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The 12th International Review of
                                                                                    Bipolar Disorders
                                                                                         21 - 23 May 2012 Nice, France
                                                                                                         www.irbd.org


Day 1 - Monday 21 May 2012 - Proposed Programme
08.30   Registration/POSTER SET UP

09.00   IRBD 2012 Welcome and Introduction
        President: Prof J M Azorin (Fr)
        Chairman: Dr E Hantouche (Fr)
        Local committee: Prof J Allilaire (Fr), Prof D Pringuey (Fr), Dr P Robert (Fr)

09.15   Opening Plenary : The Future of Bipolar Spectrum
        Chair:     Dr E Hantouche (Fr)
        Speaker:   Prof H Akiskal (US)

09.45   Plenary 1: Bipolar Spectrum from Bridge Study and International Studies
        Chair:     Prof A Young (UK)
        Speaker:   Prof J Angst (Ch)

10.15   Coffee

10.45   European Bipolar Forum I: New Insights in Soft Bipolarity and Emotion Regulation
        Chairs:          Prof J M Azorin (Fr)

        Validating cyclothymia in youth
        Prof E Youngstrom (US) / Dr A Van Meter (US)

        Intra-bipolar dichotomy: specificity of cyclothymia
        Dr E Hantouche (Fr)

        The affective and emotional composite temperament model and scale (AFECTS): utility for the evalua-
        tion and treatment of mood disorders
        Dr D Lara (Br)

        Temperaments across the spectra of mood disorders
        Prof J Angst (Ch)


12.45   Lunch POSTER VIEWING

13.45   Plenary 2: Stress and Bipolar Disorder
        Chair:     Prof A Swann (US)
        Speaker:   Prof A Young (UK)



14.15   Plenary 3: Subsyndromal Bipolar in the New Nosology
        Chair:     Prof E Karam (Lb)
        Speaker:   Prof A Okasha (Eg)




                                                                                                               Cont../...




 A Cortex Congress Conference                       PROGRAMME CO-CHAIRS
The 12th International Review of
                                                                            Bipolar Disorders
                                                                               21 - 23 May 2012 Nice, France
                                                                                               www.irbd.org


Day 1 Cont../...
14.45   Science Update 1: Bipolar Disorders: Poised for     Interactive 1: Mania Phenotypes
        discovery?                                          Chair:       Prof D Pringuey (Fr)
        Chair:     Prof J Allilaire (Fr)
                                                            Mania phenotypes: findings from cluster analy-
        Addressing the likelihood to express clinical       ses
        symptoms from a genetic tendency                    Prof J Azorin (Fr)
        Prof J Kelsoe (US)
                                                            Hyperthymic vs clyclothymic BP-I disorder
        New perspectives from research to care and pre-     Prof G Perugi (I)
        vention
        Prof M Leboyer (Fr)

15.45   Interactive 2: Management of difficult cases in     Science Update 2: French Networks: Research
        Bipolar Disorder                                    on Affective Disorders
                                                            Chair:      Prof F Bellivier (Fr)
        Mania in neuropsychiatric disorders. Focus in
        post-stroke mania                                   French Expert Centre Network: first data
        Prof M L Figueira (P)                               Prof C Henry (Fr)

        Mania Dr J Cookson (UK)                             Functional brain imaging of unipolar and bipolar
                                                            depression: differences and similarities
        ADHD/bipolar patients; distinctions and similari-   Prof Fossatti (Fr)
        ties Dr V Syrstad/Dr K Odegaard (No)
                                                            Comorbid addiction in Bipolar Disorder: results
        Postpartum Depression                               from the French Expert Centre Network
        Dr J Masmoudi (Fr)                                  Prof F Bellivier (Fr)

16.45   Refreshments

17.15   Interactive 3: Assessment of Hypomania:             Interactive 4: Geriatric Bipolarity
        Methodological Issues                               Chairs:      Prof J M Azorin (Fr)/Dr P H Robert (Fr)
        Chair:       Prof E Karam (Lb)
                                                            Introducing “BP-VI” within the Bipolar Spectrum
        BP-II recognition in primary care                   Dr D Lara (Fr)
        Prof Z Rihmer (Hu)
                                                            Treating late onset Bipolar Disorder
        Correlates of under-diagnosis of Bipolar Disor-     Dr A Kaladjian (Fr)
        ders
        Prof E Karam (Lb)


        Plenary 4: Pathophysiology of psychosis and         Plenary 5: How much bipolar schizoaffective
        novel approaches to treatment                       disorder is?
18.15   Chair:     Dr J Cookson (UK)                        Chair:      Prof E Vieta (Es)
        Speaker:   Prof A Grace (US)                        Speaker:    Dr A Murru (Es)



18.45   Evening Lecture: Tackling stigma through theatre - “That’s Just Crazy Talk” by Victoria Maxwell
        Speaker:   Prof Erin Michalak (Ca)

19.30   CLOSE Day 1

20.30   Closed Committee Meeting & Dinner



 A Cortex Congress Conference                   PROGRAMME CO-CHAIRS
The 12th International Review of
                                                                             Bipolar Disorders
                                                                               21 - 23 May 2012 Nice, France
                                                                                               www.irbd.org


Day 2 - Tuesday 22 May 2012
09.00   European Bipolar Forum II: Bipolar Spectrum in special conditions
        Chairs:   Prof L Dell’Osso (I)/Prof H Akiskal (US)

        Sub-threshold Bipolar and reaction to stress and grief
        Prof L Dell’Osso (I)

        Affective temperaments and alcoholism
        Prof A Erfurth (At)

        Criminal conviction, impulsivity and course of illness in Bipolar Disorder
        Prof A Swann (US)

10.10   Science Update 3: Risk and Bipolar Disorder         Interactive 5: Bipolar Breakthrough: “BP-II B”
        Chair:    Prof L Dell’Osso (I)                      Chair:       Prof A Erfurth (At)
        Speaker:  Prof J Scott (UK)                         Speaker:     Dr R Fieve (US)

10.30   Refreshments

11.00   Debate Forum: Lithium Use for Bipolar Disorder - does the LiTMUS trial change anything?
        Chair: Prof A Young (UK)

        Speaker For: Dr P Grof (Ca)               Speaker Against: Dr R Fieve (US)


11.45   Lundbeck-sponsored Symposium
        Bipolar I disorder: Early and accurate diagnosis and treatment
        Chair: Allan Young (UK)

        Clinically relevant subtypes of Mania
        Giulio Perugi (I)

        Taking a broader view: New perspectives on the functional outcome
        Lars Häggström (Se)

        Asenapine, a multifunctional antipsychotic. From pharmacology to clinical benefits
        Eduard Vieta (Es)




13.15   Lunch




                                                                                                     Cont../...



 A Cortex Congress Conference                   PROGRAMME CO-CHAIRS
The 12th International Review of
                                                                                 Bipolar Disorders
                                                                                     21 - 23 May 2012 Nice, France
                                                                                                     www.irbd.org


Day 2 Cont../...
14.15   Plenary 6: Functional Remediation of Bipolar          Oral Platform Session I
        Disorder                                              Temperaments as mediators of suicide risk, hopelessness
        Chair:      Prof E Vieta (Es)                         and psychopathology in bipolar disorders
        Speaker:    Dr A Martinez-Aran (Es)                   Maurizio Pompili

                                                              The association between impulsivity and behaviour in indi-
                                                              viduals who screen positive on the Mood Disorders Ques-
                                                              tionnaire
                                                              Burden, J. Corcoran, R. Morris, R.

                                                              Objective versus Self-Report Measures of Impulsivity and
                                                              History of Suicide Attempt in Youth with Bipolar Disorder
                                                              Sally M. Weinstein, Ph.D., Woo-Young Ahn, B.S., Amy E. West,
                                                              Ph.D., and Mani Pavuluri, M.D., Ph.D.



14.45   Bipolar disorder understanding: bridging evidence-based medicine and daily practice
        Chairman: Prof Jean Michel Azorin (Fr)

        Wave BD : a 360 degree real world evidence bipolar disorder perspective
        Prof Eduard Vieta (Es)

        Bipolar depressive polarity care: the challenge of translating EBM in clinical practice
        Prof Philip Gorwood (Fr)




15.45   Comfort Break

16.15   Plenary 7: A 3-year, open label study of adjunc-      Oral Platform Session II
        tive Memantine in Treatment-resistant Bipolar
                                                              Can sophisiticated methods of evidence synthesis offer bet-
        Disorder                                              ter clinical decisions for treatment of bipolar mania?
        Chair:      Prof M Pompili (I)                        Aysegul Yildiz, Eduard Vieta, Mateusz Nikodem, Christoph U.
        Speaker:    Prof G Serra (I)                          Correll, Ross J Baldessarini

                                                              Deterministic dynamics of daily mood over 5 years in a pa-
                                                              tient with affective disorder
                                                              João Guilherme Ribeiro, Carlos Lourenço

16.45   Plenary 8: Mixed states: diagnostic and thera-        Creativity and Bipolar Disorder: Family Study of 300,000 Pa-
        peutic implications                                   tients
        Chair:      Prof E Vieta (Es)                         Mikael Landen
        Speaker:    Prof I Pacchiarotti (Es)                  Prevention of Postpartum Psychosis in Women at High Risk
                                                              Veerle Bergink, Paul F. Bouvy, Jeroen S.P.Vervoort, Kathelijne
                                                              M. Koorengevel, Eric A.P. Steegers, Steven A. Kushner

                                                              Cognitive inhibition and affective priming effect in Major
                                                              Depressive Disorder
                                                              B Gohier, D Denes, M Briere, CR Mesu, G Fournis, SA Surgu-
                                                              ladze, D le Gall, JB Garre

                                                              Mood Variability in Adult Women
                                                              Sarah Romans, David Kreindler, MD; Eriola Asllani MSc., Gillian
                                                              Einstein, PhD; Sheila Laredo, MD; Anthony Levitt, MD; Brenda
                                                              Toner, PhD; Donna Stewart, MD

                                                                                                                   Cont../...



 A Cortex Congress Conference                   PROGRAMME CO-CHAIRS
The 12th International Review of
                                                                          Bipolar Disorders
                                                                             21 - 23 May 2012 Nice, France
                                                                                             www.irbd.org


Day 2 Cont../...
17.15   Clinical Practice 1: Selecting best treatment for   Clinical Practice 2: Unmet Needs in Treating BP-
        the Bipolar Spectrum                                II Spectrum
        Chair:      Prof A Erfurth (At)                     Chair:      Dr E Hantouche (Fr)

        Changes in DSM-V for Bipolar Disorder type II       Think Effectively About Mood Swings (TEAMS):
        Prof O Pinto (Br)                                   the science and practice of novel CBT in BDs
                                                            Dr W Mansell (UK)
        Antidepressant resistant depression and suici-
        dal behaviour: the role of underlying bipolarity    Psychoeducation for cyclothymics
        Prof X Gonda (Hu)                                   Dr C Majdalani (Fr)

        Cognitive and temperamental correlates of lith-     Current role of psychodynamic treatment in Bi-
        ium response                                        polar Disorder
        Prof J Rybakowski (Pl)                              Dr R Bush (US)



18.15   Comfort Break

18.30   Evening Lecture: The Presentation of Bipolar Disorder in Historic and Contemporary Cinema
        Chair:     Dr E Hantouche (Fr)
        Speaker:   Prof D Wedding (US)

19.00   CLOSE Day 2

20.30   Gala Dinner and Presentation of EBF Lifetime Achievement Award




 A Cortex Congress Conference                   PROGRAMME CO-CHAIRS
The 12th International Review of
                                                                           Bipolar Disorders
                                                                              21 - 23 May 2012 Nice, France
                                                                                              www.irbd.org


Day 3 - Wednesday 23 May 2012
09.00   Plenary 9: Receptor targets for antidepressant therapy in bipolar disorder: an overview
        Chair:     Prof H Akiskal (US)
        Speaker:   Prof K Fountoulakis (Gr)

09.30   Plenary 10: The Potential Clinical Benefits of the Glutamate Neuromodulator N-acetylecysteine in Bi
                    polar Disorders and Associated Psychotic Conditions
        Chair:      Dr J Cookson (UK)
        Speaker:    Dr R McCarthy (US)


10.00   Interactive 6: Severe Bipolar Disorder - Pathol-    Interactive 7: Early Manifestations of Bipolarity:
        ogy and Sequelae                                    From Prodromes to Real Risk
        Chair:    Prof Z Rihmer (Hu)                        Chair:       Prof G Faedda (US)

        Suicide and Bipolar Disorder                        Paediatric Bipolar Disorder: an update
        Prof P Courtet (Fr)                                 Prof B Birmaher (US)

        Smoking, suicide and BP-II                          Early interventions in Bipolar Disorder
        Prof Z Rihmer (Hu)                                  Prof P Conus (Ch)

        The severe part of BP-II Spectrum                   Advances in assessment: Fast and Frugal meth-
        Dr J Deltito (US)                                   ods of detection without over diagnosis
                                                            Prof E Youngstrom (US)


11.30   Refreshments

12.00   Round table: Clinical Neurobiology of Bipolar Disorder
        Chair:     Prof K Fountoulakis (Gr)

        Relationship of body mass index, symptoms and cognition in mood disorders and schizophrenia
        Dr M Siamouli (Gr)

        Neurobiology of disability in bipolar disorder
        Dr M Mageiria (Gr)

        Bipolar disorder in the frame of dementia
        Dr D Kontis (Gr)

        Dopamine pathways in Bipolar disorder and Schizophrenia
        Dr E Tsapakis (Gr)

13.30   Conference Closing Address and Close




 A Cortex Congress Conference                    PROGRAMME CO-CHAIRS

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Programa Científico IRBD 2012

  • 1. The 12th International Review of Bipolar Disorders 21 - 23 May 2012 Nice, France www.irbd.org Day 1 - Monday 21 May 2012 - Proposed Programme 08.30 Registration/POSTER SET UP 09.00 IRBD 2012 Welcome and Introduction President: Prof J M Azorin (Fr) Chairman: Dr E Hantouche (Fr) Local committee: Prof J Allilaire (Fr), Prof D Pringuey (Fr), Dr P Robert (Fr) 09.15 Opening Plenary : The Future of Bipolar Spectrum Chair: Dr E Hantouche (Fr) Speaker: Prof H Akiskal (US) 09.45 Plenary 1: Bipolar Spectrum from Bridge Study and International Studies Chair: Prof A Young (UK) Speaker: Prof J Angst (Ch) 10.15 Coffee 10.45 European Bipolar Forum I: New Insights in Soft Bipolarity and Emotion Regulation Chairs: Prof J M Azorin (Fr) Validating cyclothymia in youth Prof E Youngstrom (US) / Dr A Van Meter (US) Intra-bipolar dichotomy: specificity of cyclothymia Dr E Hantouche (Fr) The affective and emotional composite temperament model and scale (AFECTS): utility for the evalua- tion and treatment of mood disorders Dr D Lara (Br) Temperaments across the spectra of mood disorders Prof J Angst (Ch) 12.45 Lunch POSTER VIEWING 13.45 Plenary 2: Stress and Bipolar Disorder Chair: Prof A Swann (US) Speaker: Prof A Young (UK) 14.15 Plenary 3: Subsyndromal Bipolar in the New Nosology Chair: Prof E Karam (Lb) Speaker: Prof A Okasha (Eg) Cont../... A Cortex Congress Conference PROGRAMME CO-CHAIRS
  • 2. The 12th International Review of Bipolar Disorders 21 - 23 May 2012 Nice, France www.irbd.org Day 1 Cont../... 14.45 Science Update 1: Bipolar Disorders: Poised for Interactive 1: Mania Phenotypes discovery? Chair: Prof D Pringuey (Fr) Chair: Prof J Allilaire (Fr) Mania phenotypes: findings from cluster analy- Addressing the likelihood to express clinical ses symptoms from a genetic tendency Prof J Azorin (Fr) Prof J Kelsoe (US) Hyperthymic vs clyclothymic BP-I disorder New perspectives from research to care and pre- Prof G Perugi (I) vention Prof M Leboyer (Fr) 15.45 Interactive 2: Management of difficult cases in Science Update 2: French Networks: Research Bipolar Disorder on Affective Disorders Chair: Prof F Bellivier (Fr) Mania in neuropsychiatric disorders. Focus in post-stroke mania French Expert Centre Network: first data Prof M L Figueira (P) Prof C Henry (Fr) Mania Dr J Cookson (UK) Functional brain imaging of unipolar and bipolar depression: differences and similarities ADHD/bipolar patients; distinctions and similari- Prof Fossatti (Fr) ties Dr V Syrstad/Dr K Odegaard (No) Comorbid addiction in Bipolar Disorder: results Postpartum Depression from the French Expert Centre Network Dr J Masmoudi (Fr) Prof F Bellivier (Fr) 16.45 Refreshments 17.15 Interactive 3: Assessment of Hypomania: Interactive 4: Geriatric Bipolarity Methodological Issues Chairs: Prof J M Azorin (Fr)/Dr P H Robert (Fr) Chair: Prof E Karam (Lb) Introducing “BP-VI” within the Bipolar Spectrum BP-II recognition in primary care Dr D Lara (Fr) Prof Z Rihmer (Hu) Treating late onset Bipolar Disorder Correlates of under-diagnosis of Bipolar Disor- Dr A Kaladjian (Fr) ders Prof E Karam (Lb) Plenary 4: Pathophysiology of psychosis and Plenary 5: How much bipolar schizoaffective novel approaches to treatment disorder is? 18.15 Chair: Dr J Cookson (UK) Chair: Prof E Vieta (Es) Speaker: Prof A Grace (US) Speaker: Dr A Murru (Es) 18.45 Evening Lecture: Tackling stigma through theatre - “That’s Just Crazy Talk” by Victoria Maxwell Speaker: Prof Erin Michalak (Ca) 19.30 CLOSE Day 1 20.30 Closed Committee Meeting & Dinner A Cortex Congress Conference PROGRAMME CO-CHAIRS
  • 3. The 12th International Review of Bipolar Disorders 21 - 23 May 2012 Nice, France www.irbd.org Day 2 - Tuesday 22 May 2012 09.00 European Bipolar Forum II: Bipolar Spectrum in special conditions Chairs: Prof L Dell’Osso (I)/Prof H Akiskal (US) Sub-threshold Bipolar and reaction to stress and grief Prof L Dell’Osso (I) Affective temperaments and alcoholism Prof A Erfurth (At) Criminal conviction, impulsivity and course of illness in Bipolar Disorder Prof A Swann (US) 10.10 Science Update 3: Risk and Bipolar Disorder Interactive 5: Bipolar Breakthrough: “BP-II B” Chair: Prof L Dell’Osso (I) Chair: Prof A Erfurth (At) Speaker: Prof J Scott (UK) Speaker: Dr R Fieve (US) 10.30 Refreshments 11.00 Debate Forum: Lithium Use for Bipolar Disorder - does the LiTMUS trial change anything? Chair: Prof A Young (UK) Speaker For: Dr P Grof (Ca) Speaker Against: Dr R Fieve (US) 11.45 Lundbeck-sponsored Symposium Bipolar I disorder: Early and accurate diagnosis and treatment Chair: Allan Young (UK) Clinically relevant subtypes of Mania Giulio Perugi (I) Taking a broader view: New perspectives on the functional outcome Lars Häggström (Se) Asenapine, a multifunctional antipsychotic. From pharmacology to clinical benefits Eduard Vieta (Es) 13.15 Lunch Cont../... A Cortex Congress Conference PROGRAMME CO-CHAIRS
  • 4. The 12th International Review of Bipolar Disorders 21 - 23 May 2012 Nice, France www.irbd.org Day 2 Cont../... 14.15 Plenary 6: Functional Remediation of Bipolar Oral Platform Session I Disorder Temperaments as mediators of suicide risk, hopelessness Chair: Prof E Vieta (Es) and psychopathology in bipolar disorders Speaker: Dr A Martinez-Aran (Es) Maurizio Pompili The association between impulsivity and behaviour in indi- viduals who screen positive on the Mood Disorders Ques- tionnaire Burden, J. Corcoran, R. Morris, R. Objective versus Self-Report Measures of Impulsivity and History of Suicide Attempt in Youth with Bipolar Disorder Sally M. Weinstein, Ph.D., Woo-Young Ahn, B.S., Amy E. West, Ph.D., and Mani Pavuluri, M.D., Ph.D. 14.45 Bipolar disorder understanding: bridging evidence-based medicine and daily practice Chairman: Prof Jean Michel Azorin (Fr) Wave BD : a 360 degree real world evidence bipolar disorder perspective Prof Eduard Vieta (Es) Bipolar depressive polarity care: the challenge of translating EBM in clinical practice Prof Philip Gorwood (Fr) 15.45 Comfort Break 16.15 Plenary 7: A 3-year, open label study of adjunc- Oral Platform Session II tive Memantine in Treatment-resistant Bipolar Can sophisiticated methods of evidence synthesis offer bet- Disorder ter clinical decisions for treatment of bipolar mania? Chair: Prof M Pompili (I) Aysegul Yildiz, Eduard Vieta, Mateusz Nikodem, Christoph U. Speaker: Prof G Serra (I) Correll, Ross J Baldessarini Deterministic dynamics of daily mood over 5 years in a pa- tient with affective disorder João Guilherme Ribeiro, Carlos Lourenço 16.45 Plenary 8: Mixed states: diagnostic and thera- Creativity and Bipolar Disorder: Family Study of 300,000 Pa- peutic implications tients Chair: Prof E Vieta (Es) Mikael Landen Speaker: Prof I Pacchiarotti (Es) Prevention of Postpartum Psychosis in Women at High Risk Veerle Bergink, Paul F. Bouvy, Jeroen S.P.Vervoort, Kathelijne M. Koorengevel, Eric A.P. Steegers, Steven A. Kushner Cognitive inhibition and affective priming effect in Major Depressive Disorder B Gohier, D Denes, M Briere, CR Mesu, G Fournis, SA Surgu- ladze, D le Gall, JB Garre Mood Variability in Adult Women Sarah Romans, David Kreindler, MD; Eriola Asllani MSc., Gillian Einstein, PhD; Sheila Laredo, MD; Anthony Levitt, MD; Brenda Toner, PhD; Donna Stewart, MD Cont../... A Cortex Congress Conference PROGRAMME CO-CHAIRS
  • 5. The 12th International Review of Bipolar Disorders 21 - 23 May 2012 Nice, France www.irbd.org Day 2 Cont../... 17.15 Clinical Practice 1: Selecting best treatment for Clinical Practice 2: Unmet Needs in Treating BP- the Bipolar Spectrum II Spectrum Chair: Prof A Erfurth (At) Chair: Dr E Hantouche (Fr) Changes in DSM-V for Bipolar Disorder type II Think Effectively About Mood Swings (TEAMS): Prof O Pinto (Br) the science and practice of novel CBT in BDs Dr W Mansell (UK) Antidepressant resistant depression and suici- dal behaviour: the role of underlying bipolarity Psychoeducation for cyclothymics Prof X Gonda (Hu) Dr C Majdalani (Fr) Cognitive and temperamental correlates of lith- Current role of psychodynamic treatment in Bi- ium response polar Disorder Prof J Rybakowski (Pl) Dr R Bush (US) 18.15 Comfort Break 18.30 Evening Lecture: The Presentation of Bipolar Disorder in Historic and Contemporary Cinema Chair: Dr E Hantouche (Fr) Speaker: Prof D Wedding (US) 19.00 CLOSE Day 2 20.30 Gala Dinner and Presentation of EBF Lifetime Achievement Award A Cortex Congress Conference PROGRAMME CO-CHAIRS
  • 6. The 12th International Review of Bipolar Disorders 21 - 23 May 2012 Nice, France www.irbd.org Day 3 - Wednesday 23 May 2012 09.00 Plenary 9: Receptor targets for antidepressant therapy in bipolar disorder: an overview Chair: Prof H Akiskal (US) Speaker: Prof K Fountoulakis (Gr) 09.30 Plenary 10: The Potential Clinical Benefits of the Glutamate Neuromodulator N-acetylecysteine in Bi polar Disorders and Associated Psychotic Conditions Chair: Dr J Cookson (UK) Speaker: Dr R McCarthy (US) 10.00 Interactive 6: Severe Bipolar Disorder - Pathol- Interactive 7: Early Manifestations of Bipolarity: ogy and Sequelae From Prodromes to Real Risk Chair: Prof Z Rihmer (Hu) Chair: Prof G Faedda (US) Suicide and Bipolar Disorder Paediatric Bipolar Disorder: an update Prof P Courtet (Fr) Prof B Birmaher (US) Smoking, suicide and BP-II Early interventions in Bipolar Disorder Prof Z Rihmer (Hu) Prof P Conus (Ch) The severe part of BP-II Spectrum Advances in assessment: Fast and Frugal meth- Dr J Deltito (US) ods of detection without over diagnosis Prof E Youngstrom (US) 11.30 Refreshments 12.00 Round table: Clinical Neurobiology of Bipolar Disorder Chair: Prof K Fountoulakis (Gr) Relationship of body mass index, symptoms and cognition in mood disorders and schizophrenia Dr M Siamouli (Gr) Neurobiology of disability in bipolar disorder Dr M Mageiria (Gr) Bipolar disorder in the frame of dementia Dr D Kontis (Gr) Dopamine pathways in Bipolar disorder and Schizophrenia Dr E Tsapakis (Gr) 13.30 Conference Closing Address and Close A Cortex Congress Conference PROGRAMME CO-CHAIRS