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CROWDSOURCING BIOCURATION WITH
      BIOLOGICAL GAMES
               Benjamin Good
        The Scripps Research Institute
                  @bgood
BIOCURATORS FACED WITH MASSIVE AND
GROWING AMOUNT OF WORK
• approaching 1 million articles
                                        1,000,000
  added to PubMed every year
• By the end of my talk several
                                         800,000
  new papers will be have been
  added....
                                         600,000


                           new pubmed    400,000
                             articles
                                         200,000


                                               0
                                                    1979 1984 1989 1994 1999 2004 2009

                                                                       year
HUMAN EFFORT AT MASSIVE SCALE




Seven million hours of human labor




                                     Empire State Building
HUMAN EFFORT AT MORE MASSIVE SCALE
     It is estimated that 9 billion
     hours of human labor were
     spent playing solitaire in
     2005.




Von Ahn L. : Google Tech Talk: Human Computation 2006.
HUMAN EFFORT AT TRULY MASSIVE SCALE
     Estimated that 150 billion hours spent playing games in 2010
                 1.6E+11

                 1.4E+11

                 1.2E+11

                  1E+11

                  8E+10

                  6E+10
                                                                      hours worked
                  4E+10

                  2E+10

                      0

                           empire state   one year of   one year of
                             building      solitaire      games

McGonigal J. Reality is broken : why games make us
better and how they can change the world.
New York: Penguin Press; 2011.
50
-
    150 billion human hours
              per year




                              http://www.flickr.com/photos/rvp-cw/6243289302/
Seven million hours of human labor =
     1




                                                         Empire State Building

Von Ahn L. : Google Tech Talk: Human Computation 2006.
150 billion hours of human game play =   nothing
150 billion hours of human game play =   nothing
GAMES WITH A PURPOSE


Label all images on the Web
                               Devise protein folding algorithms




                              Fix multiple sequence alignments
     Design RNA molecules
Annotate the human genome
genegames.org

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genegames.org

  • 1. CROWDSOURCING BIOCURATION WITH BIOLOGICAL GAMES Benjamin Good The Scripps Research Institute @bgood
  • 2. BIOCURATORS FACED WITH MASSIVE AND GROWING AMOUNT OF WORK • approaching 1 million articles 1,000,000 added to PubMed every year • By the end of my talk several 800,000 new papers will be have been added.... 600,000 new pubmed 400,000 articles 200,000 0 1979 1984 1989 1994 1999 2004 2009 year
  • 3. HUMAN EFFORT AT MASSIVE SCALE Seven million hours of human labor Empire State Building
  • 4. HUMAN EFFORT AT MORE MASSIVE SCALE It is estimated that 9 billion hours of human labor were spent playing solitaire in 2005. Von Ahn L. : Google Tech Talk: Human Computation 2006.
  • 5. HUMAN EFFORT AT TRULY MASSIVE SCALE Estimated that 150 billion hours spent playing games in 2010 1.6E+11 1.4E+11 1.2E+11 1E+11 8E+10 6E+10 hours worked 4E+10 2E+10 0 empire state one year of one year of building solitaire games McGonigal J. Reality is broken : why games make us better and how they can change the world. New York: Penguin Press; 2011.
  • 6. 50 - 150 billion human hours per year http://www.flickr.com/photos/rvp-cw/6243289302/
  • 7. Seven million hours of human labor = 1 Empire State Building Von Ahn L. : Google Tech Talk: Human Computation 2006.
  • 8. 150 billion hours of human game play = nothing
  • 9. 150 billion hours of human game play = nothing
  • 10. GAMES WITH A PURPOSE Label all images on the Web Devise protein folding algorithms Fix multiple sequence alignments Design RNA molecules