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Option B - Physiology of
       Exercise
             Part I
   Muscles/Bones & Movement
Locomotion
Skeletal and Muscular Systems
The
Skeletal
 System
Types of Connective Tissue
General Functions

• Shape and Support
• Protect soft organs
• Working with muscles to
  produce movement
• Storage of minerals: Ca and P
• Produce blood cells
Joints,
Ligaments,
     and
  Tendons
Joints

• Ball and
  Socket
• Pivot


• Hinge
• Gliding

• Immovable

• Saddle

• Ellipsoidal
Knee and Hip Joint
Knee and Hip Joint
Knee –
  – Hinge Joint – one way movement… Flex and
    extend
  – Bones involved: Femur, tibia, fibula, patella

Hip
  - Ball and Socket Joint – multiple movement:
    Flex, Extend, Adduction, Abduction, Rotation
  - Bones involved – Pelvis and Femur
Ligaments


Connect
BONE
TO
BONE
Tendons


CONNECT
MUSCLE
TO BONE
The Elbow Joint – It’s IB Required
Elbow Parts
• Bones: Ulna , Radius, Humerus
• Joint: Hinge Joint
• Movement: Flex, Extend, Pronate,
  Supinate
  – Principle Muscles involved: bicep and
    Triceps – antagonistic
• Synovial Fluid – lubricates to reduce
  friction
• Articular (Joint) Capsule – seals joint,
  provides stability
Skeletal
  Muscle
Contractions
Muscle Tissue

•Muscle tissue consists
 of cells that have the
 ability to CONTRACT
 and exert a PULLING
 FORCE.
Types of Muscle – Skeletal/Striated
• LARGE…contain…blood vessels, nerves,
  and connective tissue.
• Voluntary movement.
• Fibers contain striations.
• Have many nuclei
• Sarcoplasmic reticulum – ER in muscle
  cells. Stores and pumps CALCIUM.
• Sarcolemma – cell membrane of muscle
  plus collagen
The EM View of the Skeletal Muscle

You must be able to draw this:
Muscle Contractions
Structure of a Skeletal Muscle
• Muscle tissue is made up of 2 types of
  proteins
  – Actin – molecules that form LONG, THIN
    chains. (Light Band)
  – Myosin – molecules that bundle together to
    form THICK fibers. (Dark Band)
• Actin and Myosin are arranged in
  structures called SARCOMERES
• In a muscle, sarcomeres group to form a
  threadlike structure: MYOFIBRIL
• Mitochondria between myofibril
Muscle Contractions – Building of
            Muscle
• Many myofibrils bundle together with cell
  organelles to form a MUSCLE CELL
• Muscles cells grouped together to form a
  FASCICLE.
• Groups of Fascicles = whole muscle
• Membrane around muscle = sarcolemma
_________________________________

Actin and myosin   sarcomere   myofibril   muscle cell

Fascicle      muscle
Muscle
IB Required – Know How To Draw
Muscle contraction
Stages in Muscle Contraction

• A sarcomere is the functional unit of
  muscle contraction.
• When muscle cells contract the light and
  dark bands get closer.
  – Why? – myosin and actin filaments
    interact to shorten the length of a
    sarcomere.
• Two proteins on actin: tropomyosin
  and troponin regulate the binding of
  actin and myosin.
Actin Binding Site
Stages in Muscle Contraction
Relaxed Skeletal Muscle: protein – tropomyosin blocks
    binding sites on actin.
Regulatory Proteins (Troponin & Tropomyosin) In Skeletal Muscle Fibers

When a motor neuron stimulates a muscle fiber:
•  “Stimulus” – Ca+ ions released from sarcoplasmic
   reticulum.
•  Ca+ ions bind to protein - troponin --- causes
   tropomyosin to move to expose binding sites on
   actin
•  This allows the myosin heads to bind…..

CONTRACTION:
•  Myosin filaments have “heads” which form CROSS
   BRIDGES when attached to binding sites on actin.
Stages: Mechanism of Muscle
              Contraction
•   ATP attaches to myosin head and causes them
    to break the cross bridges by detaching them
    from the binding site.
•   ATP is hydrolyzed. Causes he myosin head to
    change its “angle” The heads are “bent” and
    store the energy released.
•   The heads attach to binding sites on actin that
    are further from the center of the sarcomere.
•   The heads push the actin inward toward the
    center of the sarcomere: POWER STROKE!
Stages: Mechanism of Muscle
           Contraction
The synchronized shortening of
 sarcomeres along the whole muscle fiber
 causes the fiber….the whole muscle to
 contract.
When thousands of actin and myosin
 filaments interact… the entire muscle
 shortens.

THIS IS THE SLIDING FILAMENT THEORY
           Muscle contraction
Muscle contraction
END
Structure of Human Bones

• Made of living cells, collagen, and
  inorganic compounds.
• Bone Cells are arranged:
    • Periosteum – outer layer of connective tissue
    • Contain blood vessels
    • Compact Bone – thick layer. Dense.
    • Haversian Canals – in compact bone. Contain blood vessels
      and nerves.
    • Spongy Bone – less dense. Found ar the end of most long
      bones. Helps to add strength without mass.
    • Bone Marrow – inside bone cavities. Yellow( fat cells) and
      Red (makes blood cells)

• Ossification – Bone formation
Structure of Human Bones
BodySmart: Online Anatomy and Physiology

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Locomotion master 2009

  • 1. Option B - Physiology of Exercise Part I Muscles/Bones & Movement
  • 4.
  • 6. General Functions • Shape and Support • Protect soft organs • Working with muscles to produce movement • Storage of minerals: Ca and P • Produce blood cells
  • 7. Joints, Ligaments, and Tendons
  • 8. Joints • Ball and Socket • Pivot • Hinge • Gliding • Immovable • Saddle • Ellipsoidal
  • 9. Knee and Hip Joint
  • 10. Knee and Hip Joint Knee – – Hinge Joint – one way movement… Flex and extend – Bones involved: Femur, tibia, fibula, patella Hip - Ball and Socket Joint – multiple movement: Flex, Extend, Adduction, Abduction, Rotation - Bones involved – Pelvis and Femur
  • 13. The Elbow Joint – It’s IB Required
  • 14.
  • 15.
  • 16.
  • 17. Elbow Parts • Bones: Ulna , Radius, Humerus • Joint: Hinge Joint • Movement: Flex, Extend, Pronate, Supinate – Principle Muscles involved: bicep and Triceps – antagonistic • Synovial Fluid – lubricates to reduce friction • Articular (Joint) Capsule – seals joint, provides stability
  • 19. Muscle Tissue •Muscle tissue consists of cells that have the ability to CONTRACT and exert a PULLING FORCE.
  • 20.
  • 21.
  • 22. Types of Muscle – Skeletal/Striated • LARGE…contain…blood vessels, nerves, and connective tissue. • Voluntary movement. • Fibers contain striations. • Have many nuclei • Sarcoplasmic reticulum – ER in muscle cells. Stores and pumps CALCIUM. • Sarcolemma – cell membrane of muscle plus collagen
  • 23. The EM View of the Skeletal Muscle You must be able to draw this:
  • 24.
  • 26. Structure of a Skeletal Muscle • Muscle tissue is made up of 2 types of proteins – Actin – molecules that form LONG, THIN chains. (Light Band) – Myosin – molecules that bundle together to form THICK fibers. (Dark Band) • Actin and Myosin are arranged in structures called SARCOMERES • In a muscle, sarcomeres group to form a threadlike structure: MYOFIBRIL • Mitochondria between myofibril
  • 27. Muscle Contractions – Building of Muscle • Many myofibrils bundle together with cell organelles to form a MUSCLE CELL • Muscles cells grouped together to form a FASCICLE. • Groups of Fascicles = whole muscle • Membrane around muscle = sarcolemma _________________________________ Actin and myosin sarcomere myofibril muscle cell Fascicle muscle
  • 28.
  • 30. IB Required – Know How To Draw
  • 32.
  • 33.
  • 34. Stages in Muscle Contraction • A sarcomere is the functional unit of muscle contraction. • When muscle cells contract the light and dark bands get closer. – Why? – myosin and actin filaments interact to shorten the length of a sarcomere. • Two proteins on actin: tropomyosin and troponin regulate the binding of actin and myosin.
  • 36.
  • 37. Stages in Muscle Contraction Relaxed Skeletal Muscle: protein – tropomyosin blocks binding sites on actin. Regulatory Proteins (Troponin & Tropomyosin) In Skeletal Muscle Fibers When a motor neuron stimulates a muscle fiber: • “Stimulus” – Ca+ ions released from sarcoplasmic reticulum. • Ca+ ions bind to protein - troponin --- causes tropomyosin to move to expose binding sites on actin • This allows the myosin heads to bind….. CONTRACTION: • Myosin filaments have “heads” which form CROSS BRIDGES when attached to binding sites on actin.
  • 38. Stages: Mechanism of Muscle Contraction • ATP attaches to myosin head and causes them to break the cross bridges by detaching them from the binding site. • ATP is hydrolyzed. Causes he myosin head to change its “angle” The heads are “bent” and store the energy released. • The heads attach to binding sites on actin that are further from the center of the sarcomere. • The heads push the actin inward toward the center of the sarcomere: POWER STROKE!
  • 39. Stages: Mechanism of Muscle Contraction The synchronized shortening of sarcomeres along the whole muscle fiber causes the fiber….the whole muscle to contract. When thousands of actin and myosin filaments interact… the entire muscle shortens. THIS IS THE SLIDING FILAMENT THEORY Muscle contraction
  • 41.
  • 42.
  • 43. END
  • 44. Structure of Human Bones • Made of living cells, collagen, and inorganic compounds. • Bone Cells are arranged: • Periosteum – outer layer of connective tissue • Contain blood vessels • Compact Bone – thick layer. Dense. • Haversian Canals – in compact bone. Contain blood vessels and nerves. • Spongy Bone – less dense. Found ar the end of most long bones. Helps to add strength without mass. • Bone Marrow – inside bone cavities. Yellow( fat cells) and Red (makes blood cells) • Ossification – Bone formation
  • 46. BodySmart: Online Anatomy and Physiology

Notas do Editor

  1. thin filaments (myofibrils) extending from sarcomere ends (Z lines) toward center (M line) mysosin: thick filaments (myofibrils) extending from sarcomere center (M line) toward ends (A band = length of myosin) cross-bridge formation: myosin filaments overlap with actin filaments mysosin arms attach to actin, forming cross-bridges movement and breakage: movements of myosin arms ratchet along actin, contracting sarcomere myosin breaks attachment, reattaches to actin, and repeats ratcheting contraction of sarcomere ATP: ATP phosphorylation of myosin heads provides energy for ratcheting power stroke of muscle contraction Ca2+ ions: released from sarcoplasmic reticulum in response to neural depolarization attach to troponin