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ROBB FRALEY
CHIEF TECHNOLOGY OFFICER




MONSANTO EUROPEAN INVESTOR DAY



November 10, 2006



                                 1
OVERVIEW

  R&D Focus Aligns With Growth Drivers to Extend Leadership
  Through 2010

                                                                                                                                SITUATION              R&D
                                                                                                             FACTOR             ANALYSIS           APPLICATION
               MONSANTO’S R&D OPPORTUNITY
                                                                                                                                                    BREEDING
                                                                                                                              Growing demand
                                                                                                             U.S. corn        pressures feed
            Application of our breeding and biotech
                                                                                                                                                     BIOTECH
            capabilities fully supports our six gross                                                                         and fuel supply
            profit drivers
                                                                                                                              Better yields
                                                                                                             International    needed to
                                                                                                                                                    BREEDING
                                                                                                             corn             improve global
               DISCOVERY          PHASE I             PHASE II
  R&D PHASE:                                                          PHASE III     PHASE IV       LAUNCH
                                                                                                                              competitiveness

                                            BREEDING                                                                          Opportunity exists
                                                                                                             Global biotech   to upgrade plant
                                                                                                                                                     BIOTECH
                                                                                      COMMERCIAL
                                                        IT PLATFORM
                                          GERMPLASM




G
                                                                        ANALYTICS
                                MARKERS




                                                                                                             traits           performance with
                     GENOMICS




                                                                                                   SEED
                                             ELITE




Germplasm                                                                                                                     traits
                                                                                                   SOLD TO
                                                                                                   FARMERS
        R                                                                                                                     Improve global
                                                                                                                                                    BREEDING
                                                                                                                              productivity
                                  BIOTECHNOLOGY                                                              Cotton
                                                                                                                              through
                                                                                                             platform
                                                                                                                              technology
                                                                                                                                                     BIOTECH
                                                                                                                              infusion

                                                                                                                              Highly fragmented
                                                                                                                                                    BREEDING
                                                                                                             Seminis          market, ready for
                                                                                                                              new technology
                                                                                                                              Deliver higher
                                                                                                                              value
                                                                                                                                                     BIOTECH
                                                                                                             R&D pipeline
                                                                                                                              technologies
                                                                                                                              faster

                                                                                                                                                                 2
OVERVIEW

        Farmers Buy Yield; Our R&D Approach Oriented
        Around Meeting That Customer Need
                R&D APPROACH
                                                                                                  PERCENT OF GENETIC
                     YIELD                             GENETIC POTENTIAL
FARM APPROACH




                                                                                                    GAIN PRESERVED
                                            =                                               X
                Farmer’s Purchase                Inherent yield possible from the seed            Amount of yield potential
                    Decision
                                                                          BREEDING
                                                GERMPLASM                                               protected

                           =
                       SEED
                • Starting point of all
                  agriculture; farmers
                  maximize genetics in
                  seed for yield
                • 60% of farmers select • Germplasm library
                                                                    • >2,000 genetic
                  seed first, then                                                              • Monsanto is only
                                          assembled from              markers used by
                  decide on biotech
                                                                                                  company to develop
                                          36 programs in 12
                  traits                                              breeders for corn
                                                                                                  and commercialize
                                              countries
                          X
                                                                      today
                                                                                                  complete above-
                                            • >100 breeding         • 50% of breeding             ground, below-ground
                                              research centers        population comes            insect-control and
                                              worldwide               from inter-company,
                TECHNOLOGY                                                                        weed-control traits
                                                                      inter-country
                                                                      crosses
                • Technology is used to
                  protect and maximize                              • Molecular breeding
                  yield potential of seed                             improves genetic
                                                                      potential by 2X
                                                                      versus conventional
                                                                      breeding


                                                                                                                              3
BREEDING

   Monsanto’s Global Breeding Engines Deliver Yield
   Advantages Over Best-in-Class Competitors

                                                                         2006 PRELIMINARY U.S.
                                                                   COMPETITIVE CORN YIELD COMPARISON
                                                200

                                                          DEKALB
           U.S. Corn
                                                195
SITUATION:
                                                          COMPETITORS
• Top 3 purchase drivers for
                                 BUSHELS/ACRE
  farmers buying DEKALB                         190
  corn seed all relate to
  performance of underlying
                                                185
  germplasm
OUTLOOK:

• Preliminary yield data                        180
  from 2006 indicates
  continued yield advantage
                                                175
  versus best-in-class
  competitors
• Final data will be shared in                  170
                                                                          RELATIVE MATURITIES (DAYS)
  January
                                                                                                           115
                                                          95            100       105
                                                                                               110
                                                        YIELD ADVANTAGE

                                                      In 2006, across the 110-day maturity zone that covers one-third
                                                      of U.S. corn production, DEKALB outperformed the competition
                                                      by roughly 11 bushels per acre on average
                                                                                                                        4
BREEDING


  Best Combination of Germplasm and Traits Delivers
  Best Yield
                                            FOCUS: YIELD PER ACRE (PRELIMINARY)
             U.S. Corn
                                                                         194                              YieldGard
                                                        200
SITUATION:
                                                                         bu/ac                            Rootworm or




                                    BUSHELS PER ACRE
                                                                                                182.4
• In 2006, across four states and                                                                         YieldGard Plus
                                                        190
                                                                                                bu/ac
  267 locations, DEKALB seed
                                                                                                          Herculex®
  with YieldGard Rootworm or                            180                                               Rootworm or
  YieldGard Plus outperformed                                                                             Herculex XTRA
                                                        170
  competitive seed and trait
  performance by roughly 10
                                                        160
  bu/ac on average
• In 2006, across 81 locations,                         150
                                                                       DEKALB                  PIONEER
  statistically there is no
  difference between the
  performance of YieldGard
  Rootworm or YieldGard Plus            FOCUS: TRAIT PERFORMANCE - ROOT PROTECTION (PRELIMINARY)
  and competitive traits
                                                        0.25                                             YieldGard Rootworm
                                                               Difference between two traits
OUTLOOK:
                                    NODE INJURY SCALE




                                                                                                         or YieldGard Plus
                                                               statistically insignificant
                                                        0.20
• Farmers make their seed                                                                                Herculex®
                                                                                                 .20
  purchase decision on the total                                                                         Rootworm or
                                                                           .17
                                                        0.15                                             Herculex XTRA
  system performance of the
  seed-and-trait package versus
                                                        0.10
  the trait or germplasm
  individually
                                                        0.05

                                                        0.00
                                                                                               PIONEER
                                                                      DEKALB

                                                                                                                              5
BREEDING

   Breeding Advances in France Fuel Market Share Growth


                                               CORN GRAIN HYBRID
    International Corn
                                             REGISTRATION – FRANCE
SITUATION:

                                                   2003 - 2005
• From 2003 – 2005,
  Monsanto led the way with
  36 new corn grain hybrids
                                  60
  or 19% of the total new                                                                     51
  product entrants approved       50
  in France
                                  40
• DEKALB market share has                                                                               35
                                                                                                   29
  grown 5 points over last
                                  30
  two years
• For first time ever,            20                    15
                                             12   13
                                        11
  DEKALB is co-leading
                                                                               6
                                  10
  brand in France                                                   6
                                                             4
                                                                                     2    2
OUTLOOK:
                                   0
                                         MONSANTO         PIONEER              SYNGENTA        ALL OTHER
• Yield data will be shared in
  January
                                                             2003       2004       2005
• Corn grain hybrid
  registration in France will
                                   BREEDING ACCELERATION
  be updated
                                 From 2003 – 2005, Monsanto registered more hybrids than its primary
                                 competitors across broadest growing regions, accounting for 19% of
                                 all newly registered hybrids in France

                                                                                                             6
BREEDING


  Corn Market Share Gains Still To Fully Reflect Power of
  Molecular Breeding Application

                                                                                                           MOLECULAR-BREEDING HYBRIDS
                                                                                                           AS A PERCENT OF BRANDED
       U.S. and                                                                                            UNITS SOLD IN COMMERCIAL
                                                  20%
  International Corn                                                        2006 BRANDED U.S.              CORN PORTFOLIO

                                                                                                                                        12%
                                                                            MARKET SHARE: 19%




                                                                                                                                              IN COMMERCIAL CORN PORTFOLIO
                                                                                                                                              PERCENT OF BRANDED UNITS SOLD
SITUATION:



                                                                                                                                        10%
• Conventional breeding
                                                  15%
                              U.S. MARKET SHARE
  improves genetic gain
  on average by 1.5% per
                                                                                                                                        8%
  year
                                                  10%             DEKALB AND ASGROW
OUTLOOK:
                                                                                                                                        6%
                                                                  U.S. BRAND MARKET
                                                                  SHARE
• Molecular breeding
  improves genetic
                                                                                                                                        4%
                                                  5%
  potential by 2X versus
  conventional breeding
                                                                                                                                        2%
• By 2010, over 12% of
  commercial portfolio will
                                                  0%                                                                                    0%
  be derived from
  molecular breeding                                      2001   2002      2003   2004    2005    2006   2007F 2008F 2009F 2010F
                                                        CYCLE 1:                  CYCLE 2:                  CYCLE 3:
                                                        INTEGRATION OF            APPLICATION OF MAB        SELECTION POWER OF
                                                        GLOBAL GERMPLASM          TO SELECTION              MOLECULAR BREEDING

                                                                                                         • BY 2006, FIRST MOLECULAR
                                                        • ASSEMBLED 36 MAJOR      • PREDICTIVE
                                                                                                           BREEDING HYBRIDS ENTER
                                                          CORN BREEDING             COMBINATIONS ALLOW
                                                                                                           U.S. COMMERCIAL
                                                          PROGRAMS IN 12            MORE EFFICIENT
                      PROGRESSION
                                                                                                           PORTFOLIO
                                                          COUNTRIES                 BREEDING
                       OF BREEDING
                      TECHNOLOGY                                                                         • EU IS ROUGHLY 2 YEARS
                                                        • FIRST INTRA-COMPANY     • APPLY MOLECULAR
                             IN THE                                                                        BEHIND THE U.S. FOLLOWED
                                                          CROSSES                   BREEDING TO TROPICAL
                       COMMERCIAL                                                                          BY LATIN AMERICA AND ASIA
                                                                                    MARKETS, SUCH AS
                         PORTFOLIO                                                                         PACIFIC
                                                                                    BRAZIL AND ASIA

                                                                                                                                                                              7
BREEDING

  Seminis R&D to Focus on Top Five Crops Supported by
  Molecular Marker Platforms

                            TOP 5 CROPS
           Seminis
                                                   STRATEGIC FOCUS                 INVESTMENTS
SITUATION:

                                            • Consumer benefits such as
• In 2006, narrowed                           flavor and seedless                • Advance
                                  Tomato
  commercial focus to 25
                                                                                   molecular markers
                                            • Grower benefits such as disease
  crops that generate
                                              resistance
  most profit

                                            • Consumer benefit traits such as    • Advance
OUTLOOK:
                             Sweet pepper
                                                                                   molecular markers
                                              shape, sweetness and color
• Significant marker
  platforms to support                      • Novel flavor for consumers
  advancements in quality                                                        • Increase breeding
                                            • Grower yield through hybrid
  and consumer traits for                                                          investments in
                               Hot pepper
                                              conversion and disease
  top 5 crops                                                                      NAFTA
                                              resistance
                                                                                 • Advance
                                            • Consumer benefits such as            molecular markers
                                              firmness, sugars, shelf life and
                                   Melon
                                                                                 • Strengthen
                                              flavor
                                                                                   germplasm
                                                                                 • Strengthen
                                            • Aggressive hybrid conversion for
                                                                                   germplasm
                                              yield and uniformity
                                   Onion
                                                                                 • Advance
                                            • Reduce pungency for consumers        molecular markers


                                                                                                       8
BREEDING

    Genetic Mapping Timetable Supports Commercial
    Launches of Molecular Breeding Hybrids by End of Decade


                                                                              MARKER PLATFORMS
                                                                    MARKER APPLICATION FOR KEY CROPS (2006-2009)
        Seminis
SITUATION:
                                                         5,000   SWEET CORN
• Began application of
                           NUMBER OF MARKERS DEVELOPED


  breeding technology,
  with genome-wide
  marker platform for
  tomatoes and peppers
• Melons, watermelons                                                                                               TARGET:
                                                         1,000
  and brassica family of                                                                                            1,000 markers
  cabbage, broccoli and
  cauliflower next
OUTLOOK:
                                                                 BRASSICA
• By 2009, Seminis                                        500    TOMATO
  should have 1,000+
                                                                 MELON
  markers for 9 crops                                            WATERMELON


                                                                 PEPPER

                                                                 ONION,
                                                                 CUCUMBER,
                                                                 LETTUCE

                                                                                                            2009F
                                                                                 2007F         2008F
                                                                  Current
                                                                  Status

                                                                                                                                    9
BIOTECHNOLOGY

Top-Ten Traits Poised to Deliver Significant Value
                                                             PIPELINE VALUE: TOP-TEN PROJECTS
                                                                        REFLECTING COMMERCIAL VALUE1
                                                                                            VALUE PER    ACRE     CORE
                                                          PHASE        SOURCE OF VALUE
                                                                                              ACRE       BASE    MARKETS

         Renessen Corn Processing System                                                                            U.S
                                                            4                                                      Brazil
                                                                                            $10 - $30    20M
         and Mavera™ High-Value Corn with                                Feed and fuel
                                                                                                                  Europe
                                  Lysine2
                                                                                                                    U.S.
  HIT




                                                            3
           Roundup RReady2Yield soybeans                                                    $10 - $30   155M       Brazil
                                                                      Yield enhancement
                                                                                                                 Argentina

                                                            3
                                Omega-3 soybeans                                              >$30       5M        U.S.
                                                                        Improved health
                                                                                                                    U.S.
                                                            3
                                 YieldGard VT PRO                                           $10 - $30    41M       Brazil
                                                                        Insect protection
                    2 -GEN YIELDGARD CORN BORER
                      nd
                                                                                                                  Europe
                                                                                                                    U.S
                                                            2
  HIT




                                                                       Water replacement
                             Drought-tolerant corn                                          $10 - $30   164M       Brazil
                                                                           and yield                              Europe
  HIT




                                                            2                                                      U.S.
                               Vistive III soybeans                                         $10 - $30   12-15M
                                                                        Improved health

                                                                                                                    U.S.
                                                            2
                     Higher yielding soybeans                                               $10 - $30   155M       Brazil
                                                                      Yield enhancement
                                                                                                                 Argentina

                                                            2                                                      Brazil
                                                                        Yield and insect
                    Insect-protected soybeans                                               $20 - $40    95M
                      WITH ROUNDUP RREADY2YIELD                                                                  Argentina
                                                                           protection
                                                                                                                    U.S.
                                                            1                                                      India
                                                                       Water replacement
                           Drought-tolerant cotton                                          $10 - $30    36M       Brazil
                                                                           and yield
                                                                                                                 Australia
                                                                                                                    U.S
                                                            1        Nitrogen replacement
                           Nitrogen utilization corn                                        $10 - $30   164M       Brazil
                                                                           and yield                              Europe
        1. Top ten not presented in ranked   2. Value and acres are for direct
            order; Commercial value             feed piece only and do not
            calculated by penetration and       include value for Renessen’s corn
            retail value during three-year      processing system, which is to be
            span at peak.                       determined
                                                                                                                             10
BIOTECHNOLOGY


  Roundup RReady2Yield Soybeans Offer Yield Improvement
  Over First-Generation Roundup Ready Soybeans
                                                                    KEY MARKET ACRES       U.S.   BRAZIL   ARGENTINA

                            Roundup RReady2Yield                    AVAILABLE MARKET       70M     50M        35M

                            Soybeans                                PERCENT PENETRATED      0%     0%         0%
    P   R   O   JE   CT



                                                       ROUNDUP RREADY2YIELD IN THE FIELD
                                                                   FIELD TRIAL PHOTOS FROM 2006
                R&D Pipeline
  HIT            Roundup
Project          Ready2Yield soybeans      LOCATION:
                                            Stonington, Illinois
SITUATION:
                                           ACTIVITY:
                          On Track
     2006 STATUS:                           Monsanto
                                            researchers check
• Yield data from 45 trials will be         performance
  shared in January                         indicators in the
                                            fields such as plant
VALUE CONSIDERATIONS:                       height, and pod size
                                            and number
• Value is additive, with target of
  up to 5 bushel-per-acre yield            OBSERVATIONS:
  improvement over comparable               25 locations across
                                            the U.S. tested
  Roundup Ready soybeans
                                            11,000 lines tested
            RETAIL
                          $10 - $30/acre
        VALUE/ACRE:                         in 45 trials
      TOTAL ACRE
                          155M acres
    OPPORTUNITY:




                                                                                                                    11
BIOTECHNOLOGY

  Reflecting HIT Status, Roundup RReady2Yield Soybeans Is
  Targeted for Monsanto’s Most Significant Commercial Launch
                                                                                     KEY MARKET ACRES            U.S.     BRAZIL    ARGENTINA

                               Roundup RReady2Yield                                  AVAILABLE MARKET            70M        50M         35M

                               Soybeans                                              PERCENT PENETRATED          0%         0%          0%
     P    R   O   JE   CT


                                                                                           LAUNCH ACRES OF U.S. TRAITS
                                                                    3
                                                                                     HISTORICAL COMMERCIALIZED TRAITS (1996-2006)
                  R&D Pipeline
                                                                   2.5




                                             ACRES (IN MILLIONS)
                   Roundup
  HIT                                                                                AVERAGE HISTORIC
                                                                    2
                   RReady2Yield                                                      TRAIT LAUNCH:
Project                                                                              1.2M ACRES
                   soybeans                                        1.5
SITUATION:
                                                                    1
                            On Track
     2006 STATUS:
                                                                   0.5
• Yield data from 45 trials will be
                                                                    0
  shared in January                                                                             SOYBEAN TRAITS
                                                                                                                        COTTON TRAITS
                                                                            CORN TRAITS
VALUE CONSIDERATIONS:

                                                                   Target acreage for Roundup RReady2Yield commercial
• Value is additive, with target of
  up to 5 bushel-per-acre yield                                    launch is expected to be a multiple above historical acreages
  improvement over comparable                                      in launch years
  Roundup Ready soybeans
             RETAIL                                          ROUNDUP RREADY2YIELD: COMMERCIAL MILESTONES
                            $10 - $30/acre
         VALUE/ACRE:
                                                                         STARTING POINT
                                                                         U.S. REGULATORY
      TOTAL ACRE                                                         APPROVAL
                            155M acres
    OPPORTUNITY:
                                                                                SEASON 1                         LAUNCH YEAR
                                                                         GLOBAL REGULATORY CLEARANCES



                                                                         PRE-COMMERCIAL USER-RELIABILITY           COMMERCIAL LAUNCH
                                                                                    TRIALS



                                                                                                                                              12
BIOTECHNOLOGY

  Tests of Drought-Tolerant Corn Continue to Validate
  Concept
                                                                       KEY MARKET ACRES     U.S.   BRAZIL   EUROPE

                              Drought-tolerant                         AVAILABLE MARKET     80M     30M      24M

                              corn                                     PERCENT PENETRATED   0%      0%        0%
     P   R   O   JE   CT



                                                  DROUGHT TOLERANT CORN IN THE FIELD
                  R&D Pipeline                                     FIELD TRIAL PHOTOS FROM 2006
HIT Project            Drought-tolerant corn

SITUATION:

                             On Track
         2006 STATUS:
                                               LOCATION:
• Continued expansion of testing in lead         Vacaville, California
                                               ACTIVITY:
  genes and events in moisture-stressed
                                                 Monsanto
  and broad acre environments
                                                 researcher checks
• Currently testing hundreds of genes            performance
  across several generations of drought          indicators in the
  traits                                         field such as
                                                 chlorophyl content,
• Results will be shared in January              ear size, and plant
                                                 height
VALUE CONSIDERATIONS:

                                               OBSERVATIONS:
• Value of trait reflects better yields
                                                 Confirming third
  under moisture-stressed conditions
                                                 year of field trial
• Value will be specific to variable costs       data in U.S.
  of water use by farmers, rather than
  fixed costs of irrigation
         RETAIL
                           $10 - $30/acre
     VALUE/ACRE:

      TOTAL ACRE
                           164M acres
    OPPORTUNITY:

                                                                                                                     13
BIOTECHNOLOGY

  Multi-Generational Drought-Tolerant Corn to Create
  Value Across Multiple Market Segments
                                                                KEY MARKET ACRES                  U.S.        BRAZIL        EUROPE

                            Drought-tolerant                    AVAILABLE MARKET                   80M          30M            24M

                            corn                                PERCENT PENETRATED                 0%            0%             0%
     P   R   O   JE   CT



                                                         SEGMENTED VALUE OPPORTUNITY
                                                        ACROSS MARKETS: EUROPE EXAMPLE
                      R&D Pipeline
  HIT Project                                                                                                       Drought Monitor
                            Drought-tolerant corn
                                                                                                               D0: Abnormally Dry
SITUATION:                                                                                                     D1: Drought - Moderate

                                 On Track
                  2006 STATUS:                                                                                 D1: Drought - Severe
                                                                                                               D1: Drought - Extreme
• Continued expansion of testing in lead genes
                                                                                                               D1: Drought - Exceptional
  in moisture-stressed and broad acre
  environments.
• Currently testing hundreds of genes across
  several generations of drought traits
                                                    Source: UCL Department of Space and Climate Physics
• Results will be shared in January
VALUE CONSIDERATIONS:
                                                        IRRIGATED                DRYLAND                  STABILITY
• Value of trait reflects better yields under       Irrigated               Non-Irrigated           Non-Irrigated
  moisture-stressed conditions; varies by
                                                    Value is in             Value is in             Value is in
  region (see table at right)
                                                    replacing               improved yields         improved yields
• Value will be specific to variable costs of       irrigation, reducing    annually, by            when moisture is
  water use by farmers, rather than fixed costs     variable costs of       improving water-        less than optimal
                                                    irrigation              use efficiency
  of irrigation
    RETAIL VALUE/ACRE:       $10 - $30/acre
               TOTAL ACRE
                             164M acres
             OPPORTUNITY:

                                                                                                                                           14
BIOTECHNOLOGY

  Vistive III Soybeans Have Potential To Leapfrog on
  Commercial Development Track
                                                                    KEY MARKET ACRES                  U.S.

                            Vistive III Soybeans                    AVAILABLE MARKET              12-15M

                                                                    PERCENT PENETRATED                0%
     P   R   O   JE   CT


                                                           VISTIVE III
                                                   FIELD TRIAL PHOTOS FROM 2006
                 R&D Pipeline
   HIT                Vistive III Soybeans
 Project
SITUATION:
                                                                                  LOCATION:
                           On Track
         2006 STATUS:
                                                                                       Sperry, Iowa
                                                                                  ACTIVITY:
• Field trial results on oil composition
                                                                                       2006 summer
  and oil yield will be reviewed in
                                                                                       agronomic
  January
                                                                                       testing
VALUE CONSIDERATIONS:
                                                                                  OBSERVATIONS:
• Approximately 40M acres of U.S.                                                      First broad acre
  soybean crop is crushed for oil;                                                     field testing in
                                                                                       U.S. with lead
  Vistive III is optimal for non-
                                                                                       events
  hydrogenated and hydrogenated-
  frying segments
• Vistive III has potential to be priced
  at a premium to conventional
  soybean oil
RETAIL VALUE/ACRE:         $10 - $30/acre
       TOTAL ACRE
                           12M - 15M acres
     OPPORTUNITY:



                                                                                                             15
BIOTECHNOLOGY

Vistive III Soybeans Meet Multiple Needs in Food
Industry                                   KEY MARKET ACRES                                                               U.S.

                                                                                            AVAILABLE MARKET             12-15M
                         Vistive III Soybeans
  P   R    O   JE   CT                                                                      PERCENT PENETRATED                0%


                                                                                                                CONSUMER
                                              VISTIVE                                                           MARKET
               R&D Pipeline                   FAMILY
                                                                                                                OIL FOR
  HIT               Vistive III Soybeans                                                                        FRYING AND
                                                                   IMPROVED SOYBEAN
Project                                                                                                         SPRAYING
                                                                   QUALITY FOR LIQUID OILS
SITUATION:                                                                                                      Crackers
                                                                                                                Snack chips
                         On Track
      2006 STATUS:

• Field trial results on oil
  composition and oil yield will be                                 IMPROVING NUTRITIONAL
  reviewed in January                                               PROFILE OF SOYBEAN OIL
VALUE CONSIDERATIONS:                                          LINOLENIC       LINOLEIC         OLEIC     SATS
                                                                  18:3           18:2            18:1   18:0 / 16:0
• Approximately 40M acres of U.S.                    STANDARD
                                                      SOYBEAN
  soybean crop is crushed for oil;
  Vistive III is optimal for non-
                                             TARGET: VISTIVE III
  hydrogenated and hydrogenated-           LOW-LIN – MID-OLEIC –
                                            LOW-SAT SOYBEANS
  frying segments
• Vistive III has potential to be                        Major market segments for U.S. soybean oil
  priced at a premium to                                  NON-             HYDROGENATED-       HYDROGENATED-
                                                      HYDROGENATED            FRYING              BAKING
  conventional soybean oil
              RETAIL                                 For salad oils,       For various         For various
                         $10 - $30/acre
          VALUE/ACRE:
                                                     household use         frying              baking
        TOTAL ACRE                                                         applications        applications
                         12M – 15M acres
      OPPORTUNITY:
                                                     Uses 50% of           Uses 25% of         Uses 25% of
                                                     total crushing        total crushing      total crushing
                                                     (~20M acres)          (~10M acres)        (~10M acres)
                                                                                                                                   16
BIOTECHNOLOGY

   Omega-3 Soybeans Have Met Early Development
   Targets for Both Food Application and Field Performance
                                                                                              KEY MARKET ACRES      U.S.
                        Omega-3 soybeans                                                      AVAILABLE MARKET      5M
                                                                                              PERCENT PENETRATED    0%
        R&D Pipeline
      Omega-3 soybeans
                                    OMEGA-3 OIL TASTE RESULTS FROM 2005
SITUATION:


               On Track
     STATUS:
                                                     10


                                      TASTE RATING
• Extensive field testing for
                                                     5
  lead events in U.S.
                                                     0
• Food formulation results will
                                                                       Omega-3
  be shared in January
                                                          Soy Oil      SDA Oil         Fish Oil
VALUE CONSIDERATIONS:

• Value created through a                                    Taste Rating 0-15 Scale
  product with similar profile                            Score of zero indicates no flavor
  to soybean oil in taste, shelf-
  life and oil stability but with   In taste-testing, Omega-3 oil containing
  a superior nutritional and        stearidonic acid (SDA) oil compares
  taste profile to fish oil         favorably versus fish oil and commodity
     RETAIL                                                                                             Salad Dressing
                                    soy oil
               >$30/acre
 VALUE/ACRE:
                                                                                                        with SDA Oil
                                    Testing also focused on field performance,
  TOTAL ACRE
                                    demonstrating Omega-3 soybean yield on
               5M acres
OPPORTUNITY:
                                    par with commodity soybeans – an
                                    important factor to farmers growing
                                    specialty crops


                                                                                                                           17
BIOTECHNOLOGY

   Early Field Testing Indicates Nitrogen Utilization Corn Offers
   Yield Benefits in Both Limited and Normal Nitrogen Conditions
                                                               KEY MARKET ACRES        U.S.   BRAZIL   EUROPE
                            Nitrogen utilization
                            corn
                                                               AVAILABLE MARKET        80M     30M      24M
                                                               PERCENT PENETRATED      0%       0%       0%

                                                            NITROGEN CONTROL TESTING
        R&D Pipeline
   Nitrogen utilization corn
SITUATION:
                                   LOCATION:
                    On Track
        STATUS:                     Morrisonville,
                                    Illinois and
• Continued expansion of            Jerseyville, Illinois
                                   ACTIVITY:
  testing in limited and normal
                                    Field control
  nitrogen environments
                                    testing to measure
• Results will be shared in         nitrogen uptake
  January                           and to screen
                                    genes for nitrogen
VALUE CONSIDERATIONS:
                                    utilization
• Value created through            OBSERVATIONS:
  improved yield in both            Under normal
  limited and normal nitrogen       nitrogen, corn has
  environments                      good chlorophyll
                                    content, normal
     RETAIL
                  $10 - $30/acre
 VALUE/ACRE:                        ear development
                                    and higher yield
  TOTAL ACRE
                  164M acres
OPPORTUNITY:




                                       Limited Nitrogen                           Normal Nitrogen

                                                                                                                18
BIOTECHNOLOGY

   Nitrogen Utilization Technology Extends Benefits Across
   Crop Families
                                                                                    KEY MARKET ACRES      U.S.       CANADA          EUROPE
                            Nitrogen utilization
                            canola
                                                                                    AVAILABLE MARKET      1-2M         12-14M         12-14M
                                                                                    PERCENT PENETRATED     0%            0%                0%


                                                                      2006 NITROGEN
        R&D Pipeline
                                                                  CANOLA CONTROL TESTING
  Nitrogen utilization canola
SITUATION:
                                                      1800
                    On Track
        STATUS:

                                                      1700
• Continued expansion of
  testing in limited and normal
                                   YIELD (LBS/ACRE)




                                                      1600
  nitrogen environments
                                                                                                                 NITROGEN UTILIZATION
                                                                                          15%            9%
• Results will be shared in                                                                                      CANOLA
                                                      1500                                                       OBSERVATIONS:
                                                                                                 16%
  January
                                                                                                                 Significant increase in pod
                                                                                 11%                             development
                                                      1400
VALUE CONSIDERATIONS

• Value created through
                                                      1300
  improved yield in both                                     18%
  limited and in normal
                                                      1200
  nitrogen environments
     RETAIL
                  $10 - $30/acre                      1100
 VALUE/ACRE:

                                                             0             50            100     150      200
  TOTAL ACRE
                  25-30M acres
OPPORTUNITY:
                                                                     NITROGEN APPLIED (LBS/ACRE)
                                                                                                                  CANOLA CONTROL
                                                                 Conventional use rate
                                                                                                                  OBSERVATIONS:
                                                                 Nitrogen gene
                                                                                                                  Significantly less pod
                                                                                                                  activity
                                                                 Control
                                                                                                                                                19
BIOTECHNOLOGY

    Opportunity in Renewable Fuels Is Driving Yield Demand in
    Agriculture
                                                      U.S. & BRAZIL ETHANOL OUTLOOK
                                                                                                                                                  ETHANOL
                                 30                                                                                    45

                                                                                                                                                  ASSUMPTION
          BILLIONS OF GALLONS




                                                                                                                       40




                                                                                                                              MILLIONS OF ACRES
                                 25
                                                                                                                                                  • MTBE replacement by
                                                                                                                       35

                                                                                                                                                    2010 is base case
                                 20                                                                                    30

                                                                                                                                                  • Incremental yield
                                                                                                                       25
                                                                                                                                                    gains through
                                 15
                                                                                                                       20
                                                                                                                                                    technological
                                 10                                                                                    15
                                                                                                                                                    innovations allow
                                                                                                                                                    further substitution
                                                                                                                       10
                                  5
                                                                                                                       5

                                  0                                                                                    0
                                       2005   2006   2007   2008   2009    2010    2011   2012   2013   2014    2015

                                                                                    CORN
                                                                    U.S.
                                                                                    SUGAR CANE
                                                                    BRAZIL

                                                                                                                                                  BIODIESEL
                                  4                                                                                    20
                                                            GLOBAL BIODIESEL OUTLOOK
                                                                                                                                                  ASSUMPTION
                                                                                                                       18
           BILLIONS OF GALLONS




                                                                                                                            MILLIONS OF ACRES
                                 3.5
                                                                                                                       16
                                                                                                                                                  • In EU, biodiesel to
                                  3
                                                                                                                       14
                                                                                                                                                    represent 5% of
                                 2.5                                                                                   12
                                                                                                                                                    transport fuels with
                                  2                                                                                    10
                                                                                                                                                    U.S. growing up to 2%
                                                                                                                       8
                                 1.5
                                                                                                                       6
                                  1
                                                                                                                       4
                                 0.5                                                                                   2
                                  0                                                                                    0
                                        2005     2006       2007        2008      2009    2010     2011        2012

                                                            BIODIESEL                       PALM
                                                                                            SOYBEAN
                                                            RAPESEED & CANOLA

                                                                                                                                                                            20
Source: Proexporter Network, Pro Mar And Monsanto Estimates
BIOTECHNOLOGY

   MaveraTM High-Value Corn with Lysine to Provide
   Incremental Value to Both Feed and Fuel Markets
                                                                                 KEY MARKET ACRES       U.S.     BRAZIL   ARGENTINA

                       Renessen’s MaveraTM High-                                 AVAILABLE MARKET        5M       2M         1M

                       Value Corn with Lysine                                    PERCENT PENETRATED      0%       0%         0%


                                                             HIGH-VALUE CORN WITH LYSINE IN THE FIELD
              R&D Pipeline                                                        FIELD TRIAL PHOTOS FROM 2006

     Mavera High-Value Corn with
               Lysine                                LOCATION:
                                                       Monmouth, Illinois
  SITUATION:
                                                     ACTIVITY:
                            On Track
           2006 STATUS:                                Renessen researchers
                                                       check performance
  • Hybrid performance including                       indicators such as plant
    yield and nutrient composition                     height, chlorophyl and
                                                       ear fill. They also use
    will be shared in January
                                                       advanced crop analytics
  VALUE CONSIDERATIONS                                 to help track the oil levels
                                                       in plants
  • Enhances level of limiting
                                                     OBSERVATIONS:
    essential amino acids and corn
    oil content in feed, and lowers                    U.S. received regulatory
                                                       approval in 2006;
    cost of animal rations
                                                       Agronomic testing in the
  • Incremental value extracted
                                                       field to select best
    through Renessen’s Corn                            hybrids
    Processing Technology
             RETAIL
                          <$10/acre1
         VALUE/ACRE:

       TOTAL ACRE
                          <10M acres1
     OPPORTUNITY:



1Value and acres are for direct feed piece only and do not
                                                                                                                                  21
include value for processing component
RENESSEN OPPORTUNITY

Renessen’s New System Bolts Onto Conventional Dry Milling
Process and Makes More Efficient Use of Corn Seed
  RENESSEN PROCESS
        FLOW
•FOR ALL PRACTICAL           CONVENTIONAL DRY MILL PROCESS
PURPOSES, RENESSEN CORN
                             NUTRIENT
                             NUTRIENT
PROCESSING SYSTEM BOLTS
                                                           Hammer
                                                           Hammer
                              DENSE                                                              Distillation       Ethanol
                              DENSE
ONTO A CONVENTIONAL DRY                      Elevator                        Fermentation        Distillation       Ethanol
                                             Elevator                        Fermentation
                                                             Mill
                               CORN                          Mill
                               CORN
MILL PROCESS

         STEP 1:
                                                                                                     Drying
                                                                                                     Drying
•START WITH A
NUTRITIONALLY DENSE CORN       RENESSEN FRACTIONATION AND EXTRACTION PROCESS
DEVELOPED THROUGH
BIOTECH OR A
CONVENTIONAL HYBRID
                                                                                        HIGHLY
                                                                                        HIGHLY                  HIGH PROTEIN
                                                                                                     4
                                                                    3             FERMENTABLE
                                      Fractionation                               FERMENTABLE
                                      Fractionation                                                              LOW OIL DDG
         STEP 2:                                                                     FRACTION
                                                                                      FRACTION

•PROCESS IT THROUGH A
                                        High oil
                                         High oil
NOVEL PROCESS
                                        fraction
TECHNOLOGY DEVELOPED BY                  fraction
CARGILL AND RENESSEN

         STEP 3:
                                                                        Nutrient-rich
                                                                        Nutrient-rich
                                      Oil extraction
                                      Oil extraction
                                                                           meal
•DELIVER FOUR HIGH-VALUE                                                    meal
REVENUE STREAMS
     1: HIGH-OIL CORN OR
     BIODIESEL
                                          Corn oil
                                          Corn oil
     2: HIGH-VALUE SWINE
     AND POULTRY FEED
     3: HIGHLY
     FERMENTABLE STARCH
                                                                             HIGH VALUE SWINE
                                  1                                 2
                                                 HIGH OIL CORN
     4: HIGH-PROTEIN, LOW-
                                                                             AND POULTRY FEED
                                          FOR FOOD OR BIODIESEL
     OIL DDG


                                                                                                                               22
SUMMARY

                            Breeding and Biotech Come Together To Lift The Ceiling
                            on Yield

                                                           U.S. CORN YIELD
                                                 HISTORY AND PROJECTED EVOLUTION
                           200
   AVERAGE YIELD (BU/AC)




                                                   (MULTIPLE REGRESSION MODEL ANALYSIS)
                           180
                                                                                                                       MONSANTO’S
                                                                                                                       OPPORTUNITY
                           160
                           140                                                                                         The delta between what is
                                                                                                                       predicted and what is
                           120
                                                                                                                       possible is where
                           100                                                                                         opportunity lies
                            80
                                                                                                                         Molecular breeding
                            60                                                                                           boosts the genetic
                                                                                                                         potential of the seed
                                 1975    1980       1985      1990     1995      2000       2005      2010      2015
                                                                                                                         Biotech traits protect
                                                                                                                         that genetic potential
                                                       U.S. SOYBEAN YIELD                                                for more practical yield
                           55
                                                HISTORY AND PROJECTED EVOLUTION
AVERAGE YIELD (BU/AC)




                           50                                                                                            Breeding and Biotech
                                                   (MULTIPLE REGRESSION MODEL ANALYSIS)
                                                                                                                         come together to
                           45
                                                                                                                         change the curve of
                           40
                                                                                                                         yield potential
                           35
                           30
                           25
                           20
                                1975    1980       1985      1990     1995       2000       2005      2010      2015

                                                                                        USDA YIELD TREND LINE
                                               PROJECTED YIELDS WITH MOLECULAR
                                               BREEDING AND BIOTECHNOLOGY
                                                                                                                                                    23
SUMMARY

  R&D Focus Aligns With Growth Drivers to Extend Leadership
  Through 2010

                                                                                                                                SITUATION              R&D
                                                                                                             FACTOR             ANALYSIS           APPLICATION
               MONSANTO’S R&D OPPORTUNITY
                                                                                                                                                    BREEDING
                                                                                                                              Growing demand
                                                                                                             U.S. corn        pressures feed
            Application of our breeding and biotech
                                                                                                                                                     BIOTECH
            capabilities fully supports our six gross                                                                         and fuel supply
            profit drivers
                                                                                                                              Better yields
                                                                                                             International    needed to
                                                                                                                                                    BREEDING
                                                                                                             corn             improve global
               DISCOVERY          PHASE I             PHASE II
  R&D PHASE:                                                          PHASE III     PHASE IV       LAUNCH
                                                                                                                              competitiveness

                                            BREEDING                                                                          Opportunity exists
                                                                                                             Global biotech   to upgrade plant
                                                                                                                                                     BIOTECH
                                                                                      COMMERCIAL
                                                        IT PLATFORM
                                          GERMPLASM




G
                                                                        ANALYTICS
                                MARKERS




                                                                                                             traits           performance with
                     GENOMICS




                                                                                                   SEED
                                             ELITE




Germplasm                                                                                                                     traits
                                                                                                   SOLD TO
                                                                                                   FARMERS
        R                                                                                                                     Improve global
                                                                                                                                                    BREEDING
                                                                                                                              productivity
                                  BIOTECHNOLOGY                                                              Cotton
                                                                                                                              through
                                                                                                             platform
                                                                                                                              technology
                                                                                                                                                     BIOTECH
                                                                                                                              infusion

                                                                                                                              Highly fragmented
                                                                                                                                                    BREEDING
                                                                                                             Seminis          market, ready for
                                                                                                                              new technology
                                                                                                                              Deliver higher
                                                                                                                              value
                                                                                                                                                     BIOTECH
                                                                                                             R&D pipeline
                                                                                                                              technologies
                                                                                                                              faster

                                                                                                                                                               24

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Rob Fraley discusses Monsanto's R&D focus

  • 1. ROBB FRALEY CHIEF TECHNOLOGY OFFICER MONSANTO EUROPEAN INVESTOR DAY November 10, 2006 1
  • 2. OVERVIEW R&D Focus Aligns With Growth Drivers to Extend Leadership Through 2010 SITUATION R&D FACTOR ANALYSIS APPLICATION MONSANTO’S R&D OPPORTUNITY BREEDING Growing demand U.S. corn pressures feed Application of our breeding and biotech BIOTECH capabilities fully supports our six gross and fuel supply profit drivers Better yields International needed to BREEDING corn improve global DISCOVERY PHASE I PHASE II R&D PHASE: PHASE III PHASE IV LAUNCH competitiveness BREEDING Opportunity exists Global biotech to upgrade plant BIOTECH COMMERCIAL IT PLATFORM GERMPLASM G ANALYTICS MARKERS traits performance with GENOMICS SEED ELITE Germplasm traits SOLD TO FARMERS R Improve global BREEDING productivity BIOTECHNOLOGY Cotton through platform technology BIOTECH infusion Highly fragmented BREEDING Seminis market, ready for new technology Deliver higher value BIOTECH R&D pipeline technologies faster 2
  • 3. OVERVIEW Farmers Buy Yield; Our R&D Approach Oriented Around Meeting That Customer Need R&D APPROACH PERCENT OF GENETIC YIELD GENETIC POTENTIAL FARM APPROACH GAIN PRESERVED = X Farmer’s Purchase Inherent yield possible from the seed Amount of yield potential Decision BREEDING GERMPLASM protected = SEED • Starting point of all agriculture; farmers maximize genetics in seed for yield • 60% of farmers select • Germplasm library • >2,000 genetic seed first, then • Monsanto is only assembled from markers used by decide on biotech company to develop 36 programs in 12 traits breeders for corn and commercialize countries X today complete above- • >100 breeding • 50% of breeding ground, below-ground research centers population comes insect-control and worldwide from inter-company, TECHNOLOGY weed-control traits inter-country crosses • Technology is used to protect and maximize • Molecular breeding yield potential of seed improves genetic potential by 2X versus conventional breeding 3
  • 4. BREEDING Monsanto’s Global Breeding Engines Deliver Yield Advantages Over Best-in-Class Competitors 2006 PRELIMINARY U.S. COMPETITIVE CORN YIELD COMPARISON 200 DEKALB U.S. Corn 195 SITUATION: COMPETITORS • Top 3 purchase drivers for BUSHELS/ACRE farmers buying DEKALB 190 corn seed all relate to performance of underlying 185 germplasm OUTLOOK: • Preliminary yield data 180 from 2006 indicates continued yield advantage 175 versus best-in-class competitors • Final data will be shared in 170 RELATIVE MATURITIES (DAYS) January 115 95 100 105 110 YIELD ADVANTAGE In 2006, across the 110-day maturity zone that covers one-third of U.S. corn production, DEKALB outperformed the competition by roughly 11 bushels per acre on average 4
  • 5. BREEDING Best Combination of Germplasm and Traits Delivers Best Yield FOCUS: YIELD PER ACRE (PRELIMINARY) U.S. Corn 194 YieldGard 200 SITUATION: bu/ac Rootworm or BUSHELS PER ACRE 182.4 • In 2006, across four states and YieldGard Plus 190 bu/ac 267 locations, DEKALB seed Herculex® with YieldGard Rootworm or 180 Rootworm or YieldGard Plus outperformed Herculex XTRA 170 competitive seed and trait performance by roughly 10 160 bu/ac on average • In 2006, across 81 locations, 150 DEKALB PIONEER statistically there is no difference between the performance of YieldGard Rootworm or YieldGard Plus FOCUS: TRAIT PERFORMANCE - ROOT PROTECTION (PRELIMINARY) and competitive traits 0.25 YieldGard Rootworm Difference between two traits OUTLOOK: NODE INJURY SCALE or YieldGard Plus statistically insignificant 0.20 • Farmers make their seed Herculex® .20 purchase decision on the total Rootworm or .17 0.15 Herculex XTRA system performance of the seed-and-trait package versus 0.10 the trait or germplasm individually 0.05 0.00 PIONEER DEKALB 5
  • 6. BREEDING Breeding Advances in France Fuel Market Share Growth CORN GRAIN HYBRID International Corn REGISTRATION – FRANCE SITUATION: 2003 - 2005 • From 2003 – 2005, Monsanto led the way with 36 new corn grain hybrids 60 or 19% of the total new 51 product entrants approved 50 in France 40 • DEKALB market share has 35 29 grown 5 points over last 30 two years • For first time ever, 20 15 12 13 11 DEKALB is co-leading 6 10 brand in France 6 4 2 2 OUTLOOK: 0 MONSANTO PIONEER SYNGENTA ALL OTHER • Yield data will be shared in January 2003 2004 2005 • Corn grain hybrid registration in France will BREEDING ACCELERATION be updated From 2003 – 2005, Monsanto registered more hybrids than its primary competitors across broadest growing regions, accounting for 19% of all newly registered hybrids in France 6
  • 7. BREEDING Corn Market Share Gains Still To Fully Reflect Power of Molecular Breeding Application MOLECULAR-BREEDING HYBRIDS AS A PERCENT OF BRANDED U.S. and UNITS SOLD IN COMMERCIAL 20% International Corn 2006 BRANDED U.S. CORN PORTFOLIO 12% MARKET SHARE: 19% IN COMMERCIAL CORN PORTFOLIO PERCENT OF BRANDED UNITS SOLD SITUATION: 10% • Conventional breeding 15% U.S. MARKET SHARE improves genetic gain on average by 1.5% per 8% year 10% DEKALB AND ASGROW OUTLOOK: 6% U.S. BRAND MARKET SHARE • Molecular breeding improves genetic 4% 5% potential by 2X versus conventional breeding 2% • By 2010, over 12% of commercial portfolio will 0% 0% be derived from molecular breeding 2001 2002 2003 2004 2005 2006 2007F 2008F 2009F 2010F CYCLE 1: CYCLE 2: CYCLE 3: INTEGRATION OF APPLICATION OF MAB SELECTION POWER OF GLOBAL GERMPLASM TO SELECTION MOLECULAR BREEDING • BY 2006, FIRST MOLECULAR • ASSEMBLED 36 MAJOR • PREDICTIVE BREEDING HYBRIDS ENTER CORN BREEDING COMBINATIONS ALLOW U.S. COMMERCIAL PROGRAMS IN 12 MORE EFFICIENT PROGRESSION PORTFOLIO COUNTRIES BREEDING OF BREEDING TECHNOLOGY • EU IS ROUGHLY 2 YEARS • FIRST INTRA-COMPANY • APPLY MOLECULAR IN THE BEHIND THE U.S. FOLLOWED CROSSES BREEDING TO TROPICAL COMMERCIAL BY LATIN AMERICA AND ASIA MARKETS, SUCH AS PORTFOLIO PACIFIC BRAZIL AND ASIA 7
  • 8. BREEDING Seminis R&D to Focus on Top Five Crops Supported by Molecular Marker Platforms TOP 5 CROPS Seminis STRATEGIC FOCUS INVESTMENTS SITUATION: • Consumer benefits such as • In 2006, narrowed flavor and seedless • Advance Tomato commercial focus to 25 molecular markers • Grower benefits such as disease crops that generate resistance most profit • Consumer benefit traits such as • Advance OUTLOOK: Sweet pepper molecular markers shape, sweetness and color • Significant marker platforms to support • Novel flavor for consumers advancements in quality • Increase breeding • Grower yield through hybrid and consumer traits for investments in Hot pepper conversion and disease top 5 crops NAFTA resistance • Advance • Consumer benefits such as molecular markers firmness, sugars, shelf life and Melon • Strengthen flavor germplasm • Strengthen • Aggressive hybrid conversion for germplasm yield and uniformity Onion • Advance • Reduce pungency for consumers molecular markers 8
  • 9. BREEDING Genetic Mapping Timetable Supports Commercial Launches of Molecular Breeding Hybrids by End of Decade MARKER PLATFORMS MARKER APPLICATION FOR KEY CROPS (2006-2009) Seminis SITUATION: 5,000 SWEET CORN • Began application of NUMBER OF MARKERS DEVELOPED breeding technology, with genome-wide marker platform for tomatoes and peppers • Melons, watermelons TARGET: 1,000 and brassica family of 1,000 markers cabbage, broccoli and cauliflower next OUTLOOK: BRASSICA • By 2009, Seminis 500 TOMATO should have 1,000+ MELON markers for 9 crops WATERMELON PEPPER ONION, CUCUMBER, LETTUCE 2009F 2007F 2008F Current Status 9
  • 10. BIOTECHNOLOGY Top-Ten Traits Poised to Deliver Significant Value PIPELINE VALUE: TOP-TEN PROJECTS REFLECTING COMMERCIAL VALUE1 VALUE PER ACRE CORE PHASE SOURCE OF VALUE ACRE BASE MARKETS Renessen Corn Processing System U.S 4 Brazil $10 - $30 20M and Mavera™ High-Value Corn with Feed and fuel Europe Lysine2 U.S. HIT 3 Roundup RReady2Yield soybeans $10 - $30 155M Brazil Yield enhancement Argentina 3 Omega-3 soybeans >$30 5M U.S. Improved health U.S. 3 YieldGard VT PRO $10 - $30 41M Brazil Insect protection 2 -GEN YIELDGARD CORN BORER nd Europe U.S 2 HIT Water replacement Drought-tolerant corn $10 - $30 164M Brazil and yield Europe HIT 2 U.S. Vistive III soybeans $10 - $30 12-15M Improved health U.S. 2 Higher yielding soybeans $10 - $30 155M Brazil Yield enhancement Argentina 2 Brazil Yield and insect Insect-protected soybeans $20 - $40 95M WITH ROUNDUP RREADY2YIELD Argentina protection U.S. 1 India Water replacement Drought-tolerant cotton $10 - $30 36M Brazil and yield Australia U.S 1 Nitrogen replacement Nitrogen utilization corn $10 - $30 164M Brazil and yield Europe 1. Top ten not presented in ranked 2. Value and acres are for direct order; Commercial value feed piece only and do not calculated by penetration and include value for Renessen’s corn retail value during three-year processing system, which is to be span at peak. determined 10
  • 11. BIOTECHNOLOGY Roundup RReady2Yield Soybeans Offer Yield Improvement Over First-Generation Roundup Ready Soybeans KEY MARKET ACRES U.S. BRAZIL ARGENTINA Roundup RReady2Yield AVAILABLE MARKET 70M 50M 35M Soybeans PERCENT PENETRATED 0% 0% 0% P R O JE CT ROUNDUP RREADY2YIELD IN THE FIELD FIELD TRIAL PHOTOS FROM 2006 R&D Pipeline HIT Roundup Project Ready2Yield soybeans LOCATION: Stonington, Illinois SITUATION: ACTIVITY: On Track 2006 STATUS: Monsanto researchers check • Yield data from 45 trials will be performance shared in January indicators in the fields such as plant VALUE CONSIDERATIONS: height, and pod size and number • Value is additive, with target of up to 5 bushel-per-acre yield OBSERVATIONS: improvement over comparable 25 locations across the U.S. tested Roundup Ready soybeans 11,000 lines tested RETAIL $10 - $30/acre VALUE/ACRE: in 45 trials TOTAL ACRE 155M acres OPPORTUNITY: 11
  • 12. BIOTECHNOLOGY Reflecting HIT Status, Roundup RReady2Yield Soybeans Is Targeted for Monsanto’s Most Significant Commercial Launch KEY MARKET ACRES U.S. BRAZIL ARGENTINA Roundup RReady2Yield AVAILABLE MARKET 70M 50M 35M Soybeans PERCENT PENETRATED 0% 0% 0% P R O JE CT LAUNCH ACRES OF U.S. TRAITS 3 HISTORICAL COMMERCIALIZED TRAITS (1996-2006) R&D Pipeline 2.5 ACRES (IN MILLIONS) Roundup HIT AVERAGE HISTORIC 2 RReady2Yield TRAIT LAUNCH: Project 1.2M ACRES soybeans 1.5 SITUATION: 1 On Track 2006 STATUS: 0.5 • Yield data from 45 trials will be 0 shared in January SOYBEAN TRAITS COTTON TRAITS CORN TRAITS VALUE CONSIDERATIONS: Target acreage for Roundup RReady2Yield commercial • Value is additive, with target of up to 5 bushel-per-acre yield launch is expected to be a multiple above historical acreages improvement over comparable in launch years Roundup Ready soybeans RETAIL ROUNDUP RREADY2YIELD: COMMERCIAL MILESTONES $10 - $30/acre VALUE/ACRE: STARTING POINT U.S. REGULATORY TOTAL ACRE APPROVAL 155M acres OPPORTUNITY: SEASON 1 LAUNCH YEAR GLOBAL REGULATORY CLEARANCES PRE-COMMERCIAL USER-RELIABILITY COMMERCIAL LAUNCH TRIALS 12
  • 13. BIOTECHNOLOGY Tests of Drought-Tolerant Corn Continue to Validate Concept KEY MARKET ACRES U.S. BRAZIL EUROPE Drought-tolerant AVAILABLE MARKET 80M 30M 24M corn PERCENT PENETRATED 0% 0% 0% P R O JE CT DROUGHT TOLERANT CORN IN THE FIELD R&D Pipeline FIELD TRIAL PHOTOS FROM 2006 HIT Project Drought-tolerant corn SITUATION: On Track 2006 STATUS: LOCATION: • Continued expansion of testing in lead Vacaville, California ACTIVITY: genes and events in moisture-stressed Monsanto and broad acre environments researcher checks • Currently testing hundreds of genes performance across several generations of drought indicators in the traits field such as chlorophyl content, • Results will be shared in January ear size, and plant height VALUE CONSIDERATIONS: OBSERVATIONS: • Value of trait reflects better yields Confirming third under moisture-stressed conditions year of field trial • Value will be specific to variable costs data in U.S. of water use by farmers, rather than fixed costs of irrigation RETAIL $10 - $30/acre VALUE/ACRE: TOTAL ACRE 164M acres OPPORTUNITY: 13
  • 14. BIOTECHNOLOGY Multi-Generational Drought-Tolerant Corn to Create Value Across Multiple Market Segments KEY MARKET ACRES U.S. BRAZIL EUROPE Drought-tolerant AVAILABLE MARKET 80M 30M 24M corn PERCENT PENETRATED 0% 0% 0% P R O JE CT SEGMENTED VALUE OPPORTUNITY ACROSS MARKETS: EUROPE EXAMPLE R&D Pipeline HIT Project Drought Monitor Drought-tolerant corn D0: Abnormally Dry SITUATION: D1: Drought - Moderate On Track 2006 STATUS: D1: Drought - Severe D1: Drought - Extreme • Continued expansion of testing in lead genes D1: Drought - Exceptional in moisture-stressed and broad acre environments. • Currently testing hundreds of genes across several generations of drought traits Source: UCL Department of Space and Climate Physics • Results will be shared in January VALUE CONSIDERATIONS: IRRIGATED DRYLAND STABILITY • Value of trait reflects better yields under Irrigated Non-Irrigated Non-Irrigated moisture-stressed conditions; varies by Value is in Value is in Value is in region (see table at right) replacing improved yields improved yields • Value will be specific to variable costs of irrigation, reducing annually, by when moisture is water use by farmers, rather than fixed costs variable costs of improving water- less than optimal irrigation use efficiency of irrigation RETAIL VALUE/ACRE: $10 - $30/acre TOTAL ACRE 164M acres OPPORTUNITY: 14
  • 15. BIOTECHNOLOGY Vistive III Soybeans Have Potential To Leapfrog on Commercial Development Track KEY MARKET ACRES U.S. Vistive III Soybeans AVAILABLE MARKET 12-15M PERCENT PENETRATED 0% P R O JE CT VISTIVE III FIELD TRIAL PHOTOS FROM 2006 R&D Pipeline HIT Vistive III Soybeans Project SITUATION: LOCATION: On Track 2006 STATUS: Sperry, Iowa ACTIVITY: • Field trial results on oil composition 2006 summer and oil yield will be reviewed in agronomic January testing VALUE CONSIDERATIONS: OBSERVATIONS: • Approximately 40M acres of U.S. First broad acre soybean crop is crushed for oil; field testing in U.S. with lead Vistive III is optimal for non- events hydrogenated and hydrogenated- frying segments • Vistive III has potential to be priced at a premium to conventional soybean oil RETAIL VALUE/ACRE: $10 - $30/acre TOTAL ACRE 12M - 15M acres OPPORTUNITY: 15
  • 16. BIOTECHNOLOGY Vistive III Soybeans Meet Multiple Needs in Food Industry KEY MARKET ACRES U.S. AVAILABLE MARKET 12-15M Vistive III Soybeans P R O JE CT PERCENT PENETRATED 0% CONSUMER VISTIVE MARKET R&D Pipeline FAMILY OIL FOR HIT Vistive III Soybeans FRYING AND IMPROVED SOYBEAN Project SPRAYING QUALITY FOR LIQUID OILS SITUATION: Crackers Snack chips On Track 2006 STATUS: • Field trial results on oil composition and oil yield will be IMPROVING NUTRITIONAL reviewed in January PROFILE OF SOYBEAN OIL VALUE CONSIDERATIONS: LINOLENIC LINOLEIC OLEIC SATS 18:3 18:2 18:1 18:0 / 16:0 • Approximately 40M acres of U.S. STANDARD SOYBEAN soybean crop is crushed for oil; Vistive III is optimal for non- TARGET: VISTIVE III hydrogenated and hydrogenated- LOW-LIN – MID-OLEIC – LOW-SAT SOYBEANS frying segments • Vistive III has potential to be Major market segments for U.S. soybean oil priced at a premium to NON- HYDROGENATED- HYDROGENATED- HYDROGENATED FRYING BAKING conventional soybean oil RETAIL For salad oils, For various For various $10 - $30/acre VALUE/ACRE: household use frying baking TOTAL ACRE applications applications 12M – 15M acres OPPORTUNITY: Uses 50% of Uses 25% of Uses 25% of total crushing total crushing total crushing (~20M acres) (~10M acres) (~10M acres) 16
  • 17. BIOTECHNOLOGY Omega-3 Soybeans Have Met Early Development Targets for Both Food Application and Field Performance KEY MARKET ACRES U.S. Omega-3 soybeans AVAILABLE MARKET 5M PERCENT PENETRATED 0% R&D Pipeline Omega-3 soybeans OMEGA-3 OIL TASTE RESULTS FROM 2005 SITUATION: On Track STATUS: 10 TASTE RATING • Extensive field testing for 5 lead events in U.S. 0 • Food formulation results will Omega-3 be shared in January Soy Oil SDA Oil Fish Oil VALUE CONSIDERATIONS: • Value created through a Taste Rating 0-15 Scale product with similar profile Score of zero indicates no flavor to soybean oil in taste, shelf- life and oil stability but with In taste-testing, Omega-3 oil containing a superior nutritional and stearidonic acid (SDA) oil compares taste profile to fish oil favorably versus fish oil and commodity RETAIL Salad Dressing soy oil >$30/acre VALUE/ACRE: with SDA Oil Testing also focused on field performance, TOTAL ACRE demonstrating Omega-3 soybean yield on 5M acres OPPORTUNITY: par with commodity soybeans – an important factor to farmers growing specialty crops 17
  • 18. BIOTECHNOLOGY Early Field Testing Indicates Nitrogen Utilization Corn Offers Yield Benefits in Both Limited and Normal Nitrogen Conditions KEY MARKET ACRES U.S. BRAZIL EUROPE Nitrogen utilization corn AVAILABLE MARKET 80M 30M 24M PERCENT PENETRATED 0% 0% 0% NITROGEN CONTROL TESTING R&D Pipeline Nitrogen utilization corn SITUATION: LOCATION: On Track STATUS: Morrisonville, Illinois and • Continued expansion of Jerseyville, Illinois ACTIVITY: testing in limited and normal Field control nitrogen environments testing to measure • Results will be shared in nitrogen uptake January and to screen genes for nitrogen VALUE CONSIDERATIONS: utilization • Value created through OBSERVATIONS: improved yield in both Under normal limited and normal nitrogen nitrogen, corn has environments good chlorophyll content, normal RETAIL $10 - $30/acre VALUE/ACRE: ear development and higher yield TOTAL ACRE 164M acres OPPORTUNITY: Limited Nitrogen Normal Nitrogen 18
  • 19. BIOTECHNOLOGY Nitrogen Utilization Technology Extends Benefits Across Crop Families KEY MARKET ACRES U.S. CANADA EUROPE Nitrogen utilization canola AVAILABLE MARKET 1-2M 12-14M 12-14M PERCENT PENETRATED 0% 0% 0% 2006 NITROGEN R&D Pipeline CANOLA CONTROL TESTING Nitrogen utilization canola SITUATION: 1800 On Track STATUS: 1700 • Continued expansion of testing in limited and normal YIELD (LBS/ACRE) 1600 nitrogen environments NITROGEN UTILIZATION 15% 9% • Results will be shared in CANOLA 1500 OBSERVATIONS: 16% January Significant increase in pod 11% development 1400 VALUE CONSIDERATIONS • Value created through 1300 improved yield in both 18% limited and in normal 1200 nitrogen environments RETAIL $10 - $30/acre 1100 VALUE/ACRE: 0 50 100 150 200 TOTAL ACRE 25-30M acres OPPORTUNITY: NITROGEN APPLIED (LBS/ACRE) CANOLA CONTROL Conventional use rate OBSERVATIONS: Nitrogen gene Significantly less pod activity Control 19
  • 20. BIOTECHNOLOGY Opportunity in Renewable Fuels Is Driving Yield Demand in Agriculture U.S. & BRAZIL ETHANOL OUTLOOK ETHANOL 30 45 ASSUMPTION BILLIONS OF GALLONS 40 MILLIONS OF ACRES 25 • MTBE replacement by 35 2010 is base case 20 30 • Incremental yield 25 gains through 15 20 technological 10 15 innovations allow further substitution 10 5 5 0 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 CORN U.S. SUGAR CANE BRAZIL BIODIESEL 4 20 GLOBAL BIODIESEL OUTLOOK ASSUMPTION 18 BILLIONS OF GALLONS MILLIONS OF ACRES 3.5 16 • In EU, biodiesel to 3 14 represent 5% of 2.5 12 transport fuels with 2 10 U.S. growing up to 2% 8 1.5 6 1 4 0.5 2 0 0 2005 2006 2007 2008 2009 2010 2011 2012 BIODIESEL PALM SOYBEAN RAPESEED & CANOLA 20 Source: Proexporter Network, Pro Mar And Monsanto Estimates
  • 21. BIOTECHNOLOGY MaveraTM High-Value Corn with Lysine to Provide Incremental Value to Both Feed and Fuel Markets KEY MARKET ACRES U.S. BRAZIL ARGENTINA Renessen’s MaveraTM High- AVAILABLE MARKET 5M 2M 1M Value Corn with Lysine PERCENT PENETRATED 0% 0% 0% HIGH-VALUE CORN WITH LYSINE IN THE FIELD R&D Pipeline FIELD TRIAL PHOTOS FROM 2006 Mavera High-Value Corn with Lysine LOCATION: Monmouth, Illinois SITUATION: ACTIVITY: On Track 2006 STATUS: Renessen researchers check performance • Hybrid performance including indicators such as plant yield and nutrient composition height, chlorophyl and ear fill. They also use will be shared in January advanced crop analytics VALUE CONSIDERATIONS to help track the oil levels in plants • Enhances level of limiting OBSERVATIONS: essential amino acids and corn oil content in feed, and lowers U.S. received regulatory approval in 2006; cost of animal rations Agronomic testing in the • Incremental value extracted field to select best through Renessen’s Corn hybrids Processing Technology RETAIL <$10/acre1 VALUE/ACRE: TOTAL ACRE <10M acres1 OPPORTUNITY: 1Value and acres are for direct feed piece only and do not 21 include value for processing component
  • 22. RENESSEN OPPORTUNITY Renessen’s New System Bolts Onto Conventional Dry Milling Process and Makes More Efficient Use of Corn Seed RENESSEN PROCESS FLOW •FOR ALL PRACTICAL CONVENTIONAL DRY MILL PROCESS PURPOSES, RENESSEN CORN NUTRIENT NUTRIENT PROCESSING SYSTEM BOLTS Hammer Hammer DENSE Distillation Ethanol DENSE ONTO A CONVENTIONAL DRY Elevator Fermentation Distillation Ethanol Elevator Fermentation Mill CORN Mill CORN MILL PROCESS STEP 1: Drying Drying •START WITH A NUTRITIONALLY DENSE CORN RENESSEN FRACTIONATION AND EXTRACTION PROCESS DEVELOPED THROUGH BIOTECH OR A CONVENTIONAL HYBRID HIGHLY HIGHLY HIGH PROTEIN 4 3 FERMENTABLE Fractionation FERMENTABLE Fractionation LOW OIL DDG STEP 2: FRACTION FRACTION •PROCESS IT THROUGH A High oil High oil NOVEL PROCESS fraction TECHNOLOGY DEVELOPED BY fraction CARGILL AND RENESSEN STEP 3: Nutrient-rich Nutrient-rich Oil extraction Oil extraction meal •DELIVER FOUR HIGH-VALUE meal REVENUE STREAMS 1: HIGH-OIL CORN OR BIODIESEL Corn oil Corn oil 2: HIGH-VALUE SWINE AND POULTRY FEED 3: HIGHLY FERMENTABLE STARCH HIGH VALUE SWINE 1 2 HIGH OIL CORN 4: HIGH-PROTEIN, LOW- AND POULTRY FEED FOR FOOD OR BIODIESEL OIL DDG 22
  • 23. SUMMARY Breeding and Biotech Come Together To Lift The Ceiling on Yield U.S. CORN YIELD HISTORY AND PROJECTED EVOLUTION 200 AVERAGE YIELD (BU/AC) (MULTIPLE REGRESSION MODEL ANALYSIS) 180 MONSANTO’S OPPORTUNITY 160 140 The delta between what is predicted and what is 120 possible is where 100 opportunity lies 80 Molecular breeding 60 boosts the genetic potential of the seed 1975 1980 1985 1990 1995 2000 2005 2010 2015 Biotech traits protect that genetic potential U.S. SOYBEAN YIELD for more practical yield 55 HISTORY AND PROJECTED EVOLUTION AVERAGE YIELD (BU/AC) 50 Breeding and Biotech (MULTIPLE REGRESSION MODEL ANALYSIS) come together to 45 change the curve of 40 yield potential 35 30 25 20 1975 1980 1985 1990 1995 2000 2005 2010 2015 USDA YIELD TREND LINE PROJECTED YIELDS WITH MOLECULAR BREEDING AND BIOTECHNOLOGY 23
  • 24. SUMMARY R&D Focus Aligns With Growth Drivers to Extend Leadership Through 2010 SITUATION R&D FACTOR ANALYSIS APPLICATION MONSANTO’S R&D OPPORTUNITY BREEDING Growing demand U.S. corn pressures feed Application of our breeding and biotech BIOTECH capabilities fully supports our six gross and fuel supply profit drivers Better yields International needed to BREEDING corn improve global DISCOVERY PHASE I PHASE II R&D PHASE: PHASE III PHASE IV LAUNCH competitiveness BREEDING Opportunity exists Global biotech to upgrade plant BIOTECH COMMERCIAL IT PLATFORM GERMPLASM G ANALYTICS MARKERS traits performance with GENOMICS SEED ELITE Germplasm traits SOLD TO FARMERS R Improve global BREEDING productivity BIOTECHNOLOGY Cotton through platform technology BIOTECH infusion Highly fragmented BREEDING Seminis market, ready for new technology Deliver higher value BIOTECH R&D pipeline technologies faster 24