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1 SSaammppllee,, SSaarraahh Communication Studies 105 (Day and Time) SAMPLE OUTLINE DESCRIPTIVE SPEECH Amyotrophic Lateral Sclerosis INTRODUCTION: Attention Getter: When my grandmother passed away six years ago on my fourteenth birthday, I was determined to understand exactly what was responsible for taking her young, exuberant life away from her. The disease responsible for this was Amyotrophic Lateral Sclerosis, also known as ALS or Lou Gehrig's disease. Named after baseball great Lou Gehrig, who was diagnosed with the disease in 1939, ALS is a disorder that is considered rare, even though more and more occurrences are being reported every year. ALS is known for its inconsistency and the harsh toll that it takes on the body, and is feared by both patients and medical professionals alike. Central Idea (Thesis): Amyotrophic Lateral Sclerosis is a rare but extremely devastating disease that affects every patient differently. Credibility Statement: I witnessed my grandma's deterioration from this disease, and can tell you first hand that ALS is a horrible disease that does not have a single definitive aspect. Preview: Today I would like to tell you what ALS is, the various symptoms associated with it, the progression of the disease, and possible treatment options. BODY: I. ALS is a disease of the nervous system that gradually destroys voluntary motor neurons, the neurons responsible for contracting skeletal muscles, eventually causing complete muscle atrophy. A. ALS affects two major parts of the brain, including the cerebrum and the brain stem. 1. ALS attacks motor neurons in these areas, causing the patient to lose control of different muscles one group at a time. 2. Mary Dodson Wade, author of the book ALS-Lou Gehrig's Disease, explains that the disease progresses and eventually leaves the body unable to function. (Wade 42). a. This is due to the fact that there are no motor neurons to send messages between the brain, spinal cord, and the muscles. 2 b. However, sensory neurons are left unaffected, meaning that the patient is completely alert when his or her body is ceasing to function. B. According to Wade, ALS occurs most often in persons between the ages of forty and seventy. (Wade, 47). 1. The average age when disease becomes apparent is 55 years old. 2. There are some cases of patients in their early twenties, and also of people in their eighties. C. There are three different types of ALS. 1. Sporadic ALS, which occurs randomly, is the most common form, comprising 90% of all cases. 2. Familial ALS, which is inherited, is not nearly as common, making up 5- 10% of all cases. 3. Guamanian ALS, which is found in small places of the Pacific (Guam), is very rare. (Internal Summary/Preview: Now that I have defined ALS, I would like to describe some of the symptoms that can be associated with the disease.) II. The symptoms that a ...
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These are simplified slides discussing the regulation of cardiac output and venous return. Learning objectives: 1. Comprehend the determinants of cardiac output and factors affecting cardiac output 2. Comprehend the factors affecting stroke volume and heart rate and total peripheral resistance 3. Identify the factors regulating venous return 4. Discuss the causes of high and low output cardiac failure 5. Enlist the functions of veins and recognise the significance of venous reservoirs Study Resources: 1. Chapter 20, Guyton and Hall Textbook of Medical Physiology, 14th edition 2. Chapter 30 and 32, Ganong’s Review of Medical Physiology, 26th edition 3. Chapter 10, Human Physiology by Lauralee Sherwood, 9th edition 4. Physiology, Cardiac Output - StatPearls https://www.ncbi.nlm.nih.gov/books/NBK470455/
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