1. Comparative Cost Effectiveness Modeling: Demonstrating a Product’s Value Proposition 3 rd Annual Health Outcomes and Pharmacoeconomics Research Josh Feldstein President and CEO © Copyright 2012 Center for Applied Value Analysis, Inc (CAVA). All rights reserved.

3. Value Analytics and CCE: A Brief Overview… 02/29/12

7. CCE’s Impact at Hospitals and Among Payers… 02/29/12

8. And With Industry… 02/29/12

9. Key Definitions

12. Key CCE Value Analytics Challenges 02/29/12

13. CCE Modeling Needs Today

15. Value Analytic CCE Models

18. Example of an Online CCE Model Drug Input Dashboard 02/29/12

19. Sample Online Adverse Event Dashboard 02/29/12

20. Example of an Online CCE Model Device Output Dashboard 02/29/12

21. Sample Online CCE Model Pharmaceutical Output Example 02/29/12

23. Value Analytics Program Design 02/29/12 Model Structure Design CCE Data Collection and Integration Model Launch Ongoing Enhancements Model 2.0+ Planning and Due Diligence Ongoing CCE ManagementEducation

25. Comparative Cost Effectiveness Modeling: How to Demonstrate a Product’s Value Proposition 3 rd Annual Health Outcomes and Pharmacoeconomics Research Josh Feldstein President and CEO