol by your HDL
              cholesterol. For example, a total
              score of 200 divided by an HDL
              score of 50 equals a cholesterol
              ratio of 4 to 1. Doctors
              recommend maintaining a ratio
              of 4 to 1 or lower. The smaller the
              ratio, the better. While this figure
              is useful in estimating heart
              disease risk, it's not as important
              in guiding treatment. Doctors
              look at total cholesterol, HDL
              cholesterol, and LDL cholesterol
              to determine treatment.
Cholesterol in Food
            •   Cholesterol-rich foods, like eggs,
                shrimp, and lobster are no longer
                completely forbidden. Research
                shows that the cholesterol we eat
                has only a small effect on blood
                cholesterol levels for most
                people. A few people are
                "responders," whose blood levels
                spike up after eating eggs. But
                for most, saturated fat and trans
                fats are bigger concerns. Daily
                cholesterol limits are 300 mg for
                healthy people and 200 mg for
                those at higher risk. One egg has
                186 mg of cholesterol.
Cholesterol and Family History
                 •   Cholesterol comes from two
                     sources -- the body and food --
                     and either one can contribute to
                     high cholesterol. Some people
                     inherit genes that trigger too
                     much cholesterol production. For
                     others, diet is the main culprit.
                     Saturated fat and cholesterol
                     occur in animal-based foods,
                     including meat, eggs, and dairy
                     products made with milk. In
                     many cases, high cholesterol
                     stems from a combination of diet
                     and genetics.
What Boosts Your Risk?
                 Several factors can make
                 you more likely to develop
                 high cholesterol:
             •   A diet high in saturated fats
                 and cholesterol
             •   A family history of high
                 cholesterol
             •   Being overweight or obese
             •   Getting older
Cholesterol and Gender
             •   Until menopause, women
                 typically have lower total
                 cholesterol levels than men of
                 the same age. They also have
                 higher levels of HDL cholesterol,
                 the good kind. One reason is
                 estrogen: The female sex
                 hormone raises the level of HDL
                 cholesterol. Estrogen production
                 peaks during the childbearing
                 years and drops off during
                 menopause. After age 55, a
                 woman's risk of developing high
                 cholesterol begins to climb.
Cholesterol and Children
               • There's evidence that
                 cholesterol can begin
                 clogging the arteries during
                 childhood, leading to
                 atherosclerosis and heart
                 disease later in life. The
                 American Heart Association
                 recommends kids and
                 teenagers with high
                 cholesterol take steps to
                 bring it down. Ideally, total
                 cholesterol should be below
                 170 in people ages 2 to 19.
Why High Cholesterol Matters

                 • High cholesterol is one of the
                   major risk factors for coronary
                   artery disease, heart attacks, and
                   strokes. It also appears to boost
                   the risk of Alzheimer's disease. As
                   we saw earlier, high cholesterol
                   leads to a buildup of plaque that
                   narrows the arteries. This is
                   dangerous because it can restrict
                   blood flow. If the blood supply to
                   a part of the heart or brain is
                   completely cut off, the result is a
                   heart attack or stroke.
Cholesterol Buster: Eat More Fiber
                    • Diet changes offer a
                      powerful way to fight high
                      cholesterol. If you've ever
                      wondered why some
                      cereals claim to be heart-
                      healthy, it's the fiber. The
                      soluble fiber found in many
                      foods helps reduce LDL, the
                      bad cholesterol. Good
                      sources of soluble fiber
                      include whole-grain breads
                      and cereals, oatmeal, fruits,
                      dried fruits, vegetables, and
                      legumes such as kidney
                      beans.
Cholesterol Buster: Know Your Fats
                    •   No more than 35% of your daily
                        calories should come from fat. But
                        not all fats are equal. Saturated fats
                        -- from animal products and
                        tropical oils -- raise LDL cholesterol.
                        Trans fats carry a double-whammy,
                        boosting bad cholesterol, while
                        lowering the good kind. These two
                        bad fats are found in many baked
                        goods, fried foods (doughnuts,
                        french fries, chips), stick margarine,
                        and cookies. Unsaturated fats may
                        lower LDL when combined with
                        other healthy diet changes. They're
                        found in avocados, olive oil, and
                        peanut oil.
Cholesterol Buster: Smart Protein
                   •   Meat and full-fat milk offer
                       plenty of protein, but they are
                       also major sources of cholesterol.
                       You may be able to reduce LDL
                       cholesterol by switching to soy
                       protein, such as tofu, at some
                       meals. Fish is another great
                       choice. It's rich in omega-3 fatty
                       acids, which can improve
                       cholesterol levels. The American
                       Heart Association recommends
                       eating fish at least twice a week.
Cholesterol Buster: Low-Carb Diet
                   • There's growing evidence
                     that low-carb diets may be
                     better than low-fat diets for
                     improving cholesterol
                     levels. In a two-year study
                     funded by the National
                     Institutes of Health, people
                     who followed a low-carb
                     plan had significantly better
                     HDL (good cholesterol)
                     levels than those who
                     followed a low-fat plan.
Cholesterol Buster: Lose Weight

                 • If you're overweight, talk to
                   your doctor about
                   beginning a weight loss
                   program. Losing weight can
                   help you reduce your levels
                   of triglycerides, LDL, and
                   total cholesterol. Shedding
                   even a few pounds can also
                   boost your good cholesterol
                   level -- it tends to go up 1
                   point for every 6 pounds
                   you lose.
Cholesterol Buster: Quit Smoking
                  • Giving up tobacco is tough,
                    but here's one more reason
                    to try. When you stop
                    smoking, your good
                    cholesterol is likely to
                    improve by as much as 10%.
                    You may be more successful
                    if you combine several
                    smoking cessation
                    strategies. Talk to your
                    doctor about which options
                    are best for you.
Cholesterol Buster: Exercise
               •   If you're healthy but not very
                   active, starting an aerobic
                   exercise program could increase
                   your good cholesterol by 5% in
                   the first two months. Regular
                   exercise also lowers bad
                   cholesterol. Choose an activity
                   that boosts your heart rate, such
                   as running, swimming, or walking
                   briskly, and aim for at least 30
                   minutes on most days of the
                   week. It doesn't have to be 30
                   continuous minutes; two 15-
                   minute walks works just as well.
Treatment: Medications
             •   If high cholesterol runs in your
                 family, diet and exercise may not
                 be enough to get your numbers
                 where you want them. In that
                 case, medication can give your
                 cholesterol levels an extra nudge.
                 Statins are usually the first
                 choice. They block the production
                 of cholesterol in the liver. Other
                 options include cholesterol
                 absorption inhibitors, bile acid
                 resins, and fibrates. Your doctor
                 may recommend a combination
                 of these medications.
Treatment: Supplements
             •   Certain dietary supplements may
                 also improve cholesterol levels.
                 These include flaxseed oil, fish oil,
                 and plant sterols, such as beta-
                 sitosterol. Prescription niacin, a
                 b-complex vitamin, has been
                 found to raise good cholesterol
                 while reducing bad cholesterol.
                 Niacin found in ordinary
                 supplements should not be used
                 to lower cholesterol.
Herbal Remedies
              Some studies suggest garlic
              can knock a few percentage
              points off total cholesterol.
              But garlic pills can have side
              effects and may interact
              with medications. Other
              herbs that may reduce
              cholesterol include:
          •   Fenugreek seeds
          •   Artichoke leaf extract
          •   Yarrow
          •   Holy basil
How Low Should You Go?
            •   Many people are able to lower
                cholesterol levels through a
                combination of medication and
                lifestyle changes. But how low is
                low enough? For people with
                diabetes or a high risk of
                developing heart disease, an LDL
                score of less than 100 is
                desirable. If you already have
                heart disease or coronary artery
                disease, some doctors
                recommend reducing LDL to 70
                or lower.
Can the Damage Be Undone?
               •   It takes years for high cholesterol
                   to clog the arteries with plaque.
                   But there is evidence that
                   atherosclerosis can be reversed,
                   at least to some degree. Dean
                   Ornish, MD, has published several
                   studies showing that a low-fat
                   vegetarian diet, stress
                   management, and moderate
                   exercise can chip away at the
                   build-up inside the coronary
                   arteries. Other research supports
                   the idea that big drops in
                   cholesterol can somewhat help
                   open clogged arteries.
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Cholesterol

  • 1. What Is Cholesterol? • We may associate cholesterol with fatty foods, but most of the waxy substance is made by our own bodies. The liver produces 75% of the cholesterol that circulates in our blood. The other 25% comes from food. At normal levels, cholesterol actually plays an important role in helping cells do their jobs. But cholesterol levels are precariously high in more than 100 million Indians.
  • 2. Symptoms of High Cholesterol • High cholesterol does not cause any symptoms. But it does cause damage deep within the body. Over time, too much cholesterol may lead to a buildup of plaque inside the arteries. Known as atherosclerosis, this condition narrows the space available for blood flow and can trigger heart disease. The good news is high cholesterol is simple to detect, and there are many ways to bring it down.
  • 3. Cholesterol Testing • People older than 20 should have their cholesterol levels checked at least once every five years. This is done with a simple blood test known as a fasting lipoprotein profile. It measures the different forms of cholesterol that are circulating in your blood after you avoid eating for 9 to 12 hours. The results show your levels of "bad" cholesterol, "good" cholesterol, and triglycerides.
  • 4. "Bad" Cholesterol • Most of the cholesterol in the blood is carried by proteins called low density lipoproteins or LDL. This is known as the bad cholesterol because it combines with other substances to clog the arteries. A diet high in saturated fats and trans fats tends to raise the level of LDL cholesterol. For most people, an LDL score below 100 is healthy, but people with heart disease may need to aim even lower.
  • 5. "Good" Cholesterol • Up to a third of blood cholesterol is carried by high-density lipoproteins or HDL. This is called good cholesterol because it helps remove bad cholesterol, preventing it from building up inside the arteries. The higher the level of HDL cholesterol, the better. People with too little are more likely to develop heart disease. Eating healthy fats, such as olive oil, may help boost HDL cholesterol.
  • 6. Triglycerides • The body converts excess calories, sugar, and alcohol into triglycerides, a type of fat that is carried in the blood and stored in fat cells throughout the body. People who are overweight, inactive, smokers, or heavy drinkers tend to have high triglycerides, as do those who eat a very high-carb diet. A triglycerides score of 150 or higher puts you at risk for metabolic syndrome, which is linked to heart disease and diabetes.
  • 7. Total Cholesterol • Total cholesterol measures the combination of LDL, HDL, and VLDL (very low density lipoprotein) in your bloodstream. VLDL is a precursor of LDL, the bad cholesterol. A total cholesterol score of under 200 is considered healthy in most cases. People who score in the "high" range have an increased risk of developing heart disease compared to those who score below 200.
  • 8. Cholesterol Ratio • To calculate your cholesterol ratio, divide your total cholesterol by your HDL cholesterol. For example, a total score of 200 divided by an HDL score of 50 equals a cholesterol ratio of 4 to 1. Doctors recommend maintaining a ratio of 4 to 1 or lower. The smaller the ratio, the better. While this figure is useful in estimating heart disease risk, it's not as important in guiding treatment. Doctors look at total cholesterol, HDL cholesterol, and LDL cholesterol to determine treatment.
  • 9. Cholesterol in Food • Cholesterol-rich foods, like eggs, shrimp, and lobster are no longer completely forbidden. Research shows that the cholesterol we eat has only a small effect on blood cholesterol levels for most people. A few people are "responders," whose blood levels spike up after eating eggs. But for most, saturated fat and trans fats are bigger concerns. Daily cholesterol limits are 300 mg for healthy people and 200 mg for those at higher risk. One egg has 186 mg of cholesterol.
  • 10. Cholesterol and Family History • Cholesterol comes from two sources -- the body and food -- and either one can contribute to high cholesterol. Some people inherit genes that trigger too much cholesterol production. For others, diet is the main culprit. Saturated fat and cholesterol occur in animal-based foods, including meat, eggs, and dairy products made with milk. In many cases, high cholesterol stems from a combination of diet and genetics.
  • 11. What Boosts Your Risk? Several factors can make you more likely to develop high cholesterol: • A diet high in saturated fats and cholesterol • A family history of high cholesterol • Being overweight or obese • Getting older
  • 12. Cholesterol and Gender • Until menopause, women typically have lower total cholesterol levels than men of the same age. They also have higher levels of HDL cholesterol, the good kind. One reason is estrogen: The female sex hormone raises the level of HDL cholesterol. Estrogen production peaks during the childbearing years and drops off during menopause. After age 55, a woman's risk of developing high cholesterol begins to climb.
  • 13. Cholesterol and Children • There's evidence that cholesterol can begin clogging the arteries during childhood, leading to atherosclerosis and heart disease later in life. The American Heart Association recommends kids and teenagers with high cholesterol take steps to bring it down. Ideally, total cholesterol should be below 170 in people ages 2 to 19.
  • 14. Why High Cholesterol Matters • High cholesterol is one of the major risk factors for coronary artery disease, heart attacks, and strokes. It also appears to boost the risk of Alzheimer's disease. As we saw earlier, high cholesterol leads to a buildup of plaque that narrows the arteries. This is dangerous because it can restrict blood flow. If the blood supply to a part of the heart or brain is completely cut off, the result is a heart attack or stroke.
  • 15. Cholesterol Buster: Eat More Fiber • Diet changes offer a powerful way to fight high cholesterol. If you've ever wondered why some cereals claim to be heart- healthy, it's the fiber. The soluble fiber found in many foods helps reduce LDL, the bad cholesterol. Good sources of soluble fiber include whole-grain breads and cereals, oatmeal, fruits, dried fruits, vegetables, and legumes such as kidney beans.
  • 16. Cholesterol Buster: Know Your Fats • No more than 35% of your daily calories should come from fat. But not all fats are equal. Saturated fats -- from animal products and tropical oils -- raise LDL cholesterol. Trans fats carry a double-whammy, boosting bad cholesterol, while lowering the good kind. These two bad fats are found in many baked goods, fried foods (doughnuts, french fries, chips), stick margarine, and cookies. Unsaturated fats may lower LDL when combined with other healthy diet changes. They're found in avocados, olive oil, and peanut oil.
  • 17. Cholesterol Buster: Smart Protein • Meat and full-fat milk offer plenty of protein, but they are also major sources of cholesterol. You may be able to reduce LDL cholesterol by switching to soy protein, such as tofu, at some meals. Fish is another great choice. It's rich in omega-3 fatty acids, which can improve cholesterol levels. The American Heart Association recommends eating fish at least twice a week.
  • 18. Cholesterol Buster: Low-Carb Diet • There's growing evidence that low-carb diets may be better than low-fat diets for improving cholesterol levels. In a two-year study funded by the National Institutes of Health, people who followed a low-carb plan had significantly better HDL (good cholesterol) levels than those who followed a low-fat plan.
  • 19. Cholesterol Buster: Lose Weight • If you're overweight, talk to your doctor about beginning a weight loss program. Losing weight can help you reduce your levels of triglycerides, LDL, and total cholesterol. Shedding even a few pounds can also boost your good cholesterol level -- it tends to go up 1 point for every 6 pounds you lose.
  • 20. Cholesterol Buster: Quit Smoking • Giving up tobacco is tough, but here's one more reason to try. When you stop smoking, your good cholesterol is likely to improve by as much as 10%. You may be more successful if you combine several smoking cessation strategies. Talk to your doctor about which options are best for you.
  • 21. Cholesterol Buster: Exercise • If you're healthy but not very active, starting an aerobic exercise program could increase your good cholesterol by 5% in the first two months. Regular exercise also lowers bad cholesterol. Choose an activity that boosts your heart rate, such as running, swimming, or walking briskly, and aim for at least 30 minutes on most days of the week. It doesn't have to be 30 continuous minutes; two 15- minute walks works just as well.
  • 22. Treatment: Medications • If high cholesterol runs in your family, diet and exercise may not be enough to get your numbers where you want them. In that case, medication can give your cholesterol levels an extra nudge. Statins are usually the first choice. They block the production of cholesterol in the liver. Other options include cholesterol absorption inhibitors, bile acid resins, and fibrates. Your doctor may recommend a combination of these medications.
  • 23. Treatment: Supplements • Certain dietary supplements may also improve cholesterol levels. These include flaxseed oil, fish oil, and plant sterols, such as beta- sitosterol. Prescription niacin, a b-complex vitamin, has been found to raise good cholesterol while reducing bad cholesterol. Niacin found in ordinary supplements should not be used to lower cholesterol.
  • 24. Herbal Remedies Some studies suggest garlic can knock a few percentage points off total cholesterol. But garlic pills can have side effects and may interact with medications. Other herbs that may reduce cholesterol include: • Fenugreek seeds • Artichoke leaf extract • Yarrow • Holy basil
  • 25. How Low Should You Go? • Many people are able to lower cholesterol levels through a combination of medication and lifestyle changes. But how low is low enough? For people with diabetes or a high risk of developing heart disease, an LDL score of less than 100 is desirable. If you already have heart disease or coronary artery disease, some doctors recommend reducing LDL to 70 or lower.
  • 26. Can the Damage Be Undone? • It takes years for high cholesterol to clog the arteries with plaque. But there is evidence that atherosclerosis can be reversed, at least to some degree. Dean Ornish, MD, has published several studies showing that a low-fat vegetarian diet, stress management, and moderate exercise can chip away at the build-up inside the coronary arteries. Other research supports the idea that big drops in cholesterol can somewhat help open clogged arteries.
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