Anatomy & physiology of neuromuscular junction & monitoring

Presented by Dr.Rashmi.G Chairperson Dr.M.Jajoor MD,DA PROFESSOR & HOD

INTRODUCTION ,[object Object],[object Object],[object Object]

PHYSIOLOGY OF NEUROMUSCULAR TRANSMISSION ,[object Object],[object Object],[object Object]

PARTS OF NMJ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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PREJUNCTIONAL RECEPTORS ,[object Object],[object Object],[object Object]

EXTRAJUNCTIONAL RECEPTOR ,[object Object],[object Object],[object Object]

CONTRACTILE APPARATUS ,[object Object],[object Object]

Ach (Synthesis, storage, release) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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STRUCTURE OF NA CHANNEL ,[object Object],[object Object],[object Object],[object Object],[object Object]

POSSIBLE CONFIGURATION OF Na CHANNELS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

ROLE OF CALCIUM ,[object Object],[object Object],[object Object]

ACETYLCHOLINESTERASE ,[object Object],[object Object]

PHYSICAL CHANNEL BLOCKADE ,[object Object],[object Object],[object Object],[object Object]

OPEN CHANNEL BLOCK ,[object Object],[object Object],[object Object]

CLOSED CHANNEL BLOCK ,[object Object],[object Object],[object Object],[object Object]

INTRODUCTION ,[object Object],[object Object],[object Object],[object Object],[object Object]

FEATURES OF NEUROSTIMULATION ,[object Object],[object Object],[object Object],[object Object]

ELECTRODES ,[object Object],[object Object]

ADVANTAGES OF TOF STIMULATION ,[object Object],[object Object]

TETANIC STIMULATION ,[object Object],[object Object]

DISADVANTAGES ,[object Object],[object Object]

DOUBLE BURST STIMULATION ,[object Object],[object Object],[object Object]

POST- TETANIC COUNT (PTC) ,[object Object],[object Object],[object Object],[object Object]

APPLICATION OF PTC ,[object Object],[object Object]

MONITORING SITES ,[object Object]

Relative sensitivities of muscle groups to nondepolarizing muscle relaxants MUSCLES SENSITIVITY Vocal cord Most Resistant Diaphragm Orbicularis oculi Abdominal rectus Adductor pollicis Masseter Pharyngeal Extraocular Most sensitive

ULNAR NERVE ,[object Object],[object Object],[object Object],[object Object]

NERVES OF THE FOOT ,[object Object],[object Object]

ASSESSMENT OF EVOKED RESPONSE TO NEUROMUSCULAR STIMULATION ,[object Object],[object Object],[object Object],[object Object],[object Object]

RECORDING DEVICES FOR MEASURING NEUROMUSCULAR FUNCTION ,[object Object],[object Object],[object Object]

ACCELEROMYOGRAPHY ,[object Object],[object Object],[object Object],[object Object]

CLINICAL APPLICATION ,[object Object],[object Object],[object Object],[object Object],[object Object]

WHICH PATIENT SHOULD BE MONITORED ,[object Object],[object Object],[object Object],[object Object]

LIMITATIONS OF NEUROMUSCULAR MONITORING ,[object Object],[object Object],[object Object]

REFERENCES: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Anatomy & physiology of neuromuscular junction & monitoring

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Anatomy & physiology of neuromuscular junction & monitoring