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Dosis “Data Mining”

       Paul W. de Bruin

   klinisch fysicus radiologie i.o.
         Afdeling Radiologie
Leids Universitair Medisch Centrum
The Ideal World

          1. Dose data is available at the scanner after a scan
          2. Dose data is stored in an archive
          3. Statistics on dose data can be calculated (“data mining”)




DRN-Dag                                2                          10 December 2010
Californian Senate Bill no. 1237
          • 115111. (a) Commencing July 1, 2012, subject to subdivision (e), a person that uses
            a computed tomography (CT) X-ray system for human use shall record the dose of
            radiation on every CT study produced during a CT examination.
          • (b) The facility conducting the study shall electronically send each CT study and
            protocol page that lists the technical factors and dose of radiation to the electronic
            picture archiving and communications system.
          • (c) The displayed dose shall be verified annually by a medical physicist to ensure the
            displayed doses are within 20 percent of the true measured dose measured in
            accordance with subdivision (f) unless the facility is accredited.
          • (d) Subject to subdivision(e), the radiology report of a CTstudy shall include the dose
            of radiation by either recording the dose within the patient’s radiology report or
            attaching the protocol page that includes the dose of radiation to the radiology report.
          • (e) The requirements of this section shall be limited to CT systems capable of
            calculating and displaying the dose.




DRN-Dag                                             3                                  10 December 2010
DICOM/RIS/PACS/ZIS/EPD?

          • DICOM: Digital Imaging and Communications in Medicine
             • http://medical.nema.org
             • Data structures (patients, images, reports)
             • Services (storage, query, retrieval, transfer of data)
          • PACS: Picture Archiving and Communication System
             • Data archive
          • IHE: Integrating the Healthcare Enterprise
             • Workflow definition for modalities and PACS




DRN-Dag                                    4                            10 December 2010
Example Dicom - I




DRN-Dag                       5   10 December 2010
Example Dicom - II




DRN-Dag                        6   10 December 2010
Example Dicom - III




DRN-Dag                         7   10 December 2010
Dosis




DRN-Dag           8   10 December 2010
How to get dose information


          • Basic DICOM
          • DICOM SR (Structured Report)
          • Dose reports stored as “screen saves”


          • Use DICOM MPPS


          • Query PACS


          • IHE REM: defines workflow


DRN-Dag                                 9           10 December 2010
DICOM Structured Report

          • DICOM Class
          • A “databaseable document” format linked with image data
             • computer search analysis
                 • research
                 • education
                 • clinical trials
                 • data mining
          • Templates Working Groups
             • DICOM Dose SR
             • Supplement 127: CT Radiation Dose Reporting (Dose SR)




DRN-Dag                                   10                    10 December 2010
DICOM Structured Report – example text dump

     (0008,0100) SH [CODE_12]                          # 8, 1 CodeValue
     (0008,0102) SH [99_OFFIS_DCMTK]                   # 14, 1 CodingSchemeDesignator
     (0008,0104) LO [Illnesses]                        # 10, 1 CodeMeaning
     (fffe,e00d) na (ItemDelimitationItem)             # 0, 0 ItemDelimitationItem
     (fffe,e0dd) na (SequenceDelimitationItem)         # 0, 0 SequenceDelimitationItem
     (0040,a160) UT [The patient had polio at age 8, from which she made a remarkable r... # 206, 1 TextValue
     (fffe,e00d) na (ItemDelimitationItem)             # 0, 0 ItemDelimitationItem
     (fffe,e000) na (Item with undefined length #=4)   # u/l, 1 Item
     (0040,a010) CS [CONTAINS]                         # 8, 1 RelationshipType
     (0040,a040) CS [TEXT]                             # 4, 1 ValueType
     (0040,a043) SQ (Sequence with undefined length #=1)     # u/l, 1 ConceptNameCodeSequence
     (fffe,e000) na (Item with undefined length #=3)   # u/l, 1 Item
     (0008,0100) SH [CODE_13]                          # 8, 1 CodeValue
     (0008,0102) SH [99_OFFIS_DCMTK]                   # 14, 1 CodingSchemeDesignator
     (0008,0104) LO [Allergies]                         # 10, 1 CodeMeaning
     (fffe,e00d) na (ItemDelimitationItem)             # 0, 0 ItemDelimitationItem
     (fffe,e0dd) na (SequenceDelimitationItem)         # 0, 0 SequenceDelimitationItem
     (0040,a160) UT [ALLERGIC TO PENICILLIN. She denies any other drug or food allergies.] # 68, 1 TextValue




DRN-Dag                                                 11                                         10 December 2010
DICOM Structured Report - Example

  “The finding is a mass
  measuring 1.3 cm in
  diameter with an infiltrative
  margination.
  The conclusion is a
  probable malignancy,
  inferred from the infiltrative
  margination of the mass.”




Hussein et al. DICOM structured reporting: Part 1. Overview and characteristics. Radiographics : a review publication of the
Radiological Society of North America, Inc (2004) vol. 24 (3) pp. 891-6

David A. Clunie, DICOM Structured Reporting, ISBN 0-9701369-0-0, out of print. PDF at: http://www.pixelmed.com/srbook.html

  DRN-Dag                                                        12                                            10 December 2010
Dosis Report – Screen Shot - EVAR




DRN-Dag                          13           10 December 2010
Dose Report – Screen Shot - 1




DRN-Dag                           14      10 December 2010
Dose Report – Screen Shot – 2




DRN-Dag                          15       10 December 2010
Dose Utility – David Clunie




              http://www.dclunie.com/pixelmed/software/webstart/DoseUtilityUsage.html

DRN-Dag                                        16                                   10 December 2010
DICOM Modality Performed Procedure Step




                                    Bron: Brain Sanderse, ICT Architect, Amphia Ziekenhuis

DRN-Dag                        17                                     10 December 2010
Commercieel beschikbaar (http://www.krucom.com)




DRN-Dag                         18                   10 December 2010
Query the PACS




          1. Via vendor interface


          2. Using the DICOM interface




DRN-Dag                             19   10 December 2010
DICOM Patient-Study-Series-Image Model

          Patient     Study                Series           Image

                                                                PA
           Jansen    CT Onderzoek             Scout             LR



                                                              Image 1
                                         Anatomische scan


                                                              Image …



                                                             Image 200




                                             Contrast         Image 1


                                                              Image …



                                                             Image 600




DRN-Dag                             20                      10 December 2010
Work flow

• Query PACS for studies on a date
• For each study query PACS for
  series (filter on CT/DX/MAMMO)
• For each series query PACS for
  images
• Retrieve each image
    • Throw away image data
    • Store dose information in local
      database




DRN-Dag                                 21   10 December 2010
Why so complicated?

          • Patient-Study-Series-Image is dictated by DICOM
          • Attributes are defined at different levels:
             • Modality is defined at Series level.
             • Dose information is defined at Image level.
          • No support for optimized generic batch retrieval.
          • PACS has limit on number of query results




DRN-Dag                                   22                    10 December 2010
CT Dose from DICOM Images




García et al. Automated effective dose estimation in CT. Radiat Prot Dosimetry (2010) vol. 138 (1) pp. 71-7


DRN-Dag                                              23                                     10 December 2010
CT Dose from DICOM Images




DRN-Dag                       24      10 December 2010
Dose monitoring is a hot topic




DRN-Dag                           25       10 December 2010
Concluding
                  Storage                             Data Mining/Retrieval
•Basic DICOM                                   •Query PACS
     • Standard dose parameters
                                                    • Using PACS functionality provided by
     • Basic modality support
                                                      vendor
•DICOM SR (Structured Report)
                                                         • rare
     • Not implemented (yet) by most vendors
     • “Best solution”                              • Using DICOM interface
•Dose reports stored as “screen saves”                   • Generic
     • Better than nothing or manual lists               • Brute-force
     • Implemented by most vendors                       • Slow
     • Can be converted to DICOM SR                 • Generic
•DICOM MPPS
                                                         • Can only retrieve what is in the
     • Dose information via messages,
                                                           PACS
       messages are not stored
     • Cannot go back in PACS history
     • Commercial third-party solution
       available
•Generic
     • History?



DRN-Dag                                        26                                    10 December 2010

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17. dose data mining, de bruin

  • 1. Dosis “Data Mining” Paul W. de Bruin klinisch fysicus radiologie i.o. Afdeling Radiologie Leids Universitair Medisch Centrum
  • 2. The Ideal World 1. Dose data is available at the scanner after a scan 2. Dose data is stored in an archive 3. Statistics on dose data can be calculated (“data mining”) DRN-Dag 2 10 December 2010
  • 3. Californian Senate Bill no. 1237 • 115111. (a) Commencing July 1, 2012, subject to subdivision (e), a person that uses a computed tomography (CT) X-ray system for human use shall record the dose of radiation on every CT study produced during a CT examination. • (b) The facility conducting the study shall electronically send each CT study and protocol page that lists the technical factors and dose of radiation to the electronic picture archiving and communications system. • (c) The displayed dose shall be verified annually by a medical physicist to ensure the displayed doses are within 20 percent of the true measured dose measured in accordance with subdivision (f) unless the facility is accredited. • (d) Subject to subdivision(e), the radiology report of a CTstudy shall include the dose of radiation by either recording the dose within the patient’s radiology report or attaching the protocol page that includes the dose of radiation to the radiology report. • (e) The requirements of this section shall be limited to CT systems capable of calculating and displaying the dose. DRN-Dag 3 10 December 2010
  • 4. DICOM/RIS/PACS/ZIS/EPD? • DICOM: Digital Imaging and Communications in Medicine • http://medical.nema.org • Data structures (patients, images, reports) • Services (storage, query, retrieval, transfer of data) • PACS: Picture Archiving and Communication System • Data archive • IHE: Integrating the Healthcare Enterprise • Workflow definition for modalities and PACS DRN-Dag 4 10 December 2010
  • 5. Example Dicom - I DRN-Dag 5 10 December 2010
  • 6. Example Dicom - II DRN-Dag 6 10 December 2010
  • 7. Example Dicom - III DRN-Dag 7 10 December 2010
  • 8. Dosis DRN-Dag 8 10 December 2010
  • 9. How to get dose information • Basic DICOM • DICOM SR (Structured Report) • Dose reports stored as “screen saves” • Use DICOM MPPS • Query PACS • IHE REM: defines workflow DRN-Dag 9 10 December 2010
  • 10. DICOM Structured Report • DICOM Class • A “databaseable document” format linked with image data • computer search analysis • research • education • clinical trials • data mining • Templates Working Groups • DICOM Dose SR • Supplement 127: CT Radiation Dose Reporting (Dose SR) DRN-Dag 10 10 December 2010
  • 11. DICOM Structured Report – example text dump (0008,0100) SH [CODE_12] # 8, 1 CodeValue (0008,0102) SH [99_OFFIS_DCMTK] # 14, 1 CodingSchemeDesignator (0008,0104) LO [Illnesses] # 10, 1 CodeMeaning (fffe,e00d) na (ItemDelimitationItem) # 0, 0 ItemDelimitationItem (fffe,e0dd) na (SequenceDelimitationItem) # 0, 0 SequenceDelimitationItem (0040,a160) UT [The patient had polio at age 8, from which she made a remarkable r... # 206, 1 TextValue (fffe,e00d) na (ItemDelimitationItem) # 0, 0 ItemDelimitationItem (fffe,e000) na (Item with undefined length #=4) # u/l, 1 Item (0040,a010) CS [CONTAINS] # 8, 1 RelationshipType (0040,a040) CS [TEXT] # 4, 1 ValueType (0040,a043) SQ (Sequence with undefined length #=1) # u/l, 1 ConceptNameCodeSequence (fffe,e000) na (Item with undefined length #=3) # u/l, 1 Item (0008,0100) SH [CODE_13] # 8, 1 CodeValue (0008,0102) SH [99_OFFIS_DCMTK] # 14, 1 CodingSchemeDesignator (0008,0104) LO [Allergies] # 10, 1 CodeMeaning (fffe,e00d) na (ItemDelimitationItem) # 0, 0 ItemDelimitationItem (fffe,e0dd) na (SequenceDelimitationItem) # 0, 0 SequenceDelimitationItem (0040,a160) UT [ALLERGIC TO PENICILLIN. She denies any other drug or food allergies.] # 68, 1 TextValue DRN-Dag 11 10 December 2010
  • 12. DICOM Structured Report - Example “The finding is a mass measuring 1.3 cm in diameter with an infiltrative margination. The conclusion is a probable malignancy, inferred from the infiltrative margination of the mass.” Hussein et al. DICOM structured reporting: Part 1. Overview and characteristics. Radiographics : a review publication of the Radiological Society of North America, Inc (2004) vol. 24 (3) pp. 891-6 David A. Clunie, DICOM Structured Reporting, ISBN 0-9701369-0-0, out of print. PDF at: http://www.pixelmed.com/srbook.html DRN-Dag 12 10 December 2010
  • 13. Dosis Report – Screen Shot - EVAR DRN-Dag 13 10 December 2010
  • 14. Dose Report – Screen Shot - 1 DRN-Dag 14 10 December 2010
  • 15. Dose Report – Screen Shot – 2 DRN-Dag 15 10 December 2010
  • 16. Dose Utility – David Clunie http://www.dclunie.com/pixelmed/software/webstart/DoseUtilityUsage.html DRN-Dag 16 10 December 2010
  • 17. DICOM Modality Performed Procedure Step Bron: Brain Sanderse, ICT Architect, Amphia Ziekenhuis DRN-Dag 17 10 December 2010
  • 19. Query the PACS 1. Via vendor interface 2. Using the DICOM interface DRN-Dag 19 10 December 2010
  • 20. DICOM Patient-Study-Series-Image Model Patient Study Series Image PA Jansen CT Onderzoek Scout LR Image 1 Anatomische scan Image … Image 200 Contrast Image 1 Image … Image 600 DRN-Dag 20 10 December 2010
  • 21. Work flow • Query PACS for studies on a date • For each study query PACS for series (filter on CT/DX/MAMMO) • For each series query PACS for images • Retrieve each image • Throw away image data • Store dose information in local database DRN-Dag 21 10 December 2010
  • 22. Why so complicated? • Patient-Study-Series-Image is dictated by DICOM • Attributes are defined at different levels: • Modality is defined at Series level. • Dose information is defined at Image level. • No support for optimized generic batch retrieval. • PACS has limit on number of query results DRN-Dag 22 10 December 2010
  • 23. CT Dose from DICOM Images García et al. Automated effective dose estimation in CT. Radiat Prot Dosimetry (2010) vol. 138 (1) pp. 71-7 DRN-Dag 23 10 December 2010
  • 24. CT Dose from DICOM Images DRN-Dag 24 10 December 2010
  • 25. Dose monitoring is a hot topic DRN-Dag 25 10 December 2010
  • 26. Concluding Storage Data Mining/Retrieval •Basic DICOM •Query PACS • Standard dose parameters • Using PACS functionality provided by • Basic modality support vendor •DICOM SR (Structured Report) • rare • Not implemented (yet) by most vendors • “Best solution” • Using DICOM interface •Dose reports stored as “screen saves” • Generic • Better than nothing or manual lists • Brute-force • Implemented by most vendors • Slow • Can be converted to DICOM SR • Generic •DICOM MPPS • Can only retrieve what is in the • Dose information via messages, PACS messages are not stored • Cannot go back in PACS history • Commercial third-party solution available •Generic • History? DRN-Dag 26 10 December 2010