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1 of 10
Most common
manifestation of
thyroid disease

www.medicinemcq.com

1
Enlargement

of

the thyroid

www.medicinemcq.com

2
1.

Is the goiter diffuse or
nodular?
2. Is it nontoxic or toxic?
3. Is it causing any local
compressive or cosmetic
problems?
4. Is it benign or malignant?
www.medicinemcq.com

3
Diffuse

goiter
Multinodular goiter
Solitary nodule

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4
 Iodine

deficiency (endemic goiter)
 Simple goiter
 Hashimoto's thyroiditis
 Graves' disease
 Transient thyroiditis
 Drugs


Iodine, amiodarone, lithium

 Suppurative

thyroiditis
 Dyshormonogenesis
 Riedel's thyroiditis
www.medicinemcq.com

5
 Colloid

nodule - most common and do
not have an increased risk of
malignancy
 Simple cyst
 Follicular adenoma - Most follicular
adenomas are benign
 Carcinoma
 Lymphoma
 Thyroiditis
www.medicinemcq.com

6
 Most

common cause - dietary
iodine deficiency
 Impaired

synthesis of thyroid hormone
 Compensatory rise in the serum TSH
 Hypertrophy and hyperplasia of
thyroid follicular cells
 Euthyroid state

www.medicinemcq.com

7
Diffuse

nontoxic (simple)

goiter
 enlarged

follicles filled with

colloid
 also called colloid goiter

www.medicinemcq.com

8
 With

time, recurrent episodes of
hyperplasia and involution
 irregular

enlargement of the thyroid
and nodule formation
 thyroid nodule - a lesion in the thyroid
gland due to an abnormal focal growth
of thyroid cells
 All

long-standing simple goiters
convert into multinodular goiters
www.medicinemcq.com

9
No

physiologic increase
in thyroid volume
Goiter during
adolescence is pathologic
For rest of the slides visit www.medicinemcq.com > Thyroid

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10

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Thyroid - Goiter