1. Synthetic Drugs of Abuse: ‘Spice,’ ‘K2’ and ‘Bath Salts’ Erik Gunderson, MD Assistant Professor Department of Psychiatry and Neurobehavioral Sciences and Department of Medicine Director, Clinical Pharmacological Research Unit University of Virginia April 14, 2011
27. Acknowledgement Laura Willing, BS Contact Information Erik Gunderson, MD 434-924-8013 office [email_address]
Editor's Notes
No disclosure
Potpouri, other brands
Also vaporization, many mix due to the poor taste, ads such as above look more like MJ than in reality Poorly labeled contents John Huffman compounds, Pfizer CP compound, 100s of others
Potency: tigher binding, full agonism: potentially greater harm?
Virtually nothing known about clinical effects (e.g., from human lab studies), few non-structured studies describe Also, MJ cas >60 cannabinoids may modulate delta-9 effects (e.g., cannabidiod) Survey data
Acute anxiety reactions, psychosis in biol vulnerable
Available in UK 2006-7 first mention Off the shelves 12/2010 before xmas still available INTERNET REG? CHANGE NAME? COMPOUND?
Anecdotally teen/young adult National Poison Data System (NPDS
Limited data on clinical effects, mostly non-scientific anecdote
MDMA comparison anecdotal, non-scietific data hence slang terminology
Also, few scientific data
Anecdotally teen/young adult National Poison Data System (NPDS