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Therapeutics in Dentistry
     (General Principles)


       Iyad Abou Rabii
     DDS,OMFS,Mres,PhD
Pharmacology Basics

• Indications
  – The reasons for administering a
    medication or performing a treatment
• Contra-indications
  – A factor that prevents the use of a
    medication or treatment (eg. Allergies)


                                              2
Pharmacology Basics
• Dose
  – The amount of a drug to be administered
    at one time
• Mechanism of Action
  – How a drug works



                                              3
Pharmacology Basics

• Effects
  – The desired result of administration of a
    medication
• Side Effects
  – Effects that are not desired and that occur
    in addition to the desired therapeutic
    effects

                                                  4
Medication Names

• Chemical Name
  – describes the drug’s chemical structure
• Generic Name
  – reflects the chemical name, but in shorter
    form



                                                 5
Medication Names
• Trade Name
  – the name the manufacturer uses to market
    the drug
• Official Name
  – the name used in the Pharmocopoeia



                                               6
Routes

• Enteral tract routes
• Parenteral routes
Comparison of Enteral vs.
   Parenteral Routes
Enteral Routes
•   Oral (PO)
•   Orogastric/nasogastric (OG/NG)
•   Sublingual (SL)
•   Buccal
•   Rectal (PR)
Parenteral Routes
• Topical              • Sublingual
• Intradermal            injection
• Intranasal           • Intracardiac (IC)
• Subcutaneous         • Intraosseous
  (SC)                 • Inhalational
• Intramuscular (IM)   • Umbilical
• Intravenous (IV)     • Vaginal
• Endotracheal (ET)    • Pulpal
No single method of drug
administration is ideal for all
drugs in all circumstances
The Medication Order
         (Prescription)
•   Medication desired
•   Dose desired
•   Administration route
•   Administration rate
Before any Drug
prescription
• Discuss with patient the possible
  consequences (god and bad)
• Prescribe drugs you know
• Keep updated
  (BNF, Vidal…others)
• Dose: consider
  age, physiology, and pathology
• Drug interactions
Prescribing
• The Dentist is legally responsible for
  the signed prescription
• Prescription should be indelible, dated,
  with full name and address of the
  patient
• Age of patient should be mentioned
  when under 12.
• Use generic drugs when possible
Prescribing

• Don`t use abbreviations for the drug
  names.
• Define the quantity supplied
• Directions should be in English with no
  use of the abbreviations
Prescribing

• When writing the dose
  – Quantities of one gram is wrriten (1 g)
  – Less than 1 g is written in milligrams (500
    mg)
  – Less than l mg should be written in
    microgram 100 microgram (not 0.1 mg)
  – Nanogram and microgram should not be
    abbreviated
Clark’s Rule

Clark's Rule

Divide the child’s weight (in pounds) by 150 to get the approximate
   fraction of the adult dose to give to the child.
               Example: For a 50 pound child give 50/150 (or 1/3) of the
               adult dose. Therefore, if the adult dose is 30 drops taken 3
               times per day, the child’s dose will be 10 drops taken 3
               times per day
               (not 30 drops taken 1 time per day).




•
Essential Components of
              Prescriptions

All written prescriptions should contain:
1) Patient's full name and address
2) Prescriber's full name, address, telephone number,
3) Date of issuance
4) Signature of prescriber
5) Drug name, dose, dosage form, amount
6) Directions for use
7) Refill instructions
Essential Components of
     Prescriptions
Latin abbreviations

•   Rx : abbreviation of the Latin word "recipe” x as a
    substitute period.

•   # ac (ante cibum)

     •   means "before meals"

•   # bid (bis in die) means

     •   "twice a day"
Latin abbreviations

•   # po (per os)

     •   means "by mouth"

•   # pc (post cibum) means

     •   "after meals"

•   # prn (pro re nata)

     •   means "as needed"
Latin abbreviations
•   # q 3 h (quaque 3 hora)

     •   means "every 3 hours"

•   # qd (quaque die)

     •   means "every day"

•   # qid (quater in die) means

     •   "4 times a day"

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Therapeutics in dentistry(general principles)

  • 1. Therapeutics in Dentistry (General Principles) Iyad Abou Rabii DDS,OMFS,Mres,PhD
  • 2. Pharmacology Basics • Indications – The reasons for administering a medication or performing a treatment • Contra-indications – A factor that prevents the use of a medication or treatment (eg. Allergies) 2
  • 3. Pharmacology Basics • Dose – The amount of a drug to be administered at one time • Mechanism of Action – How a drug works 3
  • 4. Pharmacology Basics • Effects – The desired result of administration of a medication • Side Effects – Effects that are not desired and that occur in addition to the desired therapeutic effects 4
  • 5. Medication Names • Chemical Name – describes the drug’s chemical structure • Generic Name – reflects the chemical name, but in shorter form 5
  • 6. Medication Names • Trade Name – the name the manufacturer uses to market the drug • Official Name – the name used in the Pharmocopoeia 6
  • 7. Routes • Enteral tract routes • Parenteral routes
  • 8. Comparison of Enteral vs. Parenteral Routes
  • 9. Enteral Routes • Oral (PO) • Orogastric/nasogastric (OG/NG) • Sublingual (SL) • Buccal • Rectal (PR)
  • 10. Parenteral Routes • Topical • Sublingual • Intradermal injection • Intranasal • Intracardiac (IC) • Subcutaneous • Intraosseous (SC) • Inhalational • Intramuscular (IM) • Umbilical • Intravenous (IV) • Vaginal • Endotracheal (ET) • Pulpal
  • 11. No single method of drug administration is ideal for all drugs in all circumstances
  • 12. The Medication Order (Prescription) • Medication desired • Dose desired • Administration route • Administration rate
  • 13. Before any Drug prescription • Discuss with patient the possible consequences (god and bad) • Prescribe drugs you know • Keep updated (BNF, Vidal…others) • Dose: consider age, physiology, and pathology • Drug interactions
  • 14. Prescribing • The Dentist is legally responsible for the signed prescription • Prescription should be indelible, dated, with full name and address of the patient • Age of patient should be mentioned when under 12. • Use generic drugs when possible
  • 15. Prescribing • Don`t use abbreviations for the drug names. • Define the quantity supplied • Directions should be in English with no use of the abbreviations
  • 16. Prescribing • When writing the dose – Quantities of one gram is wrriten (1 g) – Less than 1 g is written in milligrams (500 mg) – Less than l mg should be written in microgram 100 microgram (not 0.1 mg) – Nanogram and microgram should not be abbreviated
  • 17. Clark’s Rule Clark's Rule Divide the child’s weight (in pounds) by 150 to get the approximate fraction of the adult dose to give to the child. Example: For a 50 pound child give 50/150 (or 1/3) of the adult dose. Therefore, if the adult dose is 30 drops taken 3 times per day, the child’s dose will be 10 drops taken 3 times per day (not 30 drops taken 1 time per day). •
  • 18. Essential Components of Prescriptions All written prescriptions should contain: 1) Patient's full name and address 2) Prescriber's full name, address, telephone number, 3) Date of issuance 4) Signature of prescriber 5) Drug name, dose, dosage form, amount 6) Directions for use 7) Refill instructions
  • 19. Essential Components of Prescriptions
  • 20. Latin abbreviations • Rx : abbreviation of the Latin word "recipe” x as a substitute period. • # ac (ante cibum) • means "before meals" • # bid (bis in die) means • "twice a day"
  • 21. Latin abbreviations • # po (per os) • means "by mouth" • # pc (post cibum) means • "after meals" • # prn (pro re nata) • means "as needed"
  • 22. Latin abbreviations • # q 3 h (quaque 3 hora) • means "every 3 hours" • # qd (quaque die) • means "every day" • # qid (quater in die) means • "4 times a day"