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Sukkin Pungchim, MD.
  Emergency Medicine Resident, PGY II
Elective Rotation in Emergency Radiology


                     Ann Emerg Med. 2011;58:315-322
• TBI is the leading cause of death and disability in children > 1 yr
• Cranial CT is diagnostic of choice in blunt head trauma
• Most children presenting to ED after minor head trauma do not
  require CT scanning, if done >90% Cranial CT shown normal
• Many children with minor head trauma are hospitalized for
  neurologic observation despite normal ED cranial CT
• Limited pediatric data in necessity of hospitalization
• Identify the frequency of children with minor blunt head
  injury and normal initial CT results have either traumatic
  findings in a subsequent neuroimaging or experience
  neurologic deterioration resulting in the need for
  neurosurgery
• Study design
  – Prospective, multicenter observational cohort study at 25 centers
    between 2004 and 2006
• Population
  – Children younger than 18 yr with blunt head trauma and initial GCS of 14
    or 15 who had normal cranial CT scan results during ED evaluation
• Data collecting and processing
  – Documentation of GCS/Vomiting/Isolated head trauma/Multisystem
  – Finalized report of Cranial CT or MRI
  – Patients D/C from ED followed by phone, mail, medical records review, ED
    CQI, trauma registry records, country morgue documentation
• Outcome measure
  – Traumatic findings on subsequent CT or MRI and
  – Neurosurgical intervention (eg, craniotomy, ventricular drainage)
• Primary data analysis
  – Determined NPV for negative (normal) ED CT scan result for identifying
    those patients not needing a neurosurgical intervention
  – SAS statistical software (version 9.2)
• Sensitivity analyses
  – Worse-case scenario in those patients D/C from ED but failed to follow-up
93%              7%




17%        83%   39%       61%



6%         2%    6%        2%
• Negative predictive value for neurosurgical intervention of a
  normal ED CT scan result in a patient with an initial ED GCS 15
  was 100% (95% CI 99.97% to 100%)
• Negative predictive value for neurosurgical intervention of a
  normal ED CT scan result in patients with initial GCS scores of 14
  was 100% (95% CI 99.6% to 100%)
• Sensitivity analyses : Worse case scenario
•  proportion of patients with GCS 15 but lost follow-up could be
  another 11 patients
•  proportion of patients with GCS 14 but lost follow-up could be
  another 1 patients
• If this were true : The proportion would increase only from
  21/13,543(0.16%) to 33/13,543(0.24%)
   – 5% of the patients who were lost to telephone follow-up would need
     to have traumatic findings on a subsequent CT or MRI (ie, 115 of the
     2,302 patients lost to telephone follow-up)
   – Highly unlikely, given that this far exceeds the proportion with
     subsequent traumatic findings on cranial imaging in those admitted
• Not all patients enrolled into the primary study underwent CT
• Patients who did not undergo repeat imaging would have had
  traumatic findings had they received imaging a second time
• Lost follow-up patients might have traumatic findings identified
  on CT or MRI at another hospital
• Exact reasons/indications for hospitalization after normal
  cranial CT not specifically described
• Real-time CT interpretations in many centers could be from
  radiology resident
• Not assess brain injury in terms of long term neurocognitive
  function
• Children with blunt head trauma and initial ED GCS scores of 14 or
  15 and normal cranial CT scan results
   – Very low risk for subsequent traumatic findings on neuroimaging
   – Extremely low risk of needing neurosurgical intervention
• Routine hospitalization of children with minor head trauma after
  normal CT scan results for neurologic observation is generally
  unnecessary
• There remain indications for admitting children w/minor head injury
   – Multisystem trauma
   – Symptomatic patients require IV fluids and neurologic observation
     (18% of hospitalized patient had vomiting documented )
   – Others : Social, concern for other injuries
• Many medical center across US, even pediatric centers simply
  admit for neurologic observation
• Potential to reduce medical costs, reduce hospital crowding,
  provide more optimal care
• Hospitalized patients were more likely to undergo subsequent
  neuroimaging because of ease and accessibility
• EP were likely admitting patients with more symptomatic and
  more severe head trauma despite normal cranial CT results
• Several patients with subsequent traumatic findings found were
  never hospitalized
Do Children With Blunt Head Trauma and Normal Cranial Computed Tomography Scan Results Require Hospitalization for Neurologic Observation?

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Do Children With Blunt Head Trauma and Normal Cranial Computed Tomography Scan Results Require Hospitalization for Neurologic Observation?

  • 1. Sukkin Pungchim, MD. Emergency Medicine Resident, PGY II Elective Rotation in Emergency Radiology Ann Emerg Med. 2011;58:315-322
  • 2. • TBI is the leading cause of death and disability in children > 1 yr • Cranial CT is diagnostic of choice in blunt head trauma • Most children presenting to ED after minor head trauma do not require CT scanning, if done >90% Cranial CT shown normal • Many children with minor head trauma are hospitalized for neurologic observation despite normal ED cranial CT • Limited pediatric data in necessity of hospitalization
  • 3. • Identify the frequency of children with minor blunt head injury and normal initial CT results have either traumatic findings in a subsequent neuroimaging or experience neurologic deterioration resulting in the need for neurosurgery
  • 4. • Study design – Prospective, multicenter observational cohort study at 25 centers between 2004 and 2006 • Population – Children younger than 18 yr with blunt head trauma and initial GCS of 14 or 15 who had normal cranial CT scan results during ED evaluation • Data collecting and processing – Documentation of GCS/Vomiting/Isolated head trauma/Multisystem – Finalized report of Cranial CT or MRI – Patients D/C from ED followed by phone, mail, medical records review, ED CQI, trauma registry records, country morgue documentation
  • 5. • Outcome measure – Traumatic findings on subsequent CT or MRI and – Neurosurgical intervention (eg, craniotomy, ventricular drainage) • Primary data analysis – Determined NPV for negative (normal) ED CT scan result for identifying those patients not needing a neurosurgical intervention – SAS statistical software (version 9.2) • Sensitivity analyses – Worse-case scenario in those patients D/C from ED but failed to follow-up
  • 6. 93% 7% 17% 83% 39% 61% 6% 2% 6% 2%
  • 7. • Negative predictive value for neurosurgical intervention of a normal ED CT scan result in a patient with an initial ED GCS 15 was 100% (95% CI 99.97% to 100%) • Negative predictive value for neurosurgical intervention of a normal ED CT scan result in patients with initial GCS scores of 14 was 100% (95% CI 99.6% to 100%)
  • 8. • Sensitivity analyses : Worse case scenario •  proportion of patients with GCS 15 but lost follow-up could be another 11 patients •  proportion of patients with GCS 14 but lost follow-up could be another 1 patients • If this were true : The proportion would increase only from 21/13,543(0.16%) to 33/13,543(0.24%) – 5% of the patients who were lost to telephone follow-up would need to have traumatic findings on a subsequent CT or MRI (ie, 115 of the 2,302 patients lost to telephone follow-up) – Highly unlikely, given that this far exceeds the proportion with subsequent traumatic findings on cranial imaging in those admitted
  • 9. • Not all patients enrolled into the primary study underwent CT • Patients who did not undergo repeat imaging would have had traumatic findings had they received imaging a second time • Lost follow-up patients might have traumatic findings identified on CT or MRI at another hospital • Exact reasons/indications for hospitalization after normal cranial CT not specifically described • Real-time CT interpretations in many centers could be from radiology resident • Not assess brain injury in terms of long term neurocognitive function
  • 10. • Children with blunt head trauma and initial ED GCS scores of 14 or 15 and normal cranial CT scan results – Very low risk for subsequent traumatic findings on neuroimaging – Extremely low risk of needing neurosurgical intervention • Routine hospitalization of children with minor head trauma after normal CT scan results for neurologic observation is generally unnecessary • There remain indications for admitting children w/minor head injury – Multisystem trauma – Symptomatic patients require IV fluids and neurologic observation (18% of hospitalized patient had vomiting documented ) – Others : Social, concern for other injuries
  • 11. • Many medical center across US, even pediatric centers simply admit for neurologic observation • Potential to reduce medical costs, reduce hospital crowding, provide more optimal care • Hospitalized patients were more likely to undergo subsequent neuroimaging because of ease and accessibility • EP were likely admitting patients with more symptomatic and more severe head trauma despite normal cranial CT results • Several patients with subsequent traumatic findings found were never hospitalized