American Medical Informatics Association (AMIA) Spring Congress, Walt Disney World Swan, May 28th–30th, 2009, Orlando, Florida, USA

1. EVOLVE: INTEGRATED GLOBAL EARLY WARNING AND RESPONSE SYSTEM Innovative Support to Emergencies, Diseases, and Disasters Photo credit: IRMA (Integrated Risk Management for Africa) AMIA Spring Congress Walt Disney World Swan May 28 th –30 th , 2009, Orlando, Florida, USA Taha Kass-Hout, MD, MS Director, Global Public Health and Informatics

3. Late Detection – Response DAY CASES Opportunity for control

4. Early Detection and Response DAY CASES Opportunity for control

8. Making Mobile Tech Work for Health Avian Influenza Exercise: Stung Treng Province, Cambodia, October 13-15, 2008 SE Asia Region (Source: Wikipedia) The Komphun rural Health Center serves over 7000 population in the Stung Treng and neighboring provinces. Cell phone use during the Avian Influenza Exercise: Stung Treng Province, Cambodia, October 13-15, 2008

9. Growth of Mobile Technologies Adapted from Dzenowagi, WHO, 2005

11. Urban – Rural Population, SE Asia UNCTAD Handbook of Statistics 2004 Adapted from Dzenowagi, WHO, 2005 Year: 2002

14. Evolve Architecture and Processes Best Poster Award for Improving Public Health Investigation and Response at the Seventh Annual ISDS Conference, 2008 http://kasshout.blogspot.com/2008/12/best-poster-award-for-improving-public.html

15. Evolve Architecture and Processes Feature extraction, reference and baseline information Tags Multiple Data Streams User-Generated and Machine Learning Metadata Comments Spatio-temporal Flags/Alerts/Bookmarks Evolve Bot Event Classification, Characterization and Detection Previous Event Training Data Previous Event Control Data Metadata extraction Machine learning Social network Professional feedback Anomaly detection Collaborative Spaces Hypotheses generationesting

16. Evolve Related items (e.g., News articles) are grouped into a thread. Threads are later associated with events (hypothesized or confirmed). Collaborative-centric semantic tags Expert-generated semantic tags Publish and Share Information Create a filter (by keyword, tag, topic, location, or time) and subscription (email, GeoRSS, SMS Text Messaging, Twitter, etc.) An event is monitored through a thread of items Data source: SE Asia Evolve Collaborative Workspace http://riff.instedd.org/space/ProMed-MBDS List view Yin Myo Aye, MD: ProMED MBDS Taha Kass-Hout, MD, MS: InSTEDD

17. Evolve Expert-centric auto-generated (machine-learning) semantic tags and related items Data source: SE Asia Evolve Collaborative Workspace http://riff.instedd.org/space/ProMed-MBDS Tags are semantically ranked (a statistical possibility match). Users can further train the classifier by rejecting a suggestion. Users can also train the geo-locator by rejecting or updating a location . Yin Myo Aye, MD: ProMED MBDS Taha Kass-Hout, MD, MS: InSTEDD

18. Evolve Map view Data source: SE Asia Evolve Collaborative Workspace http://riff.instedd.org/space/ProMed-MBDS Semantic map to monitor topic rise or decay over time Yin Myo Aye, MD: ProMED MBDS Taha Kass-Hout, MD, MS: InSTEDD

19. Evolve Filter feature which automatically filters content by topic of interest Filter content by radius Data source: SE Asia Evolve Collaborative Workspace http://riff.instedd.org/space/ProMed-MBDS Yin Myo Aye, MD: ProMED MBDS Taha Kass-Hout, MD, MS: InSTEDD

24. Influenza A(H1N1), 2009 Data source: Google Insights for Search http://www.google.com/insights/search/#q=%22swine%20flu%22%2C%22avian%20flu%22&cmpt=q avian flu swine flu

25. Influenza A(H1N1), 2009 Data source: HashTags.org monitoring Twitter http://hashtags.org/tag/swineflu/messages

26. Influenza A(H1N1), 2009 Data source: A(H1N1) Evolve Collaborative Workspace http://riff.instedd.org/space/SwineFlu Yin Myo Aye, MD: ProMED MBDS Taha Kass-Hout, MD, MS: InSTEDD

27. Influenza A(H1N1), 2009 Data source: A(H1N1) Evolve Collaborative Workspace http://riff.instedd.org/space/SwineFlu Yin Myo Aye, MD: ProMED MBDS Taha Kass-Hout, MD, MS: InSTEDD Mid-March 2009 thru May 19 th 2009

28. Influenza A(H1N1), 2009 Data source: A(H1N1) Evolve Collaborative Workspace http://riff.instedd.org/space/SwineFlu Mid-March 2009 thru May 19 th 2009 Yin Myo Aye, MD: ProMED MBDS Taha Kass-Hout, MD, MS: InSTEDD

29. Influenza A(H1N1), 2009 Data source: A(H1N1) Evolve Collaborative Workspace http://riff.instedd.org/space/SwineFlu Mid-March 2009 thru May 19 th 2009 Yin Myo Aye, MD: ProMED MBDS Taha Kass-Hout, MD, MS: InSTEDD

30. Avian Influenza: Egypt, 2009 Tracking the recent Avian Influenza Outbreak in Egypt (reports started to appear late January 2009). Data source: Africa Evolve Collaborative Workspace http://riff.instedd.org/space/AfricaAlerts

31. Worldwide Health Events, 2008 Data source: Early Detection and Response Evolve Collaborative Workspace http://riff.instedd.org/space/DEMOEventDetection

32. Acknowledgment

33. Through Funding from…

34. Thank You! In STEDD 400 Hamilton Avenue, Suite 120 Palo Alto, CA 94301, USA +1.650.353.4440 +1.877.650.4440 (toll-free in the US) [email_address] Cambodia, Photo taken by Taha Kass-Hout, October 2008 “ this pic says it all- our kids are all the same- they deserve the same ”, Comment by Robert Gregg on Facebook, October 2008