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Kansas
•    Area, 82K sq. miles; Population, 2.9M

•    1 medical school, KUMC, Kansas City

•    3 campuses awarding doctorates in biomedical science

The Kansas IDeA Program
•    7 COBRES focus on specific research areas

•    1 INBRE focuses on infrastructure

     ALL INVESTIGATOR-INITIATED

    Goal: To increase Kansas biomedical research
          capacity
Kansas IDeA Program Management

Mandated Oversight
        Federal: NCRR (1998 – 2011); NIGMS (2011-2012)
        Internal and External Advisory Committees
                 AAAS Review Committee (K-INBRE)
                 Project Steering Committees
                 Annual reports:, NIGMS
Other Reporting
                 Kansas Board of Regents
                 Kansas IDeA Committee
                 Campus research administrators
                 Industry and philanthropic funding sources
Kansas IDeA Committee Oversight
         P.I.s of Kansas COBREs and INBRE, meet semi-annually
         Facilitates: state relationships, collaborations, PR efforts,
scientific expertise
COBRE/INBRE collaborations: building on
 Kansas strengths
                                    KU School of Pharmacy is #2 in
                                    the nation in NIH funding


                                        Outcomes:

                                        Founding of IAMI (2010) Institute for
                                        Advancement of Medical Innovation

                                        Kauffman Foundation $8 M + KU
                                        Endowment match (2010) for IAMI

                                        Kansas CTSA (2011-2016), Clinical
COBRE Experimental Therapeutics         Translational Service Award
  KU-Lawrence, 2000-2015                K-INBRE supported
  P.I.s:Timmermann/Georg
                                        KUMC now an official NCI Cancer
Major core: High throughput screening   Center (2012-2017)
  for drug discovery and development    K-INBRE supported
BUILDING ON KANSAS STRENGTHS




                2001-2014
The Kansas INBRE Structure and
         Organization (2001-2014)
   P.I.s: Wright/Hunt; Area: Cell and Developmental Biology

                          Total NIH funding, $45.4 M
                          Other funding, $3.02M
                           institutional, state government, industry




10 sites, all with
some strength in
Cell and Developmental
Biology
Communications:        Director, R. Spaulding
& Director, KUMC Center for Telemedicine & Telehealth
 *Modeled after KUMC medical outreach

 *All campuses linked through high definition (HD)
 videoconference equipment for education and
 communications; Bioinformatics a major user

 *Websites for both IDeA and K-INBRE;
 Facebook; notification of meetings,
 workshops

 *Faculty and student features

 *Periodic publication of Kansas IDeAs
 and brochures
Faculty: Awards Chair, D. Abrahamson
Competitive awards:           external reviews (AAAS/AIBS)
                              criteria: strength of science & relationship
                              to Cell and Developmental Biology

     *73 recruitment packages (1/recruit, $25 - $50K)
     *19 new investigator grants (2.5 yr, $250K, mentored)
     *88 pilot grants (1 yr, $40K)
     *34 bridging grants (1 yr, $40K)
     *64 Faculty Scholar awards (1 yr, $10-20K)

    Return on 278 investments: 5:1
     total investment, $13,162,000; new external grants, $64,133,000

Other benefits:      -linked audiovisual conferencing equipment
                     -symposia (local, regional and national)
                      -access to bioinformatics and all other IDeA cores
Students: Director, K. Chapes, KSU
Undergraduates:
   43   Star Trainees
        Return on investment: 87% go on to graduate training
   688 Summer/Semester Scholars
        Return on investment: 68% go into biomedical fields
   1060 Presented research at IDeA national meetings (60) and Annual
        Symposia (~1000)

   “A life-changing event…”
Post-Docs:
 *1 yr post-doc support
 *2 yr partnerships for translational research

All: access to IDeA cores & mentoring
2011



2011 K-INBRE Symposium
     Poster Session
BUILDING ON KANSAS STRENGTHS




                2001-2014
K-INBRE: Outcomes on $48.4M investment

Communication: Improved dissemination of knowledge
                 Improved collaborations
Technology:     First bioinformatics facility in Kansas (3 campus cores)
                Restructuring for increased medical informatics
Faculty:        Increased NIH funding, $43.8M (2001) to $106.5M (2011)
Students:       Broadened research participation, rural populations
                NIH-level research infrastructure initiated on 7 campuses
For the State of Kansas:
Workforce:      Financed research training for 731 undergraduates
                Numerous post-docs and new investigators
Kansas biomedical industry:       871 new jobs
                                  Growing at double the national rate
-
Total NIH funds for the State of Kansas (red line) and
total IDeA funds for the State of Kansas (blue bars) rise
                   and fall in concert
Successful Competition
  for NIH funds is, in IDeA
states, related to allocations
   from the IDeA program

   Above: levels of NIH funding to
   KUMC parallel levels of funding
   awarded to KUMC under the IDeA
   program

   Below: levels of NIH funding to
   all IDeA states parallel levels of
   funding awarded under the IDeA
   program.
Joan Hunt

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Joan Hunt

  • 1. Kansas • Area, 82K sq. miles; Population, 2.9M • 1 medical school, KUMC, Kansas City • 3 campuses awarding doctorates in biomedical science The Kansas IDeA Program • 7 COBRES focus on specific research areas • 1 INBRE focuses on infrastructure ALL INVESTIGATOR-INITIATED Goal: To increase Kansas biomedical research capacity
  • 2. Kansas IDeA Program Management Mandated Oversight Federal: NCRR (1998 – 2011); NIGMS (2011-2012) Internal and External Advisory Committees AAAS Review Committee (K-INBRE) Project Steering Committees Annual reports:, NIGMS Other Reporting Kansas Board of Regents Kansas IDeA Committee Campus research administrators Industry and philanthropic funding sources Kansas IDeA Committee Oversight P.I.s of Kansas COBREs and INBRE, meet semi-annually Facilitates: state relationships, collaborations, PR efforts, scientific expertise
  • 3. COBRE/INBRE collaborations: building on Kansas strengths KU School of Pharmacy is #2 in the nation in NIH funding Outcomes: Founding of IAMI (2010) Institute for Advancement of Medical Innovation Kauffman Foundation $8 M + KU Endowment match (2010) for IAMI Kansas CTSA (2011-2016), Clinical COBRE Experimental Therapeutics Translational Service Award KU-Lawrence, 2000-2015 K-INBRE supported P.I.s:Timmermann/Georg KUMC now an official NCI Cancer Major core: High throughput screening Center (2012-2017) for drug discovery and development K-INBRE supported
  • 4. BUILDING ON KANSAS STRENGTHS 2001-2014
  • 5.
  • 6. The Kansas INBRE Structure and Organization (2001-2014) P.I.s: Wright/Hunt; Area: Cell and Developmental Biology Total NIH funding, $45.4 M Other funding, $3.02M institutional, state government, industry 10 sites, all with some strength in Cell and Developmental Biology
  • 7. Communications: Director, R. Spaulding & Director, KUMC Center for Telemedicine & Telehealth *Modeled after KUMC medical outreach *All campuses linked through high definition (HD) videoconference equipment for education and communications; Bioinformatics a major user *Websites for both IDeA and K-INBRE; Facebook; notification of meetings, workshops *Faculty and student features *Periodic publication of Kansas IDeAs and brochures
  • 8. Faculty: Awards Chair, D. Abrahamson Competitive awards: external reviews (AAAS/AIBS) criteria: strength of science & relationship to Cell and Developmental Biology *73 recruitment packages (1/recruit, $25 - $50K) *19 new investigator grants (2.5 yr, $250K, mentored) *88 pilot grants (1 yr, $40K) *34 bridging grants (1 yr, $40K) *64 Faculty Scholar awards (1 yr, $10-20K) Return on 278 investments: 5:1 total investment, $13,162,000; new external grants, $64,133,000 Other benefits: -linked audiovisual conferencing equipment -symposia (local, regional and national) -access to bioinformatics and all other IDeA cores
  • 9. Students: Director, K. Chapes, KSU Undergraduates: 43 Star Trainees Return on investment: 87% go on to graduate training 688 Summer/Semester Scholars Return on investment: 68% go into biomedical fields 1060 Presented research at IDeA national meetings (60) and Annual Symposia (~1000) “A life-changing event…” Post-Docs: *1 yr post-doc support *2 yr partnerships for translational research All: access to IDeA cores & mentoring
  • 10. 2011 2011 K-INBRE Symposium Poster Session
  • 11. BUILDING ON KANSAS STRENGTHS 2001-2014
  • 12. K-INBRE: Outcomes on $48.4M investment Communication: Improved dissemination of knowledge Improved collaborations Technology: First bioinformatics facility in Kansas (3 campus cores) Restructuring for increased medical informatics Faculty: Increased NIH funding, $43.8M (2001) to $106.5M (2011) Students: Broadened research participation, rural populations NIH-level research infrastructure initiated on 7 campuses For the State of Kansas: Workforce: Financed research training for 731 undergraduates Numerous post-docs and new investigators Kansas biomedical industry: 871 new jobs Growing at double the national rate -
  • 13. Total NIH funds for the State of Kansas (red line) and total IDeA funds for the State of Kansas (blue bars) rise and fall in concert
  • 14. Successful Competition for NIH funds is, in IDeA states, related to allocations from the IDeA program Above: levels of NIH funding to KUMC parallel levels of funding awarded to KUMC under the IDeA program Below: levels of NIH funding to all IDeA states parallel levels of funding awarded under the IDeA program.