This are the slides for my lightning talk at SciFoo 2010. A full description of the talk can be found in http://buildingblogsofscience.wordpress.com

1. http://www.flickr.com/photos/la_hire/4718503190 http://www.flickr.com/photos/la_hire/4718598788

2. Standing on the shoulders... (of people of different sizes) http://www.flickr.com/photos/sunlightfoundation/2385174105

3. Curtis, HJ and Cole KS (1942) Membrane Resting and Action Potentials from the Squid Giant Axon. Journal of Cellular and Comparative Physiology Vol 19 (2) 135-144

4. Curtis, HJ and Cole KS (1942) Membrane Resting and Action Potentials from the Squid Giant Axon. Journal of Cellular and Comparative Physiology Vol 19 (2) 135-144 In order to vary the potassium ion concentration, [...] potassium was substituted for sodium, or vice versa.

5. Hodgkin AL and Katz B (1949) The effect of Sodium Ions on the Electrical Activity of the Giant Axon of the Squid. J. Physiol. 108, 37-77

6. ‘ 4. These results support the view that depolarization leads to a rapid increase in permeability which allows sodium ions to move in either direction through the membrane. ‘ Hodgkin AL and Huxkley AF (1952) Currents carried by Sodium and Potassium ions Through the Membrane of the Giant Axon of Loligo. J. Physiol. 116, 449-472

7. Science 18 February 1972 Vol. 175. no. 4023, pp. 720 - 731 DOI: 10.1126/science.175.4023.720

8. Journal of Morphology (1918) Volume 31, issue 2, 293-315

9. Nature. 1989 Feb 2;337(6206):424-8.

10. Nature 353 , 861 - 864 (31 October 1991) doi:10.1038/353861a0

11. (1977) http:// ecx.images-amazon.com/images/I/419XB2PP65L.jpg

12. For the past 100 years or so we have been basically confirming Cajal’s ideas. Barbara Fredette

13. Celio, MR, Spereafico R, De Biasi S and Vitellaro-Zuccarello L. (1998) Perineuronal nets: past and present . TINS 21: 510-515 ‘ However, regarding this issue the last word has not been said.’ S Ramón y Cajal, 1910 Histología Normal. (my own translation)

14. “ The mature ECM is thus inhibitory for experience-dependent plasticity, and degradation of CSPGs reactivates cortical plasticity.” Science 8 November 2002: Vol. 298. no. 5596, pp. 1248 -1251 DOI: 10.1126/science.1072699

15. http://www.edge.org/documents/archive/images/wwb-l.jpg 2006 “ My hunch is that the substrate of old memories is located not inside the cell but outside in the extracellular space.” Terrence Sejnowski

16. http://www.anat.ucl.ac.uk/research/linden/cajal_actx_inter.jpg

17. Nature 408 , 361-365 (16 November 2000) | doi:10.1038/35042582

18. Mr. Glen MacDonald - Virginia Merrill Bloedel Hearing Research Center, University of Washington Seattle, WA, USA -Specimen: Mammalian Inner Ear http://www.olympusbioscapes.com/gallery/2007/index.html

19. Hagmann P, Cammoun L, Gigandet X, Meuli R, Honey CJ, et al. 2008 Mapping the Structural Core of Human Cerebral Cortex. PLoS Biol 6(7): e159. doi:10.1371/journal.pbio.0060159

20. “ Excercise Determine the limits of an object or event Determine the limit more precisely Repeat, until further precision is impossible” 1963 - George Brecht (1926-2008) (Seen at Walker Art Center, Minneapolis MN)