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Who’s Up for a Swim
  @ the BEACH?
    By Kane Guthrie
The Lucky Country
Australia home to:
• 38 terrestrial snakes
• 23 sea snakes
• 22 spiders
• 7 jellyfish
• 2 blue ringed octopuses,
• 2 stone fish
• Plus many more venomous creatures.
Marine Envenomation
• Australian waters contain great variety of
  venomous sea creatures.
• Includes jellyfish, sea snakes, blue-ringed
  octopus, stonefish,& stingrays.
• Jellyfish stings most common marine medical
  emergency.
• It’s estimated 10 000 jellyfish stings occur
  each year.
The Approach




         http://www.marine-medic.com.au/
Sea Snakes
• Found in most waters around Aust.
• Venom contains neuro toxins (paralysis) and
  Myotoxins (rhabdomyolysis).
• Close resemblance to land snakes.
• Inquisitive, but rarely aggressive.
• Bites normally occur during handling.

• Fatalities & Paralysis rare!!
Clinical Presentation
Localised:
• Bite- small, superficial, relatively painless,
  generally no local swelling.
Systemic:
• Non specific – headache, nausea & vomiting.
• Symmetrical descending flaccid paralysis
  manifest within 6 hours.
• Rhabdo develops leading to ARF.
Emergency Department
             Management
Pre-Hospital:
• PIB
In ED:
• Check CK- give fluids
• Paralysis can lead to Resp failure
• Prepare to secure the airway
• CSL Sea Snake Antivenom or Tiger Snake
   (Reverses paralysis)
• Observe for 12 hours, Don’t D/C @ night.
Bluebottle Jellyfish
• Responsible for thousand of stings each year!
• Causes intense local pain and dermal
  erythema.
Clinical Presentation
Localised:
• Immediate burning pain – lasting up 2 hours.
• Erythematous welts.
Systemic:
• Non specific symptoms include – nausea,
  headache or malaise.
Emergency Department
             Management
Pre-Hospital:
• Hot shower for 20mins (45°C optimal
  temperature).
• Reassurance.
In ED:
• Provide hot shower if not already done.
• Simple analgesia.
• D/C when symptoms improving.
Box Jellyfish

• Found in tropical Australian waters.
• Most stings are benign, respond well to
  supportive management.
• Severe envenoming has been associated with
  70 deaths in Aust.
• Deaths occur through venoms direct cardiac
  toxicity.
Clinical Presentation
Localised:
• Immediate severe pain, lasting up to 8 hours.
• Linear welts in cross hatched pattern.
• In 25-30% cases tentacles still adherent.
Systemic:
• Within minutes collapse and cardiac arrest can occur.
• HT, tachycardia, hypotension, impaired cardiac
  conduction and arrhythmias.
Ongoing:
• Delayed hypersensitivity pruritic erythema rash can
  occur 7-14 days after sting.
Emergency Department
              Management
Pre-hospital:
• Apply vinegar to deactivate nematocyst.
In ED:
Minor:
• Apply vinegar, ICE packs, analgesia.
Severe:
• Cardiac monitor, analgesia-opiate, fluid boluses.
• CSL Box Jellyfish antivenom (3 ampoules)
• Cardiac arrest – 6 ampoules of antivenom, if
   refractory try Mg.
Irukandji Syndrome
• Poorly understood condition!
• Characterized by:
 Severe pain
 Sympathomimetic state
 Potential for life threatening cardiovascular
  complications.
• Caused by Jellyfish envenomation –
  Carukiabarnesiis one specie of jellyfish that cause
  it, many other jellyfish are postulated as causing
  it.
Locations of Attacks

• Found in tropical waters.
• Fatalities have been reported r/t ICH.
• We have had Pt’s T/F to SCGH ED for ongoing
  management.
Clinical Presentation
Localised:
• Initial sting generally not felt – leads to short period
  before systemic symptoms.
Systemic:
• Multiple systemic effects occur 30-90 minutes –
  agitation, dsyphoria, vomiting, diaphoresis, severe pain
  back, limbs, abdomen.
• HT and tachycardia common.
Rare:
• Life threatening HT & APO may develop leading to
  cardiovascular collapse.
Emergency Department
              Management
Pre-hospital:
• Generous application of vinegar to all sting sites
   (deactivates nematocyst).
In ED:
• Manage initially in resus – full monitoring!
• Provide analgesia – may need PCA.
• Treat nausea & control HT.
• Mg may treat refractory pain.
• Severe envenoming develops within 4/24
   subsides by 12 hours.
Blue-ringed Octopus
• Found in shallow coastal waters
• Envenoming causes rapid paralysis.
• When handled or enraged it changes colour –
  develops blue rings.
• Maculotoxin –leads to sodium channel
  blockade causes neuro-toxicity resulting in
  paralysis.
Clinical Presentation
Localised:
• The bite may not be painful.
• Local symptoms are minimal or absent.
Systemic:
• Characterised by rapidly progressive
  descending paralysis.
• Early signs- blurred vision, diplopia, ptosis,
  difficulty swallowing.
Emergency Department
              Management
Pre-hospital:
• Apply PIB, assisted ventilation.
In ED:
• Monitored in resus bay – watch for paralysis, resp
   failure and hypotension.
• Resp failure occurs- secure airway provide
   mechanical ventilation.
• Paralysis resolves with 24 hours.
• No antidote available.
Stonefish
• Extremely well camouflaged reef fish.
• Found in shallow waters around rocks & coral
  reefs.
• Found in northern Australian waters!
• Their dorsal spines contain venom.
Clinical Presentation
Localised:
• Pain @ site. (Usually severe)
• Swelling, bruising & puncture marks.
Systemic:
• Non-specific signs: nausea, vomiting, dyspnoea &
  dizziness.
Rare:
• Hypotension, bradycardia, collapse, APO- have
  been rarely reported. No deaths in Aust.
Emergency Department
             Management
Pre-hospital:
• Analgesia, immerse limb in hot water 45°C
In ED:
• IV opioid analgesia – continue hot water
• Wound management – debridement, ADT, AB’s
• X-ray detect FB
• Antivenom – neutralizes some components of
   venom. (unproven – generally not required).
Questions
Take Home Points
• Marine envenomation is common depending
  on were you work.
• PIB on for BRO & sea snake bite.
• Antivenom’s have a limited role & risks.
• Supportive care is paramount!
• Avoid D/C @ night!
Thank-You

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Marine Envenomation

  • 1. Who’s Up for a Swim @ the BEACH? By Kane Guthrie
  • 2. The Lucky Country Australia home to: • 38 terrestrial snakes • 23 sea snakes • 22 spiders • 7 jellyfish • 2 blue ringed octopuses, • 2 stone fish • Plus many more venomous creatures.
  • 3. Marine Envenomation • Australian waters contain great variety of venomous sea creatures. • Includes jellyfish, sea snakes, blue-ringed octopus, stonefish,& stingrays. • Jellyfish stings most common marine medical emergency. • It’s estimated 10 000 jellyfish stings occur each year.
  • 4. The Approach http://www.marine-medic.com.au/
  • 5. Sea Snakes • Found in most waters around Aust. • Venom contains neuro toxins (paralysis) and Myotoxins (rhabdomyolysis). • Close resemblance to land snakes. • Inquisitive, but rarely aggressive. • Bites normally occur during handling. • Fatalities & Paralysis rare!!
  • 6. Clinical Presentation Localised: • Bite- small, superficial, relatively painless, generally no local swelling. Systemic: • Non specific – headache, nausea & vomiting. • Symmetrical descending flaccid paralysis manifest within 6 hours. • Rhabdo develops leading to ARF.
  • 7. Emergency Department Management Pre-Hospital: • PIB In ED: • Check CK- give fluids • Paralysis can lead to Resp failure • Prepare to secure the airway • CSL Sea Snake Antivenom or Tiger Snake (Reverses paralysis) • Observe for 12 hours, Don’t D/C @ night.
  • 8. Bluebottle Jellyfish • Responsible for thousand of stings each year! • Causes intense local pain and dermal erythema.
  • 9. Clinical Presentation Localised: • Immediate burning pain – lasting up 2 hours. • Erythematous welts. Systemic: • Non specific symptoms include – nausea, headache or malaise.
  • 10. Emergency Department Management Pre-Hospital: • Hot shower for 20mins (45°C optimal temperature). • Reassurance. In ED: • Provide hot shower if not already done. • Simple analgesia. • D/C when symptoms improving.
  • 11. Box Jellyfish • Found in tropical Australian waters. • Most stings are benign, respond well to supportive management. • Severe envenoming has been associated with 70 deaths in Aust. • Deaths occur through venoms direct cardiac toxicity.
  • 12. Clinical Presentation Localised: • Immediate severe pain, lasting up to 8 hours. • Linear welts in cross hatched pattern. • In 25-30% cases tentacles still adherent. Systemic: • Within minutes collapse and cardiac arrest can occur. • HT, tachycardia, hypotension, impaired cardiac conduction and arrhythmias. Ongoing: • Delayed hypersensitivity pruritic erythema rash can occur 7-14 days after sting.
  • 13.
  • 14. Emergency Department Management Pre-hospital: • Apply vinegar to deactivate nematocyst. In ED: Minor: • Apply vinegar, ICE packs, analgesia. Severe: • Cardiac monitor, analgesia-opiate, fluid boluses. • CSL Box Jellyfish antivenom (3 ampoules) • Cardiac arrest – 6 ampoules of antivenom, if refractory try Mg.
  • 15. Irukandji Syndrome • Poorly understood condition! • Characterized by:  Severe pain  Sympathomimetic state  Potential for life threatening cardiovascular complications. • Caused by Jellyfish envenomation – Carukiabarnesiis one specie of jellyfish that cause it, many other jellyfish are postulated as causing it.
  • 16. Locations of Attacks • Found in tropical waters. • Fatalities have been reported r/t ICH. • We have had Pt’s T/F to SCGH ED for ongoing management.
  • 17. Clinical Presentation Localised: • Initial sting generally not felt – leads to short period before systemic symptoms. Systemic: • Multiple systemic effects occur 30-90 minutes – agitation, dsyphoria, vomiting, diaphoresis, severe pain back, limbs, abdomen. • HT and tachycardia common. Rare: • Life threatening HT & APO may develop leading to cardiovascular collapse.
  • 18. Emergency Department Management Pre-hospital: • Generous application of vinegar to all sting sites (deactivates nematocyst). In ED: • Manage initially in resus – full monitoring! • Provide analgesia – may need PCA. • Treat nausea & control HT. • Mg may treat refractory pain. • Severe envenoming develops within 4/24 subsides by 12 hours.
  • 19. Blue-ringed Octopus • Found in shallow coastal waters • Envenoming causes rapid paralysis. • When handled or enraged it changes colour – develops blue rings. • Maculotoxin –leads to sodium channel blockade causes neuro-toxicity resulting in paralysis.
  • 20. Clinical Presentation Localised: • The bite may not be painful. • Local symptoms are minimal or absent. Systemic: • Characterised by rapidly progressive descending paralysis. • Early signs- blurred vision, diplopia, ptosis, difficulty swallowing.
  • 21. Emergency Department Management Pre-hospital: • Apply PIB, assisted ventilation. In ED: • Monitored in resus bay – watch for paralysis, resp failure and hypotension. • Resp failure occurs- secure airway provide mechanical ventilation. • Paralysis resolves with 24 hours. • No antidote available.
  • 22. Stonefish • Extremely well camouflaged reef fish. • Found in shallow waters around rocks & coral reefs. • Found in northern Australian waters! • Their dorsal spines contain venom.
  • 23. Clinical Presentation Localised: • Pain @ site. (Usually severe) • Swelling, bruising & puncture marks. Systemic: • Non-specific signs: nausea, vomiting, dyspnoea & dizziness. Rare: • Hypotension, bradycardia, collapse, APO- have been rarely reported. No deaths in Aust.
  • 24. Emergency Department Management Pre-hospital: • Analgesia, immerse limb in hot water 45°C In ED: • IV opioid analgesia – continue hot water • Wound management – debridement, ADT, AB’s • X-ray detect FB • Antivenom – neutralizes some components of venom. (unproven – generally not required).
  • 26. Take Home Points • Marine envenomation is common depending on were you work. • PIB on for BRO & sea snake bite. • Antivenom’s have a limited role & risks. • Supportive care is paramount! • Avoid D/C @ night!