Product Spec Sheet for Proliposome formulation manufactured by Encapsula NanoSciences that is used specifically in the cosmetic industry. The brand name is Dermasome-Res (NE). The Dermasome-Res (NE) formulation is composed of unsaturated phospholipids and it does not contain alcohol. The proliposome formulation forms liposomes upon dilution with water. During the dilution process water soluble active ingredients can be encapsulated inside the liposomes or liposoluble active ingredients can be incorporated into the lipid bilayers. The formulation is packaged under sterile conditions inside spout pouches.

1. DERMESOMETM-RES
(NE)
CHARACTERISTICS
DermasomeTM –Res (NE) is an alcohol (ethanol) free
proliposome formulation for cosmetic formulators
that form nano-sized liposomes upon dilution of the
formulation with water using standard mixing
devices.
DermasomeTM –Res (NE) is composed of high purity
phospholipids that form stable liposomes with high
encapsulation and incorporation efficiency. The
formulation is colorless and odorless.
DermasomeTM –Res (NE) is composed of a proprietary
blend of unsaturated phospholipids.
Hydration of these lipids with water causes
rearrangement of the lipid bilayers which
spontaneously forms liposomes. If water-soluble
active ingredients, such as peptides, minerals or
other water soluble molecules, are dissolved in water
and added to DermasomeTM –Res (NE), liposomes
with high entrapment of the active molecule are
formed. If liposoluble molecules or antioxidants are
added to DermasomeTM –Res (NE) and hydrated with
water, the lipid soluble molecules will be
incorporated into the lipid bilayers of the liposomes.
Up to 65% of a water-soluble molecule in the solution
is encapsulated inside the liposomes and almost
100% of liposoluble molecules are incorporated into
the lipid bilayers of the liposomes.
Since the lipids that are used in the formulation are
unsaturated, the formulation does not require
heating after hydration. Therefore heat sensitive
active ingredients can be used with DermasomeTM –
Res (NE).
INCI NAME
WATER (and) BUTYLENE GLYCOL (and) GLYCERINE
(and) LECITHIN (and) RESVERATROL
QUICK FACTS
DermasomeTM products are made
from unsaturated phospholipids and
are used in processes that do not
require heating.
If the active ingredient is
temperature sensitive then use the
DermasomeTM product line.
*NE Stands for non-ethanol based
formulation
6 Cadillac Dr, Suite 245
Brentwood, TN 37027
United States of America
1-(800) 387-0620
info@encapsula.com
/company/encapsula-nanosciences-
llc
DISCLAIMER
Any formulation suggestions or
technical information is based on our
knowledge on the basis of current
s cientific data and publications.
Encapsula is only a raw ingredient
manufacturer and cannot accept any
l iabilities for products manufactured
by others . Every manufacturer and
formulator is responsible for
compl iance with all s tatutory
regulations including those in the field
of patent legislation.

2. COMPOSITION
Phospholipids 20%
and Resveratrol
Hydrophilic medium 80%
ANALYTICAL DATA
Peroxide value Max. 5
PH (pur) 5-7
MICROBIOLOGICAL DATA
Yeasts/g absence
Molds/g absence
S. aureus / C. albicans absence
and P. aeruginosa/g
PHYSIO-CHIMICAL PROPERTIES
Appearance: White, milky
Miscibility Form liposomes spontaneously at
Room temperature after addition of
Water.
STORAGE CONDITION
Stable for 24 months in its original closed packaging
below 8℃ (preferred to be kept in refrigerator).
Reclose container immediately after use and protect
from direct sunlight. If container is opened, keep
container in refrigerator at 4℃ and use within 3
months.
REGULATORY STATUS
No specific regulation
PACKAGING
2 oz, 18 oz, 1 Gallon
DERMESOMETM-RES
(NE)
QUICK FACTS
DermasomeTM products are made
from unsaturated phospholipids and
are used in processes that do not
require heating.
If the active ingredient is
temperature sensitive then use the
DermasomeTM product line.
*NE Stands for non-ethanol based
formulation
6 Cadillac Dr, Suite 245
Brentwood, TN 37027
United States of America
1-(800) 387-0620
info@encapsula.com
/company/encapsula-nanosciences-
llc
DISCLAIMER
Any formulation suggestions or
technical information is based on our
knowledge on the basis of current
s cientific data and publications.
Encapsula is only a raw ingredient
manufacturer and cannot accept any
l iabilities for products manufactured
by others . Every manufacturer and
formulator is responsible for
compl iance with all s tatutory
regulations including those in the field
of patent legislation.