2. ED Approach to theED Approach to the
Overdose PatientOverdose Patient
3. HistoryHistory
Often unreliableOften unreliable
Rely on EMS, bystanders, family members andRely on EMS, bystanders, family members and
other physiciansother physicians
Psychiatric files: 13B? 5-4762 at GMHPsychiatric files: 13B? 5-4762 at GMH
Where are the bottles?Where are the bottles?
What was the environmental setting (Factory,What was the environmental setting (Factory,
Gas space heater in winter –Gas space heater in winter – think CO!!)think CO!!)
Check pockets, bags, belongingsCheck pockets, bags, belongings
4. Physical exam: Vital signsPhysical exam: Vital signs
Vital signs are very important:Vital signs are very important:
Hyperthermia (ASA, cocaine, anticholinergics)Hyperthermia (ASA, cocaine, anticholinergics)
Hypothermia (opiates, barbiturates and sedatives)Hypothermia (opiates, barbiturates and sedatives)
HTN (cocaine, amphetamines, sympathomimetics)HTN (cocaine, amphetamines, sympathomimetics)
Hypotension (calcium channel and beta blockers)Hypotension (calcium channel and beta blockers)
TachycardiaTachycardia
bradycardia (Clonidine, Organophosphates)bradycardia (Clonidine, Organophosphates)
HypoxemiaHypoxemia
Blood glucose (hypoglycemia from sulfonylureas,Blood glucose (hypoglycemia from sulfonylureas,
insulin overdose)insulin overdose)
5. Physical exam-Neuro examPhysical exam-Neuro exam
Level of consciousness: Glucose!Level of consciousness: Glucose!
Glucose!Glucose!
Do not miss a focal finding.Do not miss a focal finding.
Miosis (clonidine, barbiturates, opiates,Miosis (clonidine, barbiturates, opiates,
cholinergics, pontine stroke)cholinergics, pontine stroke)
6. Physical exam-Neuro examPhysical exam-Neuro exam
Mydriasis (sympathomimetics)Mydriasis (sympathomimetics)
Clonus and rigidityClonus and rigidity
NeurolepticsNeuroleptics
Serotonin receptor agonistsSerotonin receptor agonists
Depolarizing neuromuscular blockersDepolarizing neuromuscular blockers
SeizuresSeizures
Treat with benzodiazepines or barbituratesTreat with benzodiazepines or barbiturates
not phenytoinnot phenytoin
7. Physical exam: Skin examPhysical exam: Skin exam
Dry: anticholinergicDry: anticholinergic
Diaphoretic:Diaphoretic:
cholinergic,cholinergic,
hypoglycemiahypoglycemia
or sympathomimeticor sympathomimetic
Cyanosis: MetHbCyanosis: MetHb
Blisters: Barbs and COBlisters: Barbs and CO
Cherry red: CyanideCherry red: Cyanide
Track marks for IVDATrack marks for IVDA
History Often unreliable
Rely on EMS, bystanders, family members and other physicians
Where are the bottles?
Psychiatric files
The environmental setting Check pockets, bags, belongings
Environmental factors e.g. (Factory, Gas space heater in winter – think CO!!)
Vital signs are very important:
Hyperthermia (ASA, cocaine, anticholinergics)
Hypothermia (opiates, barbiturates and sedatives)
HTN (cocaine, amphetamines, sympathomimetics)
Hypotension (calcium channel and beta blockers)
Tachycardia
bradycardia (Clonidine, Organophosphates)
Hypoxemia
Blood glucose (hypoglycemia from sulfonylureas, insulin overdose)