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Strengthening the Delivery of Key Malaria
Control Interventions through Patent
Medicine Vendors in Nigeria



   Oladimeji Oladepo

   Country Coordinator
   Future Health Systems (Nigeria)
   University of Ibadan

   Beyond Scaling Up-May 24-26, 2010
                  Oladepo_ Strengthening Malaria Control Interventions
                                through PMVs- Nigeria                    1
Oladepo _ Involvement of PMVs in Malaria
                                 control
                2
The Central Question


Why
involve
PMVs in
malaria
control
services
?

           Oladepo _Involvement of PMVs in Malaria
                           control                   3
 Very high Malaria burden
   Nigeria contributes ~25% of the total African
    malaria morbidity and mortality burden
     Estimated 57.5 million cases and 225,000
      deaths (25% of global malaria burden; WHO
      2008)
     11% of maternal and 29% of under five
      death is due to malaria
     Malaria is intricately linked with
      poverty (significant drain on the economy
       and wellbeing)

                Oladepo _ Involvement of PMVs in Malaria control

                                     4
Fig 1: Major Communicable Diseases in Nigeria , 2005




(Source Erinoso, 2010)




                                             Oladepo _Involvement of PMVs in Malaria
   5                                                                         control
 Low coverage of ACTs, first-line
  drug
   ACTs most effective form of Medicine
    for treating malaria, yet ……
     access through Public Sector is highly limited
     Quantity stocked or sold by PMVs is very low
         8.5% of PMVs stocked ACTs compared to
          32.1 for monotherapy and 71.7 for
          Chloroquine (Oladepo et al,2007)
   Overall ACT access in Nigeria remains critically
    low with a projected gap of 80 % stretching
    through 2011(AMFM,2010)
                 Oladepo _ Involvement of PMVs in Malaria
                                                  control
                                 6
Projected gap in ACTs till 2011(Source AMFM, 2010)

         Children <5 Receiving                       2008 ACT Need and Gap
          an ACT Within 24hrs       MN
 %
 90%                                100
                                               89.5             6
 80%                                                                       11.5
 70%                                                                              71.9
 60%

 50%
                                      50
 40%                                                                                      ~80% of
                                                                                          need not
 30%
                                                                                          covered
 20%

 10%

 0%                                    0
       2007   2008      2011                Total ACT Dist. in                    Gap
       MICS   18 GF    Target                                                            Dist. in
                                             Need to   public
              States                                                                     private
                                            Cover Pop. sector
                                 Oladepo_ Involvement of PMVs in Malaria
                                                                                         sector
                                                                 control
                                                                                                7O
 Untapped capacity of PMVs in Anti-
  malarial Medicine provision
   PMVs remain the first point of call seeking
    treatment for fevers in Nigeria (Salako, Brieger,
     Afolabi, Umeh, & Agomo, 2001)

   High level of patronage (up to 70%)
   Used even when supposedly more
    convenient and cheaper alternatives exist
    (e.g PHC centres,Village health workers)(Brieger, Salako, Umeh,
     Agomo, Afolabi & Adeneye, 2002-3; Kaseje, Spencer& Sempebwa, 1987)

   The most common item stocked by PMVs is
    anti- malarias (ACTWATCH,2010)
                          Oladepo _ Involvement of PMVs in Malaria
                                                           control

                                          8
Proportion of the total volume of all anti-malarials sold or
      distributed in the 1 week preceding the ACTwatch survey


(Source ACTWATCH, 2010)




                                                   Oladepo _Involvement of PMVs in
  9                                                                 Malaria control
 Despite existence of supportive
  policy documents, access of
  poor people to quality anti-
  malarial services remains low
   government approved policies
      Investment in pro-poor programs targeting
       malaria(NEEDS)
      ACTs as first line treatment for malaria
      Public- Private partnership (to address demand and
       supply side of anti-malarial drugs
      use of research evidence to address diseases of
       poverty
   Difficult to achieve MDGs without addressing
    poor peoples’ access to quality anti-malarial
    services through evidence-based innovations.
                            10
FHS Nigeria:-Purpose and Objectives
Goal
       To improve PMVs’ provision of quality malaria
        services to poor people through innovative
        public and private sector engagement, citizen
        empowerment, surveillance and sustainable
        malaria drug regulation policies.
Specific objectives
    Generate knowledge that would aid the
        understanding of issues and perceptions
        related to poverty and malaria vulnerability.
       Develop intervention proposals that will test or
        guide changes in the health systems that could
        have a major impact on the poor



                Oladepo_ Strengthening Malaria Control
                 Interventions through PMVs- Nigeria     11
FHS Nigeria :Project Phases
 How can the poor get access to effective malaria treatment?

                          Inception Phase




                             FHS            Phase II
                Phase I




                                                               12
FHS Nigeria :Inception Phase
 How can the poor get access to effective malaria treatment?




                Inception Phase
                  Oct 2005-Mar2006.

              Engaged stakeholders
              to define research
              agenda through
              bilateral consultation
              (NAP, PMV associations,
              MOH, DFID)




                                                               13
FHS Nigeria :Project Phase I
 How can the poor get access to effective malaria treatment?




                   Phase I
                   Apr 06-Dec 07
            Formative research
            Intervention design
            Research to policy




                                                               14
Oladepo_ Strengthening Malaria Control
 Interventions through PMVs- Nigeria     15
Formative Research-Results
     First Source of Treatment for Most Recent Episode of Malaria
                   100%




                   80%


                                                  Government health facility
Percent of Cases




                   60%                            Private health facility

                                                  Self-treatment traditional
                                                  medicine
                                                  Self-treatment with modern
                   40%                            medicine
                                                  Patent Medicine Vendor



                   20%




                    0%
                          Oyo    Kaduna   Enugu

                                                                            16
54 Different Types of Anti-malarial Drugs
Found in Oyo, Enugu & Kaduna




                                            17
Percent of Patent Medical Vendor
                   Shops with Anti-Malarial Drugs
                   100

                   90

                   80

                   70
Percent of Shops




                   60

                   50

                   40

                   30

                   20

                   10

                    0
                         ACTs   Monotherapy         Chloroquine            Sulfadoxine-   Other
                                artusenates                               pyrimethamine
                                 Oladepo_ Strengthening Malaria Control
                                  Interventions through PMVs- Nigeria                             18
Mean Price of Malaria Brands

        600
              504
        500
                            393
        400
Naira




        300                                                       272

        200
                                                 83          91
        100

         0
              ACT      AS-Mono                   CQ          SP   Other



                    Oladepo_ Strengthening Malaria Control
                     Interventions through PMVs- Nigeria                  19
Other Study Findings
 PMVs know little about malaria policy
  change
 Low quality drugs cited as major problem
   HH leaders, PMVs associations & Policy makers &
   Public facility health workers)
 Most express low confidence in
  government to regulate (wide regional variation)
 Gov’t officials know very little about PMV
  Associations
 DISSEMINATED FINDINGS TO POLICY MAKERS &
  OTHER STAKEHOLDERS

               Oladepo_ Strengthening Malaria Control
                Interventions through PMVs- Nigeria     20
What are the Options?

   Business as usual
   Educate parents, PMVs
   Subsidize all ACTs
   Support low-cost diagnostics
   Support local institutions that work:
    civil society, PMV associations, gov’t
    regulators, industry, to monitor
    treatment/quality of drugs

                Oladepo_ Strengthening Malaria
              Control Interventions through PMVs-
                             Nigeria                21
FHS Nigeria :Project Phase II
 How can the poor get access to effective malaria treatment?




                                  Phase II
                                 Jan08- June 2009




                          Intervention design

                           Evidence to policy




                                                               22
Proposed Interventions
 Quality Drug Testing with Mini-Lab Equipment by
  PMVs (                           )

 Performance improvement
      Training-Increasing PMV knowledge through competency
        based Training (
                  )
      Use of Cell phones-Messaging and information sharing on
        drugs, policy, regulations, guidelines between government
        health workers and PMVs (                             )

   Co-regulation with PMV Associations, citizens groups,
    government


   Increasing consumer knowledge and engagement
    for monitoring drug quality

                  Oladepo_ Strengthening Malaria Control
                   Interventions through PMVs- Nigeria         23
Stakeholders meetings



 Series of stakeholders’ meetings organized
  by FHS with Stakeholders led to sharing
  and refining scope of proposed
  interventions




              Oladepo_ Strengthening Malaria
            Control Interventions through PMVs-
                           Nigeria                24
 FHS :The Abuja Meeting-Jan.2009
  Theme:“Making health markets work for the
  Poor”
    Policy makers, potential collaborators, civil society,
     representatives of private sector partners, the media
     and innovators from organized private sector and
     Consortium research partners from over the world
     came together to learn, gather resources and plan for
     implementation




                                                       25
26
 The Speaker of the House of Representatives, the Right
  Honourable Dimeji S Bankole, stated thus about the
  Abuja workshop:
“Current indicators point to the fact that we are seriously lagging behind,
    particularly on the MDGs health components of maternal and child
    health… I truly appreciate the overall goal of this workshop which is
    meant to share experiences on innovative health interventions that
    benefit the poor and under-privileged segments of our population...I
    consider this discourse of utmost relevance in the overall strive to
    deliver affordable, accessible, qualitative and all-encompassing
    healthcare through a complementary multi-stakeholder
    partnership...Initiatives such as conceptualised by this workshop are
    important to us in the House of Representatives...”

   Abuja workshop Outcome- High-level policy makers indicated strong
    support for formal integrating of PMVs into National malaria control
    interventions


                                                                         27
FHS Nigeria :Project Phase III
 How can the poor get access to effective malaria treatment?




                                 Phase III
                              July 09- September 2010


                           Evidence to policy




                                                               28
 Follow –up stakeholders consensus meetings
    National stakeholders meeting for integrated and
     unified approach to PMV work through NMCP
     facilitated by FHS

Outcome
    Two interventions approved (PMV Institutionalized
     Training and PMV Regulatory framework)
    PMV curriculum and regulatory framework documents
     developed and approved by National Malaria Control
     Program (NMCP) for implementation at the state level
    National Malaria Control Program adopted the use
     of PMV for treatment of uncomplicated malaria in
     Nigeria
                 Oladepo_ Strengthening Malaria
               Control Interventions through PMVs-
                              Nigeria                 29
30
World Bank (WB) Additional Financing
 support for PMV Work-Nigeria
 Stimulated by the FHS generated evidence
  which informed FMOH NMCP decision making
  on PMV involvement in malaria control, NMCP
  is targeting World Bank additional financing to
  strengthen private sector delivery of key
  malaria control interventions through PMVs
 Goal is to effective scale up, increased and
  sustained malaria coverage with existing
  control tools
 A hybrid PMV Malaria Intervention model to drive
  implementation has been developed
                 Oladepo_ Strengthening Malaria
               Control Interventions through PMVs-
                              Nigeria                31
 Tools have been developed for implementation
  of components of the model in Booster States (7
  states {Green Colour in theMap below)
 State level start-up activities with PMVs have
  commenced




                                  Oladepo _Involvement of PMVs in
32                                                 Malaria control
Conclusion from FHS Nigeria PMV
   Study
 New policy knowledge created,which enables a
  more systematic process of learning
 Generated evidence better informs decision-
  making about private sector involvement in
  malaria interventions through PMVs
 Creation of national and international interest
  and support for PMV work in Nigeria (e.g. World
  Bank’s Additional Financial support for PMV
  work)
 Capability to do and use research strengthened
 PMV associations being strengthened
      PMV capacity to deliver quality services (ACTs,
       Counseling and Referrals) consistent with
       government guidelines and best malaria
       treatment practices.

 Finally, research funded by DFiD has helped
  shaped national health policy/program in
  favour of PMV integration into Malaria Control
  program in Nigeria




                    Oladepo _ Involvement of PMVs in Malaria control

                                        34

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Beyond Scaling Up: Working with patent medicine vendors in Nigeria

  • 1. Strengthening the Delivery of Key Malaria Control Interventions through Patent Medicine Vendors in Nigeria Oladimeji Oladepo Country Coordinator Future Health Systems (Nigeria) University of Ibadan Beyond Scaling Up-May 24-26, 2010 Oladepo_ Strengthening Malaria Control Interventions through PMVs- Nigeria 1
  • 2. Oladepo _ Involvement of PMVs in Malaria control 2
  • 3. The Central Question Why involve PMVs in malaria control services ? Oladepo _Involvement of PMVs in Malaria control 3
  • 4.  Very high Malaria burden  Nigeria contributes ~25% of the total African malaria morbidity and mortality burden Estimated 57.5 million cases and 225,000 deaths (25% of global malaria burden; WHO 2008) 11% of maternal and 29% of under five death is due to malaria Malaria is intricately linked with poverty (significant drain on the economy and wellbeing) Oladepo _ Involvement of PMVs in Malaria control 4
  • 5. Fig 1: Major Communicable Diseases in Nigeria , 2005 (Source Erinoso, 2010) Oladepo _Involvement of PMVs in Malaria 5 control
  • 6.  Low coverage of ACTs, first-line drug  ACTs most effective form of Medicine for treating malaria, yet …… access through Public Sector is highly limited Quantity stocked or sold by PMVs is very low  8.5% of PMVs stocked ACTs compared to 32.1 for monotherapy and 71.7 for Chloroquine (Oladepo et al,2007)  Overall ACT access in Nigeria remains critically low with a projected gap of 80 % stretching through 2011(AMFM,2010) Oladepo _ Involvement of PMVs in Malaria control 6
  • 7. Projected gap in ACTs till 2011(Source AMFM, 2010) Children <5 Receiving 2008 ACT Need and Gap an ACT Within 24hrs MN % 90% 100 89.5 6 80% 11.5 70% 71.9 60% 50% 50 40% ~80% of need not 30% covered 20% 10% 0% 0 2007 2008 2011 Total ACT Dist. in Gap MICS 18 GF Target Dist. in Need to public States private Cover Pop. sector Oladepo_ Involvement of PMVs in Malaria sector control 7O
  • 8.  Untapped capacity of PMVs in Anti- malarial Medicine provision  PMVs remain the first point of call seeking treatment for fevers in Nigeria (Salako, Brieger, Afolabi, Umeh, & Agomo, 2001)  High level of patronage (up to 70%)  Used even when supposedly more convenient and cheaper alternatives exist (e.g PHC centres,Village health workers)(Brieger, Salako, Umeh, Agomo, Afolabi & Adeneye, 2002-3; Kaseje, Spencer& Sempebwa, 1987)  The most common item stocked by PMVs is anti- malarias (ACTWATCH,2010) Oladepo _ Involvement of PMVs in Malaria control 8
  • 9. Proportion of the total volume of all anti-malarials sold or distributed in the 1 week preceding the ACTwatch survey (Source ACTWATCH, 2010) Oladepo _Involvement of PMVs in 9 Malaria control
  • 10.  Despite existence of supportive policy documents, access of poor people to quality anti- malarial services remains low  government approved policies  Investment in pro-poor programs targeting malaria(NEEDS)  ACTs as first line treatment for malaria  Public- Private partnership (to address demand and supply side of anti-malarial drugs  use of research evidence to address diseases of poverty  Difficult to achieve MDGs without addressing poor peoples’ access to quality anti-malarial services through evidence-based innovations. 10
  • 11. FHS Nigeria:-Purpose and Objectives Goal  To improve PMVs’ provision of quality malaria services to poor people through innovative public and private sector engagement, citizen empowerment, surveillance and sustainable malaria drug regulation policies. Specific objectives  Generate knowledge that would aid the understanding of issues and perceptions related to poverty and malaria vulnerability.  Develop intervention proposals that will test or guide changes in the health systems that could have a major impact on the poor Oladepo_ Strengthening Malaria Control Interventions through PMVs- Nigeria 11
  • 12. FHS Nigeria :Project Phases How can the poor get access to effective malaria treatment? Inception Phase FHS Phase II Phase I 12
  • 13. FHS Nigeria :Inception Phase How can the poor get access to effective malaria treatment? Inception Phase Oct 2005-Mar2006. Engaged stakeholders to define research agenda through bilateral consultation (NAP, PMV associations, MOH, DFID) 13
  • 14. FHS Nigeria :Project Phase I How can the poor get access to effective malaria treatment? Phase I Apr 06-Dec 07 Formative research Intervention design Research to policy 14
  • 15. Oladepo_ Strengthening Malaria Control Interventions through PMVs- Nigeria 15
  • 16. Formative Research-Results First Source of Treatment for Most Recent Episode of Malaria 100% 80% Government health facility Percent of Cases 60% Private health facility Self-treatment traditional medicine Self-treatment with modern 40% medicine Patent Medicine Vendor 20% 0% Oyo Kaduna Enugu 16
  • 17. 54 Different Types of Anti-malarial Drugs Found in Oyo, Enugu & Kaduna 17
  • 18. Percent of Patent Medical Vendor Shops with Anti-Malarial Drugs 100 90 80 70 Percent of Shops 60 50 40 30 20 10 0 ACTs Monotherapy Chloroquine Sulfadoxine- Other artusenates pyrimethamine Oladepo_ Strengthening Malaria Control Interventions through PMVs- Nigeria 18
  • 19. Mean Price of Malaria Brands 600 504 500 393 400 Naira 300 272 200 83 91 100 0 ACT AS-Mono CQ SP Other Oladepo_ Strengthening Malaria Control Interventions through PMVs- Nigeria 19
  • 20. Other Study Findings  PMVs know little about malaria policy change  Low quality drugs cited as major problem HH leaders, PMVs associations & Policy makers & Public facility health workers)  Most express low confidence in government to regulate (wide regional variation)  Gov’t officials know very little about PMV Associations  DISSEMINATED FINDINGS TO POLICY MAKERS & OTHER STAKEHOLDERS Oladepo_ Strengthening Malaria Control Interventions through PMVs- Nigeria 20
  • 21. What are the Options?  Business as usual  Educate parents, PMVs  Subsidize all ACTs  Support low-cost diagnostics  Support local institutions that work: civil society, PMV associations, gov’t regulators, industry, to monitor treatment/quality of drugs Oladepo_ Strengthening Malaria Control Interventions through PMVs- Nigeria 21
  • 22. FHS Nigeria :Project Phase II How can the poor get access to effective malaria treatment? Phase II Jan08- June 2009 Intervention design  Evidence to policy 22
  • 23. Proposed Interventions  Quality Drug Testing with Mini-Lab Equipment by PMVs ( )  Performance improvement  Training-Increasing PMV knowledge through competency based Training ( )  Use of Cell phones-Messaging and information sharing on drugs, policy, regulations, guidelines between government health workers and PMVs ( )  Co-regulation with PMV Associations, citizens groups, government  Increasing consumer knowledge and engagement for monitoring drug quality Oladepo_ Strengthening Malaria Control Interventions through PMVs- Nigeria 23
  • 24. Stakeholders meetings  Series of stakeholders’ meetings organized by FHS with Stakeholders led to sharing and refining scope of proposed interventions Oladepo_ Strengthening Malaria Control Interventions through PMVs- Nigeria 24
  • 25.  FHS :The Abuja Meeting-Jan.2009 Theme:“Making health markets work for the Poor”  Policy makers, potential collaborators, civil society, representatives of private sector partners, the media and innovators from organized private sector and Consortium research partners from over the world came together to learn, gather resources and plan for implementation 25
  • 26. 26
  • 27.  The Speaker of the House of Representatives, the Right Honourable Dimeji S Bankole, stated thus about the Abuja workshop: “Current indicators point to the fact that we are seriously lagging behind, particularly on the MDGs health components of maternal and child health… I truly appreciate the overall goal of this workshop which is meant to share experiences on innovative health interventions that benefit the poor and under-privileged segments of our population...I consider this discourse of utmost relevance in the overall strive to deliver affordable, accessible, qualitative and all-encompassing healthcare through a complementary multi-stakeholder partnership...Initiatives such as conceptualised by this workshop are important to us in the House of Representatives...”  Abuja workshop Outcome- High-level policy makers indicated strong support for formal integrating of PMVs into National malaria control interventions 27
  • 28. FHS Nigeria :Project Phase III How can the poor get access to effective malaria treatment? Phase III July 09- September 2010  Evidence to policy 28
  • 29.  Follow –up stakeholders consensus meetings  National stakeholders meeting for integrated and unified approach to PMV work through NMCP facilitated by FHS Outcome  Two interventions approved (PMV Institutionalized Training and PMV Regulatory framework)  PMV curriculum and regulatory framework documents developed and approved by National Malaria Control Program (NMCP) for implementation at the state level  National Malaria Control Program adopted the use of PMV for treatment of uncomplicated malaria in Nigeria Oladepo_ Strengthening Malaria Control Interventions through PMVs- Nigeria 29
  • 30. 30
  • 31. World Bank (WB) Additional Financing support for PMV Work-Nigeria  Stimulated by the FHS generated evidence which informed FMOH NMCP decision making on PMV involvement in malaria control, NMCP is targeting World Bank additional financing to strengthen private sector delivery of key malaria control interventions through PMVs  Goal is to effective scale up, increased and sustained malaria coverage with existing control tools  A hybrid PMV Malaria Intervention model to drive implementation has been developed Oladepo_ Strengthening Malaria Control Interventions through PMVs- Nigeria 31
  • 32.  Tools have been developed for implementation of components of the model in Booster States (7 states {Green Colour in theMap below)  State level start-up activities with PMVs have commenced Oladepo _Involvement of PMVs in 32 Malaria control
  • 33. Conclusion from FHS Nigeria PMV Study  New policy knowledge created,which enables a more systematic process of learning  Generated evidence better informs decision- making about private sector involvement in malaria interventions through PMVs  Creation of national and international interest and support for PMV work in Nigeria (e.g. World Bank’s Additional Financial support for PMV work)  Capability to do and use research strengthened
  • 34.  PMV associations being strengthened PMV capacity to deliver quality services (ACTs, Counseling and Referrals) consistent with government guidelines and best malaria treatment practices.  Finally, research funded by DFiD has helped shaped national health policy/program in favour of PMV integration into Malaria Control program in Nigeria Oladepo _ Involvement of PMVs in Malaria control 34