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Cell Structure and Function
Jayesh Patidar
www.drjayeshpatidar.blogspot.com
Cells
• Smallest living unit
• Most are microscopic
www.drjayeshpatidar.blogspot.in
Discovery of Cells
• Robert Hooke (mid-1600s)
– Observed sliver of cork
– Saw “row of empty boxes”
– Coined the term cell
www.drjayeshpatidar.blogspot.in
Cell theory
• (1839)Theodor Schwann & Matthias Schleiden
“ all living things are made of cells”
• (50 yrs. later) Rudolf Virchow
“all cells come from cells”
www.drjayeshpatidar.blogspot.in
Principles of Cell Theory
• All living things are made of cells
• Smallest living unit of structure and
function of all organisms is the cell
• All cells arise from preexisting cells
(this principle discarded the idea of
spontaneous generation)
www.drjayeshpatidar.blogspot.in
Cell Size
www.drjayeshpatidar.blogspot.in
Cells Have Large Surface
Area-to-Volume Ratio
www.drjayeshpatidar.blogspot.in
Characteristics of All Cells
• A surrounding membrane
• Protoplasm – cell contents in thick fluid
• Organelles – structures for cell function
• Control center with DNA
www.drjayeshpatidar.blogspot.in
Cell Types
• Prokaryotic
• Eukaryotic
www.drjayeshpatidar.blogspot.in
Prokaryotic Cells
• First cell type on earth
• Cell type of Bacteria and Archaea
www.drjayeshpatidar.blogspot.in
Prokaryotic Cells
• No membrane bound nucleus
• Nucleoid = region of DNA concentration
• Organelles not bound by membranes
www.drjayeshpatidar.blogspot.in
Eukaryotic Cells
• Nucleus bound by membrane
• Include fungi, protists, plant,
and animal cells
• Possess many organelles
Protozoanwww.drjayeshpatidar.blogspot.in
Representative Animal Cell
www.drjayeshpatidar.blogspot.in
Representative Plant Cell
www.drjayeshpatidar.blogspot.in
Organelles
• Cellular machinery
• Two general kinds
– Derived from membranes
– Bacteria-like organelles
www.drjayeshpatidar.blogspot.in
Bacteria-Like Organelles
• Derived from symbiotic bacteria
• Ancient association
• Endosymbiotic theory
– Evolution of modern cells from
cells & symbiotic bacteria
www.drjayeshpatidar.blogspot.in
Plasma Membrane
• Contains cell contents
• Double layer of phospholipids & proteins
www.drjayeshpatidar.blogspot.in
Phospholipids
• Polar
– Hydrophylic head
– Hydrophobic tail
• Interacts with water
www.drjayeshpatidar.blogspot.in
Movement Across the Plasma Membrane
• A few molecules move freely
– Water, Carbon dioxide, Ammonia, Oxygen
• Carrier proteins transport some molecules
– Proteins embedded in lipid bilayer
– Fluid mosaic model – describes fluid nature of
a lipid bilayer with proteins
www.drjayeshpatidar.blogspot.in
www.drjayeshpatidar.blogspot.in
Membrane Proteins
1. Channels or transporters
– Move molecules in one direction
2. Receptors
– Recognize certain chemicals
www.drjayeshpatidar.blogspot.in
Membrane Proteins
3. Glycoproteins
– Identify cell type
4. Enzymes
– Catalyze production of substances
www.drjayeshpatidar.blogspot.in
Cell Walls
• Found in plants, fungi, & many protists
• Surrounds plasma membrane
www.drjayeshpatidar.blogspot.in
Cell Wall Differences
• Plants – mostly cellulose
• Fungi – contain chitin
www.drjayeshpatidar.blogspot.in
Cytoplasm
• Viscous fluid containing organelles
• components of cytoplasm
– Interconnected filaments & fibers
– Fluid = cytosol
– Organelles (not nucleus)
– storage substances
www.drjayeshpatidar.blogspot.in
Cytoskeleton
• Filaments & fibers
• Made of 3 fiber types
– Microfilaments
– Microtubules
– Intermediate filaments
• 3 functions:
– mechanical support
– anchor organelles
– help move
substances
www.drjayeshpatidar.blogspot.in
A = actin, IF = intermediate filament, MT = microtubule
www.drjayeshpatidar.blogspot.in
Cilia & Flagella
• Provide motility
• Cilia
– Short
– Used to move substances
outside human cells
• Flagella
– Whip-like extensions
– Found on sperm cells
• Basal bodies like
centrioles
www.drjayeshpatidar.blogspot.in
Cilia & Flagella Structure
• Bundles of microtubules
• With plasma membrane
www.drjayeshpatidar.blogspot.in
Centrioles
• Pairs of microtubular structures
• Play a role in cell division
www.drjayeshpatidar.blogspot.in
Membranous Organelles
• Functional components within cytoplasm
• Bound by membranes
www.drjayeshpatidar.blogspot.in
Nucleus
• Control center of cell
• Double membrane
• Contains
– Chromosomes
– Nucleolus
www.drjayeshpatidar.blogspot.in
Nuclear Envelope
• Separates nucleus from rest of cell
• Double membrane
• Has pores
www.drjayeshpatidar.blogspot.in
DNA
• Hereditary material
• Chromosomes
– DNA
– Protiens
– Form for cell division
• Chromatin
www.drjayeshpatidar.blogspot.in
Nucleolus
• Most cells have 2 or more
• Directs synthesis of RNA
• Forms ribosomes
www.drjayeshpatidar.blogspot.in
Endoplasmic Reticulum
• Helps move substances within cells
• Network of interconnected membranes
• Two types
– Rough endoplasmic reticulum
– Smooth endoplasmic reticulum
www.drjayeshpatidar.blogspot.in
Rough Endoplasmic Reticulum
• Ribosomes attached to surface
– Manufacture protiens
– Not all ribosomes attached to rough ER
• May modify proteins from ribosomes
www.drjayeshpatidar.blogspot.in
Smooth Endoplasmic Reticulum
• No attached ribosomes
• Has enzymes that help build molecules
– Carbohydrates
– Lipids
www.drjayeshpatidar.blogspot.in
Golgi Apparatus
• Involved in synthesis of plant cell wall
• Packaging & shipping station of cell
www.drjayeshpatidar.blogspot.in
Golgi Apparatus Function
1. Molecules come in vesicles
2. Vesicles fuse with Golgi membrane
3. Molecules may be modified by Golgi
www.drjayeshpatidar.blogspot.in
Golgi Apparatus Function
(Continued)
4. Molecules pinched-off in separate vesicle
5. Vesicle leaves Golgi apparatus
6. Vesicles may combine with plasma
membrane to secrete contents
www.drjayeshpatidar.blogspot.in
www.drjayeshpatidar.blogspot.in
Lysosomes
• Contain digestive enzymes
• Functions
– Aid in cell renewal
– Break down old cell parts
– Digests invaders
www.drjayeshpatidar.blogspot.in
Vacuoles
• Membrane bound storage sacs
• More common in plants than animals
• Contents
– Water
– Food
– wastes
www.drjayeshpatidar.blogspot.in
Bacteria-Like Organelles
• Release & store energy
• Types
– Mitochondria
(release energy)
– Chloroplasts
(store energy)
www.drjayeshpatidar.blogspot.in
Mitochondria
• Have their own DNA
• Bound by double membrane
www.drjayeshpatidar.blogspot.in
Mitochondria
• Break down fuel molecules (cellular respiration)
– Glucose
– Fatty acids
• Release energy
– ATP
www.drjayeshpatidar.blogspot.in
Chloroplasts
• Derived form photosynthetic bacteria
• Solar energy capturing organelle
www.drjayeshpatidar.blogspot.in
Photosynthesis
• Takes place in the chloroplast
• Makes cellular food – glucose
www.drjayeshpatidar.blogspot.in
Review of Eukaryotic Cells
www.drjayeshpatidar.blogspot.in
Review of Eukaryotic Cells
www.drjayeshpatidar.blogspot.in
www.drjayeshpatidar.blogspot.in
Molecule Movement & Cells
• Passive Transport
• Active Transport
• Endocytosis
(phagocytosis & pinocytosis)
• Exocytosis
www.drjayeshpatidar.blogspot.in
Passive Transport
• No energy required
• Move due to gradient
– differences in concentration, pressure, charge
• Move to equalize gradient
– High moves toward low
www.drjayeshpatidar.blogspot.in
Types of Passive Transport
1. Diffusion
2. Osmosis
3. Facilitated diffusion
www.drjayeshpatidar.blogspot.in
Diffusion
• Molecules move to equalize concentration
www.drjayeshpatidar.blogspot.in
Osmosis
• Special form of diffusion
• Fluid flows from lower solute concentration
• Often involves movement of water
– Into cell
– Out of cell
www.drjayeshpatidar.blogspot.in
Solution Differences & Cells
• solvent + solute = solution
• Hypotonic
– Solutes in cell more than outside
– Outside solvent will flow into cell
• Isotonic
– Solutes equal inside & out of cell
• Hypertonic
– Solutes greater outside cell
– Fluid will flow out of cell
www.drjayeshpatidar.blogspot.in
www.drjayeshpatidar.blogspot.in
Facilitated Diffusion
• Differentially permeable membrane
• Channels (are specific) help molecule
or ions enter or leave the cell
• Channels usually are transport proteins
(aquaporins facilitate the movement of
water)
• No energy is used
www.drjayeshpatidar.blogspot.in
Process of Facilitated Transport
• Protein binds with molecule
• Shape of protein changes
• Molecule moves across membrane
www.drjayeshpatidar.blogspot.in
Active Transport
• Molecular movement
• Requires energy (against gradient)
• Example is sodium-potassium pump
www.drjayeshpatidar.blogspot.in
Endocytosis
• Movement of large material
– Particles
– Organisms
– Large molecules
• Movement is into cells
• Types of endocytosis
– bulk-phase (nonspecific)
– receptor-mediated (specific)
www.drjayeshpatidar.blogspot.in
Process of Endocytosis
• Plasma membrane surrounds material
• Edges of membrane meet
• Membranes fuse to form vesicle
www.drjayeshpatidar.blogspot.in
Forms of Endocytosis
• Phagocytosis – cell eating
• Pinocytosis – cell drinking
www.drjayeshpatidar.blogspot.in
Exocytosis
• Reverse of endocytosis
• Cell discharges material
www.drjayeshpatidar.blogspot.in
Exocytosis
• Vesicle moves to cell surface
• Membrane of vesicle fuses
• Materials expelled
www.drjayeshpatidar.blogspot.in
www.drjayeshpatidar.blogspot.in
Thank You
www.drjayeshpatidar.blogspot.in

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Human cell & it's function