1. EuropeanYear of Creativity and InnovationSantander – UIMP 20 – 21 Augustus 2009KeyCompetencesfortimes of crisis “Sense of Initiative and Entrepreneurship” Dr Martin Hinoul Business Development Manager KnowledgeEconomyRegion Leuven Santander, August 20, 2009

2. AnEntrepreneurial Society “The rise of the entrepreneur, which has been gathering speed over the past 30 years, is notjustabouteconomics. Italsoreflectsprofoundchanges in attitudes to everythingfromindividualcareers to the social contract. Itsignals the birth of anentrepreneurial society” -The Economist- March 14, 2009

3. The World became Flat…(Friedman)

4. EU - U.S EU EU - U.S – Asia- BRIC And the business becameglobal… 60 trillion$ MarketValue GDP year 2000 1900 0.5 billion 1 billion 2 billion customers

5. The World becameFlat, but … Europe has norawmaterials

6. And Europe has noenergy resources

8. From Productivity to Innovation

9. "The literature on innovation is longer than my arm. (…) It can be summarized as follows : innovation is either a machine or a magic garden. If it's a machine, companies should design it, oil it, power it up, and manage it. If it's a garden, companies should create conditions under which it can flourish, and then let the magic occur. Innovation is both of course." -Thomas A. Stewart (*)- Fortune magazine, 5 mars 2001 (*) : Author of "Intellectual capital – The new wealth of organizations", Nicholas Brealey Publishing, 1997

11. Education

12. Innovation

13. ICT Belgium Source: World Bank Institute

14. “In the twenty-firstcentury, brainpower and imagination, invention, and the organization of newtechnologies are the keystrategicingredients.” - Lester Thurow- Professor MIT -

15. 12 “ In a knowledge-based economy growth is inextricably linked to the capacity for innovation – the ability to transform knowledge and ideas into new products, processes or services. Healthy and innovative regional economies are the foundation of a nation’s competitiveness” -Deborah L. Wince-Smith President Council on Competitiveness

16. The New Economyor the knowledgeeconomyregions

17. The EuropeanTechnology Dilemma The technology gap (10 yrs) with the US is still not decreasing The technology gap with China and India (20 yrs) is shrinking every month

18. FromLisbon 2000 to… 70% of the activepopulationshouldbeemployed 3% of GDP should go to R&D And Europeshouldbe the strongestKnowledgeEconomy in the world

19. Innovation and Lisbon 2010 New faces – Results?

20. Innovation is changing

21. Faster, Faster, Faster

22. 19 Source: Joseph Jacobsen

23. Itrequires a widercollaborationacross disciplines and specialties (multidisciplinaryapproach)

24. 21

25. The concept of IntellectualPropertyis beingreexamined in the light of these collaborativedemands

26. Intellectual Property

27. Itrequires a widercollaboration of KnowledgeEconomyregions

28. Taiwan SiliconValley China ThreeRegional Centers growingtogether, increasing the overall size of the pie

29. Collaboration of KnowledgeEconomyRegions

30. The trend is clearlytowards “openinnovation”

31. The guru of Open Innovation – Henry Chesbrough

32. Innovationrequires the “triplehelix” approach

33. The Triple Helix Is the complex betweenthreeactors The Government The Industry The Knowledge Centers "dynamics"

34. Triple Helix is about: Knowledgecreation Knowledgediffusion Knowledgeexploitation

35. In Conclusion: Faster, Faster, Faster Itrequireswidercollaborationacross disciplines and specialties (multidisciplinaryapproach) The concept of intellectualproperty is beingreexamined in the light of these collaborativedemands Itrequires a widercollaboration of regions The trend is towards “openinnovation” Itrequires a “triplehelix” approach

36. NeedforanIntegratedPerspectiveonInnovation 33

37. 1. Innovation is about :

39. 2. Innovation is about :

40. 3. Innovation is about :

41. 4. Innovation is about :

42. The EuropeanTechnology DilemmaUS versus Europe The technology gap (10 yrs) with the US is still not decreasing

43. 40 A nation which depends upon others for its new basic scientific knowledge will be slow in its industrial progress and weak in its competitive position in world trade Science, the endless frontier – Vannevar Bush 1945

44. Old and New Halls of Fame  Seattle      Pittsburg      San Diego 

45. SiliconValley

46. It is a new Form of Culture All things are possible attitude Risk Taking Scott McNealy-Sun Co-competition Stockoptions BasedonMeritocracy Repeaters (Reinvention) Time for the nextbigthing CULTURE Cross-pollination Inflection Point (Andy Grove) Cross-investments Stateofmind Networking FailureBadgeofmerit Jumping on theNextCurve (Oracle)

47. “The story of Silicon Valley is not “e,” but “i,”, not electronic commerce but innovation and imagination. What distinguishes many of these companies is not their technical prowess but their imagination. They are young, hungry, and totally devoid of tradition. It is the power of “i,”, rather than “e,” that separates the winners from the losers in the twenty-first-century economy.” “Silicon Valley is not a place, but a metaphor for unfettered imagination, rampant experimentation, and an utter lack of nostalgia.” Leading the Revolution Gary Hamel

48. Silicon Valley – A complex Network of Clusters VC – Kleiner Perkins Caulfield…NASDAQ Nano-electronics Route 101 – Route 280 - State of mind Silicon Valley Joint Venture Network Stanford University – UCSF - Berkley Internet – Google – e-Bay –Yahoo-Amazon.com Networks – Cisco (Bosack,Lerner& Troiano -1984) Software -Oracle Computers – Apple - Sun Semiconductors – Shockley - Intel Electronics – Hewlett Packard - Varian Clean Technology 2005 2000 1980 1975 1955 1939 Stanford – Fred Terman

49. Sig en Rus Varian Hewlett&Packard Shockley Steve Jobs Larry Page Sergey Brin Larry Ellison S. Boyer Scott McNeally Pierre Omidyar Terman John Chambers Gordon Campbell Jeff Bezos Edw. McCracken Jerry Sanders Jerry Yang A network of professors, entrepreneurs, venture capitalists, Nobel Prize winners and role models

50. Silicon Valley Is a “network” and a “state of mind” (Felix Theeuwes – Durect Corporation) Is a network effect that transcends national boundaries (Wim Roelandts – voorzitter Xilinx) Regional centers growing together increasing the overall “Pie” (Wim Roelandts Xilinx) Stanford University 1891

51. TwoExamples Steve Jobs – Apple Computer Larry Page & SergeyBrin - Google 48

52. Steve Jobs and Apple

53. Steve Jobs – Apple Computer (1) “Mr Jobs is most celebratedforhissense of product design, his marketing acumen and, especially, hisability to executeonvisionsthat have transformedthree industries: personalcomputing, music and telephones.” - Financial Times- July 2009 50

54. Larry Page & SergeyBrin – Google (2) “Moscow -bornSergeyBrin and Midwest-born Larry Page dropped out of graduate school at StanfordUniversity to, in theirownwords, “change the world” through a powerful search engine thatwouldorganizeevery bit of informationon the Web for free. The Google Story takesyoudeepinside the company’s wild ridefromanideathatstruggledforfunding in 1998 to a firmthatrakes in billions in profits, makingBrin and Page the wealthiestyoung men in America.Basedonscrupulous research and extraordinaryaccess to Google, thisfast-movingnarrativerevealshowanunorthodox management style and culture of innovationenabled a search engine to shake up Madison Avenue and Wall Street” -The Google Story- David A. Vise 51

55. Larry Page and Sergey Brin

56. The Google Story

57. The EuropeanTechnology DilemmaEurope versus Asia The technology gap with China and India (20 yrs) is shrinking every month

58. Knowledge Economy Regions in Asia        

61. India, a Rising Elephant

62. From terracotta statues in Xi’an (emperorQinShi) to …

63. …a neweconomicsuperpower?

64. WhichSuperpower?

65. And what about good old Europe?

66.      European Knowledge Economy Regions    * ?                 

67.   European Knowledge Economy Regions        ?                 

70. Cambridge the betterexample in Europe

72. The East of England RegionSilicon Valley Scale – Lots of space for Growth Cambridge source: Cambridge 2020 report - 1998

73. The ‘Golden Triangle’ of the UK “…the only way to compete is to concentrate resources in regions that are strong….” Martin Rigby. MD, ET Capital, Cambridge Lecture, 2006 Some 75% of all VC funds found a home here in 2006 Cambridge Along the M11 O2C Arc – IP Ally ‘HugeBrainpower’ Stansted and the ‘Herts’ Pharmas London: ‘Finance and Global Connections’ (plus its Universities) Oxford Down the A34 Global connectivity Thames Valley ‘Industry and Commercialisation’ Heathrow ‘Growth Area’

74. Leuven

76. The Leuven ModelKnowledge Transfer and Collaboration

77. In an old young city

78. Some important data for the Leuven Region 1366 Brewery Stella Artois (nowInbev) 1425 University of Leuven 1972 KU Leuven R&D 1984 IMEC 1997 Gemma FrisiusFund

80. Entrepreneurs & Role Models

81. Money

82. Capital Markets

83. Infrastructure

84. Cluster Policy

85. Presence of International Companies

86. Networks

87. Government

88. Quality of Life* Gibbons – Saxenian - Hinoul

89. Transfer Cell K.U.Leuven R&D

91. Columbia University (USA)

92. Imperial Innovations (UK)

93. MIT (USA)

97. STMicroelectronics IMEC Imec and the World’s Largest Industry Commitment to Semiconductor Research in Partnership

98. Mechatronica E-security Feed – food - health L-SEC Leuven.Inc DSP-Valley Telematica Communicatie Life sciences Micro-elektronica Nanotechnologie Cluster Policy

99. Theconcept Region Economy Ingredients

100. The Old Economy Region Economy Universiteit Ingredients INBEV KBC-groep

101. The New Economy Region Economy Ingredients Companies

102. Region Economy Ingredients Clusters Sweepers andRecipe Cluster Formation

103. Martin Hinoul’s Bouillabaisse Ingredients and Recipe SourceFortune – Sept 26,2005 Campbell Soup 1935

104. Kenniscentra Eyetronics Telindus B.E.S.T. TycoElectronics Newfrom Centers of excellence A.C.S. Belgium OptionInternational Resonext CypressSemi ARM Luciad EonicSystems FillFactory Assurcard Vivactiss K.U.Leuven Lab Photochemistry & Spectroscopy Lab of Solid-state Physics & Magnetism STM Tomoton ICOSVision Systems AgilentTechn. JSRElectronics J.W.Lemmens KULeuven IMEC MicroMatic VectorInternational IPCOS Photovoltec PhilipsITCL Xenics IMEC Sub-45nm research facility Nanotechnology Platform Design platform Septentrio Delcomp Oligosense Pure innovatieve bedrijven ASMBelgium Krypton EpiqSensorNite Data4S TargetCompilerTechn. AnSem Soltech Easics CoWare Mixed innovatieve bedrijven MindLinux Solutions LMS Micro-elektronica - nanotechnologie

105. Life sciences in Leuven Kenniscentra E.S.R.I. Deckers Div BiotestSeralco Benelux Dermat Thrombogenics Centers of excellence Terumo Europe Tigenix ReMynd IDT(RNA-TEC) Dakocytomation BioTieTherapies Corp. Norgine Univhospitals K.U.Leuven RegaInstitute CEHA Lab of Exp. Genetics & Transgenese Cochlear Algonomics M-Elect Autocyte Europe PatientWeb M4S Medvision Benelux K.U.Leuven L-MTC Materialise Neurogenetics QMedit @MedicalTechn. MXS VIB VIGOUR IVIA Custom8 Onco Methylome Puurinnovatieve bedrijven Conti BPC Fugeia Regenesys Diatos New Standard Eng. Medicim Malaise&co Ortec Formac Pharmaceuticals CMPG Gemengdinnovatieve bedrijven Centocor VWR International

106. Quality of Life

107. 12 Lessons from Leuven Basis is acriticalmass of high qualityresearch - Knowledge Createanappropriateentrepreneurialclimate in a university context Create a legalframeworkwith respect to exploitation of academic research Clearincentivesandpolicies to encourage research groups and departments to activelyseekknowledge transfer opportunities Create a professionalInterfaceUnit – AnIntegratedapproachon research valorisation: multidisciplinary team & “high value” services Create a SeedCapital and/or Venture CapitalFund

108. 12 Lessons from Leuven Fosterspin-offsfromyouruniversity research Clearownership of IntellectualProperty Improvingawarenessamongfederal, regional and localshareholders Supporting aforumfor business, academia, government and supportingorganisations to build partnerships bysharingnewideas and best practices. Importance of the networks. Focuson Focus and Enthusiasm Quality of life

109. The Eindhoven – Leuven – Aachen Growth ModelELAt

111. A European Region with Critical Mass

114. Entrepreneurs & Role Models

115. Money

116. Capital Markets

117. Infrastructure

118. Cluster Policy

119. Presence of International Companies

120. Networks

121. Government

122. Quality of LifeQuality of life Capital Markets Infrastructure

123. Knowledge Centres Quality of life Capital markets Knowledge Centres

124. Close to the 3% Lisbon target ?

125. Infrastructures Capital markets Quality of life

126. The Leuven Knowledge Pearl

127. High Tech campus Eindhoven

128. The DSM – Chemelot High Tech Campus

130. 10.000 new jobs

132. Prospects for the futureHow science will revolutionize the 21st century

134. Jack Kilby – Integrated Circuit

136. Shockley1955

137. Fairchild1957

141. 114 There is plenty of room at the bottomRichard Feynman 35 Xenon atoms on a Ni substrate

142. 115 Bio Silicon – Bio Informatics (1st decade)

143. 116 Nanoshells Naomi Halas – Rice University

145. Opsporen van virussen en andere organismen, stofdeeltjes en plantensporen

146. Budgetten van NIH en Center for disease control and prevention

147. Juli 2004 Bio Shield-project

149. Chemische fabriek op uw bureau Het samenpersen van een chemisch productieproces op een plaatje zo groot als een creditcard (Process on a Chip, PoaC). Extreme veiligheid, veel kleiner, selectiever, mogelijkheid voor nieuwe produkten. Japans consortium van 25 universiteiten en 40 bedrijven heeft haalbaarheid aangetoond van een emulsiepolymerisatieproces.

150. Nano-robot

152. Thomas Edison & Georges Eastman (1928)