HIPERBILIRRUBINEMIA CAUSAS TRATAMIENTO

HIPERBILIRRUBINEMIA HOSPITAL VICTOR RAMOS GUARDIA DEPARTAMENTO DE PEDIATRIA IM: JORGE SOLAR ROSSEL

DEFINICIONES ,[object Object],[object Object]

EPIDEMIOLOGÍA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

FACTORES DE RIESGO ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

METABOLISMO DE LA BILIRRUBINA ,[object Object],[object Object],[object Object],[object Object],Eritropoyesis Ineficaz Hemoproteínas Hem Libre Hemoglobina 75% 25% HEME Hemeoxigenasa Biliverdina CO2 Biliverdina Reductasa Bilirrubina NO Conjugada + Albúmina Carboxihemoglobina Oxigeno Oxihemoglobina CO Exhalado

MANIFESTACION CLINICA ,[object Object], Zona 1 : 4 a 7 mg/dl; Zona 2 : 5 a 8,5 mg/dl; Zona 3 : 6 a 11,5 mg/dl; Zona 4 : 9 a 17 mg/dl; Zona 5 : > de 15 mg/dl. Hay gran variabilidad en la apreciación subjetiva de la ictericia. Adaptado de Kramer: AJDC 1069;118:454 y Finn: Acta Obstet Gynecol Scand 1975; 54:329.

EFECTOS TÓXICOS DE LA BILIRRUBINA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

KERNICTERUS ,[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

HIPERBILIRRUBINEMIA FISIOLOGICA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

HIPERBILIRRUBINEMIA FISIOLOGICA ,[object Object],[object Object],[object Object],[object Object]

HIPERBILIRRUBINEMIA NO FISIOLOGICA ,[object Object],[object Object],[object Object],[object Object]

HIPERBILIRRUBINEMIA NO FISIOLOGICA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

HIPERBILIRRUBINEMIA NO FISIOLOGICA ,[object Object],[object Object],[object Object],[object Object],[object Object]

HIPERBILIRRUBINEMIA POR LACTANCIA MATERNA ,[object Object],[object Object],[object Object],[object Object]

ENFERMEDAD HEMOLÍTICA DEL RN ,[object Object],[object Object]

E H. : CARACTERÍSTICAS CLÍNICAS HEPATOMEGALIA ESPLENOMEGALIA ICTERICIA PRECOZ RH + + ++ ABO - - + ANEMIA HIDROPS T.DE COOMBS ++ + + - - +/-

ESTUDIO HIPERBILIRRUBINEMIA NEONATAL: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

TRATAMIENTO: ,[object Object],[object Object],[object Object]

FOTOTERAPIA ,[object Object],[object Object],[object Object],[object Object]

EXANGUINEOTRANSFUSIÓN ,[object Object],[object Object],[object Object],[object Object]

FARMACOS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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