1. Clinico-Economical Impact of HTA Implementation on chest pain diagnostic Marker Dott. Antonella Pugliese U.O. Education and Clinical Governance S.Camillo-Forlanini Hospital, Rome, Italy

2. WHY AN HTA ON CHEST PAIN DIAGNOSTIC MARKERS PRESCRIPTION? TECHNOLOGY IMPROVEMENT GUIDELINE MODIFICATION MAIN DIAGNOSTIC MARKERS OF CHEST PAIN: TROPONIN I and T CK-MB MYOGLOBIN

3. METHODOLOGY OF TECHNOLOGY STUDY Technologies Yes, Itshouldbeused No Indication X3= note Clinical presentations

4. S. Camillo- Forlanini U.O. Formazione e Governo Clinico METHODOLOGY OF TECHNOLOGY STUDY

5. INTERVENTION OUTCOME GRAPHICS

6. CLINICAL IMPACT VERIFICATION THROUGH STATISTICAL ANALYSIS CONFIDENCE INTERVAL CONTAINS NUMBER ONE NULL HYPOTESIS IS CONFIRMED THERE IS NOT ANY DIFFERENCE BETWEEN BEFORE AND AFTER THE INTERVENTION

7. ECONOMICAL ANALYSIS

8. S. Camillo- Forlanini U.O. Formazione e Governo Clinico APPROPRIATENESS AND ECONOMICAL IMPACT We started from an average of about 1100 myoglobin / month / First Aidtests.The intervention led to an inappropriateness reduction of 96.78%.

9. Thank you for your attention! Contacts: htacamp@gmail.com