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MR Imaging of   Cystic Lesion of the Pancreas Present by : Ekksit Srithammasit, MD Kalb et al : Departments of Radiology , Surgery, and Pathology, Emory University School of Medicine, Atlanta. 2009;
Introduction ,[object Object],[object Object],[object Object],[object Object]
Introduction ,[object Object],[object Object],[object Object]
Introduction ,[object Object],[object Object],[object Object],[object Object],[object Object],MRI = best suited for evaluating these features.
Imaging Modalities ,[object Object],[object Object],[object Object],[object Object],[object Object],Presence or absence of calcification :  not  critical factor in the differentiation of pancreatic cyst. ,[object Object],[object Object],[object Object],[object Object]
Imaging Modalities ,[object Object],[object Object],[object Object],[object Object],MRI = best suited for evaluating these features.
 
Table of Contents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MR Imaging Techniques ,[object Object],[object Object],[object Object],[object Object]
MR Imaging Techniques ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MR Imaging Techniques ,[object Object],[object Object],[object Object]
MR Imaging Techniques ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Table of Contents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Table of Contents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pseudocysts ,[object Object],[object Object],[object Object]
Pseudocysts ,[object Object],[object Object],[object Object],[object Object]
Pseudocysts ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pseudocysts No vascularized soft-tissue elements are present within pseudocysts, and  if vascularized elements are seen within a cystic lesion on contrast-enhanced MR images, the lesion is not a pseudocyst.
Pseudocysts ,[object Object],[object Object],[object Object]
Pancreatic pseudocyst.  (a) a simple fluid collection.  (b) with chronic pancreatitis.
Pancreatic pseudocyst with F/U 2 months (a) Complex cyst with a fluid-debris level  (b) Resolution of the pseudocyst.
Pancreatic pseudocyst Common findings in pancreatic pseudocysts: hemorrhage, protein deposition.
Table of Contents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Serous Cystadenomas ,[object Object],[object Object],[object Object],[object Object],[object Object]
Serous Cystadenomas ,[object Object],[object Object],[object Object],[object Object],[object Object]
Serous Cystadenomas ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Serous Cystadenomas ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
C luster of many small cysts
Serous cystadenomas.  Calcified scar and enhancement of the internal septa
Serous cystadenomas.  Enhancement of the internal septa
Oligocystic serous cystadenoma.  Large cysts and lacks internal enhancing soft-tissue components. Imaging features overlap with mucinous cystadenoma
Table of Contents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Table of Contents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Mucinous Nonneoplastic Cysts ,[object Object],[object Object],Mucin Containing Cyst ,[object Object],[object Object],[object Object],[object Object]
Mucinous Nonneoplastic Cysts ,[object Object],[object Object],[object Object],[object Object],Mucin Containing Cyst
Mucinous Nonneoplastic Cysts Mucin Containing Cyst DDx with mucinous cystadenomas. May be indistinguishable, especially if the cyst is  large and has a thick wall.  Mucinous cystadenomas Mucinous Nonneoplastic Cysts
Mucin Containing Cyst Mucinous nonneoplastic pancreatic cyst .  Bi-lobed, smoothly marginated cyst  No enhancing soft-tissue elements.
Mucinous Cystadenomas ,[object Object],[object Object],[object Object],Mucin Containing Cyst sampling of the cyst lining  must be performed
Mucinous Cystadenomas ,[object Object],[object Object],[object Object],[object Object],Mucin Containing Cyst
Mucinous Cystadenomas ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Mucin Containing Cyst
Mucin Containing Cyst Mucinous cystadenoma.  A single large lobulated cyst without internal enhancing soft-tissue elements.
Mucin Containing Cyst Mucinous cystadenoma.  A rounded thick-walled cystic structure with thickened enhancing septa.
Mucinous Cystadenocarcinomas ,[object Object],[object Object],[object Object],[object Object],Mucin Containing Cyst ,[object Object],[object Object],[object Object]
Mucinous Cystadenocarcinomas ,[object Object],[object Object],[object Object],[object Object],Mucin Containing Cyst
Mucin Containing Cyst Mucinous cystadenocarcinoma.  A  large, complex cystic lesion  with  enhancing mural soft-tissue elements .
Pancreatic IPMNs ,[object Object],[object Object],[object Object],[object Object],[object Object],Mucin Containing Cyst
Pancreatic IPMNs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Mucin Containing Cyst
Pancreatic IPMNs ,[object Object],[object Object],[object Object],Mucin Containing Cyst
Pancreatic IPMNs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Mucin Containing Cyst
Mucin Containing Cyst IPMN with involvement of the main pancreatic duct. .  D iffuse dilatation of the main pancreatic duct with a focal cystic lesion . The lesion communicates with the distended main pancreatic duct .
Mucin Containing Cyst IPMN with involvement of the side-branches.  F ocal dilatation of ductal side-branches in the pancreatic head .
Mucin Containing Cyst Invasive adenocarcinoma in association with an IPMN.  A  complex cystic lesion with ductal communication and enhancing soft tissue  component.
Table of Contents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Table of Contents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Lymphoepithelial Cysts ,[object Object],[object Object],[object Object],[object Object],[object Object]
Table of Contents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Table of Contents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Ductal adenocarcinoma  with cystic features ,[object Object],[object Object],[object Object],[object Object],[object Object],Solid Pancreatic Tumor with Cystic Degeneration
Ductal adenocarcinoma  with cystic features ,[object Object],[object Object],[object Object],Solid Pancreatic Tumor with Cystic Degeneration
Ductal adenocarcinoma  with cystic features ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Solid Pancreatic Tumor with Cystic Degeneration
Ductal adenocarcinoma  with cystic features ,[object Object],[object Object],[object Object],[object Object],[object Object],Solid Pancreatic Tumor with Cystic Degeneration
Solid Pancreatic Tumor with Cystic Degeneration Ductal adenocarcinoma with cystic changes.  A   poorly vascularized infiltrative   tumor with a central necrosis and pseudocyst.
Solid Pancreatic Tumor with Cystic Degeneration Ductal adenocarcinoma with cystic changes.  A   pancreatic tumor obstructed pancreatic and common bile duct with distention of the pancreatic duct side-branches.
Solid Pseudopapillary Tumors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Solid Pancreatic Tumor with Cystic Degeneration
Solid Pseudopapillary Tumors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Solid Pancreatic Tumor with Cystic Degeneration
Solid Pseudopapillary Tumors ,[object Object],[object Object],[object Object],Solid Pancreatic Tumor with Cystic Degeneration However, because all three entities require surgical resection, their preoperative differentiation may not  be important in the clinical setting.
Solid pseudopapillary tumor of the pancreas. A   gradual enhancing solid tumor with internal hemorrhage. Solid Pancreatic Tumor with Cystic Degeneration
Solid pseudopapillary tumor of the pancreas. varying degrees of cystic degeneration Solid Pancreatic Tumor with Cystic Degeneration
Cystic Neuroendocrine Tumors ,[object Object],[object Object],[object Object],[object Object],Solid Pancreatic Tumor with Cystic Degeneration
Cystic Neuroendocrine Tumors ,[object Object],Solid Pancreatic Tumor with Cystic Degeneration
Cystic Neuroendocrine Tumors ,[object Object],[object Object],[object Object],Solid Pancreatic Tumor with Cystic Degeneration A patient with a  cystic   neuroendocrine tumor is significantly more likely to have an  underlying multiple endocrine neoplasia syndrome than a patient with a uniformly  solid neuroendocrine tumor.
Cystic neuroendocrine tumor.  A   well define cyst with avidly enhancing thickening rim on arterial phase image. Solid Pancreatic Tumor with Cystic Degeneration
Table of Contents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Table of Contents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusions ,[object Object],[object Object],[object Object],[object Object]
 
 
 
 
 
 
 
 
 
 
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
 

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Pancreatic cystic lesion by xiu

  • 1. MR Imaging of Cystic Lesion of the Pancreas Present by : Ekksit Srithammasit, MD Kalb et al : Departments of Radiology , Surgery, and Pathology, Emory University School of Medicine, Atlanta. 2009;
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  • 18. Pseudocysts No vascularized soft-tissue elements are present within pseudocysts, and if vascularized elements are seen within a cystic lesion on contrast-enhanced MR images, the lesion is not a pseudocyst.
  • 19.
  • 20. Pancreatic pseudocyst. (a) a simple fluid collection. (b) with chronic pancreatitis.
  • 21. Pancreatic pseudocyst with F/U 2 months (a) Complex cyst with a fluid-debris level (b) Resolution of the pseudocyst.
  • 22. Pancreatic pseudocyst Common findings in pancreatic pseudocysts: hemorrhage, protein deposition.
  • 23.
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  • 25.
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  • 27.
  • 28. C luster of many small cysts
  • 29. Serous cystadenomas. Calcified scar and enhancement of the internal septa
  • 30. Serous cystadenomas. Enhancement of the internal septa
  • 31. Oligocystic serous cystadenoma. Large cysts and lacks internal enhancing soft-tissue components. Imaging features overlap with mucinous cystadenoma
  • 32.
  • 33.
  • 34.
  • 35.
  • 36. Mucinous Nonneoplastic Cysts Mucin Containing Cyst DDx with mucinous cystadenomas. May be indistinguishable, especially if the cyst is large and has a thick wall. Mucinous cystadenomas Mucinous Nonneoplastic Cysts
  • 37. Mucin Containing Cyst Mucinous nonneoplastic pancreatic cyst . Bi-lobed, smoothly marginated cyst No enhancing soft-tissue elements.
  • 38.
  • 39.
  • 40.
  • 41. Mucin Containing Cyst Mucinous cystadenoma. A single large lobulated cyst without internal enhancing soft-tissue elements.
  • 42. Mucin Containing Cyst Mucinous cystadenoma. A rounded thick-walled cystic structure with thickened enhancing septa.
  • 43.
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  • 45. Mucin Containing Cyst Mucinous cystadenocarcinoma. A large, complex cystic lesion with enhancing mural soft-tissue elements .
  • 46.
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  • 48.
  • 49.
  • 50. Mucin Containing Cyst IPMN with involvement of the main pancreatic duct. . D iffuse dilatation of the main pancreatic duct with a focal cystic lesion . The lesion communicates with the distended main pancreatic duct .
  • 51. Mucin Containing Cyst IPMN with involvement of the side-branches. F ocal dilatation of ductal side-branches in the pancreatic head .
  • 52. Mucin Containing Cyst Invasive adenocarcinoma in association with an IPMN. A complex cystic lesion with ductal communication and enhancing soft tissue component.
  • 53.
  • 54.
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  • 56.
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  • 62. Solid Pancreatic Tumor with Cystic Degeneration Ductal adenocarcinoma with cystic changes. A poorly vascularized infiltrative tumor with a central necrosis and pseudocyst.
  • 63. Solid Pancreatic Tumor with Cystic Degeneration Ductal adenocarcinoma with cystic changes. A pancreatic tumor obstructed pancreatic and common bile duct with distention of the pancreatic duct side-branches.
  • 64.
  • 65.
  • 66.
  • 67. Solid pseudopapillary tumor of the pancreas. A gradual enhancing solid tumor with internal hemorrhage. Solid Pancreatic Tumor with Cystic Degeneration
  • 68. Solid pseudopapillary tumor of the pancreas. varying degrees of cystic degeneration Solid Pancreatic Tumor with Cystic Degeneration
  • 69.
  • 70.
  • 71.
  • 72. Cystic neuroendocrine tumor. A well define cyst with avidly enhancing thickening rim on arterial phase image. Solid Pancreatic Tumor with Cystic Degeneration
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Notas do Editor

  1. Comparison of soft-tissue contrast capabilities of CT and MR imaging. (1a) Axial contrast-enhanced CT image obtained in a 35-year-old man with acute pancreatitis depicts a fluid collection without internal complexity (arrow) in the left anterior pararenal space. (1b) Axial T2-weighted MR image obtained within 24 hours shows markedly complicated internal fluid signal within the collection ( * ), a finding indicative of complexity. MR images obtained after the administration of a gadolinium-based contrast material did not show internal enhancement. The diagnosis was pseudocyst. (2a) Axial contrast-enhanced CT image (5-mm section) obtained in a 68-year-old man demonstrates a focal cystic lesion in the body of the pancreas (arrow). Poor depiction of the internal architecture of the lesion limited further characterization. (2b) Axial single-shot MR cholangiopancreatographic image (8-mm section) clearly shows a cluster of many small cysts (arrow), findings in keeping with benign serous cystadenoma.
  2. Pancreatic pseudocyst. (a) Axial T2-weighted single-shot MR image obtained in a 45-year-old woman demonstrates a well-circumscribed, unilocular cyst in the pancreatic head. The cyst has internal signal intensity indicative of a simple fluid collection. (b) Delayed contrast-enhanced 3D GRE MR image shows chronic fibrotic changes in the pancreatic parenchyma (arrows), features suggestive of chronic pancreatitis. Surgical resection revealed a benign pseudocyst.
  3. Pancreatic pseudocyst. (a) Axial T2WI obtained in a 70-year-old woman shows a complex cyst with a fluid-debris level (arrowhead) in the pancreatic head, a finding suggestive of a pseudocyst. (b) Axial T2-weighted MR image obtained 2 months later demonstrates resolution of the pseudocyst.
  4. Pancreatic pseudocyst. Axial unenhanced 3D T1-weighted GRE (a) and coronal T2-weighted (b) MR images obtained in a 45-year-old man depict a large cyst along the anterior pancreatic margin (arrows in a) with increased T1 signal intensity that may be secondary to hemorrhage, protein deposition, or both, common findings in pancreatic pseudocysts. Contrast-enhanced MR images showed no internal enhancement of the pseudocyst.
  5. Axial single-shot MR cholangiopancreatographic image (8-mm section) clearly shows a cluster of many small cysts (arrow), findings in keeping with benign serous cystadenoma.
  6. Serous cystadenomas. Axial T2-weighted MR images obtained in a 66-year-old man (6a) and a 66-year-old woman (7a) show well-marginated pancreatic lesions, each consisting of a cluster of many small cysts separated by thin septa. In 6a, the central focal region of T2 signal hypointensity (arrowhead) from which the thin septa radiate is in keeping with a calcified scar. (6b, 7b) Axial delayed contrast-enhanced 3D GRE MR images obtained in the same two patients demonstrate thin enhancement of the internal septa (arrows), a finding suggestive of fibrous tissue. These are all features of benign serous cystadenomas.
  7. Serous cystadenomas. Axial T2-weighted MR images obtained in a 66-year-old man (6a) and a 66-year-old woman (7a) show well-marginated pancreatic lesions, each consisting of a cluster of many small cysts separated by thin septa. In 6a, the central focal region of T2 signal hypointensity (arrowhead) from which the thin septa radiate is in keeping with a calcified scar. (6b, 7b) Axial delayed contrast-enhanced 3D GRE MR images obtained in the same two patients demonstrate thin enhancement of the internal septa (arrows), a finding suggestive of fibrous tissue. These are all features of benign serous cystadenomas.
  8. Oligocystic serous cystadenoma. Axial T2-weighted (a) and delayed contrast-enhanced 3D GRE (b) MR images obtained in a 26-year-old woman show a cystic pancreatic lesion (arrow) that consists of several large cysts and lacks internal enhancing soft-tissue components. This oligocystic variant of serous cystadenoma (a diagnosis confirmed with surgical resection) has imaging features that overlap with those of mucinous cystadenom ฟ
  9. Mucinous nonneoplastic pancreatic cyst in a 56-year-old woman. Axial T2-weighted MR image demonstrates a bilobed, smoothly marginated cyst (arrowhead) with simple fluid content. (b) Axial contrastenhanced 3D GRE MR image shows no enhancing soft-tissue elements or thickening of the cyst wall. The benign imaging features correlate with the histopathologic diagnosis of a mucinous nonneoplastic cyst.
  10. Mucinous cystadenoma. (10a) Axial T2-weighted fat-saturated MR image obtained in a 56-yearold woman depicts a single large lobulated cyst (arrow) in the pancreatic neck, a finding suggestive of mucinous cystadenoma. (10b) Coronal contrast-enhanced T1-weighted MR image shows no internal enhancing soft-tissue elements suggestive of carcinoma. (11a) Axial T2-weighted MR image obtained in a 48-year-old woman shows a rounded thick-walled cystic structure (arrow) in the pancreatic tail. (11b) Contrast-enhanced 3D GRE MR image shows multiple thickened enhancing septa along the posterior margin of the cyst (arrowheads).
  11. Mucinous cystadenoma. (10a) Axial T2-weighted fat-saturated MR image obtained in a 56-yearold woman depicts a single large lobulated cyst (arrow) in the pancreatic neck, a finding suggestive of mucinous cystadenoma. (10b) Coronal contrast-enhanced T1-weighted MR image shows no internal enhancing soft-tissue elements suggestive of carcinoma. (11a) Axial T2-weighted MR image obtained in a 48-year-old woman shows a rounded thick-walled cystic structure (arrow) in the pancreatic tail. (11b) Contrast-enhanced 3D GRE MR image shows multiple thickened enhancing septa along the posterior margin of the cyst (arrowheads).
  12. Mucinous cystadenocarcinoma. (a) Axial T2-weighted MR image obtained in a 55-year-old man shows a large, complex cystic lesion (arrow) in the pancreatic head. (b, c) u nenhanced (b) and contrast-enhanced (c) 3D GRE MR images show enhancing mural soft-tissue elements (arrowheads in c ) projecting toward the cyst center, features that represent carcinomatous components.
  13. IPMN with involvement of the main pancreatic duct. Axial T2-weighted MR images obtained in a 70-year-old man ( a at a lower level than b ) show diffuse dilatation of the main pancreatic duct with a focal cystic lesion in the pancreatic head. The lesion communicates with the distended main pancreatic duct (arrowhead in a ). These findings represent an IPMN with involvement of the main pancreatic duct.
  14. IPMN. Axial T2-weighted MR image obtained in a 72-year-old man demonstrates focal dilatation of ductal side-branches in the pancreatic head (arrow), findings that represent a small side-branch IPMN.
  15. Invasive adenocarcinoma in association with an IPMN. Axial T2-weighted (a) and contrast-enhanced 3D GRE (b) MR images obtained in a 62-year-old woman show a complex cystic lesion (arrow in a ) in the pancreatic head with ductal communication and an enhancing posterior margin of soft tissue (arrowheads in b ).
  16. Ductal adenocarcinoma with cystic changes. (16) Coronal T2-weighted (a) and contrastenhanced 3D GRE (b) MR images obtained in a 62-year-old woman show an infiltrative poorly vascularized tumor in the pancreatic head (arrows) with a central accumulation of complex fluid (arrowhead in a), a finding indicative of necrosis. Dilatation of the pancreatic duct and delayed uptake of contrast material in the pancreatic tail (arrowhead in b) are suggestive of chronic pancreatitis due to ductal obstruction by the tumor. A pseudocyst (* in b) dissects along the undersurface of the left hepatic lobe. (17a) Coronal single-shot thicksection MR cholangiopancreatographic image obtained in a 76-year-old woman shows a severe obstruction of both the pancreatic duct and the biliary system. (17b) Axial T2-weighted MR image shows the obstructing adenocarcinoma in the pancreatic head (arrowheads) with a focal cystic lesion along the medial margin (arrow), a finding indicative of distention of the pancreatic duct side-branches in the uncinate process.
  17. (17a) Coronal single-shot thick section MR cholangiopancreatographic image obtained in a 76-year-old woman shows a severe obstruction of both the pancreatic duct and the biliary system. (17b) Axial T2-weighted MR image shows the obstructing adenocarcinoma in the pancreatic head (arrowheads) with a focal cystic lesion along the medial margin (arrow), a finding indicative of distention of the pancreatic duct side-branches in the uncinate process.
  18. Solid pseudopapillary tumor of the pancreas. Axial T2-weighted MR image obtained in a 38-year-old man shows a large, predominantly solid tumor in the pancreatic head, with a central focus of T2 signal hypointensity (arrowhead) that appeared hyperintense on T1-weighted unenhanced images and correlated with a focal hemorrhage at histologic analysis. (b, c) Axial contrast-enhanced GRE MR images from arterial (b) and delayed (c) phases show a gradual accumulation of contrast material in the tumor (arrow).
  19. (20) Axial (a, b) and coronal (c) T2-weighted MR images obtained in three patients depict solid pseudopapillary tumors with varying degrees of cystic degeneration: one predominantly solid (arrow in a ), one mixed solid and cystic (arrow in b ), and one predominantly cystic (arrow in c ).
  20. Cystic neuroendocrine tumor. Axial T2-weighted MR image obtained in a 72-year-old man shows a well-circumscribed cystic lesion (arrow). (b) Arterial phase 3D GRE MR image shows a slightly thickened rim of well-vascularized enhancing tissue (arrowheads) around the tumor.
  21. a
  22. c
  23. a
  24. d
  25. b
  26. b
  27. c
  28. d