1. 1. Secretion of what gastrointestinal C. 0%
hormones will be primarily decreased as a D. 100%
result of iduodenum removal? E. 75%
A. Histamine 7. Scraps of the mycelium of a fungus, spores,
B. Gastrin and histamine air bubbles and fat drops were discovered
C. Cholecystokinin and secretin on microscopy of the patient's hair excluded
D. Gastrin from the infected areas. What fungus disease
E. Neurotensin is characterised by this microscopic picture?
2. Low level of albumins and fibrinogen was A. Sporotrichosis
detected in the patient's blood. Decreased B. Favus
activity of what organelle of the liver C. Epidermophytosis
hepatocytes can most probably cause it? D. Trichophytosis
A. Granular endoplasmatic reticulum E. Microspory
B. Lysosomes 8. From the nasopharynx of a 5-year-old child
C. Golgi complex it was excreted a microorganism which
D. Mitochondrions is identical to Corynebacterium diphtheriae
E. Agranular endoplasmatic reticulum dose according to morphological and biochemical
3. A 10-year-old girl often experiences acute signs. But this microorganism
respiratory infections with multiple punctate does not produce exotoxin. As a result
haemorrages in the places of clothes friction. of what process can this microorganism
Hypovitaminosis of what vitamin has the become toxigenic?
girl? A. Growing with antitoxic serum
A. B2 B. Phage conversion
B. C C. Chromosome mutation
C. B6 D. Passing through the organism of the
D. B1 sensitive animals
E. A E. Cultivation in the telluric environment
4. Different functional groups can be 9. A patient has undergone an amputation
presented in the structure of L-amino acid's of lower extremity. Some time later painful
radicals. Identify the group that is able to nodules appeared in a slump. Amputations
form ester bond: neuromas were found out at the microscopic
A. -OH examination. To what pathological processes
B. -NH2 do those formations relate?
C. -CONH2 A. Inflammation
D. -CH3 B. Regeneration
E. -SH C. Hyperemia
5. A 27-year-old woman has dropped penicillin D. Metaplasia
containing eye drops. In a few minutes E. Dystrophy
there appeared feeling of itching, burning 10. To prevent long-term effects of 4-day
of the skin, lips and eyelids edema, whistling malaria a 42-year-old patient was prescribed
cough, decrease of BP. What imunoglobulins primaquine. On the 3-rd day from the
take part in the development of this allergic begin of treatment there appeared stomach
reaction? and heart pains, dyspepsia, general cyanosis,
A. IgM and IgG hemoglobinuria. What caused side effects of
B. lgA and IgM the preparation?
C. IgM and IgD A. Drug potentiation by other preparations
D. IgG and IgD B. Cumulation of the preparation
E. IgE and IgG C. Delayed urinary excretion of the
6. Hypertrychosis of auricles is caused by preparation
a gene that is localized in Y-chromosome. D. Decreased activity of microsomal liver
Father has this feature. What is the probability enzymes
to give birth to a boy with such anomaly? E. Genetic insufficiency of glucose 6-phosphate
A. 25% dehydrogenase
B. 35 % 11. A patient with diabetes mellitus experienced

2. loss of consciousness and convulsions after D. Balantidium
injection of insulin, what is the E. Intestinal amoeba
result of biochemical blood analysis for 16. A 44-year--old woman complains of
concentration of the sugar? common weakness, heart pain., considerable
A. 3,3 mmol/L increase of body weigt. Objectively: moonlike
B. 8,0 mmol/L face, hirsutism, AP- 165/100 mm Hg.
C. 5,5 mmol/L height- 164 cm, weight - 103 kg: fat is mostly
D. 1,5 mmol/L accumulated in the region of neck, upper
E. 10,0 mmol/L shoulder girdle, stomach. What is the main
12. A patient with complaints of dryness in pathogenetic mechanism of obesity?
the mouth, photophobia and vision impairment A. Decreased production of thyroidal
was admitted in the reception-room. hormones
Skin is hyperemic, dry, pupils, are dilated, B. Increased production of insulin
tachycardia. Poisoning with belladonna C. Decreased production of glucagon
alkaloids was diagnosed on further examination. D. Increased production of glucocorticoids
What medicine should be prescribed? E. Increased production of mineralocorticoids.
A. Armine 17. Inflammatory process or modified
B. Dipiroxim subserous layer around cervix or the uterus
C. Pilocarpine caused an intensive pain syndrome. In what
D. Diazepam region of genitals does the pathological
E. Prozerin process take place?
13. A patient suffering from trombophlebitis of A. Endometrium
the deep crural veins suddenly died. B. Perimetrium
Autopsy has shown freely lying red C. Mesometrium
friable masses with dim crirnped surface D. Parametrium
In the trunk and bifurcation of the E. Myometrium
pulmonary artery. What pathologic process 18. Microspecimen of red bone marrow
was revealed by morbid anatomist? contains multiple capillares through the
Ac. Thrombosis walls of which mature blood cells penetrate
B. Tromboembolism into the bloodstream. What type of capillares
C. Tissue embolism are these?
D. Fat embolism A. Fenestrational
E. Embolism with foreign body? B. Sinusoidal
14. A 38-year-old man who poisoned himself C. Somatical
with mercury dichloride was taken to the D. Visceral
admission room in grave condition. What E. Lymphatic
antidote should be immediately introduced? 19. A patient with thrombophlebitis of
A. Isonitrosine lower extremities had got chest pains, blood
B. Dipiroxim spitting, growing respiratory failure that
C. Unithiol caused his death. Autopsy revealed multiple
D. Nalorphine pulmonary infarctions. What is the most
E. Atropine probable reason of their development?
15. Slime, blood and protozoa 30-200 microns A. Pulmonary artery thrombosis
long have been revealed in a man's B. Bronchial artery thrombosis
feces. The body is covered with cilias and has C. Bronchial artery embolism
correct oval form with a little bit narrowed D. Pulmonary venous thrombosis
anterior and wide round shaped posterior E. Pulmonary artery embolism
end. At the anterior end a mouth is visible. 20. An isolated cell of human heart
In cytoplasm there are two nucleui and automatically generates excitation impulses
two short vacuoles. What are the described with frequency 60 times pro minute. What
features typical for? structure does this cell belong to?
A. Lamblia A. Ventricle
B. Dysenteric amoeba B. Sinoatrial node
C. Trichomonas C. Atrioventricular node

3. D. His' bundle B. Satellite-cells
E. Atrium C. Fibroblasts
21. During examination of a patient, there D. Myofibroblasts
was found a neoplasm in the white substance E. Myoblasts
of cerebral hemispheres with localization in the 26. An autopsy revealed large (1-2 cm)
knee and frontal part of posterior crus of brownish-red, easy crumbling formations
internal capsule. Fibres of what conductive covering ulcerative defects on the external
tract of' the brain will be disrupted? surface of the aortic valve. That is the most
A. Tr. frontothalamicus likely diagnosis?
B. Tr. parietooccipitopontinus A. Diffusive endocarditis
C. Tr. pyramidalis B. Fibroplastic endocarditis
D. Tr. frontopontinus C. Acute verrucous endocarditis
E. Tr. thalamocorticalis D. Polypous-ulcerative endocarditis
22. A sick man with high temperature and a E. Recurrent warty endocarditis
lot of tiny wounds on the body has been 27. A patient died from acute cardiac
admitted to the hospital. Lice have been insufficiency. The histological examination
found in the folds of his clothing. What disease of his heart revealed the necrotized section
can be suspected? in myocardium of the left ventricle, which
A. Plague was separated from undamaged tissue
B. Epidemic typhus by the zone of hyperimic vessels, small
C. Malaria hemorrhages and leukocytic infiltration.
D. Tularemia What is the most likely diagnosis?
E. Scabies A. Diffuse exudate myocarditis
23. Autopsy of a 46-year-old man revealed B. Productive myocarditis
Multiple brown-and-green layers and C. Focal exudate myocarditis
hemmorhages on the mucous membrane D. Myocardial ischemic dystrophy
of rectum and sigmoid colon; slime and E. Myocardial infarction
some blood in colon lumen; histologically 28. A patient operated on complicated
- fibrinous colitis. In course of bacteriological appendicitis has the following changes of
analysis of colon contents S.Sonne were blood count: erythrocytes – 4,0 ·1012 /1,
found. What is the most probable diagnosis? Hb - 120 gll. color index - 0.9, leukocytes
A. Crohn’s disease - 18·109 /1, basophils - 0, eosinophils - 0,
B. Cholera myelocytes - 0, juvenile - 0, stab neutrophils
C. Salmonellosis - 20, segmentonuclear neutrophils - 53,
D. Dysentery lymphocytes - 21, monocytes - 5. How is such
E. Yersiniosis nuclear shift of leukocy1ic formula called?
24. Intake of oral contraceptives containing A. Degenerative left shift
sex hormones inhibits secretion of the B. Regeneratively- degenerative
hypophysiae hormones. Secretion of which C. Hyperregenerative
of the indicated hormones is inhibited D. Right shift
while taking oral contraceptives with sex E. Regenerative left shift
hormones? 29. A tissue sample of benign tumor was
A. Somatotropic studied under the electron microscope. A lot
B. Oxytocin of small (15-20 nm) spherical bodies, consisting
C. Vasopressin of 2 unequal subunits were detected.
D. Follicle-stimulating These are:
E. Thyrotropic A. Mitochondria
25. Patient with injured muscles of the B. Smooth endoplasmic reticulum
lower extremities was admitted to the C. Ribosomes
traumatological department. Due to what D. Golgi complex
cells is reparative regeneration of the muscle E. Microtubules
fibers and restoration of the muscle function 30. A 45-year-old man applied to the
possible? trauma station because of domestic shoulder
A. Myoepithelial cells trauma. Objectively: extension, reduction

4. and pronation functions of the shoulder are dystrophic changes of parenchymatous
absent. What muscle was injured? organs, brain edema. What complication can
A. Supraspinous muscle cause such changes of serous membranes
B. Subscapular muscle and inner organs?
C. Infraspinous muscle A. Thrombopenia
D. Teres minor muscle B. DIC-syndrome
E. Teres major muscle C. Anemia
31. Kidneys of a man under examination D. Uraemia
show increased resorbtion of calcium ions and E. Sepsis
decreased resorbtion of phosphate ions. 36. In course of prophylactic medical
What hormone causes this phenomenon? examination 7-year-old boy was
A. Parathormone diagnosed to have daltonism.
B. Hormonal form D3 Parents are healthy color
C. Aldosterone vision is normal. But grandfather from the
D. Thyrocalcitonin mother’s side has the same disorder.
E. Vasopressin What is the type of inheriting of this anomaly?
32. Increased fragility of vessels, enamel and A. Incomplete domination
dentine destruction resulting from scurvy B. Autosomal - dominant
are caused by disorder of collagen maturation. C. Recessive, sex-linked
What stage of procollagen modification D. Dominant, sex-linked
is disturbed under this avitaminosis? E. Autosomal - recessive
A. Hydroxyla1ion of proline 37. A patient with encephalopathy
B. Formation of polypeptide chains was admitted to the neurological inpatient
C. Detaching of N-ended peptide department. There was revealed
D. Removal of C-ended peptide from a correlation between increasing of
procollagen encephalopathy and substances absorbed by
E. Glycosylation of hydroxylysine residues the bloodstream from the intestines. What
33. A 7-year-old girl has signs of anemia. substances that are formed in the intestines
Laboratory examination revealed pyruvate can cause endotoxemia?
kinase deficiency in erythrocytes. What A. Biotin
process disturbance plays· the main role in B. Indole
anemia deve1opment? C. Acetacetate
A. Oxidative phosphorylation D. Butyrate
B. Anaerobic glycolysis E. Ornithine
C. Tissue respiration 38. A patient with hypochromic anemia has
D. Peroxide decomposition splitting hair and loss of hair, increased nail
E. Aminoacids desamination brittling and taste alteration. What is the
34. During the endoscopy the inflammation mechanism of the development of these
of a major papilla of the duodenum and the symptoms?
disturbances of bile secretion were found. In A. Decreased production of thyroid
which part of duodenum were the problems hormones
found? B. Deficiency of vitamin A
A. Upper horizontal part C. Decreased production of parathyrin
B. Ascendant part D. Deficiency of vitamin B12
C. Bulb E. Deficiency of iron-containing enzymes
D. Lower horizontal part 39. A patient visited a dentist with complaints
E. Descendent part of redness and edema of his mouth
35. For a long time a 49-year-old woman mucous membrane in a month after dental
had suffered from glomerulonephritis which prosthesis. The patient was diagnosed with
caused death. The autopsy revealed that the allergic stornatitis. What type of allergic
size of her kidney's was 7 x 3 x 2,5 cm, weight reaction by Gell and Cumbs underlies this
65, 0 g, they were dense and small-grained. disease?
Microscopically fibrinogenous inflammlation A. Cytotoxic
of serous and mucous membranes, B. Delayed type hypersensitivity

5. C. Stimulating permeability of vessels of microcirculation
D. Immunocomplex stream, increase of their hydrodynamic
E. Anaphylactic blood pressure. Increasing of the osmotic
40. Most participants of Magellan expedition concentration and dispersity of protein
to America died from avitominosis. This structures is present in the intercellular fluid.
disease declared itself by general weakness, What kind of edema will appear in this case?
subcutaneous hemorrhages, falling of A. Colloid-osmotic
teeth, gingival hemorrhages. What is the B. Lymphogenic
name of this avitominosis? C. Mixed
A. Polyneuritis (beriberi) D. Hydrodynamic
B. Pellagra E. Membranogenic
C. Rachitis 46. A 46-year-old man complains of difficulties
D. Scurvy with nasal breathing. Mikulicz's
E. Biermer's anemia cells, accumulation of epithelioid cells,
41. A 17-year-old boy fell seriously ill body plasmocytes, lymphocytes; hyaline balls
temperature rose up to 38,5°C, there were discovered in the biopsy material of the
is cough, rhinitis, lacrimation, nasal discharges. thickened nasal mucosa. What is the most likely
What kind of inflammation is it? diagnosis?
A. Suppurative inflammation A. Meningococcal nasopharyngitis
B. Hemorrhagic inflammation B. Rhinovirus infection
C. Serous inflammation C. Virus rhinitis
D. Fibrinous inflammation D. Scleroma
E. Catarrhal inflammation E. Allergic rhinitis
42. The donor who didn't donate the blood 47. A 60-year-old patient fell ill with
for a long time was investigated with obturative jaundice as a result of malignant
IFA method. Anti-HBs antibodies were tumour of the big papillary of the duodenal.
revealed. What does positive result of IFA Lumen of what anatomical structure is
in this case mean? compressed by tumour?
A. Previous hepatitis B A. Left hepatic duct
B. Chronic hepatitis C B. Common hepatic duct
C. Chronic hepatitis B C. Right hepatic duct
D. Acute hepatitis B D. Hepatopancreatic ampulla
E. Acute hepatitis C E. Cystic duct
43. A 42-year-old man suffering from gout 48. Desulfiram is widely used in medical
has increased level of urinary acid in blood. practice to prevent alcocholism. It inhibits
Allopurinol was prescribed to decrease the aldehyde dehydrogenase. Increased
level of urinary acid. Competitive inhibitor level of what metabolite causes aversion to
of what enzyme is allopurinol? alcochol?
A.Xanthine oxidase A. Propionic aldehyde
B. Guanine deaminase B. Methanol
C. Adenosine deaminase D. Ethanol
D. Hypoxanthine phosphoribosiltransferase D. Acetaldehyde
E. Adenine phosphoribosiltransferase E. Malonyl aldehyde
44. While preparing a patient to the operation 49. An experiment proved that UV-radiated
the heart chambers' pressure was cells of patients with xeroderma
measured. In one of them the pressure pigmentosum restore the native DNA
changed during one heart cycle from 0 to structure slower than cells of healthy individuals
120 mm Hg. What chamber of heart was it? as a result of reparation enzyme
A. Left atrium defection. What enzyme helps this process?
B. Left ventricle A. Primase
C. Right ventricle B. DNA polymerase III
D. - C. DNA gyirase
E. Right atrium D. RNA ligase
45. Inflammation is characterised bv increased E. Endonuclease

6. 50. An old woman was hospitalized with A. NK-cells
acute pain, edema in the right hip joint; the B. Macrophages, monocytes
movements in the joint are limited. Which C. 0-lymphocytes
bone or part of it was broken? D. T-lymphocytes, B-lymphocytes
A. The body of the thigh bone E. Fibroblasts, T-lymphocytes, B-lymphocytes
B. Ischial bone 55. The effect of electric current on the
C. Pubic bone exitable cell caused depolarization of its
D. Condyle of the thigh membrane. Movement of what ions through
E. The neck of the thigh the membrane caused depolarization?
51. In the blood of a 26-year-old man A. HCO3-
18% of erythrocytes of the spherical, B. Ca2+
ballshaped, flat and spinous shape have been C. K+
revealed. Other erythrocytes were in form D. Cl-
of the concavo-concave disks. How is this E. Na+
phenomenon called? 56. A patient with diabetes mellitus has been
A. Pathological anisocytosis delivered in hospital in the state of
B. Pathological poikilocytosis unconsciousness. Arterial pressure is low.
C. Erytrocytosis The patient has acidosis. Point substances,
D. Physiological poikilocytosis which accumulation in the blood results in these
E. Physiological anisocytosis manifestations:
52. Testosterone and it’s analogs increase A. High fatty acids
the mass of skeletal muscles that allows to B. Amino acids
use them for treatment of dystrophy. Due to C. Ketone bodies
interaction of the hormone with what cell D. Cholesterol esters
substrate is this action caused? E. Monosaccharides
A. Membrane receptors 57. Synthesis of phospholipids is disturbed
B. Chromatin as a result fatty infiltration of liver. Indicate
C. Ribosomes which of the following substances can
D. Nuclear receptors enhance the process of methylation during
E. Proteins-activators of transcription phospholipids synthesis?
53. A 39-vear-old woman has madescence in A. Ascorbic acid
the region or mammilla, a small ulcer with B. Glucose
inflammatory hyperemia and cutaneous C. Methionine
edema. Histologic examination of tissue D. Glycerin
sampling from this area revealed in the E. Citrate
malpighian layer of thickened epidermis 58. Donor skin transplantation was
atypical cells with light and optically empty performed to a patient with extensive burns.
cytoplasm. With no intracellular bridges. On the 8-th day the graft became swollen
Such cells were also found in the orifice of and changed color; on the 11-th day graft
big mammal gland ductus. What is the most rejection started. What cells take part in this
probable diagnosis? process?
A. Epidermoid cancer A. B-lymphocytes
B. Melanocarcinoma B. Erythrocytes
C. Basal cell carcinoma C. Basophils
D. Intraductal cancer D. T-lymphocytes -
E. Paget’s disease E. Eosinophils
54. A patient with clinical signs of 59. A 38-year-old patient died during
immunodeficiency has no changes of intractable attack of bronchial asthma.
the number and functional activity of Histologic examination revealed mucus
T- and B- lymphocytes. Defect with dysfunction accumulation in bronchial lumen, a lot of
of antigen-presentation to the fat cells (labrocytes) in the wall of bronches,
immunocompetent cells was found during many of them are in the state of degranulation,
examinatio on the molecule level. Defect of there are also a lot of eosinophils. What
what cells is the most probable? pathogenesis of bronchial changes is it?

7. A. Granulomatosis C. Pus in the wound
B. Immunocomplex mechanism D. Low concentration H2O2
C. Cellular cytolysis E. Inherited insufficiency of catalase
D. Atopy 65. A patient with continious bronchopneumonia
E. Cytotoxic, cytolytic action of antibodies was admitted to the therapeutic department.
60. A 2-year-old child has got intestinal Antibiotic therapy didn't give much effect.
dysbacteriosis, which resultsed in What medication for improvement of
hemorrhagic syndrome. What is the most immune state should be added to the
likely cause of hemorrhage of the child? complex treatment of this patient?
A. Fibrinogen deficiency A. Timaline
B. Hypocalcemia B. Analgin
C. PP hypovitaminosis C. Sulfocamphocaine
D. Vitamin K deficiency D. Paracetamol
E. Activation of tissue thromboplastin E. Benadryl
61. Autopsy revealed that right lung is 66. Decreased blood supply to the organs
enlarged, solid, there are fibrin layers on causes hypoxia that activates fibroblasts
the pleura. Lung tissue is light grey color on function. Volume of what elements is
incision with muddy liqued exudates.What increased in this case?
lung disease are these symptoms typical for? A. Parenchymatous elements of an organ
A. Interstitial pneumonia B. Vessels of microcircular stream
B. Bronchopneumonia C. Lymphatic vessels
C. Croupous pneumonia D. Intercellular substance
D. Pulmonary gangrene E. Nerve elements
E. Fibrosing alveolilis 67. A doctor administered Allopurinol to a
62. Blood analysis of a patient showed signs 26-year-old young man with the symptoms
of HIV infection (human immunodeficiency of gout. What pharmacological action of
virus). Which cells does HIV-virus primarily Allopurinol ensures therapeutical effect?
affect? A. By inhibiting leucocyte migration into the joint
A. Proliferating cells (stem hematoplastic B. By general analgetic effect
cells) C. By increasing uric acid excretion
B. Specialized nervous cells (neurons) D. By general anti-inflammatory effect
C. Cells that contain receptor IgM E. By inhibiting uric acid synthesis
(B-lymphocytes) 68. Thyrotoxicosis leads to increased
D. Mast cells production of thyroidal hormones T3 and
E. Cells that contain receptor T4 (T-helpers) T1, weight loss, tachycardia, psychic
63. A 60-year-old patient has reduced excitementand so on. How do thyroidal
perception of high-frequency sounds. What hormones effect energy metabolism in the
structures' disorder of auditory analyzer mitochondrion of cells?
caused these changes? A. Disconnect oxidation and oxidative
A. Eustachian tube phosphorylation
B. Main membrane of cochlea near the oval B. Stop respiratory chain
window C. Activate oxidative phosphorylation
C. Muscles of middle car D. Stop substrate phosphorylation.
D. Main membrane of cochlea near helicotrerna E. Activate substrate phosphorylation
E. Tympanic membrane 69. A patient with rheumatoid arthritis who
64. Patient with abscess of the cut wound had been treated with indometacin has got
applied to the traumatological department. signs of gastropathy.thy. What activity of the
In order to clean the wound from the pus drug can this complication be connected with?
doctor washed it with 3% hydrogen peroxide. A. Anticyclooxygenase
Foam was absent. What caused the B. Antiserotonin
absence of the drug activity? C. Antihistamine
A. Shallow wound D. Locally irritating
R. Inherited insufficiency of erythrocyte E. Antikinine
phosphatdehydrogenase. 70. Dystrophic alterations of heart are

8. accompanied with dilation of heart cavities, A. Parathormone
decreased force of heart contractions, B. Aldosterone
increased blood volume that remains during C. Adrenalin
systole in the heart cavity, vein overfill. D. Vasopressin
What heart condition is it typiccal for? E. Auricular sodiumuretic factor
A. Myogenic dilatation 76. Intrapleural pressure of an individual is
B. Cardiac tamponade being measured. In what phase did he hold
C. Emergency stage of hyperfunction and his breath if the pressure is - 25 cm H2O?
hypertrophy A.-
D. Cardiosclerosis E. Forced expiration
E. Tonogenic dilatation C. Forced inspiration
71. A physician examined a patient and D. Quiet expiration
found inguinal hernia. Through what E. Quiet inspiration
anatomic formation does it penetrate into 77. A 37-year-old man was admitted
the skin? to the surgical department with the
A. Lacuna musculorum symptoms of acute pancreatitis: vomiting,
B. Anulus inguinalis super ficialis diarrhea, bradycardia, hypotention.
C. Canalis adductorius weakness, dehydration of the organism.
D. Anulus femoralis What medicine should be used first of all?
E. Hiatus saphenus A. No-spa
72. A 60-year-old man felt asleep after B. Etaperazine
cerebral hemorrhage for a long time. C. Ephedrine
Damage of what structure caused this state? D. Platyphylline
A. Cortex of the large hemispheres E. Contrycal
B. Hippocampus 78. The alternate usage or dichlotiazide,
C. Nuclears of the cerebral nerves etacrin acid and lasex did not influence
D. Reticular formation diuretically upon the patient with marked
E. Black substance peripheral edemata. The aldosterone rate in
73. A 25-year-old woman with red and itchy the blood is increased. Indicate which medicine
eczematoid dermatitis visits your office. She should be prescribed:
had a dental procedure one day earlier with A. Urea
administration of a local anesthetic. There B. Amilorid
were no other findings, although she indicated C. Clopamid
that she had a history of allergic reactions. D. Spironolacton
Which of the following drugs is most likely E. Mannit
involved? 79. A person has steady HR not exceeding
A. Lidocaine 40 bpm. What is the pacemaker of this
B. Cocaine person's heart rhythm?
C. Bupivacaine A. Branches of His' bundle
D. Procaine B. Purkinje's fibers
E. Etidocaine C. Atrioventricular node
74. A patient with suspicion on epidemic D. Sinoatrial node
typhus was admitted to the hospital. Some E. His' bundle
arachnids and insects have been found in his 80. A 34-year-old patient was diagnosed with
flat. Which , of them, may be a carrier of the chronic glomerulonephritis 3 years ago.
pathogen or epidemic typhus? Edemata have developed within the last 6
A. Spiders month’s. What caused the edemata?
B. Cockroaches A. Hyperosmolarity of plasma
C. Bed-bugs B. Hyperproduction of vasopressin
D. Lice C. Proteinuria
E. Houseflies D. Liver dysfunction of protein formation
75. A person has reduced diuresis, E. Hyperaldosteronism
hypernatremia, hypokalemia. Hypersecretion 81. A 5-year-old child who often fells ill
of what hormone can cause such changes? with respiratory diseases has eczematous

9. appearances after consumption of some hyperemia and skin edema in few hours
food products, tendency to prolonged after burn. What mechanism strengthens
course of inflammatory processes. What kind destructive effect in the inflammation area?
of diathesis can be suspected in this case? A. Diapedesis of erythrocytes
A. Asthenic B. Proliferation of fibroblasts
B. Lymphohypoplastic C. Primary alteration
C. Arthritism D. Emigration of lymphocytes
D. Exudative-catharral E. Secondary alteration
E. Hemmorhagic 87. A patient's blood was analyzed and
82. An 18-year-old patient has enlarged the decreased erythrocyte's sedimentation
inguinal lymph nodes, they are painless, rate (ESR) was discovered. What disease
thickened on palpation. In the area of genital from the listed below is accompanied with
mucous membrane there is a small sized decreased ESR?
ulcer with thickened edges and A. Polycytemia
“laquer” bottom of greyish color. What is B. Myocardial infarction
the most probable diagnosis? C. Vitamin B deficiency
A. Syphilis D. Hepatitis
B. Trophic ulcer E. Splenomegaly
C. Tuberculosis 88. A considerable increase of activity of
D. Gonorrhea MB-forms of CPK (creatinephosphokinase)
E. Lepra and LDH-1 was revealed on the examination
83. A 56-year-old patient complaining of thirst of patient's blood. What is the most likely
and frequent urination was diagnosed with pathology?
diabete mellitus. Butamin was prescribed. A. Pancreatitis
How does the medicine act? B. Rheumatism
A. It relieves transport of glucose through C. Hepatitis
the cells' membranes D. Myocardial infarction
B. It stimulates β-cells of Langergans' islets E. Cholecystitis
C. It helps to absorb the glucose by the cells 89. A patient had been ill with bronchial
of the organism tissues asthma for many years and died from
D. It inhibits α-cells of Langergans" islets asthmatic fit. Histologic lung examination
E. It inhibits absorption of glucose in the revealed: lumen of bronchioles and small
intestines bronches contain a lot of mucus with some
84. A l-year-old child with symptoms of eosinophils, there is sclerosis of alveolar
muscle involvement was admitted to the septums, dilatation of alveole lumen. What
hospital. Examination revealed carnitine mechanism of development of hypersensibility
deficiency in his muscles. What process reaction took place?
disturbance is the biochemical basis of this A. Cytolysis determined by lymphocytes
pathology? B. Cytotoxic reaction
A. Actin and myosin synthesis C. Granulomatosis
B. Regulation of Ca2+ level in mitochondrion’s D. Immunocomplex reaction
C. Substrate phosphorylation E. Reagin reaction -
D. Lactic acid utilization 90. The process of heart transplantation
E. Transporting of fatty acids to mitochondrion’s determined the viability of myocardlial cells.
85. A patient with tissue trauma was taken The determination of what myocardium
a blood sample for the determination of parameter is the most important?
blood clotting parameters. Specify the right A. Rest potential of cardiomyocytes
sequence of extrinsic pathway activation: B. Heart temperature
A. IV - VIIa - Xa C. Concentration of Ca-ions in heart vessels
B. IV - VIII: TF - Xa D. Concentration of oxygen in heart vessels
C. III - VIII: TF - Xa E. Concentration of calcium-ions in myofibrils
D. III - IV - Xa 91. Part of the DNA chain turned 180 degree
E. III - VIIa - Xa as a result of gamma radiation. What type of
86. Necrosis focus appeared in the area of mutation took place in the DNA chain?

10. A. Doubling C. Autosomal dominant
B. Deletion D. X-linked dominant
C. Translocation E. X-linked recessive
D. Replication 97. A 45-year-old woman suffers from
E. Inversion seasonal allergic rhinitis caused by the
92. An individual is characterized by ambrosia blossoming. What medicine from
rounded face, broad forehead, a mongolian the stabilizer of the adipose cells group can
type of eyelid fold, flattened nasal c bridge, be used for prevention of this disease?
permanently open mouth, projecting A. Diazoline
lower lip, protruding tongue, short neck, flat B. Tavegyl
hands, and stubby fingers. What diagnosis C. Phencarol
can be put to the patient? D. Dimedrol
A. Klinefelter's syndrome E. Ketotifen
B. Supermales 98. After a serious viral infection a 3-year-old
C. Alkaptonuria child has, repeated vomiting, loss
D. Down’s syndrome of consciousness, convulsions. Examination
E. Turner's syndrome revealed hyperammoniemia. What may
93. Autopsy of a man who died from have caused changes of biochemical blood
chronic cardiovascular collapse revealed indices of this child?
"tiger heart". Sidewards of endocardium A. Inhibited activity of transamination
a yellowish-white banding can be seen; enzymes
myocardium is dull, dark-yellow. What B. Disorder of ammonia neutralization in
process caused this pathology? ornithinic cycle
A. Carbohydrate degeneration C. Disorder of biogenic amines neutralization
B. Fatty parenchymatous degeneration D. Activated processes of aminoacids
C. Amyloidosis decarboxylation
D. Hyaline degeneration E. Increased putrefaction of proteins in
E. Fatty vascular-stromal degeneratioin intestines
94. Children often have heavy nasal breathing 99. Part of alveoles of a preterm infant didn't
resulting from excessive development spread because of enhanced elastic recoil of
of lymphoid tissue of pharyngeal mucous lungs. How can this recoil be reduced?
membrane. What tonsils growth may cause A. By fluid suction from the respiratory tracts
this effect? B. By glycose introduction
A. All above mentioned tonsils C. By surfactant introduction
B. Tonsilla palatina D. By artificial pulmonary ventilation
C. Tonsilla pharyngea E. By pure oxygene inhalation
D. Tonsilla tubaria 100. A mother of a newborn complains
E. Tonsilla lingualis of her baby's constant belching with undigested
95. ATP synthesis is totaly blocked in a milk. Which developmental anomaly
cell. How will the value of membrane rest is it an evidence of?
potential change? A. Faux lupinum
A. It will disappear B. Esophageal atresia
B. First it will decrease, then increase C. Labium leporiurn
C. First it will increase, then decrease D. Anal atresia
D. It will be considerably increased E. Esophageal fistula
E. It will be slightly increased 101. During the operation on the hip joint of
96. A genetics specialist analyzed the a 5-year-old child her ligament was damaged
genealogy of a family and found that both which caused bleeding. What ligament was
males and females may have the illness, not damaged?
across all the generations, and that healthy A. Perpendicular of the acetabule
parents may have ill children. What is the B. Iliofemoral
type of illness inheritance? C. Pubofemoral
A. Y-linked D. Ischiofemoral
B. Autosomal recessive E. The head of the thigh

11. 102. When a patient with traumatic impairment E. Rifampicin
of the brain was examined, it was discovered 107. To anaesthetize the surgical treatment
that he had stopped to distinguish of burn surface, a patient was intravenously
displacement of an object on the skin. What injected a medication for short-acting
part of the brain was damaged? narcosis. 1 minute later the patient being
A. Frontal zone under anaesthesia showed increased blood
B. Occipital zone of the cortex pressure, tachycardia, increased tone of
C. Frontal central gurus skeletal muscles: reflexes remained. After
D. Posterior central gurus recovering from anaesthesia the patient
E. Parietal zone of the cortex had disorientation and visual hallucinations.
103. While having the dinner the child What medication was the patient injected?
choked and aspirated the food. Meavy A. Ketamine
cough has started, skin and mucose are B. Nitrous oxide
cyanotic, pulse is rapid, respiration is C. Diethyl ether
infrequent, expiration is prolonged. What D. Sombrevin
disorder of the external respiration has the child? E. Thiopental sodium
A Stenotic respiration 108. Healthy parents have got a fair-haired,
B. Stage of inspiratory dyspnea on asphyxia blue-eyed girl. Irritability, anxiety, sleep and
C. Stage of expiratory dyspnea on asphyxia feeding disturbance developed in the first
D. Biot's respiration months of the infant's life. Neurological
E. Alternating respiration examination revealed developmental
104. The ovary specimen colored with lag. What method of genetic investigation
hematoxylin-eosin contains a follicle, in which should be used for the exact diagnosis?
cubic-shaped follicle epithelium cells are A. Gemellary
placed in 1-2 layers, and scarlet membrane is B. Biochemical
seen around the ovocyte. Name this follicle: C. Population-statistical
A. Atretic D. Genealogical
B. Primary E. Cytological
C. Secondary 109. A large-scale reaction with
D. Mature parapertussis and pertussis diagnosticums
E. Primordial was made in order to make serological
105. A 58-year-old patient with acute cardiac diagnostics of the whooping cough. At the
insufficiency has decreased volume of daily bottom of the test-tubes with diagnosticum
urine - oliguria. What is the mechanism of of Bordetella parapertussis a granular
this phenomenon? sediment formed. What antibodies did this
A. Decreased number of functioning reaction reveal?
glomerules A. Antitoxins
B. Drop of oncotic blood pressure B. Precipitins
C. Rise of hydrostatic blood pressure 111 C. Opsonins
capillars D. Agglutinins
D. Reduced permeamility of renal filter E. Bacteriolysins
E. Decreased glomerular filtration 110. A patient, who suffers from congenital
106. A 35-year-old man under the treatment erythropoietic porphyria, has skin
for pulmonary tuberculosis has acute pain photosensitivity. The accumulation of what
onset of right big toe, swelling and lowgrade compound in the skin cells can cause it?
fever. The gouty arthritis was diagnosed A. Uroporphyrinogen 1
and high serum uric acid level B. Heme
was found. Which of the following C. Uroporphyrinogen 2
antituberculous drugs are known for D. Protoporphyrin
causing high uric acid levels? E. Coproporphyrinogen 3
A. Pyrazinamide 111. As a result of the damage of one of
B. Thiacetazone the Atomic Power Plant reactors the runout
C. Aminosalicylic acid of radioelements took place. People
D. Cycloserine in the high-radiation area were radiated

12. with approximately 250-300 r. They were have been blocked on an isolated rabbit’s
immediately hospitalized. What changes in heart. What changes in the heart's activity
the blood count would be typical for the victims? can result from it?
A. Anemia A. Heart stops in diastole
B. Lymphopenia B. Heart stops in systole
C. Thrombopenia C. Decreased hear beat rate
D. Neutropenia D. Decreased rate and force of heart beat
E. Leukopenia E. Decreased force of the contraction
112. The pulmonalis embolism has suddenly 118. Objective examination of a patient
developed in a 40-year-old patient with revealed: slender figure, big skull, highly
opened fracture of the hip. Choose the possible developed frontal region of face, short
kind of embolism: extremities. What constitutional type is it
A. Fat characteristic for?
B. Thrombus-embolus A. Muscular
C. Air B. Respiratory
D. Foreign body C. Cerebral
E. Tissue D. Digestive
113. Nowadays about 50 minor bases have E. Mixed
been found in the t-RNA structure besides 119. Blood sampling for the haematology
the main four nitrogenous bases. Choose the is recommended to carry out on an empty
minor nitrogenous base: stomach and in the morning. What changes
A. Cysteine in blood formula are possible if blood
B. Dihydrouracil sampling was carried out after food intake?
C. Uracil A. Increase of erythrocyte number
D. Cytosine B. Increase of plasm proteins
E. Adenine C. Increase of leukocyte number
114. A patient has elbow joint trauma with D. Decrease of thrombocyte number
avulsion of medial epicondyle of humerus. E. Decrease of erythrocyte number
What nerve can be damaged in this trauma? 120. 40-year-old patient complains of
A. Medial cutaneous nerve of forearm intensive heartbeats, sweating, nausea, visual
B. Cardiac cutaneous nerve impairment, arm tremor, hypertension.
C. Musculocutaneous nerve From his anamnesis: 2 years ago he
D. Radial was diagnosed with pheochromocytoma.
E. Ulnar Hyperproduction of what hormones causes
115. Diabetes mellitus causes ketosis as a the given pathology?
result of activated oxidation of fatty acids. A. Catecholamines
What disorders of acid-base equilibrium B. Aldosterone
may be caused by excessive accumulation of C. Glucocorticoids
ketone bodies in blood? D. Thyroidal hormones
A. Metabolic alkalosis E. ACTH
B. Metabolic acidosis 121. Microspecimen of spinal cord contains a
C. Any changes woun't happen nucleus that should be analyzed. lts
D. Respiratory acidosis neurons form motor endings in the skeletal
E. Respiratory alkalosis muscles. What nucleus of spinal cord is
116. A 30-vear-old woman was diagnosed meant?
with insufficiency of exocrinous function of A. Proper nucleus of the posterior horn
pancreas. Hydrolisis of what nutrients will B. Intermediate lateral nucleus
be disturbed? C. Thoracic nucleus
A. Proteins D. Proper nucleus of gray substance
B. Fats, carbohydrates E. Proper nucleus of the anterior horn
C. Proteins, carbohydrates 122. Parents with an ill child consulted
D. Proteins. fats an infectionist. They had been working in
E. Proteins, fats, carbohydrates one of Asian countries for a long time.
117. The calcium canals of cardiomyocytes The child has sallow skin, loss of appetite,

13. laxity, enlarged liver, spleen, peripheral B. Uric acid
lymph nodes. What protozoal illness can be C. Glucose
suspected? D. Common lipids
A. Balantidiasis E. Mineral salts
B. Lambliasis 128. A 50-year-old patient was injured on
C. Toxoplasmosis the occipital region of the head. The dosed
D. Visceral leishmaniasis skull trauma was diagnosed. She was taken
E. Amebiasis to the hospital. The medical examination:
123. In the specimen of one of the parts deregulation of walking and balance.
of respiratory system a tubular organ was trembling of arms. What part of brain was
found. It has low epithelium, well developed injured?
muscular tunic, glands and cartilage are A. The spinal cord
absent. Name this organ: B. The mind-brain
A. Minor bronchs C. The inter-brain
B. Major bronchs D. The cerebellum
C. Median bronchs E. The medulla oblongata
D. Trachea 129. A woman with 0 (l) blood group
E. Larynx has born a child with AB blood group.
124. A 63-year-old woman shows symptoms This woman's husband has A blood group.
of rheumaioid arthritis. The increase of what What genetic interaction explains this
blood indices could bc the most significant phenomenon?
for proving the diagnosis? A. Polymery
A. Additive glycosaminoglycans B. Recessive epistasis
B. Lipoproteids C. Codominance
C. Acid phosphatase D. Incomplete dominance
D. R-glycosidase E. Complementation
E. General cholesterol 130. Patients with bile ducts obstruction
125. A person felt thirsty after staying under suffer from inhibition of blood coagulation,
the conditions of hot weather for a long time. bleedings as a result of low level of vitamin
Signals of what receptors caused it first assimilation. What vitamin is in deficiency?
of all? A. E
A. Osmoreceptors of liver B. D
B. Glucoreceptors of hypothalamus C. K
C. Osmoreceptors of hypothalamus D. A
D. Baroreceptors of aortic arch E. Carotene
E. Sodium receptors of hypothalamus 131. A businessman came to India from
126. A 57-year-old patient was admitted South America. On examination the physician
to the gastroenterological department with found that the patient was suffering
suspicion of Zollinger- Ellison syndrom from sleeping-sickness.What was the way of
because of rapid increase of gastrin level invasion?
in the blood scrum. What is the most A. As a result of mosquito`s bites
probable disorder of the secretory function B. Through dirty hands
of stomach? C. With contaminated fruits and vegetables
A. Hyperacidic hyposecretion D. After contact with sick dogs
B. Hypoacidic hyposecretion E. As a result of bug's bites
C. Hyperacidic hypersecretion 132. Examination of a newborn boy's genitals
D. Hypoacidic hypersecretion revealed a cleft of urethra that opens
E. Achylia on the inferior surface of his penis. What
127. A patient with serious damage of developmental anomaly is meant?
muscular tissue was admitted to the A. Monorchism
traumatological department. What biochemical B. Hypospadia
urine index will be increased in C. Epispadia
this case? D. Cryptorchism
A. Creatinine E. Hermaphroditism

14. 133. A pregnant woman had been having performed to reveal latent toxoplasmosis
toxicosis with severe repeated vomiting and chronic gonorrhoea of the patient?
for 24 hours. In the end of the day there A.. IFA - Immunofluorescence assay
appeared tetanic convulsions and fluid loss. B. (R)CFT- Reiter's complement fixation
What shift of acid-base state caused these test
changes? C. RTHA - Reverse indirect hemagglutination
A. Excretory alkalosis assay
B. Excretory acidosis D. Immunoblot analysis
C. Metabolic acidosis E. RDHA - Reverse direct hemagglutination
D. Gaseous alkalosis assay
E. Gaseous acidosis 139. A 16-year-old boy was performed an
134. Live vaccine was injected into the appendectomy. He has been hospitalized
human body. Increasing activity of what for right lower quadrant abdominal pain
connective tissue cells can be expected? within 18 hours. The surgical specimen is
A. Adipocytes and adventitious cells edematous and erythematous. Infiltration
B. Macrophages and fibroblasts by what of the following ceils is the most
C. Fibroblasts and labrocytes typical for the process occurring here?
D. Pigmentocytes and pericytes A. Monocytes
E. Plasmocytes and lymphocytes B. Limphocytes
135. On autopsy of the 58-year-old man it C. Basophils
was revealed: mitral valve is deformed, D. Eosinophils
thickened, not totally closed. Microscopically: E. Neutrophils
foci of collagen fibers are eosinophilic, have 140. A patient who has been treated
positive fibrin reaction. The most likely it is: with diazepam on account of neurosis
A. Fibrinoid swelling complains of toothache. Doctor administered
B. Amyloidosis him an analgetic, but its dose was
C. Mucoid swelling lower then average therapeutic dose. What
D. Hyalinosis phenomenon did the doctor take into
E. Fibrinoid inflammation account while prescribing the patient an
136. A 38-year-old woman was admitted to underdose?
the admission-diagnostic department with A. Drug dependence
uterine bleeding. What are the most likely B. Cumulation
changes of blood? C. Tolerance
A. Leukopenia D. Summation
B. Leucocytosis E. Potentation
C. Reduction of haematocrite rate 141. Glomerular filtration rate (GFR)
D. Increase of haematocrite rate increased by 20% as a result of prolonged
E. Polycythemia starvation of an individual. The most evident
137. A 60-year-old patient was admitted to cause of filtration changes under this
the surgical department because of infection conditions is:
caused by blue pus bacillus (Pseudomonas A. Increase of filtration coefficient
aeruginosa) which is sensitive to penicillin B. Increase of systemic blood pressure
antibiotics. Indicate which of the given C. Decrease of oncotic pressure of blood
penicillin’s has marked activity to the plasma
Pseudomonas aeruginosa? D. Increase of penetration of the renal filter
A. Methicillin E. Increase of renal plasma stream
B. Phenoxymethylpenicillin 142. The preventive radio protector was given
C. Carbenicillin disodium to worker of a nuclear power station.
D. Oxacillin What mechanism from the below mentioned
E. Benzylpeniciilin is considered to be the male mechanism of
138. A patient who came to the doctor radioprotection?
because of his infertility was administered A. Prevention of tissue's hypoxia
to make tests for toxoplasmosis and chronic B. Inhibition of free radicals formation
gonorrhoea. Which reaction should be C. Activation of oxidation reactions

15. D. Increasing of tissue blood supply bar. Objectively: pain while moving upper
E. Increasing of respiration extremity, reduced pronation and adduction
143. Examination of initial molecular functions. Sprain of what muscle can be
structure revealed substitution of the observed here?
glutamic acid by valine. What inherited A. M. latissimus dorsi
pathology is it typical for? B. M. subscapularis
A. Hemoglobinosis C. M. romboideus major
B. Thalassemia D. M. levator scapulae
C. Minkowsky-Shauffard disease E. M. trapezius
D. Favism 149. A young man has a painlessl formation
E. Sickle-cell anemia without marked borders in the soft tissues of
144. A patient experienced a sudden his thigh. On the tissue bioptate the formation
temperature rise up to 39°C. After 6 hours looks like flesh of fish and consists of
the temperature normalized. On the 2-nd immature fibroblast-like cells with multiple
day the attack recurred: in the period of mitosis growing through the muscles. What
paroxysm the temperature reached 41°C, is the most likely diagnosis?
apyrexial period began after 8 hours. What A. Fibrosarcoma
type of temperature profile is it? B. Fibroma
A. Recurrent C. Cancer
B. Septic D. Myosarcoma
C. Continued E. Myoma
D. lntermitting 150. Analysis of amniotic fluid that was
E. Hectic obtained as a result of amniocentesis
145. Albinos can't stand sun impact - they (puncture of amniotic sac) revealed cells
don't aquire sun-tan but get sunburns. Disturbed the nuclei of which contain sex chromatin
metabolism of what aminoacid (Barr's body). What can it be evidence of?
underlies this phenomenon? A, Polyploidy
A. Glutamic acid B. Trisomy
B. Histidine C. Genetic disorders of fetus development
C. Tryptophan D. Development of female fetus
D. Phenilalanine E. Development of male fetus
E. Methionine 151. A 50-year-old patient with typhoid
146. A child has got galactosemia. fever was treated with Levomycetin,
Concentration of glucose, in blood has not next day his condition became worse,
considerably changed. Deficiency of what temperature rose to 39,6°C. What caused
enzyme caused this illness? the complication?
A. Galactose-l-phosphate uridyltransferase A. The effect of endotoxin agent
B. Hexokinase B. Reinfection
C. Galactokinase C. Secondary infection addition
D. Amylo-1.6-g1ucosidase D. Irresponsiveness of an agent to the
E. Phosphoglucomutase levomycetin
147. A. patient with suspected diphtheria E. Allergic reaction
went through bacterioscopic examination. 152. A patient with infectious mononucleosis
Examination of throat swab revealed rodshaped had been taking glucocorticoids for two
bacteria with volutin granules. weeks. He was brought into remission, but
What etiotropic preparation should he fell ill with acute attack of chronic tonsillitis.
be chosen in this case? What action of glucocorticoids caused
A. Bacteriophage this complication?
B. Interferon A. Antiallergic
C. Antidiphtheric antitoxic scrum B. Immunosuppressive
D. Diphtheria antitoxin C. Anti-inflammatory
E. Eubiotic D. Antishock
148. A young man felt acute pain in the back E. Antitoxic
during active drawing up on the horizontal 153. A 40-year-old woman was admitted to

16. the infectious diseases department with high involvement of intestines, liver, lungs. What
body temperature. Objectively: marked drug should be prescribed?
meningeal symptoms. A spinal cord punction A. Enteroseptol
was made. What anatomic formation was B. Tetracycline
puncturated? C. Quiniofone
A. Carum trigeminale D. Quingamine
B. Spatium subarachnoideum E. Metronidasol
C. Cisterna cerebellomedularis posterior 159. Tuberculosis can be treated by means
D. Spatium subdurale of combined chemotherapy that includes
E. Spatium epidurale substances with different mechanisms of
154. A patient has got a spasm of smooth action. What antituberculous medication
muscles of bronchi. Activators of what inhibits transcription of RNA into DNA in
membrane cytoreceptors are phisiologically mycobacteria?
reasoned to stop an attack? A. Isoniazid
A. β-adrenoreceptors B. Para-aminosalicylic acid
B. M-cholinoreccptors C. Rifampicin
C. α- and β-adrenoreceptors D. Ethionamide
D. H-cholinoreceptors E. Streptomycin
E. α -adrenoreceptors 160. A patient who was previously ill with
155. A patient had been taking glucocorticoids for mastectomy as a result of breast cancer was
a long time. When the preparation prescribed radiation therapy. What vitamin
was withdrawn he developed the symptoms preparation has marked radioprotective
of disease aggravation, decreased blood action caused by antioxidant activity?
pressure and weakness. What is the reason A. Ergocalciferol
of this condition? B. Tocopherol acetate
A. Appearance of adrenal insufficiency C. Thiamine chloride
B. Hyperproduction of ACTH D. Ribof1avin
C. Cumulation E. Folic acid
D. Sensibilization 161. Inhibition of α-motoneuron of the
E. Habituation extensor muscles was noticed after stimulation
156. The energy inputs of a healthy man of α-motoneuron of the flexor
have been measured. In what state was the muscles during the experiment on the spinal
patient if his energy inputs were less than cord. What type of inhibition is this process
the main exchange? based upon?
A. Rest A. Lateral
B. Nervous exertion B. Recurrent
C. Easy work C. Thiamine chloride
D. Sleep D. Presynaptic
E. Calmness E. Reciprocal
157. An 18-year-old patient came to the 162. While shifting the gaze to the closely
outpatient department with the complaints of situated object the refracting power of eye's
bleeding trauma in the vestibule of his nose. optical mediums will increase by 10 diopters.
On examination: the mechanical injury of It results from changing of such eye
the mucous layer of the vestibule without structure:
continuation into nasal cavity proper. What A. Vitreous body
is the boundary between the vestibule and B. Liquid of the anterior chamber of eye
nasal cavity proper? C Cornea
A. Nasal limen D. Lens
B. Nasal roller E. Muscle that dilatates pupil
C. Nostrils 163. In course of metabolic process active
D. Nasal septa forms of oxygen including superoxide anion
E. Choanes radical are formed in the human body. By
158. A 52-year-old patient has the following means of what enzyme is this anion inactivated?
diagnosis: systemic amebiasis with A. Peroxidase

17. B. Superoxide disffiutase ventricular arrhythmias was admitted to
C. Catalase the hospital. The patient is taking timolol
D. Glutathioneperoxidase drops for glaucoma, daily insulin injections
E. Glutathionereductase for diabetes mellitus, and an ACE inhibitor
164. A student is writing a thorough for hypertension. You have decided to use
summary of a lecture. Quality of summarizing phenytoin instead of procainamide. What is
has considerably worsened when his neighbors the reason?
started talking. What kind of inhibition A. The local anesthetic effect of procainamide
in the cerebral cortex caused this effect? would potentiate diabetes
A. Protective B. The cholinergic effects of procainamide
B. Fading would aggravate the diabetes
C. Differentiated C. The hypertensive effects of procainarmide
D. Delayed would aggravate the hypertension
E. External D. The anticholinergic effect of procainamide
165. Analeptical remedy of ret1ective type would aggravate glaucoma
from the H -cholinomimetics group was given E. The local anesthetic effect of procainamide
to the patient for restoration of breathing would aggravate the hypertension
after poisoning with carbon monoxide. 169. Tuberculine was introduced intracutaneously
What medicine was prescribed to the patient? to the child for tuberculin test. Marked
A. Lobeline hydrochloride hyperemia,
B. Mesaton tissue infiltration developed on
C. Adrenaline hydrochloride the place of injection in 24 hours. What
D. Atropine sulphate mechanism caused these modifications?
E. Pentamin A. Immunocomplex cytotoxity
166. It is planned to use the territory of an B. Antibody cytotoxity
old cattle burial ground (which is not used C. Granuloma formation
for more than 50 years) for building houses. D. Reagin type cytotoxity
But ground analysis revealed presence of E. Cell cytotoxity
the pathogen of a very dangerous illness. 170. Concentration of pyruvate is increased
Which of the indicated microorganisms is likely in the patient's blood, the most of which is
to remain in the ground for such a long excreted with urine. What avitaminosis has
time? the patient?
A. Brucella abortus A. Avitaminosis B6
B. Mycobacteriurn bovis B. Avitaminosis E
C. Francisella tubarensis C. Avitaminosis B2
D. Bacillus anthracis D. Avitaminosis B1
E. Yersinia pestis E. Avitaminosis B3
167. A 22-year-old patient was admitted 171. Upper neck node or Sympathetic trunk
to the hospital with Complaints of heavy was removed from the rabbit on experiment.
nasal breathing. During the examination Reddening and increased temperature of
of her nasal cavity the doctors found thickened the skin of head is observed. What disorder
mucous membrane, a lot of mucus of peripheral circulation of the blood has
and nodular infiltrates without erosions in developed?
the nose. The nasal rhinosc1eroma was A. Neurotonic arterial hyperemia
diagnosed. B. Neuroparalytic arterial hyperemia
The biopsy was taken. What typical C. Stasis
morphological D. Venous hyperemia
changes may be found? E. Metabolic arterial hyperemia
A. Granulomas with Larnghan's cells 172. Diagnostic scraping was performed
B. Granulomas with foreign bady cells to the woman with dysfunctional uterine
C. Interstitial inflammation bleeding. Mu1tip1e convoluted glands,
D. Granulomas with Virchow`s cells ganglially dilated lumens of some glands
E. Granulomas with Mikuliez's cel1s were revealed histologically in the scrape.
168 A 55-year-old patient with continuing Name the type or general pathological

18. process in endometry: notes that he needed to buy bigger shoes
A. Hypertrophic excrescence three times. What is the main reason of such
B. Metaplasia disproportional enlargement of different
C. Displasia parts of the body?
D. Hyperplasia glandulocystica A. Joints dystrophy development
E. Atrophy B. Increased sensitivity of the tissues to
173. While enrolling a child to school growth hormone
Mantu`s test was made to define whether C. Joints chronic inflammation development
revaccination was needed. The test result is D. Increased sensitivity of the tissues to
negative. What does this test result mean? insulin
A. Absence of antitoxic immunity to the E. Cartilaginous tissue proliferation under
tuberculosis growth hormone influence
B. Presence of cell immunity to the 178. A 54-vear-old man was admitted to the
tuberculosis hospital with complaints of pain in the right
C. Absence of cell immunity to the subcostal region, vomiting with blood.
tuberculosis Objectively: enlarged liver, varicose veins in
D. Presence of antibodies for tubercle bacillus the stomach and esophagus. Disfunction of
E. Absence of antibodies for tubercle bacillus what vessel is likely to have taken place?
174. Buffer capacity of a worker's blood was A. Vena cava superior
decreased due to exhausting muscular work. B. Vena porta
By coming of what acid substance in the C. Vena hepatica
blood can this state be explained? D. /ena cava inferior
A. α-ketoglutarate E. Aorta abdominalis
B. Lactate 179. Under SOme diseases it iS observed
C. 1,3-bisphosphoglycerate aldosteronism accompanied by hypertension
D.3-phosphoglycerate and edema due to sodium retention in
E. Pyruvate the organism. What organ of the internal
175. A man who was bitten by the unknown secretion is affected under aldosteronism?
dog applied to the surgeon. Wide ragged A. Testicle
woundes were localized on the face. What B. Pancreas
curative-prophylactic aid should be given to C. Ovaries
prevent rabies? D. Adrenal glands
A. Prescribe combined antibiotic therapy E. Hypophysis
B. Hospitalize the patient and keep under 180. Microscopic examination of the sputum
the doctor`s of a patient with pneumonia occasionally
C. Start immunisation with rabies vaccine revealed some larvae. Eosinophiles were
D. Immediately inject normal gammaglobulin detected on blood examination. What
E. Immediate injection of DPT(Diphtheria, helminthiasis can be diagnosed?
Pertusis, Tetanus) vaccine A. Enterobiosis
176. A 25-year-old patient complained of B. Opisthorchosis
the decreased vision. Accommodation disorders, C. Ascariasis
dilated pupil, lack of reaction for D. Trichocephaliasis
the light were revealed on examination. E. Paragonimiasis
What muscles function is disturbed? 181. A duodenal content smear of a patient
A. Pupil dilating muscle, ciliary with indigestion contains protosoa 10-18
B. Pupil narrowing muscle, ciliary mcm large. They have piriform bodies, 4 pairs
C. Pupil narrowing and dilating muscles of filaments, two symmetrically located
D. Inferior oblique muscle, ciliary nuclei in the broadened part of body. What
E. Lateral rectus muscle, pupil narrowing kind of the lowest organisms is it?
177. A 46-year-old patient has complained A. Larnblia
of headache, fatigue, thirst, pains in the spine and B. Dysentery ameba
joints for the last 2 years. Clinically C. Trichomonas
observed disproportional enlargement of D. Intestinal ameba
hands: feet, nose, superciliary arches. He E. Balantidium

19. 182. RNA-polymerase B(II) is blocked due A. Glutamic
to amanitine poisoning (poison of deathcup). B. Tryptophan
It disturbs: C. Tyrosine
A. Synthesis of t-RNA D. Valine
B. Synthesis of m-RNA E. Lisine
C. Maturation of m-RNA 188. Microscopic examination of the
D. Primers synthesis enlarged neck gland of a 14-year-old girl
E. Reverse transcription revealed destruction of the tissue structure
183. As a result of craniocerebral trauma of the node, absence of the lymph folli-
a patient reveals the following symptoms: cles, sclerotic areas and necrosis foci, cell
intention tremor, dysmetry, adiadochokinesis, constitution of the node is polymorphous,
dysarthria. What structure of the brain lymphocites. eosinophiles, big atypical
is injured? cells with multilobular nuclei (Beresovsky-
A. Black substance Sternberg cells) and mononuclear cells of
B. Motor cortex the large size are present. What is the most
C. Striatum likely diagnosis?
D. Pale'sphere A. Chronic lympholeucosis B.
E. Cerebellum Lymphogranulomatosis
184. Moving of the daughter chromatids to C. Berkitt's lymphoma
the poles of the cell is observed in the mitotically D. Acute lympholeucosis
dividing cell. At what stage of the E. Fungoid mycosis
mitotic cycle is this cell? 189. An isolated muscle of a frog is rhythmi-
A. Interphase cally irritated with electric impulses. Every
B. Prophase next impulse is in a period of relaxation from
C. Telophase the previus contraction. What contraction of the
D. Metaphase muscle occurs?
Ё. Anaphase A. Single
185. Autopsy of a 12-year-old girl revealed: B. Continuous (smooth) tetanus
multiple cutaneous hemorrhages (mostly C. Asynchronous
into the skin of buttocks, lower extremi- D. Tonic
ties), serous and mucous membrane E. Waved tetanus
hemorrhages, cerebral hemorrhages. 190. On autopsy it was revealed: pia mater
Adrenal glands show focal necrosis and of the upper parts of cerebral hemisphere
massive hemorrhages; kidneys show is plethoric, of yellowish-green color, soaked
necrotic nephrosis, suppurative arthritis, with purulent and fibrose exudate, looks like
iridocyclitis, vasculitis. What is the most a cap. What disease is it typical for?
probable diagnosis'? A. Grippal meningitis
A. Epidemic typhus B. Tuberculous meningitis
B. Systemic lupus erythematosus С Meningitis connected with typhus
С. Radiation sickness D. Meningococcal meningitis
D. Periarteritis nodosa E. Meningitis connected with anthrax
E. Meningococcemia 191. A 50-year-old man has felt vague
186. A patient working at a chemical abdominal discomfort within past 4
plant was admitted to the toxicological months. Physical examination revealed
department with mercury poisoning. What no lymphadenopathy, and no abdominal
medicine should be used? masses or organomegaly at palpation. Bowel
A. Isonitrozin sounds are heard. An abdominal CT scan
B. Naloxone shows a 20 cm retroperitoneal soft tissue
C. Enterosorbent mass obscuring the left psoas muscle. A
D. Unithiol stool specimen tested for occult blood is
E. Activated carbon negative. Which of the following neoplasm’s
187. Cerebral trauma caused increase of ammonia is this man most likely to have?
formation. What aminoacid takes part in removal A. Melanoma
of ammonia from cerebral tissue? B. Hamartoma C. Lipoma

20. D. Lymphoma 197. A woman who was infected with
E. Adenocarcinoma toxoplasmosis during the pregnancy has
192. A child has inhaled a button. Where is born a child with multiple congenital
it likely to be? defects. This is a result of:
A. In the esophagus A. Recombination
B. In the left main bronchus B. Cancerogenesis
C. In the larynx C. Biological mutogenesis
D. In the right main bronchus D. Chemical mutogenesis
E. In the trachea E. Teratogencsis
193. A 68-year-old woman can't move her 198. After a trauma a 44-year-old patient
upper and lower right extremities due to had a rupture of left palm muscle tendons
the stroke. Muscle tone of these extremities and and of the superficial blood vessels. After
their reflexes are increased. There are operation and removal of the most part of
pathological reflexes. What form of paralysis the necrotically changed muscle tissue the
is it? bloodstream was normalized. What vessels
A. Monoplegia have helped to restore the bloodstream?
B. Paraplegia A. Aa. metacarpeae palmares
C. Tetraplegia B. Aa.digitales palmares communes
D. Dissociation C. Arcus palmaris superficialis
E. Hemiplegia D. Aa.perforantes
194. During the fetal period of the E. Arcus palmaris profundus
development in the vascular system of 199. A patient who has been strictly keeping
the fetus a large arterial (Botallo's) to a certain diet for 10 days went through
duct is functioning which converts into examination of respiratory coefficient. It
Hg.arteriosum after birth. What anatomical was determined that it was equal 1. What
formations does this duct connect? have the patient been keeping to?
A. Aorta and superior vena cava A. With domination of proteins and fat
B. Aorta and inferior vena cava B. With domination of fat and carbohydrates
C. Pulmonary trunk and aorta C. With domination of carbohydrates
D. Right and left auricles D. Mixed
E. Pulmonary trunk and superior vena cava E. With domination of proteins and
195. An intraoperational biopsy of mammal carbohydrates
gland has revealed the signs of atypical tissue 200. A patient has tissue ischemia below the
presented by disorder of parenchyma knee joint accompanied with intermittent
stroma proportion with domination of the claudication. What artery occlusion should
last, gland structures of different size and be suspected?
shape, lined with single-layered proliferative A. Popliteal artery
epithelium. What is the most probable B. Anterior tibial artery
diagnosis? C. Proximal part of femoral artery
A. Noninfiltrative cancer D. Posterior tibial artery
B. Infiltrative cancer E. Peroneal artery
C. Papilloma
D. Fibroadenoma
E. Mastitis
196. A person was selling "homemade
pork" sausages at the market. State sanitary
inspector suspected falcification of the
sausages. What serological immune reaction
can identify food substance?
A. Agglutination test
B. Immunofluorescence test
C. Precipitation test
D. Indirect hemagglutination test
E. Complement-fixation test