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By:
                 Jitendra Bhangale
                     M.Pharm. DIPL




By the end of the lesson you should be able to
 Describe the transmission of impulses from senses
  to central nervous system and back to muscles.
 Describe the reflex action and the pathway of the
  reflex arc.
 Describe the function of reflex response.
 Describe the role of the central nervous system.




                                                      1
nervous system




                 2
sensory   relay     motor
neurone   neurone   neurone




                              3
Carries impulses from receptors e.g pain
receptors in skin to the CNS( brain or spinal
cord)




Carries impulses from sensory nerves to
motor nerves.




                                                4
Carries impulses from CNS to effector e.g. muscle to
bring about movement or gland to bring about
secretion of hormone e.g ADH




                                                       5
 Central Nervous System (CNS): brain and spinal cord


 Peripheral Nervous System (PNS): craniospinal
 nerves

 Autonomic Nervous System (ANS): nerves that
 control vital organs: heart, lungs, brain, etc.




                                                        6
The Central Nervous System includes

     White matter:         bundles of axions and dendrites
     Gray matter:          masses of nerve cell bodies


     The brain:            inside the cranium
     The spinal cord:       inside the vertebral column
                           (the “backbone”)




                 envelop the entire CNS
                (central nervous system)

   dura mater            The outer, hardest, toughest

   arachnoid                 The middle, web like

   pia mater                  The inner, thinner




                                                             7
8
 Cerebrum


 Cerebellum


 Diencephalon:- hypothalamus and thalamus


 Brainstem:-   medulla oblongata, pons and
                midbrain




                                              9
is divided into two cerebral hemispheres
has an outer surface,

or CORTEX,

made of “gray matter”




                                           10
1.   Left hemisphere:- controls the right side of the body
2.   Right hemisphere: - controls the left side of the body




is divided into parts called lobes:
1. the frontal lobe


2.   the parietal lobe

3.   the temporal lobe

4.   the occipital lobe




                                                              11
is the center for voluntary movement

     is called the “motor area” (movement)

    includes the prefrontal area,
    for intelligence, creativity, memory, and ideas.




Collects, recognizes, and organizes sensations:
feelings of
  pain

 Temperature

 Touch

 Position

 movement




                                                       12
 processes auditory (hearing) information


 stores auditory (hearing) and visual (seeing)
 memories




 is at the back of the cerebral hemisphere
 involves

    Vision

    visual memory

    eye movements




                                                  13
coordinates muscle activity
  has three parts:
  the vermis

  the right cerebellar
  hemisphere

  the left cerebellar
  hemisphere




  is located between the midbrain and the
cerebrum
                 has three parts:
                 the thalamus: receives sensory
                 information and sends it to the
                 cerebral cortex.

                    the epithalamus: contains the
                    pineal body and olfactory
                    centers.

                    the hypothalamus: connects the
                    endocrine and nervous systems.




                                                     14
connects the endocrine and nervous systems.
 controls
 the autonomic nervous system
 body temperature
 carbohydrate and fat metabolism
 appetite
 emotions
                                        w




 Pons: connects the medulla oblongata, the
 cerebellum, and cerebrum

 Midbrain: contains auditory (hearing), visual
 (sight), and muscle control centers.

 Medulla oblongata: lowest and most posterior
 (at the back of the brain)

The hindbrain includes the pons and the medulla.




                                                   15
Connects the medulla oblongata, cerebellum, and
 cerebrum
 Associates with sensory nerves: taste, hearing, and balance.


 Controls muscles of the face.




                                                                16
controls
   alertness

   heart action

   respiration (breathing)

   blood pressure



connects the CEREBRUM with the SPINAL
CORD
   the RIGHT side of the brain controls the LEFT side of the body.
   the LEFT side of the brain controls the RIGHT side of the body.




controls
 Vision

 Hearing

 Muscles




                                                                     17
 A reflex is an action that:
    occurs below the brain, within in the spinal cord
    is an automatic reaction
    is not conscious (voluntary)
    can be inborn (a baby has it at birth, such as sucking,
    swallowing, urinating)
    can be learned (such as talking,walking, driving)




   * An automatic reaction that happens without thinking about
                                it.
        * A reflex happens quickly in less than a second.




                                                                 18
 INBORN                   LEARNED
                                      reading
            knee jerk reflex          typing
            pupillary reflex          swimming
            swallowing                dancing
            coughing                  skating
            blinking                  playing football




 knee jerk: lower leg jerks when knee is tapped
 Babinski: toes curl up when sole of foot is stroked
 pupillary: pupils of eyes contract in bright light




                                                         19
 Continuation of the base of the brain
 surrounded by vertebrae

 Covered by three protective membranes
 (meninges)

 The spaces between the meninges are filled
 with cerebrospinal fluid (CSF), which
 cushion and protect the CNS




                                               20
1.   Center for many reflex actions

2.   Provides means of communication
     between the brain and the spinal
     nerves




                                        21
- Consists of cell bodies and short
 unmyelinated fibers

- H-shaped in a cross section


- Includes interneurons and portions of
 sensory neurons and motor neurons




- Consists of bundles of myelinated long
 fibers of interneurons (tracts)

- Connects the spinal to the brain


- Dorsally, contains ascending tracts taking
 information to the brain

- Ventrally, contains descending tracts
 carrying information from the brain




                                               22
- In humans, there are 12 pairs of cranial
 nerves attached to the brain

- Include the vagus nerve which has
  branches to the pharynx and larynx and
  most of the internal organs




                                             23
- In humans, there are 31 pairs if spinal
 nerves emerged from the spinal cord

- All spinal nerves are mixed nerves
  conducting impulses to and from the
  spinal cord




                                            24
 Includes all nerves that serve the internal
 organs automatically and usually without
 need for conscious intervention

 Divided into sympathetic and
 parasympathetic systems




                                                25
 Nor epinephrine (NE) is neurotransmitter


 Preganglionic fibers arises from the
    middle portion of the cord

 Accelerates heartbeat, dilates the bronchi,
    increases the breathing rate




- Acetylcholine (ACh) is neurotransmitter
-
- Preganglionic fiber is longer than
    postganglionic fiber

- Preganglionic fiber arises from the brain
    and lower portion of the cord




                                                26
THANK YOU



            27

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Nervous system by JITENDRA BHANGALE

  • 1. By: Jitendra Bhangale M.Pharm. DIPL By the end of the lesson you should be able to  Describe the transmission of impulses from senses to central nervous system and back to muscles.  Describe the reflex action and the pathway of the reflex arc.  Describe the function of reflex response.  Describe the role of the central nervous system. 1
  • 3. sensory relay motor neurone neurone neurone 3
  • 4. Carries impulses from receptors e.g pain receptors in skin to the CNS( brain or spinal cord) Carries impulses from sensory nerves to motor nerves. 4
  • 5. Carries impulses from CNS to effector e.g. muscle to bring about movement or gland to bring about secretion of hormone e.g ADH 5
  • 6.  Central Nervous System (CNS): brain and spinal cord  Peripheral Nervous System (PNS): craniospinal nerves  Autonomic Nervous System (ANS): nerves that control vital organs: heart, lungs, brain, etc. 6
  • 7. The Central Nervous System includes White matter: bundles of axions and dendrites Gray matter: masses of nerve cell bodies The brain: inside the cranium The spinal cord: inside the vertebral column (the “backbone”) envelop the entire CNS (central nervous system) dura mater The outer, hardest, toughest arachnoid The middle, web like pia mater The inner, thinner 7
  • 8. 8
  • 9.  Cerebrum  Cerebellum  Diencephalon:- hypothalamus and thalamus  Brainstem:- medulla oblongata, pons and midbrain 9
  • 10. is divided into two cerebral hemispheres has an outer surface, or CORTEX, made of “gray matter” 10
  • 11. 1. Left hemisphere:- controls the right side of the body 2. Right hemisphere: - controls the left side of the body is divided into parts called lobes: 1. the frontal lobe 2. the parietal lobe 3. the temporal lobe 4. the occipital lobe 11
  • 12. is the center for voluntary movement is called the “motor area” (movement) includes the prefrontal area, for intelligence, creativity, memory, and ideas. Collects, recognizes, and organizes sensations: feelings of pain Temperature Touch Position movement 12
  • 13.  processes auditory (hearing) information  stores auditory (hearing) and visual (seeing) memories is at the back of the cerebral hemisphere involves Vision visual memory eye movements 13
  • 14. coordinates muscle activity has three parts: the vermis the right cerebellar hemisphere the left cerebellar hemisphere is located between the midbrain and the cerebrum has three parts: the thalamus: receives sensory information and sends it to the cerebral cortex. the epithalamus: contains the pineal body and olfactory centers. the hypothalamus: connects the endocrine and nervous systems. 14
  • 15. connects the endocrine and nervous systems. controls the autonomic nervous system body temperature carbohydrate and fat metabolism appetite emotions w  Pons: connects the medulla oblongata, the cerebellum, and cerebrum  Midbrain: contains auditory (hearing), visual (sight), and muscle control centers.  Medulla oblongata: lowest and most posterior (at the back of the brain) The hindbrain includes the pons and the medulla. 15
  • 16. Connects the medulla oblongata, cerebellum, and cerebrum Associates with sensory nerves: taste, hearing, and balance. Controls muscles of the face. 16
  • 17. controls alertness heart action respiration (breathing) blood pressure connects the CEREBRUM with the SPINAL CORD the RIGHT side of the brain controls the LEFT side of the body. the LEFT side of the brain controls the RIGHT side of the body. controls Vision Hearing Muscles 17
  • 18.  A reflex is an action that: occurs below the brain, within in the spinal cord is an automatic reaction is not conscious (voluntary) can be inborn (a baby has it at birth, such as sucking, swallowing, urinating) can be learned (such as talking,walking, driving) * An automatic reaction that happens without thinking about it. * A reflex happens quickly in less than a second. 18
  • 19.  INBORN  LEARNED reading knee jerk reflex typing pupillary reflex swimming swallowing dancing coughing skating blinking playing football  knee jerk: lower leg jerks when knee is tapped  Babinski: toes curl up when sole of foot is stroked  pupillary: pupils of eyes contract in bright light 19
  • 20.  Continuation of the base of the brain surrounded by vertebrae  Covered by three protective membranes (meninges)  The spaces between the meninges are filled with cerebrospinal fluid (CSF), which cushion and protect the CNS 20
  • 21. 1. Center for many reflex actions 2. Provides means of communication between the brain and the spinal nerves 21
  • 22. - Consists of cell bodies and short unmyelinated fibers - H-shaped in a cross section - Includes interneurons and portions of sensory neurons and motor neurons - Consists of bundles of myelinated long fibers of interneurons (tracts) - Connects the spinal to the brain - Dorsally, contains ascending tracts taking information to the brain - Ventrally, contains descending tracts carrying information from the brain 22
  • 23. - In humans, there are 12 pairs of cranial nerves attached to the brain - Include the vagus nerve which has branches to the pharynx and larynx and most of the internal organs 23
  • 24. - In humans, there are 31 pairs if spinal nerves emerged from the spinal cord - All spinal nerves are mixed nerves conducting impulses to and from the spinal cord 24
  • 25.  Includes all nerves that serve the internal organs automatically and usually without need for conscious intervention  Divided into sympathetic and parasympathetic systems 25
  • 26.  Nor epinephrine (NE) is neurotransmitter  Preganglionic fibers arises from the middle portion of the cord  Accelerates heartbeat, dilates the bronchi, increases the breathing rate - Acetylcholine (ACh) is neurotransmitter - - Preganglionic fiber is longer than postganglionic fiber - Preganglionic fiber arises from the brain and lower portion of the cord 26
  • 27. THANK YOU 27