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Fluids, Electrolytes & IV Therapy
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Fluids, Electrolytes & IV Therapy


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  • To understand how iv therapy works to restore fluid and electrolyte balance, lets review some basics of fluids & electrolytes.
  • Intracellular – 55% of the total body fluid Extracellular:2 formsIntravascular (blood plasma) – liquid component of the blood. Surrounds RBCs & accounts for most of the blood volumeInterstitial ECF – transcellular fluid contains secretions from the salivary glands, pancreas, liver & sweat glandsGeneral composition of extracellular fluid:More Na+ , Cl- , HCO3 - Less K+, Ca++, Mg++, PO4-3, SO4-2General composition of intracellular fluid:More K+, PO4-3, Mg++, SO4-2 Less Na+ , Cl- , HCO3-
  • Maintaing fluid balance involves these organs.This balancing act affected by Fluid volumeDistribution of fluids in the bodyConcentration of solutes in the fluid
  • This balancing act affected by Fluid volumeDistribution of fluids in the bodyConcentration of solutes in the fluid
  • Daily fluid gains & lossesIntake – water of oxidation (combined water & oxygen in the respiratory system) – 300 – 400mlLungs (respiration)Skin (perspiration)Kidneys (urine)Intestines (feces)
  • ADH – referred as to water – conserving hormone – affects fluid volume & water concentration by regulating water retention.
  • Aldosterone acts to retain sodium and water. Its secreted when the serum sodium level is low, the potassium is high, or the circulating volume of fluid decreases.
  • Before carefully assessing a patient before and during IV therapy, you can identify fluid imbalances early – before serious complications develop.
  • Electrolytes are associated with electricity. These vital substances are chemical compounds that dissociate in solution into electrically charged particles called ions. Like wiring for the body, the electrical charges of ions conduct current that’s necessary for normal cell function
  • Fluids and electrolytes are usually discussed in tandem, especially where IV therapy is concerned, because fluid balance and electrolyte balance are interdependent. any change in one alters the other, and any solution given IV can affect a patient’s fluid and electrolyte balance.
  • Two ECF components – ISF & intravascular fluid – have identical electrolyte compositions. Pores in the capillary walls allow electrolytes to move freely between the ISF and plasma, allowing for equal distribution of electrolytes in both substances. The protein contents of ISF and plasma, however, ISF doesn’t contain proteins because protein molecules are too large to pass through capillary walls. Plasma has a high concentration of proteins.
  • Body fluids in constant motion although separated by membranes, they continually move between the major fluid compartments.
  • The sodium – potassium pump – it moves sodium ions out of cells to the ECF and potassium ions into cells from ECF. This pump balances sodium and potassium concentrations.
  • Lower serum – fluid overloadHigher serum – hemoconcentration and dehydration
  • Transcript

    • 2.
    • 3. Solutes
    • 5. Understanding body fluid distribution
    • 6.
    • 7.
    • 8. Daily Total Intake & Output 2,400 – 3,200ml
    • 9.
    • 10. Aldosterone
    • 11. Fluid imbalances
    • 12. Electrolytes
    • 14. Contain different electrolytes because the cell membranes separating the two compartments have selective permeability.
      Contain different solutes, concentration levels are about equal when balance is maintained.
    • 15.
      A mechanism that regulates fluid and electrolyte balance.
      Body fluids are in constant motion.
      Nutrients , waste products, and other substances get into and out of cells, organs, and systems.
      Influenced by membrane permeability and colloid osmotic and hydrostatic pressures.
    • 17. Solute & fluid molecules
    • 18. Solute & fluid molecules
    • 19.
    • 20.
    • 21. Osmosis
      Movement of water across a semipemeable membrane from an area of low solute concentration (less concentrated) to an area of high solute concentration (more concentrated).
    • 22. Capillary filtration and reabsorption
      Filtration – movement of substances from an area of high hydrostatic pressure to an area of lower hydrostatic pressure
      Hydrostatic pressure – pressure at any level on water at rest due to weight of the water above it.
      Pushes fluids and solutes through capillary wall pores and into the ISF.
      Capillary Reabsorptionby the osmotic or pulling force of albumin (Colloid Osmotic/Oncotic Pressure) - pulling force of albumin in the capillaries, attracting water in from the interstitial space
    • 23.
    • 24.
    • 26. Osmolarity
      Concentration of a solution.
      Expressed in milliosomols of solute per liter of solution (mOsm/L)
      Same osomolarity as other body fluids about 300 mOsm/L
    • 27. Three Main Types of IV Solutions
    • 28. Isotonic Solutions(240-340mOsm)
      Solution has the same solute concentration (or osmolality) as normal blood plasma (290mOsm) and other body fluids
      Solution stays where it is infused, inside the blood vessel
      Expands the intravascular compartment
      Does not affect the size of the cells
      Solution maintains body fluid balance
    • 29.
    • 30. Isotonic Solutions
    • 31. Isotonic Solutions
    • 32. Isotonic Solutions
      Nursing considerations
      Monitor patient for signs of fluid overload especially in patients with CHF and hypertension.
    • 33. Hypotonic Solutions
      Solution has a lower osmolarity than serum (less than 240 mOsm/L)
      Solution causes a fluid shift out of the blood vessels into the cells and interstitial spaces
      Solution hydrates cells while reducing fluid in the circulatory system
      Ex.: ½ NSS (0.45% NaCl)
    • 34. Hypotonic Solutions
    • 35.
    • 36. Hypotonic Solutions
      Nursing considerations
      Administer cautiously
      Solution can lower blood pressure
      Do not give if these solutions if the patient is at risk for:
      ICP from cerebrovascular accident
      Head trauma
    • 37. Hypertonic solutions
      Solution has an osmolarity higher than serum(>340mOsm/L)
      Causes the solute concentration of the serum to increase pulling fluid from the cells and the interstitial compartment into the blood vessels
      Reduces the risk of edema, stabilizes blood pressure, and regulates urine output
    • 38. Hypertonic Solutions
    • 39.
    • 40. Hypertonic Solutions
    • 41. Hypertonic Solutions
      Nursing considerations
      Monitor your patient for circulatory overload
      Solution can be irritating to the vein
    • 42. Two Main Groups of IV Solutions
    • 43. Crystalloids
      Are isotonic and remain isotonic in the vasculature and are therefore effective volume expanders for a short period of time.
      Ideal for patients who need fluid volume replacement
      Ex.: Lactated Ringer’s (LR), Normal Saline (NS)
    • 44. Colloids
      Used to increase vascular volume rapidly drawing fluid from the interstitial and intracellular compartments into the vascular compartment.
      They work well in reducing edema (as in pulmonary or cerebral edema) while expanding the vascular compartment. 
      Examples: albumin, mannitol, dextran, hetastarch, gelafundin, Haesteril
    • 45. Colloids
      Polysaccharide fluid
      Natural plasma protein from donor plasma
      Sugar alcohol substance
      Synthetic colloid made from starch
    • 46. Thank you and have a good day!