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IVF laboratory Design kosmogonia hellas
“  Your IVF program is only as good as the lab which supports it  “ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Formaldehyde Furniture:  Upholstered furniture, carpets,plywood, pressed wood products 1,4-dichlorobenzene, naphthalene Air fresheners:  Moth balls, deoderizers,  Freons (trichlorofluoromethane, dichlorodimethane) Refrigerant:  air conditioners, freezers, dehumidifiers Tetrahydrofuran, cyclohexane, methyl ethyl ketone, toluene, acetone, hexane, 1,1,1-trichloroethane Adhesives:  PVC cement, contact cement, model cement Tetrachloroethene, perchloroethene, trichloroethene Fabric cleaners:  Dry cleaned clothes, stain removers, leather cleaners Acetone, ethyl alcohol, isopropyl alcohol, methacrylates, ethyl acetate Personal care products : nail polish & remover, colognes, hair spray BTEX (benzene, toluene, ethylbenzene), hexane, cyclohexane, 1,2,4-trimeyhylbenzene Petroleum distillates:  Paint thinner, oil-based paints, liquid insect pest products, furniture polishes Possible VOCs Products used in Home and work
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Air Quality and Regulations
Updated 2008, EU GMP Annex 1-Manufacture of Sterile Medical Products Cleanroom classification ISO classification   Not defined 29 000 3 520 000 D 29 000 3 520 000 ( 8 ) 2 900 352 000 ( 7 ) C 2 900 352 000 ( 7 ) 29 3 520 ( 5 ) B 20 3 520 ( 5 ) 20 3 520 ( 5 ) A 5  μ m 0.5 μ m 5  μ m 0.5 μ m Grade In operation At rest Max. permitted number of particles per m 3  equal to or greater than the tabulated size
 
Clean Room ,[object Object],[object Object],[object Object]
Clean Room ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Laboratory dress code ,[object Object],[object Object],[object Object]
Paints & Adhesives ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Paints & Adhesives ,[object Object],[object Object],[object Object],[object Object],[object Object]
Renovation of Laboratory ,[object Object],[object Object],[object Object],[object Object]
Renovation of Laboratory ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Unseen Dangers ,[object Object],[object Object],[object Object],[object Object]
On site supervision is essential
Chemicals detected in laboratory renovation (Athens 2009) *
IVF Outcome ,[object Object],[object Object],[object Object],[object Object],[object Object]
Maintaining good air quality  good laboratory practice  ,[object Object],[object Object],[object Object],1AB 2BB 4BB
Maintaining good air quality  Particle Monitors & VOC counters 1AB 2BB 4BB
Maintaining good air quality  Environmental Monitoring ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],1AB 2BB 4BB
Embryologists ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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IVF Lab. design

  • 1. IVF laboratory Design kosmogonia hellas
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  • 5. Formaldehyde Furniture: Upholstered furniture, carpets,plywood, pressed wood products 1,4-dichlorobenzene, naphthalene Air fresheners: Moth balls, deoderizers, Freons (trichlorofluoromethane, dichlorodimethane) Refrigerant: air conditioners, freezers, dehumidifiers Tetrahydrofuran, cyclohexane, methyl ethyl ketone, toluene, acetone, hexane, 1,1,1-trichloroethane Adhesives: PVC cement, contact cement, model cement Tetrachloroethene, perchloroethene, trichloroethene Fabric cleaners: Dry cleaned clothes, stain removers, leather cleaners Acetone, ethyl alcohol, isopropyl alcohol, methacrylates, ethyl acetate Personal care products : nail polish & remover, colognes, hair spray BTEX (benzene, toluene, ethylbenzene), hexane, cyclohexane, 1,2,4-trimeyhylbenzene Petroleum distillates: Paint thinner, oil-based paints, liquid insect pest products, furniture polishes Possible VOCs Products used in Home and work
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  • 8. Updated 2008, EU GMP Annex 1-Manufacture of Sterile Medical Products Cleanroom classification ISO classification Not defined 29 000 3 520 000 D 29 000 3 520 000 ( 8 ) 2 900 352 000 ( 7 ) C 2 900 352 000 ( 7 ) 29 3 520 ( 5 ) B 20 3 520 ( 5 ) 20 3 520 ( 5 ) A 5 μ m 0.5 μ m 5 μ m 0.5 μ m Grade In operation At rest Max. permitted number of particles per m 3 equal to or greater than the tabulated size
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  • 18. On site supervision is essential
  • 19. Chemicals detected in laboratory renovation (Athens 2009) *
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  • 22. Maintaining good air quality Particle Monitors & VOC counters 1AB 2BB 4BB
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Editor's Notes

  1. Recent developments- effecting the way we work, changing the way we have to think..growing evidence of air quality
  2. Our job to culture the perfect embryo-1 embryo,one healthy child
  3. Effect all unit…….Factors effecting are quality, personnel,goods glue paints
  4. Also incubators separate power line
  5. Embryo graded 1-5 PN on day1 Cleavage patterns Rate of first cleavage Blastocyst development, cell number, rate, inner cell mass aneuploidy
  6. Embryo graded 1-5 PN on day1 Cleavage patterns Rate of first cleavage Blastocyst development, cell number, rate, inner cell mass aneuploidy