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2.04 Understand the
functions and disorders of the
      lymphatic system
2.04 Understand the
            functions and disorders
            of the lymphatic system
   What are the functions of the lymphatic system?
   What is the importance of the lymphatic system as
    it relates to immunity?
   How do you relate the body’s use of nutrients to
    the lymphatic system?
   What are some disorders of the lymphatic system
    and how are they treated?

                   2.04 Understand the functions and
                                                        2
                   disorders of the lymphatic system
The Functions of the
            Lymphatic System

   Fluid balance
   Lymphocyte production
   Filtration
   Immunity




                   2.04 Understand the functions and
                                                       3
                   disorders of the lymphatic system
The Lymphatic System

Fluid Balance


                                       ____     ____
                                       Fluid    Fluid
                                        IN      OUT




            2.04 Understand the functions and
                                                        4
            disorders of the lymphatic system
The Lymphatic System

Lymphocyte production




           2.04 Understand the functions and
                                               5
           disorders of the lymphatic system
The Lymphatic System



Filtration


    2.04 Understand the functions and
                                        6
    disorders of the lymphatic system
The Lymphatic System

                                          Immunity Notes
                     Immunity
               ___________________
               ___________________
               ___________________


     Natural Immunity
_______________________
                                             Handout
                                 Acquired Immunity
                              _____________________
_______________________       _____________________
_______________________       _____________________
_______________________       _____________________
_______________________       _____________________


                   Passive Acquired Immunity        Active Acquired Immunity
                ____________________________    ____________________________
                ____________________________    ____________________________
                ____________________________    ____________________________
                ____________________________    ____________________________
                           ________              __________________________


                                   Natural Acquired Immunity       Artificial Acquired Immunity
                                ____________________________    ____________________________
                                ____________________________    ____________________________
                                ____________________________    ____________________________
                                ____________________________    ____________________________
                                ____________________________             ______________

                            2.04 Understand the functions and
                                                                                                  7
                            disorders of the lymphatic system
The Lymphatic System

Immunity
What   is immunity?




               2.04 Understand the functions and
                                                   8
               disorders of the lymphatic system
The Lymphatic System

Natural immunity




        2.04 Understand the functions and
                                            9
        disorders of the lymphatic system
The Lymphatic System

Natural immunity

Discuss the body’s natural immune
processes seen in this picture.




                2.04 Understand the functions and
                                                    10
                disorders of the lymphatic system
Acquired Immunity

   Passive
   Active



   2.04 Understand the functions and
                                       11
   disorders of the lymphatic system
The Lymphatic System


Passive Acquired Immunity




           2.04 Understand the functions and
                                               12
           disorders of the lymphatic system
The Lymphatic System

Active Acquired Immunity




          2.04 Understand the functions and
                                              13
          disorders of the lymphatic system
The Lymphatic System

Natural Acquired Immunity




        2.04 Understand the functions and
                                            14
        disorders of the lymphatic system
The Lymphatic System

Artificial Acquired Immunity




       2.04 Understand the functions and
                                           15
       disorders of the lymphatic system
The Lymphatic System
                        REVIEW

What are the functions of the lymphatic system?
1

2

3

4




                 2.04 Understand the functions and
                                                     16
                 disorders of the lymphatic system
Spread of Infection




Standard Precautions
   Hand Washing
     2.04 Understand the functions and
                                         17
     disorders of the lymphatic system
The Lymphatic System

Anaphylactic Shock




       2.04 Understand the functions and
                                           18
       disorders of the lymphatic system
The Lymphatic System

AIDS
 How is it diagnosed?
 What do these terms mean?
    HIV (Human Immunodeficiency Virus)

    AIDS (Acquired

      Immunodeficiency Syndrome)



              2.04 Understand the functions and
                                                  19
              disorders of the lymphatic system
The Lymphatic System

Acquired Immunodeficiency Syndrome
             (AIDS)




          2.04 Understand the functions and
                                              20
          disorders of the lymphatic system
The Lymphatic System


Cancer




         2.04 Understand the functions and
                                             21
         disorders of the lymphatic system
The Lymphatic System

Hodgkin’s Disease / Hodgkin’s Lymphoma




            2.04 Understand the functions and
                                                22
            disorders of the lymphatic system
The Lymphatic System


Infectious Mononucleosis




         2.04 Understand the functions and
                                             23
         disorders of the lymphatic system
The Lymphatic System

Lupus Erythematosus




    2.04 Understand the functions and
                                        24
    disorders of the lymphatic system
The Lymphatic System


       Lymphadenitis
Lymph aden itis




            2.04 Understand the functions and
                                                25
            disorders of the lymphatic system
The Lymphatic System


Lymphedema




                       Photo used with written permission by the Mayo Clinic.



        2.04 Understand the functions and
                                                                                26
        disorders of the lymphatic system
The Lymphatic System

Scleroderma



        2.04 Understand the functions and
                                            27
        disorders of the lymphatic system
The Lymphatic System

Tonsillitis



 http://youtu.be/RTFUpoqhbHo


                 2.04 Understand the functions and
                                                     28
                 disorders of the lymphatic system
2.04 Understand the
            functions and disorders
            of the lymphatic system
   What are the functions of the lymphatic system?
   What is the importance of the lymphatic system as
    it relates to immunity?
   How do you relate the body’s use of nutrients to
    the lymphatic system?
   What are some disorders of the lymphatic system
    and how are they treated?

                   2.04 Understand the functions and
                                                       29
                   disorders of the lymphatic system

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Functions and Disorders of the Lymphatic System

  • 1. 2.04 Understand the functions and disorders of the lymphatic system
  • 2. 2.04 Understand the functions and disorders of the lymphatic system  What are the functions of the lymphatic system?  What is the importance of the lymphatic system as it relates to immunity?  How do you relate the body’s use of nutrients to the lymphatic system?  What are some disorders of the lymphatic system and how are they treated? 2.04 Understand the functions and 2 disorders of the lymphatic system
  • 3. The Functions of the Lymphatic System  Fluid balance  Lymphocyte production  Filtration  Immunity 2.04 Understand the functions and 3 disorders of the lymphatic system
  • 4. The Lymphatic System Fluid Balance ____ ____ Fluid Fluid IN OUT 2.04 Understand the functions and 4 disorders of the lymphatic system
  • 5. The Lymphatic System Lymphocyte production 2.04 Understand the functions and 5 disorders of the lymphatic system
  • 6. The Lymphatic System Filtration 2.04 Understand the functions and 6 disorders of the lymphatic system
  • 7. The Lymphatic System Immunity Notes Immunity ___________________ ___________________ ___________________ Natural Immunity _______________________ Handout Acquired Immunity _____________________ _______________________ _____________________ _______________________ _____________________ _______________________ _____________________ _______________________ _____________________ Passive Acquired Immunity Active Acquired Immunity ____________________________ ____________________________ ____________________________ ____________________________ ____________________________ ____________________________ ____________________________ ____________________________ ________ __________________________ Natural Acquired Immunity Artificial Acquired Immunity ____________________________ ____________________________ ____________________________ ____________________________ ____________________________ ____________________________ ____________________________ ____________________________ ____________________________ ______________ 2.04 Understand the functions and 7 disorders of the lymphatic system
  • 8. The Lymphatic System Immunity What is immunity? 2.04 Understand the functions and 8 disorders of the lymphatic system
  • 9. The Lymphatic System Natural immunity 2.04 Understand the functions and 9 disorders of the lymphatic system
  • 10. The Lymphatic System Natural immunity Discuss the body’s natural immune processes seen in this picture. 2.04 Understand the functions and 10 disorders of the lymphatic system
  • 11. Acquired Immunity Passive Active 2.04 Understand the functions and 11 disorders of the lymphatic system
  • 12. The Lymphatic System Passive Acquired Immunity 2.04 Understand the functions and 12 disorders of the lymphatic system
  • 13. The Lymphatic System Active Acquired Immunity 2.04 Understand the functions and 13 disorders of the lymphatic system
  • 14. The Lymphatic System Natural Acquired Immunity 2.04 Understand the functions and 14 disorders of the lymphatic system
  • 15. The Lymphatic System Artificial Acquired Immunity 2.04 Understand the functions and 15 disorders of the lymphatic system
  • 16. The Lymphatic System REVIEW What are the functions of the lymphatic system? 1 2 3 4 2.04 Understand the functions and 16 disorders of the lymphatic system
  • 17. Spread of Infection Standard Precautions Hand Washing 2.04 Understand the functions and 17 disorders of the lymphatic system
  • 18. The Lymphatic System Anaphylactic Shock 2.04 Understand the functions and 18 disorders of the lymphatic system
  • 19. The Lymphatic System AIDS How is it diagnosed? What do these terms mean?  HIV (Human Immunodeficiency Virus)  AIDS (Acquired Immunodeficiency Syndrome) 2.04 Understand the functions and 19 disorders of the lymphatic system
  • 20. The Lymphatic System Acquired Immunodeficiency Syndrome (AIDS) 2.04 Understand the functions and 20 disorders of the lymphatic system
  • 21. The Lymphatic System Cancer 2.04 Understand the functions and 21 disorders of the lymphatic system
  • 22. The Lymphatic System Hodgkin’s Disease / Hodgkin’s Lymphoma 2.04 Understand the functions and 22 disorders of the lymphatic system
  • 23. The Lymphatic System Infectious Mononucleosis 2.04 Understand the functions and 23 disorders of the lymphatic system
  • 24. The Lymphatic System Lupus Erythematosus 2.04 Understand the functions and 24 disorders of the lymphatic system
  • 25. The Lymphatic System Lymphadenitis Lymph aden itis 2.04 Understand the functions and 25 disorders of the lymphatic system
  • 26. The Lymphatic System Lymphedema Photo used with written permission by the Mayo Clinic. 2.04 Understand the functions and 26 disorders of the lymphatic system
  • 27. The Lymphatic System Scleroderma 2.04 Understand the functions and 27 disorders of the lymphatic system
  • 28. The Lymphatic System Tonsillitis http://youtu.be/RTFUpoqhbHo 2.04 Understand the functions and 28 disorders of the lymphatic system
  • 29. 2.04 Understand the functions and disorders of the lymphatic system  What are the functions of the lymphatic system?  What is the importance of the lymphatic system as it relates to immunity?  How do you relate the body’s use of nutrients to the lymphatic system?  What are some disorders of the lymphatic system and how are they treated? 2.04 Understand the functions and 29 disorders of the lymphatic system

Editor's Notes

  1. The lymphatic vessels drain excess fluids that accumulates in tissues thus preventing edema. The collected fluid is deposited into the veins and carried throughout the circulatory system.
  2. Lymphocytes are help the body by synthesizing and releasing antibody molecules and by protecting against the formation of cancer cells
  3. Lymph nodes filter out harmful bacteria from the body. When the lymph node cannot filter the bacteria out, it will become enlarged until the lymphocytes can break down the bacteria (phagocytosis)
  4. The body’s ability to resist pathogens and foreign materials and the diseases they cause in the body.
  5. The immunity we have when we are born. It is inherited and is permanent. Parts of our natural immunity is Our unbroken skin Cellular secretions (mucus and tears) Blood phagocytes Local inflammation
  6. Blood proteins (fibrinogen) and platelets go to the area of injury to stop the blood loss. Pus may form to get rid of bacteria in the wound.
  7. Acquired immunity is the reaction that occurs as a result of exposure to invaders.
  8. Passive acquired immunity is “borrowed” immunity. It is acquired artificially by injecting antibodies from the blood of other individuals or animals into a person’s body to protect him or her from a specific disease. It is an immediate response but will only last for 3-5 weeks. This is only used when someone has been exposed to a disease such as measles, tetanus, and infectious hepatitis and has not acquired active immunity to that disease. The borrowed antibodies will provide temporary protection
  9. This immunity lasts longer than passive acquired immunity Two types natural acquired immunity artificial acquired immunity
  10. Results from having a disease and recovering from the disease. Example- someone who has had the chicken pox will not ordinarily get the chicken pox again. The person has manufactured antibodies against the chicken pox.
  11. This immunity is a result of being inoculated with a vaccine, antigen, or toxoid. Example- a children is vaccinated against measles will be given a very mild form of the disease. The child’s body will be stimulated to manufacture its own antibodies.
  12. 1-Fluid balance 2-Lymphocyte production 3-Filtration 4-Immunity
  13. This happens as a result if an antigen-antibody reaction that stimulates a massive secretion of histamine. This can be caused by insect stings or injected medications (penicillin). Experience breathing problems, headache, facial swelling, falling blood pressure, stomach cramps, and vomiting. The treatment is an injection of antihistamine or adrenaline. If treatment is not given, death can occur in minutes.
  14. AIDS is a disease that suppresses the body’s natural immune defense system. AIDS/HIV is diagnosed through testing a person’s blood for the presence of antibodies to HIV. To confirm diagnosis of HIV a Western Blot test is completed.
  15. Acquired- the disease is not inherited Immune- refers to the body’s natural defenses against cancers, disease, and infections Deficiency- lacks cellular immunity Syndrome- involves the set of diseases or conditions that are present to signal the diagnosis Transmitted through sexual contact with an infected partner. Virus enters the body through the lining of the vagina, vulva, penis, rectum, or mouth during sex. Sharing needles- the infected blood is injected into the body In utero or a birth by an infected mother Transmission of HIV through blood transfusions The virus doesn’t survive for long outside the body. You can not spread the virus through coughing, sneezing, hugging, shaking hands, or sharing eating utensils Symptoms Early stages people may experience flulike symptoms including fever, HA, malaise, and enlarged lymph glands. This may be present for a week to a month and then disappear. More symptoms may not appear for another 10 years. Before the person has AIDS, there will be weight loss, lack of energy, frequent fevers and sweats, persistent yeast infections (oral or vaginal), persistent skin rashes, flaky skin, pelvic inflammatory disease that doesn’t respond to treatment and even short term memory loss. Treatment No cure but drugs can be used to help control the virus
  16. Cancer is the 2 nd most common cause of death in the US. Cancerous cells will continue to grow, crowding out the healthy cells, interfering with body functions, and drawing nutrients away from the body’s tissues
  17. Form of cancer in the lymph nodes. In Hodgkin's lymphoma, cells in the lymphatic system grow abnormally and may spread beyond the lymphatic system. As Hodgkin's lymphoma progresses, it compromises your body's ability to fight infection. Tends to affect males more often than females. Symptoms are painless swelling of lymph nodes Treatment is chemotherapy and radiation
  18. Known as the Kissing disease or mono It is caused by the Epstein-Barr virus. Its symptoms are enlarged lymph nodes, fever, and physical and mental fatigue. There will also be an increased number of leukocytes. Mono is treated symptomatically ( tx the symptoms as they appear). Bed rest is essential.
  19. Chronic inflammatory autoimmune disease SLE most commonly experience profound fatigue, rashes, and joint pains. In severe cases, the immune system will attack and damage the brain, kidney, blood, or lungs. Managed with anti-inflammatory medications
  20. Lymph + glands+ inflammation The enlargement of lymph nodes. It often happens when an infection is present and the body is attempting to fight off the infection. The term “swollen glands” is used frequently for this conditon
  21. A condition in which excess fluid collects in body tissues due to loss of flow in the lymphatic vessels Causes abnormal swelling of the affected body parts. Usually affects the arms and legs but it can also develop in the groin. Exercises Wrapping your arm or leg Massage Compression garments Pneumatic compression
  22. Thickening of the skin and blood vessels caused by an autoimmune disease. Complications include loss of movement and difficulty breathing Medicines used to treat scleroderma include: Power anti-inflammatory medicines called corticosteroids Immune-suppressing medications such as methotrexate and Cytoxan Non-steroidal anti-inflammatory drugs (NSAIDs) Other treatments for specific symptoms may include: Medicines for heartburn or swallowing problems Blood pressure medications (particularly ACE inhibitors) for high blood pressure or kidney problems Light therapy to relieve skin thickening Medicines to improve breathing Treatment usually also involves physical therapy.
  23. The tonsils are lymph nodes in the back of the mouth and top of the throat. They normally help to filter out bacteria and other germs to prevent infection in the body. A bacterial or viral infection can cause tonsillitis. Strep throat is a common cause. Difficulty swallowing Ear pain Fever , chills Headache Sore throat - lasts longer than 48 hours and may be severe Tenderness of the jaw and throat Swollen tonsils that are not painful or do not cause other problems do not need to be treated. Your health care provider may not give you antibiotics. You may be asked to come back for a check up later. If tests show you do have strep, your doctor will give you antibiotics. It is important to finish all of your antibiotics as directed by your doctor, even if you feel better. If you do not take them all, the infection can return. The following tips may help your throat feel better: Drink cold liquids or suck on popsicles Drink fluids, especially warm (not hot), bland fluids Gargle with warm salt water Suck on lozenges (containing benzocaine or similar ingredients) to reduce pain (these should not be used in young children because of the choking risk) Take over-the-counter medications, such as acetaminophen (Tylenol) or ibuprofen to reduce pain and fever. Do NOT give a child aspirin. Aspirin has been linked to Reye syndrome. Some people who have repeated infections may need surgery to remove the tonsils (tonsillectomy).