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UNIT 1: INTRODUCTION
     TO BIOLOGY
     TIMBERLANE HIGH SCHOOL
          MEGHIN MARLEY
WHAT IS SCIENCE?

• An organized way of using evidence to learn about
  the natural world.

• The word science can also be used to describe
  what humans already know about the natural
  world.

• It’s important to avoid opinions and biases in
  science so actual facts can be presented.
HOW DO HUMANS EXPLORE SCIENCE?

•   Observe
•   Describe
•   Experiment
•   Read
•   Research
•   Explore

• What are some words or processes that come to
  mind when you think about exploring science?
• Carinbonder.com
OBSERVATION

• Involves observing something with one or more of
  your senses
• Using your senses to gather information
• Which senses do you believe would be most useful
  in gathering scientific information or data?
• Sight
• Sound
• Touch
• Smell
• And sometimes even taste
OBSERVATION

• 1. Quantitative- involves numbers, counting or
  measuring

• 2. Qualitative- observations that cannot be counted
  or measured

• Observations are used in collecting data and the
  formation of evidence
EVIDENCE INTERPRETATION

• What happens after the observations are made?

• How are the observations used to provide an
  understanding of the process you are trying to
  explain?

• Inference: a logical explanation or interpretation
  based on prior knowledge/experience of the
  subject
HOW ARE SCIENTIFIC IDEAS TESTED?

• Once someone has formed a scientific question
  what is the next step?

• The Scientific Method can be used to test a
  hypothesis.
THE BASIC STEPS

• 1. Ask a Question

• 2. Form a Hypothesis

• 3.Design and Conduct an Experiment

• 4. Analyze Results of the Experiment

• 5. Draw Conclusion
THE SCIENTIFIC METHOD

• http://www.youtube.com/watch?v=LMg_asQ3Hto
HYPOTHESIS

• Can answer a scientific question
• Can describe scientific information
• A possible explanation
• Hypotheses can be tested usually through
  controlled experimentation
• Sometimes hypotheses are wrong
• In an If…then format
ALTERNATIVE HYPOTHESES

• H 1, H 2, H 3

• Alternative hypotheses are more likely to be correct

• Multiple alternative hypotheses can be generated
  and tested.
THE SCIENTIFIC METHOD

• Monty Python
• http://www.youtube.com/watch?v=k2MhMsLn9B0
NULL HYPOTHESIS

• H0

• The null hypothesis is a hypothesis which the researcher
  tries to disprove, reject or nullify

• The 'null' often refers to the common view of something,
  while the alternative hypothesis is what the researcher
  really thinks is the cause of a phenomenon.
THE STEPS

•   Do all scientific investigations include all the steps?
•   No
•   Do some investigations include more steps?
•   Yes

• The scientific method is the basis for scientific
  investigation, but it is not set in stone.
• It is a process to help direct scientific inquiry, more
  steps, research, or experimentation can be
  necessary.
• Whywereason.wordpress.com
CR: 3
Why is the scientific method important
for answering scientific questions? Do
your best to describe the process of
the scientific method step by step.
THE PROCESS OF SCIENTIFIC
            INVESTIGATION
• The Process of Scientific Investigation can be done
  in a series of stages, formal research and testing is
  carried out in this manor.
• 1. Observations
• 2. Form Hypotheses
• 3. Predictions
• 4. Experimentation
• 5. Make conclusions
EXPERIMENTAL DESIGN

• Developing and setting up a controlled experiment
  to test your hypothesis

• Controlled Experiment: When only one variable is
  changed at a time
• Manipulated variable: variable that is deliberately
  changed
• Responding variable: variable that is observed and
  changes in response to the manipulated variable
MORE ON VARIABLES

• Independent Variable- researcher can control,
  concentration of a chemical, timing of
  measurements
• (manipulated variable)

• Dependent Variable- response that is measured
• (responding variable)
CONTROLLED EXPERIMENTS

• What does it mean to have a controlled
  experiment?

• When an experiment is run, one variable is altered
  and the all other variables will remain constant.

• A controlled experiment will be run the same way
  but no variables will be altered and all other
  variables will be kept constant.
DRAWING CONCLUSIONS

• Data from experiments is evaluated



• The hypothesis is supported or rejected
THEORIES

• Once you have supported your hypothesis through
  testing does it become a theory?

• What is a theory?

• A theory is a well supported explanation involving a
  broad range of observations for a particular
  phenomenon
  • Multiple investigations have been done and proven the
    hypothesis to be true
THEORIES

• Theories can be widely excepted, but should not be
  considered absolute truth

• New evidence may be uncovered

• New technologies can lead to new discoveries
REDI’S EXPERIMENT

• In ancient times people did not understand many
  biological lifecycles, people accepted the idea
  that some organisms, fruit-flies, maggots, would
  suddenly just appear

• Spontaneous Generation- sudden appearance of
  organisms from non-living matter
REDI’S EXPERIMENT

• In 1668 Francesco Redi observed flies on meat and
  several days later the appearance of maggot, he
  wanted to test his hypothesis that maggots came
  from flies and developed a controlled experiment.

• He used 8 jars, 4 he left open to the air and 4 he
  covered with muslin, a fabric that prevented flies
  from getting to the meat.
REDI’S EXPERIMENT




• Icmrschool.org
REDI’S EXPERIMENT

• What was the control group?

• The jars that were left uncovered
  • This was the way meat was typically kept


• His hypothesis was that flies were causing the production
  of maggots on the meat


• He was able to prove that the flies were causing the
  maggots by covering the jars, preventing the flies from
  laying eggs in the meat.
VARIABLES IN REDI’S EXPERIMENT

• Manipulated Variables:
  • Muslin covering the jars
• Responding Variables:
  • The maggots appearing or not
• Variables that were controlled:
  • Jars, type of meat, location, temperature, time
JOHN NEEDHAM

• Mid-1700’s
• Englishman
• Used a sealed jar of gravy to try and disprove Redi’s
  claim on spontaneous generation
• He took a jar of gravy and sealed it
• He then heated the gravy “killing off all possible
  microorganisms”
• After several days he examined the gravy, found
  microorganisms and claimed they could have only
  came from the gravy, since the jar was sealed.
JOHN NEEDHAM

• Why do you think there were organisms in the
  gravy?
• Do you think Needham’s findings disproved the
  work of Redi?
• Was Needham’s experiment controlled?
SPALLANZANI’S EXPERIEMENT

• Italian Scholar
• An improvement on Needham’s experiment
• He believed that the gravy had not been heated
  enough to kill all the existing microorganisms
• Preformed a similar experiment to Redi’s
SPALLANZANI’S EXPERIMENT

• Spallanzani claimed that the gravy left open grew
  microorganisms that had entered from the air, the sealed flask
  had no living organisms.
• He concluded that non-living gravy could not produce living
  things

•   What was the control group in Spallanzani’s experiment?
•   Gravy flask left unsealed
•   The manipulated variable was the sealing of the flask
•   The responding variable was microorganism growth
•   He sealed the flask and prevented microorganism growth
LOUIS PASTEUR

• Famous problem solver, Microbiologist
• In 1864 Louis Pasteur designed a flask with a curved
  neck so that air could get into the flask, but
  microorganisms could not
• Other works of Pasteur
  • Saved French wine industry when wine was souring
  • Saved the silk industry through discovery of a silkworm
    disease
  • Discovered and worked with infectious diseases
  • Vaccine for Anthrax bacterial infection in 1881
PASTEUR’S FLASK EXPERIMENT
LOUIS PASTEUR’S GERM THEORY
CAN EVERYTHING SCIENTIFIC BE
    TESTED BY EXPERIMENTATION?
• Animal and insect life cycles
  • The Great White Shark is hard to keep in captivity


• Ecological Interactions
  • How do you simulate all the different environmental factors
    in a controlled way?


• Human Ethics
  • Stem cell research
  • Testing on humans and animals
ALTERNATIVES TO CONTROLLED
           EXPERIMENTS
• Field Studies
  • Observation of animals or other living things in their natural
    environment
• Studies involving large amounts of people or subjects
  • More samples gives more reliable data
• Control of as many factors as possible
  • In a medical study for cancer, people with other health issues
    may be eliminated

• It is important to research what is already out there.
  What has been done on the subject?

• Cite your sources!
So how are we going to use
this information about
science and the process of
scientific investigation to
learn about Biology?
SO WHAT IS BIOLOGY?

• Textbook definition: A field of science that seeks to
  understand the living world. The study of life.

• The study of things that are “living”.

• What does it mean to be “alive”?

• What are some characteristics that help people
  determine whether something is living or non?
http://www.flickr.com/photos/grainspa
ce/2292079476/
www.nationalgeographic.com
www.nationalgeographic.com
THE CHARACTERISTICS OF LIFE

•   Made up of units called cells
•   Maintain stable internal conditions: homeostasis
•   Grow and develop
•   Reproduce
•   Based on a universal genetic code
•   Obtain and use materials and energy
•   Respond to their environment
•   When looking at a species as a whole, living things
    can change over time or evolve
THE CELL

• What is a Cell?
• A cell is a collection of living matter surrounded by
  a membrane that separates it from its surrounding
  environment.




• How are cells organized?
microscopy-uk.org.uk faculty.clintoncc.suny.edu fcps.edu
http://www.ncbi.nlm.nih.gov/books/NB
CELLULAR ORGANIZATION

•   All living things are made up of one or more cells
•   Cells can be simple to very complex
•   Cells can grow and reproduce
•   Single-Celled Organisms
    • Algae
    • Bacteria
    • Paramecia, A protist
• There are around 100 trillion cells in the human body
HOMEOSTASIS

• Living things must expend energy to keep their cells
  within certain limits for proper form and function
• Organisms are able to maintain certain internal
  environments even when the environment outside
  of them is constantly changing
• An organism's ability to do this allows them to
  survive
HOMEOSTATIS
GROWTH & DEVELOPMENT

• Every different organism has a specific
  pattern of growth
• A single egg cell once fertilized can divide
  over and over
• Cells differentiate forming tissues and organs
sites.google.com
REPRODUCTION

• The reproduction of new generations
• Asexual
• Sexual reproduction
• Most plants and organisms use sexual
  reproduction
ASEXUAL REPRODUCTION
UNIVERSAL GENETIC CODE

• Information needed to live and grow is stored in
  complex molecules called DNA
• DNA stores the information for genes and traits of an
  organism
• DNA is the method for passing down genetic
  information to the next generation
USE OF MATERIALS AND ENERGY

• Organisms must use materials from the earth and
  energy from the sun to live and grow

• Chemicals/Nutrients from the earth

• Energy from the sun helps plants and other
  photosynthetic organisms produce food
METABOLISM

• Living things need energy

• Life functions require energy

• Transforming energy from one form to another with
  in cells is metabolism
RESPOND TO THEIR ENVIRONMENT

• Organisms can detect and react to different signals
  within their environment

• Stimuli: signal to which an organism responds
EVOLVE OVER TIME

• Populations of organisms change over time

• Natural selection: Individuals more well suited for
  their environment will do better and will reproduce
  more then other individuals
CR:4

• What does it mean to be alive? Discuss what it
  means to you; think about the characteristics of life.

• Or

• Design an experiment: If you were given an
  unknown substance, what kinds of tests could you
  preform to find out if that item was living or non-
  living?
CHARACTERISTICS OF LIFE
            ASSIGNMENT
• Today you will explore all the characteristics of life
  for a single organism

• Pick any organism you would like, tell you instructor
  what you choose; grab paper, pencils, markers,
  whatever you would like to use

• Make a flow diagram of your organism fulfilling all
  the different characteristics of life.
SCIENTISTS OF BIOLOGY

• Zoologists: Animals

• Botanists: Plants

• Ethologists: Animal Behavior

• Paleontologists: Life in the past
LEVELS OF ORGANIZATION

•   Molecules
•   Cells
•   Groups of cells
•   Organism
•   Population community
•   Ecosystem
•   Biosphere
• CR:5
• Describe how you fulfill the 8
  characteristics of life. Use your
  notes if you can’t remember
  all 8.

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Unit 1 pp

  • 1. UNIT 1: INTRODUCTION TO BIOLOGY TIMBERLANE HIGH SCHOOL MEGHIN MARLEY
  • 2. WHAT IS SCIENCE? • An organized way of using evidence to learn about the natural world. • The word science can also be used to describe what humans already know about the natural world. • It’s important to avoid opinions and biases in science so actual facts can be presented.
  • 3. HOW DO HUMANS EXPLORE SCIENCE? • Observe • Describe • Experiment • Read • Research • Explore • What are some words or processes that come to mind when you think about exploring science?
  • 5. OBSERVATION • Involves observing something with one or more of your senses • Using your senses to gather information • Which senses do you believe would be most useful in gathering scientific information or data? • Sight • Sound • Touch • Smell • And sometimes even taste
  • 6. OBSERVATION • 1. Quantitative- involves numbers, counting or measuring • 2. Qualitative- observations that cannot be counted or measured • Observations are used in collecting data and the formation of evidence
  • 7. EVIDENCE INTERPRETATION • What happens after the observations are made? • How are the observations used to provide an understanding of the process you are trying to explain? • Inference: a logical explanation or interpretation based on prior knowledge/experience of the subject
  • 8. HOW ARE SCIENTIFIC IDEAS TESTED? • Once someone has formed a scientific question what is the next step? • The Scientific Method can be used to test a hypothesis.
  • 9. THE BASIC STEPS • 1. Ask a Question • 2. Form a Hypothesis • 3.Design and Conduct an Experiment • 4. Analyze Results of the Experiment • 5. Draw Conclusion
  • 10. THE SCIENTIFIC METHOD • http://www.youtube.com/watch?v=LMg_asQ3Hto
  • 11. HYPOTHESIS • Can answer a scientific question • Can describe scientific information • A possible explanation • Hypotheses can be tested usually through controlled experimentation • Sometimes hypotheses are wrong • In an If…then format
  • 12. ALTERNATIVE HYPOTHESES • H 1, H 2, H 3 • Alternative hypotheses are more likely to be correct • Multiple alternative hypotheses can be generated and tested.
  • 13. THE SCIENTIFIC METHOD • Monty Python • http://www.youtube.com/watch?v=k2MhMsLn9B0
  • 14. NULL HYPOTHESIS • H0 • The null hypothesis is a hypothesis which the researcher tries to disprove, reject or nullify • The 'null' often refers to the common view of something, while the alternative hypothesis is what the researcher really thinks is the cause of a phenomenon.
  • 15. THE STEPS • Do all scientific investigations include all the steps? • No • Do some investigations include more steps? • Yes • The scientific method is the basis for scientific investigation, but it is not set in stone. • It is a process to help direct scientific inquiry, more steps, research, or experimentation can be necessary.
  • 17. CR: 3 Why is the scientific method important for answering scientific questions? Do your best to describe the process of the scientific method step by step.
  • 18. THE PROCESS OF SCIENTIFIC INVESTIGATION • The Process of Scientific Investigation can be done in a series of stages, formal research and testing is carried out in this manor. • 1. Observations • 2. Form Hypotheses • 3. Predictions • 4. Experimentation • 5. Make conclusions
  • 19. EXPERIMENTAL DESIGN • Developing and setting up a controlled experiment to test your hypothesis • Controlled Experiment: When only one variable is changed at a time • Manipulated variable: variable that is deliberately changed • Responding variable: variable that is observed and changes in response to the manipulated variable
  • 20. MORE ON VARIABLES • Independent Variable- researcher can control, concentration of a chemical, timing of measurements • (manipulated variable) • Dependent Variable- response that is measured • (responding variable)
  • 21. CONTROLLED EXPERIMENTS • What does it mean to have a controlled experiment? • When an experiment is run, one variable is altered and the all other variables will remain constant. • A controlled experiment will be run the same way but no variables will be altered and all other variables will be kept constant.
  • 22. DRAWING CONCLUSIONS • Data from experiments is evaluated • The hypothesis is supported or rejected
  • 23. THEORIES • Once you have supported your hypothesis through testing does it become a theory? • What is a theory? • A theory is a well supported explanation involving a broad range of observations for a particular phenomenon • Multiple investigations have been done and proven the hypothesis to be true
  • 24. THEORIES • Theories can be widely excepted, but should not be considered absolute truth • New evidence may be uncovered • New technologies can lead to new discoveries
  • 25. REDI’S EXPERIMENT • In ancient times people did not understand many biological lifecycles, people accepted the idea that some organisms, fruit-flies, maggots, would suddenly just appear • Spontaneous Generation- sudden appearance of organisms from non-living matter
  • 26. REDI’S EXPERIMENT • In 1668 Francesco Redi observed flies on meat and several days later the appearance of maggot, he wanted to test his hypothesis that maggots came from flies and developed a controlled experiment. • He used 8 jars, 4 he left open to the air and 4 he covered with muslin, a fabric that prevented flies from getting to the meat.
  • 28. REDI’S EXPERIMENT • What was the control group? • The jars that were left uncovered • This was the way meat was typically kept • His hypothesis was that flies were causing the production of maggots on the meat • He was able to prove that the flies were causing the maggots by covering the jars, preventing the flies from laying eggs in the meat.
  • 29. VARIABLES IN REDI’S EXPERIMENT • Manipulated Variables: • Muslin covering the jars • Responding Variables: • The maggots appearing or not • Variables that were controlled: • Jars, type of meat, location, temperature, time
  • 30. JOHN NEEDHAM • Mid-1700’s • Englishman • Used a sealed jar of gravy to try and disprove Redi’s claim on spontaneous generation • He took a jar of gravy and sealed it • He then heated the gravy “killing off all possible microorganisms” • After several days he examined the gravy, found microorganisms and claimed they could have only came from the gravy, since the jar was sealed.
  • 31. JOHN NEEDHAM • Why do you think there were organisms in the gravy? • Do you think Needham’s findings disproved the work of Redi? • Was Needham’s experiment controlled?
  • 32. SPALLANZANI’S EXPERIEMENT • Italian Scholar • An improvement on Needham’s experiment • He believed that the gravy had not been heated enough to kill all the existing microorganisms • Preformed a similar experiment to Redi’s
  • 33.
  • 34. SPALLANZANI’S EXPERIMENT • Spallanzani claimed that the gravy left open grew microorganisms that had entered from the air, the sealed flask had no living organisms. • He concluded that non-living gravy could not produce living things • What was the control group in Spallanzani’s experiment? • Gravy flask left unsealed • The manipulated variable was the sealing of the flask • The responding variable was microorganism growth • He sealed the flask and prevented microorganism growth
  • 35. LOUIS PASTEUR • Famous problem solver, Microbiologist • In 1864 Louis Pasteur designed a flask with a curved neck so that air could get into the flask, but microorganisms could not • Other works of Pasteur • Saved French wine industry when wine was souring • Saved the silk industry through discovery of a silkworm disease • Discovered and worked with infectious diseases • Vaccine for Anthrax bacterial infection in 1881
  • 38. CAN EVERYTHING SCIENTIFIC BE TESTED BY EXPERIMENTATION? • Animal and insect life cycles • The Great White Shark is hard to keep in captivity • Ecological Interactions • How do you simulate all the different environmental factors in a controlled way? • Human Ethics • Stem cell research • Testing on humans and animals
  • 39. ALTERNATIVES TO CONTROLLED EXPERIMENTS • Field Studies • Observation of animals or other living things in their natural environment • Studies involving large amounts of people or subjects • More samples gives more reliable data • Control of as many factors as possible • In a medical study for cancer, people with other health issues may be eliminated • It is important to research what is already out there. What has been done on the subject? • Cite your sources!
  • 40. So how are we going to use this information about science and the process of scientific investigation to learn about Biology?
  • 41. SO WHAT IS BIOLOGY? • Textbook definition: A field of science that seeks to understand the living world. The study of life. • The study of things that are “living”. • What does it mean to be “alive”? • What are some characteristics that help people determine whether something is living or non?
  • 45.
  • 46. THE CHARACTERISTICS OF LIFE • Made up of units called cells • Maintain stable internal conditions: homeostasis • Grow and develop • Reproduce • Based on a universal genetic code • Obtain and use materials and energy • Respond to their environment • When looking at a species as a whole, living things can change over time or evolve
  • 47. THE CELL • What is a Cell? • A cell is a collection of living matter surrounded by a membrane that separates it from its surrounding environment. • How are cells organized?
  • 50. CELLULAR ORGANIZATION • All living things are made up of one or more cells • Cells can be simple to very complex • Cells can grow and reproduce • Single-Celled Organisms • Algae • Bacteria • Paramecia, A protist • There are around 100 trillion cells in the human body
  • 51. HOMEOSTASIS • Living things must expend energy to keep their cells within certain limits for proper form and function • Organisms are able to maintain certain internal environments even when the environment outside of them is constantly changing • An organism's ability to do this allows them to survive
  • 53. GROWTH & DEVELOPMENT • Every different organism has a specific pattern of growth • A single egg cell once fertilized can divide over and over • Cells differentiate forming tissues and organs
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  • 55.
  • 57. REPRODUCTION • The reproduction of new generations • Asexual • Sexual reproduction • Most plants and organisms use sexual reproduction
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  • 60. UNIVERSAL GENETIC CODE • Information needed to live and grow is stored in complex molecules called DNA • DNA stores the information for genes and traits of an organism • DNA is the method for passing down genetic information to the next generation
  • 61. USE OF MATERIALS AND ENERGY • Organisms must use materials from the earth and energy from the sun to live and grow • Chemicals/Nutrients from the earth • Energy from the sun helps plants and other photosynthetic organisms produce food
  • 62. METABOLISM • Living things need energy • Life functions require energy • Transforming energy from one form to another with in cells is metabolism
  • 63. RESPOND TO THEIR ENVIRONMENT • Organisms can detect and react to different signals within their environment • Stimuli: signal to which an organism responds
  • 64. EVOLVE OVER TIME • Populations of organisms change over time • Natural selection: Individuals more well suited for their environment will do better and will reproduce more then other individuals
  • 65. CR:4 • What does it mean to be alive? Discuss what it means to you; think about the characteristics of life. • Or • Design an experiment: If you were given an unknown substance, what kinds of tests could you preform to find out if that item was living or non- living?
  • 66. CHARACTERISTICS OF LIFE ASSIGNMENT • Today you will explore all the characteristics of life for a single organism • Pick any organism you would like, tell you instructor what you choose; grab paper, pencils, markers, whatever you would like to use • Make a flow diagram of your organism fulfilling all the different characteristics of life.
  • 67. SCIENTISTS OF BIOLOGY • Zoologists: Animals • Botanists: Plants • Ethologists: Animal Behavior • Paleontologists: Life in the past
  • 68. LEVELS OF ORGANIZATION • Molecules • Cells • Groups of cells • Organism • Population community • Ecosystem • Biosphere
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  • 70. • CR:5 • Describe how you fulfill the 8 characteristics of life. Use your notes if you can’t remember all 8.