The document discusses various challenges in diagnosing premature rupture of membranes (PROM). Current diagnostic methods like nitrazine tests, ferning tests, ultrasound and amniotic dye infusion are inaccurate or invasive. There is a need for an easy and accurate diagnostic test to correctly identify PROM and prevent misdiagnoses that can harm both mother and baby. Research into proteins in amniotic fluid showed promise but failed to produce a reliable diagnostic due to variability between patients. The problems of inaccurate or difficult testing for PROM remain unresolved.