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NUTRITION-DRUG
 INTERACTION
“A drug is taken to prevent or treat sickness
                and disease”
Absorption


Distribution


Metabolism


 Excretion
How Nutrient-Drug Interaction takes
             place?
Food
                     Used by the body                 Energy
(nutrients)




       the body is unable to use a nutrient due to a drug that
       has been taken




                              Nutrient drug interaction
Adverse Effects of Nutrient-Drug
                  Interactions


Some drugs may affect the absorption of nutrients


Some foods, for example, those containing caffeine,
can amplify or modify the effects of certain drugs
DRUG

 INDICATION

POSSIBLE EFFECTS
COUMADIN



Anticoagulant (blood thinner)
POSSIBLE EFFECTS
Vitamin K is a nutrient in
the body that helps blood to
clot


       Vitamin K is present in foods
       such as green, leafy vegetables
       and fish.


  It will interfere with a blood thinner
DILANTIN


Anticonvulsant (anti-seizure)
POSSIBLE EFFECTS
Vitamin D and folic acid levels in the body
are decreased by taking these types of
drugs
NORVASC

Antihypertensive (for high blood
pressure)
POSSIBLE EFFECTS
Consuming foods high in sodium (i.e.,
processed meats, canned foods) will
decrease the effectiveness of the drug
ASPIRIN


Anti-inflammatory/pain reliever
POSSIBLE EFFECTS


Taking large amounts of these drugs will
cause a loss of Vitamin C in the body.
TETRACYCLINE


Antibiotic
POSSIBLE EFFECTS

• Calcium may interact with          the
  effectiveness of the antibiotic.

• Avoid dairy products for two to three
  hours before and after taking the
  medicine.
LIPITOR/ZOCOR

Statins (cholesterol-lowering drugs)
POSSIBLE EFFECTS

Antioxidants (Vitamin A, C, E, B, folic acid)
may interact with the drug by reversing its
effect.
LASIX


Diuretic (water-eliminating)
POSSIBLE EFFECTS


The Drug may decrease appetite thus
    decreasing nutrient intake.
Impact of Food on Effectiveness of a
                 Drug


Nutrients in food may either delay absorption
into the body or speed up elimination from the
body, either or which can impact a drug's
effectiveness
The acidic ingredients in fruit juices are capable
of decreasing the power of antibiotics such as
penicillin
Many medications that are taken to
fight depression can be dangerous if mixed with
beverages
Impact of Drug on Nutritional
                  Status


  Drugs may cause a increase or decrease in
  appetite, leading to a increase or decrease in
  nutrient intake

  Nutritional status may also be impacted by a
  drug's effect on the three main nutrients


Carbohydrates        Fat           Protein
A drug may speed up or slow down the breakdown of
these three nutrients, which are essential to the body's
functioning




When a drug affects the absorption of nutrients from food
into the body, less energy is available to be used by the
body
TIPS FOR AVOIDING INTERACTIONS


 Be sure to read the label on a prescription medicine
 and ask a pharmacist or physician if something is not
 clear.

 Always take medications with a full glass of water

 Read all directions, warnings, and any possible side
 effects printed on all drug labels and information in
 the package
A drug may not work correctly if a medicine is taken
improperly; do not stir medication into food or take
apart capsules (unless told to do so).

Take vitamin and mineral supplements before or after
medicine, as they may interact with certain drugs.

Do not drink alcohol when taking any medicine.

Avoid stirring drugs into hot drinks such as coffee
because the drug's effectiveness can be destroyed by
the hot temperature.

                                                 Contd..
Pharma

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