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Ashley Walker
 Biology 2401

                1
2
WHAT IS CROHN’S DISEASE ?
 A chronic inflammatory disease of the gastrointestinal
  tract. It primary causes ulceration in the large and
  small intestines.
 It usually affects the large and small intestines but can
  occur anywhere in the GI tract from the mouth to the
  anus.




                                                              3
NORMAL DIGESTIVE TRACT
 Organs of the digestive tract
  -Mouth
  -Esophagus
  -Stomach
  -Small intestine
  -Large intestine
  -Rectum
  -Anus




                                  4
Normal   Crohn’s
Colon    Colon




                   5
WHAT CAUSES CROHN’S DISEASE ?
  The cause of Crohn’s Disease is unknown
 Current Theories
  -Immune system acting on its self
  -Something in the environment
  -Genes




                                            6
WHO GET’S CROHN’S DISEASE?
 500 thousand Americans have Crohn’s
 20 to 25% have a blood relative with Crohn’s
 Most people are diagnosed between the ages of 15 and
    35, but can occur at any age
   Affects males and females equally
   Occurs in Caucasians more often than any other racial
    group.
   Found mainly in developed countries
   Smoking also increases risk

                                                            7
Symptoms
 Abdominal pain and cramping
 Diarrhea
 Fever
 Weight Loss
 Bloating
 Anal pain or drainage
 Rectal abscess
 Fissure



                                8
OTHER SYMPTOMS
           Symptoms outside the intestines
   Eyes (redness and itching)
   Mouth (sores)
   Joints ( swelling and pain)
   Skin ( bumps and other lesions)
   Bones (osteoporosis)
   Kidney (stones)
   Liver (hepatitis and cirrhosis) rare




                                             9
DIAGNOSIS
 Family and personal history
 Stool test
 Blood test
 Colonoscopy
 CAT Scans
 Barium X-rays



                                10
TREATMENT
                 Medications

   Anti-Inflammatory drugs
   Anti-diarrheal
   Immune suppressors
   Remicade
   Antibiotics




                               11
OTHER TREATMENTS
 Diet and Nutrition
   -Decrease in appetite
   -Poor absorption of nutrients
 Surgery
  -Two-thirds of patients will require surgery




                                                 12
QUESTIONS

 Can stress make Crohn’s Disease worse?


 Is pregnancy safe for women with Crohn’s Disease?


 Can Crohn’s cause cancer?




                                                      13
LIVING WITH CROHN’S
 Crohn’s Disease is not curable but it is treatable.


 Most people will have periods of remission


 It’s import to follow you doctors advice








                                                        14
FINDING A CURE
 Research


 Crohn’s and Colitis Foundation
  of America




                                   15
References Cited
About Crohn’s Disease, Crohn’s and Colitis Foundation of America. 2 April 2010. http://ccfa.org/info/about/crohns

Cocker, Joe. “You Can Leave Your Hat On,” Super Hits, SONEY&BMG

Crohn’s Disease, MedicineNet.com.: 2 April 2010 http: www.medicinenet.com/crohns_disease/article.htm

Crohn’s Disease, National Institute of Heath, National Digestive Disease Information Clearing House: 2 April 2010

  http://digestive.niddk,nih.gov/ddiseases/pub/crohns/

Crohn’s Info, Crohn’s Disease Info Center. Shafran Gastroenterology Center. 2 April

  2010http://shafran.net/crohn/cdinfo.htm

Living with Crohn’s, N.p. :Crohn's and Colitis Foundation, March 2007

Normal and Diseased Colons, Online Image, 2 April 2010

    http://sswahs.nse.gov.au/concord/gastr/BowelDisease/Crphn.html

    http://www.medikidz.com


                                                                                                                    16

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Crohns disease movie

  • 2. 2
  • 3. WHAT IS CROHN’S DISEASE ?  A chronic inflammatory disease of the gastrointestinal tract. It primary causes ulceration in the large and small intestines.  It usually affects the large and small intestines but can occur anywhere in the GI tract from the mouth to the anus. 3
  • 4. NORMAL DIGESTIVE TRACT  Organs of the digestive tract -Mouth -Esophagus -Stomach -Small intestine -Large intestine -Rectum -Anus 4
  • 5. Normal Crohn’s Colon Colon 5
  • 6. WHAT CAUSES CROHN’S DISEASE ? The cause of Crohn’s Disease is unknown  Current Theories -Immune system acting on its self -Something in the environment -Genes 6
  • 7. WHO GET’S CROHN’S DISEASE?  500 thousand Americans have Crohn’s  20 to 25% have a blood relative with Crohn’s  Most people are diagnosed between the ages of 15 and 35, but can occur at any age  Affects males and females equally  Occurs in Caucasians more often than any other racial group.  Found mainly in developed countries  Smoking also increases risk 7
  • 8. Symptoms  Abdominal pain and cramping  Diarrhea  Fever  Weight Loss  Bloating  Anal pain or drainage  Rectal abscess  Fissure 8
  • 9. OTHER SYMPTOMS Symptoms outside the intestines  Eyes (redness and itching)  Mouth (sores)  Joints ( swelling and pain)  Skin ( bumps and other lesions)  Bones (osteoporosis)  Kidney (stones)  Liver (hepatitis and cirrhosis) rare 9
  • 10. DIAGNOSIS  Family and personal history  Stool test  Blood test  Colonoscopy  CAT Scans  Barium X-rays 10
  • 11. TREATMENT Medications  Anti-Inflammatory drugs  Anti-diarrheal  Immune suppressors  Remicade  Antibiotics 11
  • 12. OTHER TREATMENTS  Diet and Nutrition -Decrease in appetite -Poor absorption of nutrients  Surgery -Two-thirds of patients will require surgery 12
  • 13. QUESTIONS  Can stress make Crohn’s Disease worse?  Is pregnancy safe for women with Crohn’s Disease?  Can Crohn’s cause cancer? 13
  • 14. LIVING WITH CROHN’S  Crohn’s Disease is not curable but it is treatable.  Most people will have periods of remission  It’s import to follow you doctors advice  14
  • 15. FINDING A CURE  Research  Crohn’s and Colitis Foundation of America 15
  • 16. References Cited About Crohn’s Disease, Crohn’s and Colitis Foundation of America. 2 April 2010. http://ccfa.org/info/about/crohns Cocker, Joe. “You Can Leave Your Hat On,” Super Hits, SONEY&BMG Crohn’s Disease, MedicineNet.com.: 2 April 2010 http: www.medicinenet.com/crohns_disease/article.htm Crohn’s Disease, National Institute of Heath, National Digestive Disease Information Clearing House: 2 April 2010 http://digestive.niddk,nih.gov/ddiseases/pub/crohns/ Crohn’s Info, Crohn’s Disease Info Center. Shafran Gastroenterology Center. 2 April 2010http://shafran.net/crohn/cdinfo.htm Living with Crohn’s, N.p. :Crohn's and Colitis Foundation, March 2007 Normal and Diseased Colons, Online Image, 2 April 2010 http://sswahs.nse.gov.au/concord/gastr/BowelDisease/Crphn.html http://www.medikidz.com 16