Puo

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mohammed sediq

Health & Medicine

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What's hot

PUO

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Pyrexia of unknown origin

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The syndrome of pyrexia of unknown origin (PUO) was first defined in 1961 but remains a clinical challenge for many physicians. Different subgroups with PUO have been suggested, each requiring different investigative strategies: classical, nosocomial, neutropenic, and HIV-related. This could be expanded to include the elderly as a fifth group. The causes are broadly divided into four groups: infective, inflammatory, neoplastic, and miscellaneous. Increasing early use of positron emission tomography–computed tomography (PET-CT) and the development of new molecular and serological tests for infection have improved diagnostic capability, but up to 50% of patients still have no cause found despite adequate investigations. Reassuringly, the cohort of undiagnosed patients has a good prognosis. In this article we review the possible aetiologies of The definition of pyrexia of unknown origin (PUO) dates back to 1961; it was described as a persistent fever above 38.3°C (100°F) that evades diagnosis for at least 3 weeks, including 1 week of investigation in hospital. PUO and present a systematic clinical approach to the investigation and management of patients, recommending potential second-line investigations when the etiology is unclear

FEVER OF UNKNOWN ORIGIN (PUO)- APPROACH

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Pyrexia of unknown origin

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PUO

Pyrexia of unknown origin

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PUO

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Puo at aizawl hosp

Fever of unknown origin

fever of unknown origin

Fever unknown Origin

FEVER OF UNKNOWN ORIGIN (PUO)- APPROACH

Pyrexia of unknown origin

Fever Of Unknown Origin

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Adult-onset Still's disease is a form of rheumatoid arthritis that was characterized by Bywaters in 1971. Its main feature is a combination of symptoms such as high fever, cutaneous rash during fever peaks, joint and muscle pain, lymph node enlargement, increased white cell count especially polymorphonuclear neutrophils and abnormalities of liver metabolism. None of these symptoms is sufficient to establish the diagnosis and infact may be present in several other diseases such as neoplastic and infectious diseases. Thus AOSD is a “diagnosis of exclusion”.

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