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Bladder Cancer R. Zenhäusern
Bladder cancer: Epidemiology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Bladder cancer: Histology ,[object Object],[object Object],[object Object],[object Object]
Bladder cancer: Entities ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Bladder cancer:  Stage and Prognosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Superficial Bladder Cancer pTa, pT1, Tis ,[object Object],[object Object],[object Object],[object Object]
Superficial Bladder Cancer ,[object Object],[object Object],[object Object],[object Object]
Superficial Bladder Cancer Adjuvant Therapy ,[object Object],[object Object],[object Object],[object Object]
Invasive bladder cancer ,[object Object],[object Object],[object Object]
Results of radical cystectomy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Results of radical cystectomy ,[object Object],[object Object],[object Object],[object Object],[object Object]
Chemotherapy for bladder cancer ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Chemotherapy for bladder cancer ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Adjuvant chemotherapy ,[object Object],[object Object],[object Object],[object Object],[object Object]
Neoadjuvant chemotherapy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Combined Radio- and Chemotherapy ,[object Object],[object Object],[object Object],[object Object],Birkenhake et al. Strahlenther Onkol 1998;174:121
Bladder-sparing therapy for invasive bladder cancer ,[object Object],[object Object],[object Object],[object Object]
Bladder-sparing protocol Transurthral resection Induction Therapy: Radiation + chemotherapy   (cisplatin, paclitacel) Cystoscopy after 1 month no tumor tumor Consolidation: RT + CT cystectomy
Bladder-sparing protocol Shiply et al. Urology 2002;60:62 T2: 5y / 10y OS: 74% / 66% T3-T4a: 5y / 10y OS: 53% / 52%
Results of bladder-sparing therapy and cystectomy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Combined-modality treatment and organ preservation in invasive bladder cancer ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Combined-modality treatment and organ preservation in invasive bladder cancer ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Local control Distant metastasis Rödel et al. JCO 2002;20:3061
Disease-specific survival for patients after salvage cystectomy 50% 45% 21% 18% Rödel et al. JCO 2002;20:3061
TUR and adjuvant  Radio-Chemotherapy ,[object Object],[object Object]

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