Cl Perf+ Cl Botu

Clostridium perfringens Clostridium botulinum Dr Kamran Afzal Classified Microbiologist

Clinically important Gram positive bacilli ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Spores ,[object Object],[object Object],[object Object],[object Object],[object Object]

Classification Based On The Type Of Disease Produced ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Introductory Characteristics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Clostridium Associated Human Diseases

Characteristics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Epidemiology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Virulence Factors Major Minor ,[object Object],[object Object]

Lab Diagnosis ,[object Object],Inner beta-hemolysis = θ toxin Outer alpha-hemolysis = α toxin ,[object Object],[object Object]

[object Object],NOTE: Lecithinase ( α -toxin; phospholipase) hydrolyzes phospholipids in egg-yolk agar around streak on right. Antibody against α -toxin inhibits activity around left streak Cl perfringens Cl histolyticum Cl septicum Cl novyii

Clostridial food poisoning ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object]

Necrotizing enteritis (Pig-bel) ,[object Object],[object Object],[object Object],[object Object]

Pathogenesis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Management ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Epidemiology ,[object Object],[object Object],[object Object],[object Object]

Characteristics ,[object Object],[object Object],[object Object],[object Object],[object Object]

Action of Toxin ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Mechanism of Action of Toxin ,[object Object],[object Object],[object Object],[object Object]

Symptoms ,[object Object],[object Object],[object Object],[object Object],[object Object]

Clinical Syndromes ,[object Object],[object Object],[object Object],[object Object],[object Object]

Lab diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object]

Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Alternative botulism uses ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object]

Cl Perf+ Cl Botu

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Cl Perf+ Cl Botu